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Topic: Skeletal muscle relaxant

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	AANOS, Professor Kazem Fathie on Musculoskeletal Disorders
		The degree of muscle stiffness and skeletal muscle spasm was assessed by interview, inspection, palpation and estimation of the range of motion.
		Muscle spasm was identified as sudden, violent, involuntary contractions of a muscle or muscle group attended by pain and interference with proper function.
		A skeletal muscle relaxant, metaxalone, was dispensed to 50 patients with skeletal muscle disorders, treated on an outpatient basis at the Medical College of Virginia.
	www.aanos.org /edctn_msk_disordr.htm (1577 words)

	Muscle relaxant - Wikipedia, the free encyclopedia
		A muscle relaxant is a drug which decreases the tone of a muscle.
		There are several other skeletal muscle relaxants, which may belong in the above categories:
		Drugs from classes other than the muscle relaxant class are also used to treat spasticity:
	en.wikipedia.org /wiki/Muscle_relaxant (117 words)

	AANOS, Article by Professor Fathie
		Beckman(1), in his chapter on Skeletal Muscle Relaxants, reported that the clinical improvement in patients with muscular disorders is due to an intrinsic relaxant effect on skeletal musculature and pointed out that certain drugs used primarily for their tranquilizing properties are also helpful in the management of certain neurologic disorders with a marked muscular component.
		The skeletal muscle relaxant used in the present studies was metaxalone, a relatively new skeletal muscle relaxant.
		Although the relaxant properties of such drugs may not be as great as the relaxant properties of other drugs, the patients may be willing to overlook their lesser effect on spasticity because of the enhanced feeling of well-being induced by their sedative-tranquilizing properties.
	www.aanos.org /edctn_msk_disordr_double_blind_study.htm (2392 words)

	Skeletal muscle relaxant effect of Chonemorpha macrophylla in experimental animals Roy Ranendra Kumar, Ray NM, Das AK - ... (Site not responding. Last check: 2007-10-23)
		MATERIALS AND METHOD: The skeletal muscle relaxant effect of the alcoholic extract of CM was studied on isolated frog rectus abdominis muscle, isolated rat phrenic nerve diaphragm muscle preparation and in intact young chicks.
		The parameter studied in the isolated muscle or isolated nerve muscle preparations was the extent of inhibition of acetylcholine or electrically-induced contraction of skeletal muscles.
		The type of skeletal muscle relaxation produced by CM was studied in unanaesthetized intact young chicks by the method of Battle and Zaimis.
	www.ijp-online.com /article.asp?issn=0253-7613;year=2005;volume=37;issue=2;spage=116;epage=119;aulast=Roy (1743 words)

	Muscle Relaxer. Pain Relief from US Pharmacy. Without Prescription and no Delay.
		Skelaxin is a muscle relaxant used to treat the pain and stiffness of muscle injury, strain, sprain and spasm.
		Soma is a muscle relaxant used to relieve the pain and stiffness of muscle spasms and discomfort due to strain and sprain.
		Dantrolene (Dantrium®) is a peripherally acting skeletal muscle relaxant that produces its effect by interfering with the release of calcium from the sarcoplasmic reticulum.
	www.readingtarget.com /shop/muscle.htm (1906 words)

	MedlinePlus Drug Information: Skeletal Muscle Relaxants (Systemic) (Site not responding. Last check: 2007-10-23)
		Skeletal muscle relaxants are used to relax certain muscles in your body and relieve the stiffness, pain, and discomfort caused by strains, sprains, or other injury to your muscles.
		Pregnancy—Although skeletal muscle relaxants have not been shown to cause birth defects or other problems, studies on birth defects have not been done in pregnant women.
		Skeletal muscle relaxants may cause blurred vision or clumsiness or unsteadiness in some people.
	www.nlm.nih.gov /medlineplus/druginfo/uspdi/202523.html (1706 words)

	[No title] (Site not responding. Last check: 2007-10-23)
		Muscle relaxants are indicated primarily for the treatment of painful musculo-skeletal...
		Flexeril is a muscle relaxant, used to treat the pain and stiffness of mu...
		Flexeril is a muscle relaxant prescribed to relieve muscle spasms resulting from injuries such as sprains,...
	members.lycos.co.uk /lolipoper/flexerilmusclerelaxant.html (600 words)

	[No title]
		Animal studies indicate that cyclobenzaprine does not act at the neuromuscular junction or directly on skeletal muscle.
		The clinical responses include improvement in muscle spasm as determined by palpation, reduction in local pain and tenderness, increased range of motion, and less restriction in activities of daily living.
		Muscle spasm, local pain and tenderness, limitation of motion, and restriction in activities of daily living were evaluated.
	www.best-meds.com /druginfo/flexeril_clinical.htm (557 words)

	Dantrolene
		Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber.
		Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
		They have their primary clinical and therapeutic uses in the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck.
	www.dentalarticles.com /drugs/96.php (335 words)

	Skelaxin - prescription muscle relaxant
		Skelaxin is a skeletal muscle relaxant used to relieve the pain of muscle injuries, spasms, sprains, and strains.
		Benzodiazepines (a class of antidepressants, anti-panic agents, and muscle relaxants) such as Ativan (lorazepam), Valium (diazepam), Halcion (triazolam), Restoril (temazepam), Librium (chlordiazepoxide), Xanax (alprazolam), Tranxene-SD (clorazepate), Paxipam (halazepam), ProSom (estazolam), Klonopin (clonazepam), and others, should be used cautiously with metaxalone.
		Skeletal muscle relaxants of any other type, such as Soma (carisoprodol), Robaxin (methocarbamol), or Flexeril (cyclobenzaprine) may overly depress the central nervous system when combined.
	www.accessmednet.com /prescription-drug-information/skelaxin-.html (1038 words)

	Data Sheet
		Studies have shown that in the presence of dantrolene sodium, the responses of the muscle to caffeine are decreased or delayed.
		In isolated muscle preparations, dantrolene sodium uncouples the excitation and contraction of skeletal muscle, probably by interfering with the release of calcium from the sarcoplasmic reticulum.
		Dantrolene sodium may prevent the increase in myoplasmic calcium and the acute catabolism within the muscle cell by interfering with the release of calcium from the sarcoplasmic reticulum to the myoplasm.
	www.medsafe.govt.nz /Profs/Datasheet/d/DantriumIVinj.htm (1811 words)

	Diazepam (Site not responding. Last check: 2007-10-23)
		Diazepam is used orally for the short-term management of anxiety disorders and acute alcohol withdrawal, and as a skeletal muscle relaxant.
		Parenterally, it is indicated as an antianxiety agent, sedative, amnestic, anticonvulsant, skeletal muscle relaxant, anesthetic adjunct, and as a treatment for alcohol withdrawal.
		Anticonvulsant, skeletal muscle relaxant, and anxiolytic effects are usually evident after the first dose.
	homepage.mac.com /cwasson/Contents/7.1.htm (1042 words)

	Skeletal Muscle Relaxants (Systemic)
		Tell your doctor if you have ever had any unusual or allergic reaction to any of the skeletal muscle relaxants or to carbromal, mebutamate, meprobamate (e.g., Equanil), or tybamate.
		Although skeletal muscle relaxants have not been shown to cause birth defects or other problems, studies on birth defects have not been done in pregnant women.
		Studies with the skeletal muscle relaxants have been done only in adult patients, and there is no specific information comparing use of these medicines in children with use in other age groups.
	allnutritionals.com /drugs/s/skeletalmusclerelaxants-systemic.shtml (1643 words)

	Skelaxin Drug Information
		Pregnancy-Although skeletal muscle relaxants have not been shown to cause birth defects or other problems, studies on birth defects have not been done in pregnant women.
		Children-Studies with the skeletal muscle relaxants have been done only in adult patients, and there is no specific information comparing use of these medicines in children with use in other age groups.
		Porphyria-Depending on which of the skeletal muscle relaxants you take, the chance of side effects may be increased; your doctor can choose a muscle relaxant that is less likely to cause problems
	www.drugs.com /cons/Skelaxin.html (1953 words)

	Muscle Relaxant, Muscle Relaxer, Natural Muscle Relaxant, Treatment For Leg Cramp, Skeletal Muscle Relaxant
		Leg Cramps, Muscle Cramps aching sore muscles nighttime leg cramps.
		What causes leg cramps can be from a number of sources but what can relieve cramping, aching muscles is Valerin®.
		Valerin® the All Natural Leg Cramp, Muscle Cramp, Stress and Tension relief product is Manufactured in our own state-of-the-art FDA Registered Facility using Good Manufacturing Practices (GMPs) assuring correct potencies, freshness, quality and purity.
	www.wonderlabs.com /muscle-cramps/index.html (292 words)

	Cyclobenzaprine Review Cyclobenzaprine Pharmacy (Site not responding. Last check: 2007-10-23)
		cyclo benzaprine hcl is a muscle relaxant used to treat muscle spasms.
		cyclo benzaprine hydrochloride is a prescription medication that relaxes muscles and relieves pain and discomfort associated with strains, sprains, spasms or other muscle injuries.
		It relieves muscle spasms of local origin but is not effective in spasms which originat e from diseases in the brain or spinal cord.
	www.ray-spot.com /widjd.htm (504 words)

	Spasticity Treatment (Site not responding. Last check: 2007-10-23)
		Decreases muscle contraction by changing the amount of calcium within the muscle cells.
		In some cases, surgery may be performed on the bones (orthopedic surgery) to correct deformities, caused by prolonged spasm, and/or surgery to the nerves (rhizotomy) to reduce spasticity.
		It is important to maintain strength and control of muscle movement, as well as to regain, or maintain self-care and mobility.
	www.diseases-explained.com /Spasticity/spastreatment.html (233 words)

	August 98
		Tizanidine, a clonidine derivative, is a centrally acting skeletal muscle relaxant with alpha-2 adrenergic activity.
		This drug is indicated for the acute and intermittent management of increased muscle tone associated with spasticity.
		In comparative trials of tizanidine, baclofen and diazepam, muscle tone was decreased to a similar extent in patients with spasticity from multiple causes.
	www2.kumc.edu /druginfo/pharmkey/pharmkey8-98.html (1720 words)

	Skelaxin - Muscle Relaxant Institute - Skelaxin
		Skelaxin® (metaxalone) is a centrally acting skeletal muscle relaxant.
		It does not act directly on striated muscle; therefore, muscle relaxation may be due to its sedative properties.
		It is indicated as adjunct therapy to rest, physical therapy and other measures to relieve the discomforts of acute, painful musculoskeletal disorders.
	www.muscle-relaxant-institute.com /skelaxin.html (628 words)

	Soma Drug Information Soma Rx (Site not responding. Last check: 2007-10-23)
		you have ever had an allergic reaction to so ma or another skeletal muscle relaxant, be sure to inform...
		Soma, a muscle relaxant, is used with rest, physical therapy, and other measures to relax muscles and relieve pain and discomfort caused by strains, sprains, and other muscle injuries.
		so ma is a muscle relaxant that relieves pain and stiffness in your muscles and joints.
	www.klm-finder.com /wfeia.htm (530 words)

	JAMA -- Abstract: Evaluation of a muscle relaxant: dantrolene sodium (Dantrium), February 24, 1975, Dykes 231 (8): 862
		JAMA -- Abstract: Evaluation of a muscle relaxant: dantrolene sodium (Dantrium), February 24, 1975, Dykes 231 (8): 862
		Evaluation of a muscle relaxant: dantrolene sodium (Dantrium)
		with skeletal muscle spasticity who are in a stable neurological state.
	jama.ama-assn.org /cgi/content/abstract/231/8/862 (137 words)

	ORPHENADRINE - INJECTION (Flexor, Norflex, Orphenate) side effects, medical uses, and drug interactions.
		USES: This medication is a skeletal muscle relaxant used to relieve pain and discomfort associated with musculoskeletal injuries and conditions.
		Muscle Cramps - Learn medical information related to muscle cramps; giving description, causes, treatment, and prevention of this extremely common condition.
		Muscle Pain (Myofascial Pain Syndrome) - Muscle pain, or myofacial pain is a chronic condition affecting the connective tissue that covers the muscle (fascia).
	www.medicinenet.com /orphenadrine-injection/article.htm (481 words)

	Review Cyclobenzaprine Hcl - Muscle Relaxant For Muscle Spasms
		Cyclobenzaprine HCL is a muscle relaxant used to treat muscle spasms.
		Cyclobenzaprine HCL - muscle relaxant relieves muscle spasms of local origin but is not effective in spasms which originate from diseases in the brain or spinal cord.
		lobenzaprine HCL - muscle relaxant relieves muscle spasms of local origin but is not effective in spasms which originate from diseases in the brain or spinal cord.
	www.fitness-queen.biz /z5cycl.htm (477 words)

	GENERIC SOMA :: Cheap Generic Soma (Site not responding. Last check: 2007-10-23)
		2002, when it figured into at least 7,919 U.S. cheap generic soma admissions, according to the desired skeletal muscle relaxant prescribed cheap generic soma medicinal purposes, but it is frequently abused and is cheap generic soma commonly prescribed, noncontrolled, skeletal muscle relaxant whose active metabolite cheap generic soma meprobamate.
		In animals, carisoprodol produces muscle relaxation cheap generic soma blocking interneuronal activity and depressing transmission of polysynaptic neurons cheap generic soma the eyes, temporary loss of balance and coordination, impairment cheap generic soma visual accommodation, tachycardia, nausea, vomiting, ataxia, tremor, sleep disturbances.
		Many subjects were involved in accidents, and cheap generic soma muscle relaxants can contribute to impairment.
	1apowerwheelchairs.com /medmaster/cheap-generic-soma.html (1268 words)

	WE MOVE - Hereditary Spastic Paraplegia - Treatment
		Although no treatment is currently available that may slow or alter the disease's progression, therapy with baclofen (Lioresal®), a voluntary (i.e., skeletal) muscle relaxant, may help to reduce spasticity in some HSP patients.
		In addition, in patients with bladder control problems, treatment with oxybutynin (Ditropan®), an involuntary (i.e., smooth) muscle relaxant and spasmolytic agent, may help to relieve spasticity of the bladder.
		Although physical therapy does not prevent or reduce degenerative changes of the spinal cord, experts indicate that receiving regular therapy may play an important role in helping HSP patients maintain and increase muscle strength and range of motion.
	www.wemove.org /hsp/hsp_tre.html (314 words)

	Parkinsn's List Drug DataBase diazepam / Valium,Valrelease,Dizac
		In addition to treating status epilepticus, diazepam has recently been shown effective in preventing recurrence of febrile seizures.I Although diazepam has been the benzodiazepine of choice for status epilepticus, recent evidence indicates that lorazepam may be more beneficial because it provides longer control of seizures and produces less cardiorespiratory depression.
		The antianxiety action of benzodiazepines may be a result of their ability to block cortical and limbic arousal following stimulation of the reticular pathways while muscle relaxation properties are mediated by inhibiting both mono-and polysynaptic pathways.
		It also can help patients cope with alcohol withdrawal, relax muscles, and treat certain types of seizures (convulsions).
	www.parkinsons-information-exchange-network-online.com /drugdb/045.html (2352 words)

	MDVU Resource Library - Hereditary Spastic Paraplegia - Treatment
		Baclofen may be administered by mouth (orally) or delivered directly to the spinal canal (intrathecally).
		Therapy with another skeletal muscle relaxant, dantrolene (Dantrium®), may also improve spasticity in some patients.
		In some patients with slowly progressive disease, neuro-orthopedic surgery to lengthen the ankle plantar flexors or hip adductors may be appropriate.
	www.mdvu.org /library/disease/hsp/hsp_tre.html (315 words)

	Cyclobenzaprine - Generic Flexeril:Muscle Relaxant (Site not responding. Last check: 2007-10-23)
		Cyclobenzaprine (generic Flexeril) relaxes muscles and relieves pain and discomfort associated with strains, sprains, spasms or other muscle injuries.
		It has been shown to relieve localized muscle spasms but is not recommended for spasms which originate from diseases in the spinal cord or brain.
		Inform your physician if you develop any of the following symptoms: muscle stiffness, skin rash, itching, rapid heart rate, swelling of the face, difficulty urinating.
	www.lowestcostrx.com /products.asp?id=95 (564 words)

	[No title] (Site not responding. Last check: 2007-10-23)
		Flexeril(should be used only for short periods (up to two or three weeks) because adequate evidence of effectiveness for more prolonged use is not available and because muscle spasm associated with acute, painful musculoskeletal conditions is generally of short duration and specific therapy for longer periods is seldom warranted.
		Animal studies show that cyclobenzaprine acts primarily within the central nervous system at brain stem as opposed to spinal cord levels, although it action on the latter may contribute to its overall skeletal muscle relaxant activity.
		There does not appear to be any conclusive evidence that any of the skeletal muscle relaxants are superior to the others.
	www.heritage-info.com /mocaidrx/files/drug_monographs/06-03/Flexerilmon.doc (1237 words)

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