
	Where results make sense

Topic: Sinigrin

	Metabolism of sinigrin (2-propenyl glucosinolate) by the human colonic microflora in a dynamic in vitro ...
		for 9.6 to 30.4% of sinigrin degradation (19.0% ± 8.6%).
		Kinetics of sinigrin degradation (squares) and AITC (closed circles) in the lumen and the cumulative amount of AITC (open circles) in the dialysis fluid in the dynamic in vitro large-intestinal model harbouring an individual human microflora of four volunteers (A–D), after the addition of 12 mM sinigrin.
		Sinigrin content of the Brussels sprouts was such that the total amount of sinigrin added after 14 h was ~118 µmol.
	carcin.oxfordjournals.org /cgi/content/full/23/6/1009 (5847 words)

	Uptake and distribution of sinigrin in microspore derived embryos of Brassica napus L (Site not responding. Last check: 2007-11-02)
		Uptake and distribution of sinigrin in microspore derived embryos of Brassica napus L
		Uptake and distribution of sinigrin in microspore derived embryos of Brassica napus L. J Plant Physiol.
		Following excess feeding of sinigrin, we found a strong uptake against a concentration gradient and stable accumulation by the embryos.
	www.sproutnet.com /Nutrition/Research/uptake_and_distribution_of_sinig.htm (214 words)

	GLUCOSIDE - LoveToKnow Article on GLUCOSIDE
		The name was originally given to vegetable products of this nature, in which the other part of the molecule was, in the greater number of cases, an aromatic aldehydic or phenolic compound (exceptions are sinigrin and jalapin or scammonin).
		Ethylene Derivatives.These are generally mustard oils, and are characterized by a burning taste; their principal occurrence is in mustard and Tropaeolum seeds.
		Sinigrin or the potassium salt of inyronic acid, C10Hi6NS2KO9~H2O, occurs in fl pepper and in horse-radish root.
	www.1911encyclopedia.org /G/GL/GLUCOSIDE.htm (1144 words)

	BoDD (Botanical Dermatology Database) - CRUCIFERAE
		Sinigrin and glucotropaeolin have been reported to be the principal glucosinolates of A.
		Kjaer (1960) reported the detection of sinigrin in the seeds of this species, but Cole (1976) found that sec-butyl isothiocyanate is released from the plant on autolysis of its glucosinolates.
		Sinigrin, an alkenyl glucosinolate, appears to be the principal compound.
	bodd.cf.ac.uk /BotDermFolder/BotDermC/CRUC.html (5558 words)

	Uptake and distribution of sinigrin in microspore derived embryos of Brassica napus L (Site not responding. Last check: 2007-11-02)
		Uptake and distribution of sinigrin in microspore derived embryos of Brassica napus L. J Plant Physiol.
		The sinigrin in the culture medium was almost completely absorbed by the embryos after three days of culture.
		Following excess feeding of sinigrin, we found a strong uptake against a concentration gradient and stable accumulation by the embryos.
	sproutnet.com /Nutrition/Research/uptake_and_distribution_of_sinig.htm (214 words)

	New Chapter - Research
		Although both sulforaphane and sinigrin are isothiocyanates, their action in the body differs somewhat.
		Moreover, it is imperative to remember that isothiocyanates, such as sulforaphane and sinigrin, are just two members in a whole family of glucosinolate compounds.
		Degradation of sinigrin by Lactobacillus agillis strain R 16.
	www.new-chapter.com /research/broccoli.html (2138 words)

	Sinigrin Records \| Sinigrin Records - Home of Saucer and some of the best Toronto Indie Rock
		Sinigrin Records - Home of Saucer and some of the best Toronto Indie Rock
		Sinigrin is an independent music label based out of Toronto, Ontario Canada.
		Sinigrin Records is proudly powered by Drupal and valid XHTML and CSS.
	www.sinigrin.com (261 words)

	ESA 2004 (Site not responding. Last check: 2007-11-02)
		One generation of selection was undertaken to produce families with high or low levels of a structural (trichomes) and a chemical (sinigrin) defense, in all four combinations.
		Sinigrin concentration and trichome density had strong negative effects on early season generalist herbivory, and sinigrin also increased seedling survival.
		Increased sinigrin concentrations were selected for in the generalist present treatments, but selected against in the specialist only treatment.
	abstracts.co.allenpress.com /pweb/esa2004/document?ID=35731 (270 words)

	30
		juncea germplasm was characterized by the predominance of sinigrin and gluconapin.
		Sinigrin concentration varied from 50% to 90% of the total glucosinolates depending on the region where the accessions were collected.
		Progoitrin, sinigrin, gluconapoleiferin, glucobrassicin, neoglucobrassicin, glucotropaeolin and gluconasturtin were the minor ones.
	www.regional.org.au /au/gcirc/4/30.htm (1271 words)

	617
		The glucosinolate sinigrin was purchased from Sigma, progoitrin, gluconapin and sinalbin were isolated and purified from rapeseed tissue by solvent extraction followed by RP-HPLC according to a slightly modified protocal from Bjorkqvist (1988).
		In vitro degradation of sinigrin by phytopathogenic fungi of Brassica
		But increasing sinigrin levels in the liquid culture added 2% D-glucose had no significant effects on fungal growth, sinigrin content assay showed that no degradation was found in the liquid media with 2% D-glucose.
	www.regional.org.au /au/gcirc/3/617.htm (1166 words)

	Medline Publication: Effects of dietary sinigrin or indole-3-carbinol on O6-methylguanine-DNA-transmethylase activity ...
		Effects of dietary sinigrin or indole-3-carbinol on O6-methylguanine-DNA-transmethylase activity and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced DNA methylation and tumorigenicity in F344 rats.
		The effects of dietary sinigrin and indole-3-carbinol (I3C) on DNA methylation and O6-methylguanine--DNA-transmethylase activity, factors which may be of importance in the induction of tumorigenicity by the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), were investigated.
		These results suggested that dietary sinigrin might reduce the incidence of NNK-induced hepatic tumors with no effect on NNK tumorigenesis of the lung and nasal cavity, whereas I3C might increase hepatic tumor incidence and reduce NNK tumorigenesis of the lung and nasal cavity.
	www.fred.psu.edu /ds/retrieve/fred/medlinepub/3168166 (329 words)

	Education \| Be of good cheer
		Sinigrin should be scary as it breaks down to form an insect-killing chemical weapon in the plant.
		For humans, though, there is only one nasty side-effect, because this breakdown product is responsible for the sprout's pungency - both on the stem and after the meal.
		The IFR researchers, however, have found that sinigrin is more than a party pooper.
	education.guardian.co.uk /print/0,3858,4569991-110865,00.html (704 words)

	IFR Information Sheet - why your best friend could be a brassica (Site not responding. Last check: 2007-11-02)
		The breakdown product of sinigrin, allyl isothiocyanate, responsible for the characteristic smell of sprouts, is the active ingredient.
		It works by persuading the pre-cancerous cells to commit suicide - a natural process called apoptosis - and so powerful is the effect that we think that the occasional meal of sprouts could destroy these cells in the colon.
		There is an upper limit too; if levels of sinigrin in the plant rise above 200 milligrams per 100 grams of fresh vegetable, the sprouts become so bitter no-one will eat them.
	www.ifrn.bbsrc.ac.uk /public/FoodInfoSheets/brassicas.html (620 words)

	Myrosinase Activity in Soil -- Al-Turki and Dick 67 (1): 139 -- Soil Science Society of America Journal
		of glucose released upon enzymatic hydrolysis of sinigrin.
		sinigrin for all soils used in this study.
		is equivalent to 8.3 mg of sinigrin per milliliter of soil solution.
	soil.scijournals.org /cgi/content/full/67/1/139 (3140 words)

	Brassica vegetables (Site not responding. Last check: 2007-11-02)
		AITC is the result of the breakdown of a chemical compound called Sinigrin.
		Sinigrin is found in mustard, cabbage, horseradish, cauliflower, Brussels sprouts, swede, kale and wasabi.
		We have also known for many years that sinigrin breakdown products kill cancer cells.
	www.alternativehealingtools.com /articles/vegtibles.htm (274 words)

	Real Wasabi (Site not responding. Last check: 2007-11-02)
		A member of the brassicae family, Wasabia Japonica owes both its pungency and healthful benefits to a suite of isothiocyanates that occur due to enzymatic activation when the plant tissues are crushed during grating.
		Two glucosinolates, sinigrin and glucocochlearin are especially important in wasabi.
		While both are essentially tasteless compounds on their own, when exposed to the myrosinase enzyme (also present in wasabi in separate plant cells), hydrolosis transmutes these sulfur compounds into pungent allyl isothiocyanate (CH2=CH-CH2-NCS) and sec-butyl isothiocyanate (CH3-CH2-CH(CH3)-NCS), respectively.
	www.realwasabi.com /Science (199 words)

	Hydrolysis of Glucosinolates to Isothiocyanates after Ingestion of Raw or Microwaved Cabbage by Human Volunteers -- ... (Site not responding. Last check: 2007-11-02)
		Scheme showing hydrolysis of sinigrin under the action of myrosinase and factors that may influence the outcome of hydrolysis.
		Elfoul L., Rabot S., Khelifa N., Quinsac A., Duguay A., Rimbault A. Formation of allyl isothiocyanate from sinigrin in the digestive tract of rats mono-associated with a human colonic strain of Bacteroides thetaiotaomicron.
		Combourieu B., Elfoul L., Delort A. M., Rabot S. Identification of new derivatives of sinigrin and glucotropaeolin produced by the human digestive microflora using H-1 NMR spectroscopy analysis of in vitro incubations.
	cebp.aacrjournals.org /cgi/content/full/13/1/125 (4305 words)

	Sinigrin monohydrate - CAS 3952-98-5 - Catalog of Chemical Suppliers (Site not responding. Last check: 2007-11-02)
		Sinigrin monohydrate - CAS 3952-98-5 - Catalog of Chemical Suppliers
		Visit our website to find more information like MSDS, infra-red (IR), molfile, sdf file, structure, price, a catalog of over 130000 chemicals and over 150 chemical suppliers.
		You may also add your own catalog of chemicals for free.
	www.chemexper.com /chemicals/supplier/cas/3952-98-5.html (48 words)

	ESA 2004 (Site not responding. Last check: 2007-11-02)
		Our previous work has analyzed the differences in sinigrin content in young leaves of Alliaria petiolata in native and invasive populations and found significantly higher concentrations of sinigrin in leaves from the invasive populations in some cases.
		However, these differences in sinigrin content were strongly correlated with plant size, which is dependent on resource availability, and also appear to be variable depending on year and plant life stage.
		We tested whether ecotypic or genetic differentiation for sinigrin content and growth is detectable in common environments using two common garden experiments, one in the native range (Switzerland) and one in the invasive range (Massachusetts).
	abstracts.co.allenpress.com /pweb/esa2004/document?ID=37032 (273 words)

	[No title]
		Amazingly after 3 days sprouting, the compound Sulforaphane is between 10-100 times more concentrated in sprouting seed than in the mature vegetable - and it s a powerful blocking agent against cancer.
		Broccoli sprouts also contain Sinigrin which persuades the pre-cancerous cells to commit suicide.
		It is believed it has so powerful an effect that the occasional meal of young broccoli sprouts may destroy cancerous cells in the colon.
	seeds.thompson-morgan.com /us/en/product/25/2?SA=1113;set-country=us (351 words)

	Protein - God-Perid Assay (Site not responding. Last check: 2007-11-02)
		The God-Perid test is a clinical test for determining blood sugar level (Werner et al., 1970), where released glucose is measured.
		Myrosinase hydrolyzes the substrate sinigrin (2-propenylglucosinolate) (Sigma) and releases glucose.
		To measure the amount of glucose released, God-Perid reagent from Boehringer Mannheim, GMBH is used.
	boneslab.chembio.ntnu.no /godperid.htm (219 words)

	Western Ag Innovations - Szmigielska and Schoenau, 2000
		A new one-step extraction using anion-exchange membranes for the HPLC determination of glucosinolates in mustard seeds is reported.
		The exchange of glucosinolates on the membranes was studied using sinigrin in solutions and sinigrin added as an internal standard to seeds of yellow mustard.
		Using this procedure, the sinigrin extraction from solutions and from mustard seeds was linear with 80% recovery.
	www.westernag.ca /innov/Papers/SzmigielskaandSchoenau2000.html (284 words)

	Search Results for- Sinigrin Monohydrate: Sinigrin monohydrate - Cole-Parmer Catalog
		We have access to suppliers full lines— for products beyond what you see here.
		Sinigrin monohydrate and other Shikimi to Soda products are now available to order from the Cole Parmer Instrument Catalog.
		Click any Sinigrin monohydrate category to view all models and products.
	www.coleparmer.com /catalog/product_index.asp?cls=38102 (66 words)

	link100
		Instead of creating an artificial diet for their insects, they introduced a plant allelochemical into a plant that is part of the butterflies' natural diet.
		The larvae fed, and their growth was markedly inhibited.
		Celery containing a level of sinigrin equivalent to the level found in cruciferous vegetation was lethal to all the tested larvae.
	www.uky.edu /~garose/link100.htm (4285 words)

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