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Topic: Single photon emission computed tomography

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	SPECT scan\| Single Photon Emission Computed Tomography \| Mayfield Clinic
		Before the SPECT scan, you are injected with a chemical that is radiolabled, meaning it emits gamma rays that can be detected by the scanner.
		SPECT scanning is also useful for pre-surgical evaluation of medically uncontrolled seizures (Figure 1).
		The radioisotopes typically used in SPECT to label tracers are iodine-123, technetium-99m, xenon-133, thallium-201, and fluorine-18.
	www.mayfieldclinic.com /PE-SPECT.htm (773 words)

	Single photon emission computed tomography scanning in the diagnosis of knee pathology Journal of Orthopaedic Surgery - ... (Site not responding. Last check: 2007-10-08)
		SPECT bone scan appears to be useful in the diagnosis of knee pathology in routine practice and in selecting patients for arthroscopy, especially most useful for the diagnosis of medial meniscal tears.
		SPECT scanning has proved a useful alternative to MRI and also has an important role where MRI is contraindicated and when examination of other structures such as hips is required.15 The purpose of this study was to evaluate the role of SPECT imaging in a routine clinical setting.
		All SPECT scans were interpreted by an experienced specialist in nuclear medicine, and arthroscopy was performed by or was supervised by an experienced orthopaedic surgeon-either a consultant (n=27) or a registrar (n=13).
	www.findarticles.com /p/articles/mi_qa3794/is_200406/ai_n9425220 (840 words)

	Single photon emission computed tomography - Definition, Description
		Single photon emission computed tomography (SPECT) is an imaging study that uses radioactive materials injected through a vein that will pass into the brain generating a high-resolution brain image.
		SPECT is used to diagnose head trauma, epilepsy, dementia, and cerebrovascular disease.
		SPECT allows clinicians to visualize a specific area of the brain called the striatum, which contains a neurotransmitter (a chemical that communicates nerve impulse from one nerve cell to another) called dopamine.
	www.minddisorders.com /Py-Z/Single-photon-emission-computed-tomography.html (534 words)

	Single Proton Emission Computed Tomography Information on Healthline
		SPECT detects the course of a radioactive substance that is injected, ingested, or inhaled.
		SPECT can locate the site of origin of a seizure, can confirm the type of seizure that has occurred, and can provide information that is useful in the determination of therapy.
		SPECT produces two-dimensional and three-dimensional images of a target region in the body by detecting the presence and location of a radioactive compound given prior to the test.
	www.healthline.com /galecontent/single-proton-emission-computed-tomography (846 words)

	SPECT Scan - Page 2
		SPECT scans have also been used to predict potential heart problems for patients with diabetes who are unable to exercise and are at high risk for heart attack.
		SPECT scans are also being used in the diagnosis and evaluation of tumors in the breast and other areas, including the brain.
		However, SPECT is often used as an initial assessment to avoid a coronary angiogram because SPECT is noninvasive and relatively inexpensive.
	heart.healthcentersonline.com /radionuclideimaging/SPECT2.cfm (802 words)

	Single Photon Emission Computed Tomography of Pulmonary Emboli and Venous Thrombi Using Anti-D-Dimer American Journal ... (Site not responding. Last check: 2007-10-08)
		For example, ventilation/perfusion scanning is prone to a high number of nondiagnostic results (2), and the sensitivity of contrast-enhanced computed tomography scanning has been reported to be as low as 70% (3).
		This problem might be solved by using single photon emission computed tomography (SPECT) to spatially resolve PEs from the thoracic blood pool background.
		SPECT is a nuclear medicine imaging technique that, like X-ray computed tomography, creates two-dimensional or three-dimensional tomographic images of the body.
	www.findarticles.com /p/articles/mi_qa4085/is_200405/ai_n9435951 (980 words)

	Medical Policy RAD.00023 \| SPECT (Single Photon Emission Computed Tomography) Scans and Scintimammography
		SPECT scanning is an established imaging modality for a number of different conditions.
		SPECT Scans are considered not medically necessary for the evaluation or management of cerebrovascular accident (CVA, stroke), subarachnoid hemorrhage, or transient ischemic attack.
		SPECT is typically performed without the need of a hospital stay. The patient is given a dose of a radiotracer, which circulates in the bloodstream and binds to specific target cells.
	medpolicy.bluecrossca.com /policies/RAD/SPECT.html (1929 words)

	Positron and Single Photon Emission Tomography
		-ray) emissions of the specific isotopes employed and the sensitivity and sophistication of the instruments used to detect them, the two-dimensional distribution of radioactivity within a brain slice may be inferred from outside of the head.
		Whereas PET and SPECT rely on similar principles to produce their images, important differences in instrumentation, radiochemistry, and experimental applications are dictated by inherent differences in their respective physics of photon emission.
		However, the emission of a single photon means that instrumentation in SPECT must be intrinsically different from that in PET.
	www.acnp.org /g4/GN401000088/CH087.html (8023 words)

	BioMed Central \| Full text \| Single photon emission computed tomography (SPECT) of anxiety disorders before and after ...
		After completion of the rest period, SPECT imaging of the brain was performed, with the subject's head supported by a headrest, using a dual detector gamma camera (Elscint, Helix, GE Medical Systems, USA) equipped with fan beam collimators.
		Data were acquired in the step-and-shoot mode, using a 360 degree circular orbit, with the detectors of the gamma camera as close as possible to the subject's head.
		The lower spatial resolution of SPECT may be considered a limitation nevertheless this study usefully emphasizes the importance of limbic regions (amygdala, hippocampus) in mediating anxiety.
	www.biomedcentral.com /1471-244X/4/30 (4058 words)

	Single Photon Emission Computed Tomography (SPECT) for the Diagnosis of ADD/ADHD, Dementias and Other Psychiatric ...
		Dementias are characterized by the development of multiple cognitive deficits, including memory impairment, that are due to the direct physiological effects of a general medical condition (e.g., hypothyroidism, Parkinson’s disease, head trauma), to the persisting effects of a substance, or to multiple etiologies (e.g., the combined effects of cerebrovascular disease and Alzheimer’s disease).
		Single photon emission computed tomography (SPECT) has been proposed as a tool to diagnose and estimate response to treatment in ADHD, dementias, and other psychiatric conditions (e.g., major depression).
		SPECT images are formed from detection of gamma rays emitted during the decay of the radionuclide.
	www.regence.com /trgmedpol/radiology/rad44.html (1480 words)

	The Basics of Brain Imaging
		PET measures emissions from radioactively labeled chemicals that have been injected into the bloodstream and uses the data to produce two- or three-dimensional images of the distribution of the chemicals throughout the brain and body.
		A computer uses the data gathered by the sensors to construct multicolored two- or three-dimensional images that show where the compound acts in the brain.
		SPECT tracers also deteriorate more slowly than many PET tracers, which means that SPECT studies require longer test and retest periods than PET studies do.
	www.nida.nih.gov /NIDA_Notes/NNVol11N5/Basics.html (1142 words)

	Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) Scans - MC (Site not responding. Last check: 2007-10-08)
		Single photon emission computed tomography (SPECT) scans and PET scans are part of the nuclear imaging family.
		In the event that a patient has received a single photon computed tomography test (SPECT) with inconclusive results; a PET scan will be covered.
		Whole body PET scan results and results of concurrent computed tomography (CT) and follow-up lymph node biopsy--PET scans must be properly coordinated with other diagnostic modalities.
	www.healthpartners.com:747 /medicare/pet_spect_mc.html (1853 words)

	Prevalence of myocardial viability assessed by single photon emission computed tomography in patients with chronic ...
		Prevalence of myocardial viability assessed by single photon emission computed tomography in patients with chronic ischaemic left ventricular dysfunction -- Schinkel et al.
		Prevalence of myocardial viability as detected by positron emission tomography in patients with ischemic cardiomyopathy.
		Dobutamine stress echocardiography and technetium-99m-tetrofosmin/fluorine 18-fluorodeoxyglucose single-photon emission computed tomography and influence of resting ejection fraction to assess myocardial viability in patients with severe left ventricular dysfunction and healed myocardial infarction.
	heart.bmjjournals.com /cgi/content/full/88/2/125 (3708 words)

	The Use of Positron Emission Tomography (PET) and Single-Photon-Emission Computed Tomography (SPECT) in Toxic Tort ...
		The worst case is that plaintiffs are permitted to introduce the PET or SPECT scans to demonstrate that the plaintiff's brain is abnormal as a result of some toxic exposure and that the abnormality has resulted in an injury such as cognitive impairment to the plaintiff.
		Plaintiff's neurologist and internist were allowed to testify that a SPECT scan of plaintiff's brain showed areas of decreased blood circulation in the left frontal lobe consistent with the diagnosis of chronic toxic encephalopathy.
		The court stated that SPECT has "been the subject of much criticism by the scientific community as not having met acceptable scientific levels of methodology and criteria, and [is] not designed to test for the recognized medical condition of chemical sensitivity." 897 F. Supp.
	www.morankikerbrown.com /CM/Articles/Articles103.asp (2117 words)

	Clinical Trial: Single Photon Emission Computed Tomography (SPECT) to Study Paroxysmal Hyperkinetic Movement Disorders
		SPECT is a nuclear medicine test that produces three-dimensional images of the brain, showing blood flow and function in different brain regions.
		For the scan, the subject lies on an examination table and the SPECT camera is moved near and around the head to image the brain.
		Ictal SPECT is a reliable method to detect a seizure focus during an epileptic seizure.
	www.clinicaltrials.gov /ct/show/NCT00051337 (1147 words)

	Contribution of Single-Photon Emission Computed Tomography in the Diagnosis and Follow-Up of CNS Toxicity of a ... (Site not responding. Last check: 2007-10-08)
		Contribution of Single-Photon Emission Computed Tomography in the Diagnosis and Follow-Up of CNS Toxicity of a Cytarabine-Containing Regimen in Pediatric Leukemia -- Véra et al.
		Contribution of Single-Photon Emission Computed Tomography in the Diagnosis and Follow-Up of CNS Toxicity of a Cytarabine-Containing Regimen in Pediatric Leukemia
		Computed tomography of the brain is usually normal during
	www.jco.org /cgi/content/full/17/9/2804 (2659 words)

	Computed Tomography Information on Healthline
		Computed tomography (CT) scanning is a valuable diagnostic tool that provides physicians with views of internal body structures.
		During a CT scan, multiple x rays are passed through the body, producing cross-sectional images, or "slices, " on a cathode-ray tube (CRT), a device resembling a television screen.
		Computed tomography, also called CT scan, CAT scan, or computerized axial tomography, is a combination of focused x-ray beams and the computerized production of an image.
	www.healthline.com /galecontent/computed-tomography-1 (979 words)

	basic MR imaging (Site not responding. Last check: 2007-10-08)
		Non-tomographic images represent "projections" from a single point of view and include bolus contrast x-ray angiograms and MR angiograms.
		CT (roentgen-ray computed tomography) A beam of x-rays is shot straight through the brain.
		SPECT/PET (single photon/positron emission computed tomography) When radiolabeled compounds are injected in tracer amounts, their photon emissions can be detected much like x-rays in CT. The images made represent the accumulation of the labeled compound.
	www.med.harvard.edu /AANLIB/hms1.html (400 words)

	[Single-photon emission-computed tomography in the differential diagnosis of dementia]
		To assess the value of single photon emission computed tomography (SPECT) in the differential diagnosis of dementia SPECT and conventional computed tomography were performed in 77 patients (50 men, 27 women, mean age 59 [28-90] years) with dementia diagnosed by a battery of psychometric tests.
		All 21 patients with dementia due to Huntington's chorea showed a typical pattern with absent perfusion of the head of the caudate nucleus, although in three of them conventional computed tomography didn't demonstrate complete atrophy of this structure.
		Single photon emission computed tomography can make a contribution to the diagnosis and classification of primary degenerative dementias and can be used to differentiate them from other forms of dementia.
	www.aegis.com /aidsline/1990/feb/M9020135.html (481 words)

	Critical Care \| Full text \| Use of single photon emission computed tomography (SPECT) in the follow-up of carbon ...
		We experienced two cases of CO poisoning in which SPECT was performed 1 month later from acute poisoning; they had different outcome and the clinical situation was directly related to SPECT imaging results.
		The SPECT brain imaging was totally negative for the younger and showed a bilateral decrease of blood flow in the subcortical motor nuclei in the older patient.
		We can conclude that SPECT imaging is more sensitive and more directly related with the clinical picture of the patient than MRI and we are strongly convinced to use this diagnostic test in all cases of severe carbon monoxide poisoning.
	ccforum.com /content/2/S1/P072 (492 words)

	Diagnostic and prognostic value of dobutamine thallium-201 single-photon emission computed tomography after heart ...
		SPECT was considered abnormal in the presence of reversible or fixed defects in >/=2 segments.
		The sensitivity, specificity, positive predictive value and negative predictive value of SPECT for the detection of significant angiographic CAV were 89%, 71%, 42% and 96%, respectively.
		CONCLUSIONS: Dobutamine (201)Tl SPECT is a useful method for detecting patients with significant CAV and assessing prognosis.
	hearttransplant.researchtoday.net /archive/1/5/204.htm (409 words)

	Early single-photon emission computed tomography in mild head trauma. A controlled study.
		Although computed tomography (CT) and magnetic resonance imaging scans often appear normal after mild head trauma, many patients experience attentional or other cognitive disturbances that are difficult to quantify by neuropsychological testing in the absence of a premorbid profile.
		None of the SPECT results from normal control subjects were read as trauma.
		SPECT is more sensitive than CT in detecting brain injury after mild head trauma.
	www.aegis.com /aidsline/1995/feb/M9520866.html (417 words)

	Single-Photon Emission Computed Tomography Using Hexamethylpropyleneamine Oxime in the Prognosis of Acute Cerebral ... (Site not responding. Last check: 2007-10-08)
		Single-Photon Emission Computed Tomography Using Hexamethylpropyleneamine Oxime in the Prognosis of Acute Cerebral Infarction -- Bowler et al.
		SPECT is a well-validated proportional indicator of cerebral perfusion
		Single-photon emission computed tomography and early death in acute ischemic stroke.
	stroke.ahajournals.org /cgi/content/full/27/1/82 (3582 words)

	Early single photon emission computed tomography in Sturge-Weber syndrome -- Pinton et al. 63 (5): 616 -- Journal of ... (Site not responding. Last check: 2007-10-08)
		SPECT therefore detects CBF asymmetry in infants with Sturge-Weber disease, which tends to shift with age.
		Scale represents the CBF values expressed in ml/min/100 g, the highest in fl, the lowest in white; CBF is decreased in the posterior and central right hemisphere whereas it is normal in the left according to age.
		Scale represents the CBF values expressed in ml/min/100 g, the highest in fl, the lowest in white; CBF is increased in the posterior left hemisphere whereas it is normal in the right according to age.
	jnnp.bmjjournals.com /cgi/content/full/63/5/616 (2712 words)

	Positron Emission Tomography Information on Healthline
		Positron emission tomography (PET) is a highly specialized imaging technique using short-lived radiolabeled substances to produce powerful images of the body's biological function.
		As positrons emitted from the radionuclides encounter electrons in the body, they produce high-energy photons (gamma rays) that can be recorded as a signal by detectors surrounding the body.
		PET images thus show the chemical functioning of an organ or tissue, unlike x ray, computed tomography, or magnetic resonance imaging, which show only body structure.
	www.healthline.com /galecontent/positron-emission-tomography (927 words)

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