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Topic: Sodium bisulfite


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In the News (Tue 14 Feb 12)

  
  567. Sulfur dioxide and sulfites (WHO Food Additives Series 18)
Sodium bisulfite was not mutagenic in the host-mediated assay in mice, the dominant lethal assay in rats, or the in vivo cytogenic assay in rats at doses up to 150 mg/kg; it showed no mutagenic activity on human tissue culture cells in vitro at levels up to 200 µg/ml (Anon., 1972b).
For sodium bisulfite (Anon., 1972a) the doses in mg/kg bw in mice, rats and hamsters were up to 150, 110 and 120 respectively; for sodium metabisulfite (Anon., 1972a) in mice, rats and hamsters up to 160, 110 and 120 respectively; for potassium metabisulfite (Anon., 1975a) in mice and rats up to 125 and 155 respectively.
Sodium bisulfite was given to two dogs by the same method and for the same length of time as in the preceding experiment in daily doses of 1.08-2.51 g.
www.inchem.org /documents/jecfa/jecmono/v18je14.htm   (7945 words)

  
 Treatment of arthritis with bisulfite - Patent 4462988
Sodium bisulfite (usually shown by formula to be NaHSO.sub.3) has heretofore been used for many commercial purposes, such as a preservative for prevention of the deterioration of liquids, such as food stuffs and pharmaceutical solids and solutions, and has been used medically externally for parasitic skin diseases and internally as a gastrointestinal antiseptic.
The sodium bisulfite of commerce consists chiefly of sodium metabisulfite, Na.sub.2 S.sub.2 O.sub.5, and for purposes of this invention such is believed to possess the same properties as (and to be equivalent to) the true sodium bisulfite when dissolved in an aqueous solution.
It has now been discovered that sodium bisulfite is useful in low doses and over extended periods in the treatment of the symptoms of arthritis and arthritic conditions when administered to humans in an aqueous dilute solution.
www.freepatentsonline.com /4462988.html   (2195 words)

  
 [No title]   (Site not responding. Last check: 2007-10-10)
In general, the extracted DNA is further modified by sodium bisulfite and then subjected to a method of promoter methylation analysis that involves the use of bisulfite-modified DNA.
Sodium bisulfite treatment converts all unmethylated cytosines in the DNA to uracil by deamination, but leaves the methylated cytosine residues intact.
CpG retrieval, however, differs from antigen retrieval in that CpG retrieval recovers the cytosines that are otherwise unmodifiable by sodium bisulfite, as opposed to antigen retrieval that retrieves protein antigen that are otherwise undetectable by antibody due to formalin-induced cross-links.
www.wipo.int /cgi-pct/guest/getbykey5?KEY=03/83107.031009&ELEMENT_SET=DECL   (3962 words)

  
 Toxicologic Review of Selected Chemicals   (Site not responding. Last check: 2007-10-10)
Sodium bisulfite is a white crystalline powder and has an odor like that of sulfur dioxide.
The ACGIH reports that sodium bisulfite is an eye, skin, and mucous membrane irritant; acute exposures have resulted in mild eye and respiratory effects (ACGIH 1986/Ex.
Although cases of severe, and even lethal, allergic reactions to this material have been documented from the use of sodium bisulfite as a food additive, OSHA does not believe that there is sufficient information to use as a basis for an exposure limit to protect against inhalation-induced allergic reactions.
www.cdc.gov /niosh/pel88/7631-90.html   (403 words)

  
 Photographic chemistry notes by Ryuji Suzuki   (Site not responding. Last check: 2007-10-10)
Robert Smith of U.S. Borax explains that "sodium metaborate tetrahydrate is the stable solid phase in contact with its saturated solution between 11.5 and 53.6°C." Therefore, octahydrate in old nomenclature and tetrahydrate in modern nomenclature indicate the identical chemical in the same hydration form.
Pure sodium bisulfite is rarely traded for industrial or photographic purposes in dry form, because pure dry form is unstable.
Commercially dry sodium bisulphite of satisfactory quality is now obtainaboe and may be used in mixing formulas calling for either the metabisulphite or the bisulphite.
silvergrain.org /Photo-Tech/chemistry-misnomers.html   (960 words)

  
 MethPrimer Help
Bisulfite sequencing PCR (BSP): DNA is first modified with sodium bisulfite, and subsequently amplified by PCR using primers that are specific for modified DNA but do not contain any CpG sites in their sequence.
Bisulfite restriction PCR: DNA is first modified with sodium bisulfite, and subsequently amplified by PCR using primers that are specific for modified DNA but do not contain any CpG sites in their sequence.  The resulting PCR product is digested with methylation sensitive restriction enzymes.
Methylation-Specific PCR (MSP): DNA is first modified with sodium bisulfite, and subsequently amplified by PCR using two pairs of primers, with one pair specific for methylated DNA; the other unmethylated DNA.
www.urogene.org /methprimer/help.html   (508 words)

  
 [No title]   (Site not responding. Last check: 2007-10-10)
In its general reactions, sodium metabisulfite (like sulfites and hydrogen sulfites) is a moderately strong reducing agent which yields sulfate upon reaction with oxidizing agents.
Sodium bisulfite reacts with epoxides, cyclic imines and episulfides, by ring cleavage and formation of the corresponding sulfonate.
Sodium metabisulfite and sodium bisulfite solution can be readily oxidized and many of their industrial applications are based on their reducing properties.
www.genchemcorp.com /products/sodmetabi.shtml   (431 words)

  
 Bleaching Lumber   (Site not responding. Last check: 2007-10-10)
Sodium bisulfite is an old name for sodium hydrogen sulfite -- the "bi" in the older literature standing for "hydrogen".
I'm a bit confused by your equating this substance with "laundry bleach" which is typically sodium hypochlorite (an oxidizing agent, as is potassium permanganate).
You could also use sodium sulfite, which is a chemical used in swimming pools to lower the level of "chlorine" when the pool is "shocked" to kill off an algae growth.
www.newton.dep.anl.gov /askasci/chem00/chem00675.htm   (253 words)

  
 SODIUM BISULFITE
Sodium Metabisulfite [7681-57-4]: No LD50/LC50 information found relating to normal routes of occupational exposure.
Investigated as a tumorigen, mutagen and reproductive effector.
Sodium Bisulfite [7631-90-5]: Oral rat LD50: 2000 mg/kg.
www.jtbaker.com /msds/englishhtml/s3074.htm   (1105 words)

  
 Section 6 - Wastewater Treatment, 6.2 CONVENTIONAL TREATMENT TECHNOLOGIES
Sulfur dioxide gas usage is restricted mostly to large treatment plants and sodium bisulfite is used at most small and medium-sized systems, but it is also used at large systems.
The theoretical quantity of sodium bisulfite or sulfur dioxide required to reduce one pound of hexavalent chromium is approximately 3 lbs and 2 lbs, respectively.
Sodium hydrosulfite is also used by one respondent as a chromium reducing agent in an alkaline environment (PS 173 and PS 253).
www.nmfrc.org /bluebook/sec622.htm   (1231 words)

  
 [No title]   (Site not responding. Last check: 2007-10-10)
Oxygen scavengers that can be used in the practice of this invention include many of the materials that have been used or disclosed for use as oxygen scavengers in such applications as boiler operations where they are included for purposes of reducing corrosion.
Oxygen scavengers of particular interest in the present application are sodium sulfite, sodium bisulfite, sodium thiosulfate, sodium lignosulfate, and ammonium bisulfite, and of these, sodium sulfite and sodium bisulfite are the most preferred.
A method in accordance with claim 1 in which said oxygen scavenger is a member selected from the group consisting of sodium sulfite, sodium bisulfite, sodium thiosulfate, sodium lignosulfate, and ammonium bisulfite.
www.wipo.int /cgi-pct/guest/getbykey5?KEY=03/72616.030904&ELEMENT_SET=DECL   (1748 words)

  
 City of Mankato: Wastewater Treatment
odium bisulfite is injected into the effluent water to bind with the remaining chlorine from the disinfection process.
The 6000-gallon sodium bisulfite tank is located in the influent pumping station.
Target sodium hypochlorite and sodium bisulfite rates are set by the operations staff and maintained through a system of automatic analyzers.
www.ci.mankato.mn.us /utility/wwp09-12.php3   (244 words)

  
 Processes for the preparation of bis-benzoins and bis-benzils - Patent 4024067
The sodium cyanide or potassium cyanide, preferably dissolved in water, is slowly added to the reaction mixture.
To a stirred suspension of terephthalaldehyde-bid-sodium bisulfite adduct (10.0 g, 0.0292 mol) in water (30 ml), cooled in an ice bath, was added a solution of potassium cyanide (2.96 g, 0.0584 mol) in water (15 ml) over a period of 27 min.
EXAMPLE II The terephthalaldehyde cyanohydrin was prepared (in a manner analogous to that as described for Example I) in two batches each using 42.8 g (0.1451 mol) of sodium bisulfite adduct, 17.0 g (0.2611 mol) of potassium cyanide and 320 ml of water.
www.freepatentsonline.com /4024067.html   (1417 words)

  
 Process - Liquids - Disinfection   (Site not responding. Last check: 2007-10-10)
The process involves injecting a chemical called Sodium Hypochlorite (similar to household bleach) through a mixer at the very beginning of the disinfection chamber.
Sodium bisulfite is used to remove (neutralize) any residual chlorine.
The equipment used to monitor the residual controls the amount of sodium bisulfite used.
www.gbmsd.org /process/liq-disinfection.shtml   (181 words)

  
 Cape May Foods Recalls Canned Shellfish Because of Label Error   (Site not responding. Last check: 2007-10-10)
The Scungilli was labeled without reference to the presence of sodium bisulfite, a common additive used to preserve color.
Some people are allergic to sodium bisulfite and, accordingly, the product label should include reference to the presence of sodium bisulfite so that consumers can be aware and take appropriate precautions.
If a consumer is not allergic to sodium bisulfite, they may use the product as anticipated, the product itself is wholesome and fit for human consumption.
www.fda.gov /oc/po/firmrecalls/capemay12_01.html   (327 words)

  
 Protocol Online: Bisulfite Modification of DNA
Abstract: Modifying DNA using sodium bisulfite to convert unmethylated cytosines to uracils and subsequently detect methylated cytosines using methylation specific PCR (MSP) technique or bisulfite genomic sequencing after PCR amplification with or without cloning.
40.5% or 3.9 M sodium bisulfite (Sigma; #S 8890, 8.1 g/20 ml), dissolve 8.1 g sodium bisulfite in 17 ml cold water, adjust pH to 5.0 with 10 N NaOH, add water to bring volume 20 ml).
Alternatively, 2M sodium metabisulfite can be used instead, which is equivalent to 3.9 M sodium bisulfite in molarity.
www.protocol-online.org /prot/Detailed/3160.html   (858 words)

  
 ANNEX 2 - Chemical destruction methods for cytostatic drugs
The strength of sodium hypochlorite solutions may be given as weight/weight or weight/volume, which is an additional reason for estimating the concentration of available chorine.
Rinse and titrate with 0.1mol/litre sodium thiosulfate solution, using starch as indicator; 1ml of 0.1mol/litre sodium thiosulfate solution corresponds to 3.545mg active chlorine.
After addition of 1.5g sodium thiosulfate to the neutralized reaction mixture, the medium is made strongly alkaline with 20g/100ml sodium hydroxide solution and the reaction is allowed to proceed for 1 hour.
www.who.int /docstore/water_sanitation_health/wastemanag/ch21.htm   (4469 words)

  
 Bisulfite genomic sequencing: systematic investigation of critical experimental parameters -- Grunau et al. 29 (13): ...
Bisulfite genomic sequencing: systematic investigation of critical experimental parameters -- Grunau et al.
Plasmid DNA was treated with sodium bisulfite solution for 4 h at 0, 15, 35 and 55°C, PCR amplified and sequenced.
Degradation of single-stranded M13mp18 DNA during bisulfite treatment as a function of time: M13mp18 DNA was treated with sodium bisulfite for 5, 15 and 60 min at 55°C. After the treatment the DNA was incubated with nuclease P1 to generate 5' monophosphate nucleotides.
nar.oxfordjournals.org /cgi/content/full/29/13/e65   (4188 words)

  
 Reagents - Sodium Bisulfite
Sodium Bisulfite, Granular, Reagent, 500g - Single Unit
Sodium Bisulfite, Granular, Lab, 500g - Single Unit
Sodium Bisulfite, Granular, Lab, 2.5Kg - Single Unit
www.chemassociates.com /shopsite/Chemassoc2/PAS-sodiumbisulfite.html   (48 words)

  
 RTC # 02-034 attachment
Design services (preparation of plans and technical specifications) for construction of a sodium bisulfite feed system, for use in dechlorinating recycled water and plant No. 3 water.
Sodium bisulfite is metered into the sidestream via a temporary system consisting of a bisulfite storage tank and metering pump.
The overall objective of the project is to replace the existing temporary recycled water bisulfite feed system, expand its function to include dechlorination of plant No. 3 water, and integrate the new system into the existing plant SCADA system.
sunnyvale.ca.gov /200208/rtcs/02-348a2.htm   (2510 words)

  
 Sodium bisulfite Use
Sodium bisulfite - Pesticide use statistics for 2003
Top 50 Crops and Sites for for Sodium bisulfite use in California in 2003
Regional Use for Sodium bisulfite on All Sites in 2003
www.pesticideinfo.org /Detail_ChemUse.jsp?Rec_Id=PC34354   (890 words)

  
 [No title]   (Site not responding. Last check: 2007-10-10)
Yes, I'm talking NaI, Sodium iodide, this really is something you can make at home, you see along time ago, a man came up with the bisulfite addition, well he didn't come up with it, he merely read vogel's practical organic chemistry from front to back,.
A more convenient proceedure is to make use of the addition compound with sodium iodide (NaI,3C3H6O), which decomposes on gentle heating and is particularly well adapted for the preperation of pure acetone.
One hundred grams of finely powdered sodium iodide are dissolved under reflux in 440f of commercial acetone, and the solution is cooled in a mixture of ice and salt(-8C).
www.erowid.org /archive/rhodium/chemistry/naicomplex.txt   (441 words)

  
 Sod. Bisulfite
Sodium bisulfite is a reducing agent made available in a ready-to-use liquid form.
Sodium bisulfite comes in two solutions, 40% and 43%.
Products include: activated alum, aluminum chloride, aluminum chlorohydrate, aluminum sulfate, aqua ammonia, ammonium hydroxide, magnesium sulfate, sodium aluminate, sodium bisulfite, sodium sulfite, sodium thiosulfate, zirconium orthosulfate, zirconium oxychloride.
www.southernionics.com /products/bisulfite.htm   (132 words)

  
 Sodium benzoate thru urea.
Sodium Metabisulfite, Granular, NF, EP, BP, JP 500 g
Sodium Metabisulfite, Granular, NF, EP, BP, JP 12 kg
Sodium Metabisulfite, Granular, NF, EP, BP, JP 45 kg
www.vgdllc.com /SOD-TRIP.htm   (367 words)

  
 PCR/Bisulfite Conversion Based PCR Protocols
The bisulfite reaction reaction was first described in early 1970s and was used by Frommer et al to distinguish between cytosine and 5mCytosine (5mC) in DNA.
In this reaction, DNA is first treated with sodium bisulfite to convert cytosine residues to uracil in single stranded DNA, under conditions whereby 5mC remains essentially non-reactive.
All methods share the same procedure of modifying DNA with sodium bisulfite as the first step and subsequently PCR amplification with primers specific for modified DNA.
www.protocol-online.org /prot/Molecular_Biology/PCR/Bisulfite_Conversion_Based_PCR   (276 words)

  
 Dechlorination Design Standards
Chemical Reaction Dose Ratios for the following dechlorinating chemicals to total chlorine residual are as follows: sulfur dioxide = 1.1 to 1; sodium metabisulfite = 1.5 to 1; sodium bisulfite = 1.5 to 1: and, sodium sulfite = 1.8 to 1.
System Capacity should be designed to provide a dosage of 2 mg/1 of sulfur dioxide at peak design flow.
On-site Chemical Storage should be provided for a minimum of 28 days, at average design flow using the appropriate system capacity dose (i.e., 2 mg/1 for sulfur dioxide, 3 mg/1 for sodium metabisulfite and sodium bisulfite or 4 mg/1 for sodium sulfite).
www.state.me.us /dep/blwq/ddds.htm   (271 words)

  
 Sodium Bisulfite from Holland Company
Holland Company initiated production of Sodium Bisulfite in the Summer of 2003.
Sodium Bisulfite is widely used to dechlorinate process or wastewater effluents prior to discharge.
Products: Aluminum Sulfate Polyaluminum Chloride Sodium Aluminate Dry Alums Sodium Bisulfite
www.hollandcompany.com /aluminum_based_products/sodium_bisulfite.asp   (97 words)

  
 NaHSO3   (Site not responding. Last check: 2007-10-10)
Dose-response curves for sodium bisulfite (experiment 920721) in the MLA.
Sodium bisulfite induces mostly small colony mutants, suggesting an ability to induce primarily chromosome damage (but at quite high concentrations relative to that found in foods).
E-Mail Me This site is best viewed in Netscape Navigator 4.x or Microsoft Internet Explorer 4.x or higher with the screen set to 800 x 600 pixels.
www.mlamutations.com /othermutagens2/NaHSO3/nahso3.html   (152 words)

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