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Topic: Sodium monofluorophosphate

	Fluorides (IARC Summary & Evaluation, Supplement7, 1987)
		Sodium fluoride was tested in three experiments in three different strains of mice by oral administration.
		Sodium fluoride did not induce DNA strand breaks in testicular cells of rats treated in vivo and did not cause chromosomal aberrations in bone-marrow or testicular cells or sister chromatid exchanges in bone-marrow cells of mice treated in vivo.
		Stannous fluoride, sodium monofluorophosphate and sodium silicofluoride did not induce sex-linked recessive lethal mutation in Drosophila, and sodium monoflourophosphate did not induce dominant lethal mutations in Drosophila [ref: 7].
	www.inchem.org /documents/iarc/suppl7/fluorides.html (588 words)

	FDA > CDRH > CFR Title 21 Database Search
		Sodium fluoride 0.188 to 0.254 percent with an available fluoride ion concentration of [gteqt] 850 ppm for products containing the abrasive sodium bicarbonate and a poured-bulk density of 1.0 to 1.2 grams per milliliter.
		Sodium monofluorophosphate 0.654 to 0.884 percent with an available fluoride ion concentration (consisting of PO- combined) = 800 ppm.
		Sodium monofluorophosphate 1.153 percent with an available fluoride ion concentration (consisting of PO- combined) = 1,275 ppm.
	www.accessdata.fda.gov /scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=355&showFR=1 (2327 words)

	[No title]
		An aqueous solution of acidulated phosphate fluoride derived from sodium fluoride acidulated with a mixture of sodium phosphate, dibasic, and phosphoric acid to a pH of 3.5 and which yields an effective fluoride ion concentration of 0.01 percent.
		Sodium fluoride concentrate containing adequate directions for mixing with water before using to result in a 0.02-percent or 0.05-percent aqueous solution with a pH of approximately 7.
		Sodium monofluorophosphate 0.654 to 0.884 percent with an available fluoride ion concentration (consisting of PO3 F= and F- combined) andgteqt; 800 ppm.
	eil.stanford.edu /regnet/resources/21cfr/21.cfr.355.xml (1981 words)

	Dentifrices containing alpha-alumina trihydrate - Patent 4343786
		A toothpaste as in claim 4 in which said alkali metal monofluorophosphate is sodium monofluorophosphate and said alkali metal fluoride is sodium fluoride.
		The foregoing formulation may be made in a conventional manner as by mixing the humectant (sorbitol), gelling agent (dentifrice grade sodium carboxymethyl cellulose) and water, adding saccharin, benzoic acid and flavour, then adding the abrasive (alpha-alumina trihydrate), including the finely divided titanium dioxide whitener, deaerating, and mixing in the detergent (sodium lauryl sulphate).
		From the foregoing it will be observed that the use of sodium fluoride in the toothpaste containing alpha-alumina trihydrate of high alkalinity tends to cause attack of unlined aluminum tubes even when the initial pH of the toothpaste is such that attack would be inhibited in the absence of the sodium fluoride.
	www.freepatentsonline.com /4343786.html (4841 words)

	7. Fluoride therapy for osteoporosis (Site not responding. Last check: 2007-11-06)
		These studies were criticized, mainly on the basis of the fluoride dose and pharmaceutical preparation used,[810] and a subsequent re-evaluation of the data from the Mayo Clinic study[11] suggested that the adverse effects of the initial study[7] might be accounted for in part by the high fluoride dose used.
		Sodium monofluorophosphate (Na) produces no gastrointestinal toxicity, but can give rise to skeletal toxicity.[28] Slow-release NaF (SR-NaF) appears to have a significant osteogenic action without side effects when given intermittently.[15] The intermittent dosage schedule may be responsible for part of the benefit of this treatment.
		Sodium fluoride as an initiator of osteogenesis from embryonic mesenchyme in vitro.
	fluoride.oralhealth.org /papers/1999/cmajno7.htm (4249 words)

	DrBunn.com - About Toothpaste
		Some people are sensitive to a common ingredient in most toothpaste called sodium lauryl sulfate that can cause canker sores.
		For example, a 10% w/w solution of sodium fluoride would be made by first dissolving 10 grams of sodium fluoride in a solvent (most probably water in this case) and then adding solvent to a final weight of 100 grams of solution.
		For example, a 10% w/v sodium fluoride solution would be prepared by dissolving 10 grams of sodium fluoride in 100ml of water.
	www.drbunn.com /tthpste.htm (1605 words)

	Toothpastes with reduced salinity - Patent 4415549
		Toothpaste compositions having monoammonium glycyrrhizinate, strontium disodium ethylenediamine tetraacetate and sodium fluoride or sodium monofluorophosphate.
		This invention relates to toothpaste compositions containing strontium disodium ethylenediamine tetraacetate and, as the source of available fluoride, either sodium fluoride or sodium monofluorophosphate or both, to which is added a minor amount of monoammonium glycyrrhizinate to substantially reduce or suppress salinity.
		A wide variety of dentifrice compositions containing sodium fluoride and/or sodium monofluorophosphate to prevent tooth decay have been known for some time (usual fluorine content: 200 to 1000 ppm).
	www.freepatentsonline.com /4415549.html (971 words)

	UltrabrightToothpaste (Site not responding. Last check: 2007-11-06)
		Most brands of toothpaste have sodium monofluorophosphate or sodium fluoride as their active ingredient.
		The chemical formula of sodium monofluorophosphate is Na with one oxygen double bonded to the phosphorous atom, and the others bonded with a single bond.
		Sodium monofluorophosphate is also known as disodium monofluorophosphate and sodium monofluorophosphate.
	www.cas.astate.edu /draganjac/UltrabrightToothpaste1.html (127 words)

	New Page 5
		A critical review of the 10 pivotal caries clinical studies used in a recent meta-analysis comparing the anticaries efficacy of sodium fluoride and sodium Monofluorophosphate dentifrices.
		Schoolchildren residing in Maine, USA received a baseline caries clinical examination and then were randomly assigned to the twice-daily use of one of the three dentifrices which were purchased in the marketplace and repackaged in plain white tubes.
		Toothbrushing with a sodium fluoride-positive control dentifrice for two-week periods always produced positive remineralization of the lesions, and similar use of a placebo always produced mean mineral loss.
	www.dr-kang.com /cariology.htm (1837 words)

	MEDICINA
		Sodium monofluorophosphate (MFP) is a drug used in the treatment of primary osteoporosis.
		Sodium monofluorophosphate (MFP) is a drug used in the treatment of primary osteoporosis1, 2.
		Pharmacokinetic differences between sodium fluoride and sodium monofluorophosphate and comparative bone mass increasing activity of both compounds in the rat.
	www.medicinabuenosaires.com /vol59-99/2/mfp.htm (3871 words)

	Section 21CFR310.545
		Hydrogen fluoride Sodium carbonate Sodium monofluorophosphate (6 percent rinse) Sodium phosphate (ii) Approved as of October 7, 1996.
		Sodium dihydrogen phosphate Sodium dihydrogen phosphate monohydrate Sodium phosphate, dibasic anhydrous reagent
		Bismuth sodium tartrate Calcium carbonate Cellulase Dehydrocholic acid Dihydroxyaluminum sodium carbonate Duodenal substance Garlic, dehydrated Glutamic acid hydrochloride Hemicellulase Homatropine methylbromide Magnesium hydroxide Magnesium trisilicate Ox bile extract Pancreatin Pancrelipase Papain Peppermint oil Pepsin Sodium bicarbonate Sodium citrate Sorbitol (ii) Approved as of November 10, 1993.
	a257.g.akamaitech.net /7/257/2422/14mar20010800/edocket.access.gpo.gov/cfr_2002/aprqtr/21cfr310.545.htm (1974 words)

	Section 21CFR355.10 (Site not responding. Last check: 2007-11-06)
		Sodium fluoride 0.188 to 0.254 percent with an available fluoride ion concentration [ge] 650 parts per million (ppm).
		Sodium fluoride 0.188 to 0.254 percent with an available fluoride ion concentration of ; 850 ppm for products containing the abrasive sodium bicarbonate and a poured-bulk density of 1.0 to 1.2 grams per milliliter.
		Sodium monofluorophosphate 0.654 to 0.884 percent with an available fluoride ion concentration (consisting of PO and F
	a257.g.akamaitech.net /7/257/2422/14mar20010800/edocket.access.gpo.gov/cfr_2002/aprqtr/21cfr355.10.htm (449 words)

	Sodium Monofluorophosphate ( MFP ) - a part of the history of nerve agents research (DFP - Sarin - Soman)
		Though he could prepare a number of monofluorophosphate salts (among them the sodium, ammonium, potassium, silver monofluorophosphates) he was unable to prepare the free monofluorophosphoric acid, which fact posed a challenge to him (15).
		During 1954 to 1957, certain data was published -by the stannous fluoride research group at the University of Indiana- indicating the relative ineffectiveness of sodium monofluorophosphate in the inhibition of dental caries.
		Sodium monofluorophosphate is being used "regularly or experimentally in dental preparations manufactured in Hong Kong, Formosa, Switzerland and Sweden, as well as the U.S. Difluorophosphoric acid has been sold now for several years on a small scale as a polymerization catalyst.
	www.fluoride-history.de /p-mfp.htm (6320 words)

	Ingredient Analysis: Aquafresh Toothpaste (Site not responding. Last check: 2007-11-06)
		Sodium saccharin is present as an artificial sweetener.
		Sodium hydroxide acts as a base, to neutralise the low pH conditions produced by plaque bacteria and to enable their easy removal.
		Like sodium monofluorophosphate it acts as a source of fluorine, and hence as an anticaries agent.
	www.chem.ox.ac.uk /course/ityeartwo/html/aquafreshtoothpaste.htm (311 words)

	Safeway Oracle Toothpaste (Site not responding. Last check: 2007-11-06)
		This may be the basis for another function: to give the toothpaste "structure" and include granules which assist in cleaning plaque off teeth.
		Synonyms: Cellulose carboxymethyl ether, sodium; CMC Sodium Salt; Carboxymethyl Cellulose, Sodium Salt; Cellex; Aquacide I, Calbiochem; Aquacide II, Calbiochem; Sodium carboxymethyl cellulose.
		Sodium saccharin (NaSac) has been used as an artificial sweetener since the late 1800's.
	www.chem.ox.ac.uk /course/ityeartwo/html/SafewayOracleToothpaste.htm (586 words)

	A simple decoding of toothpaste ingredients (6/07/2000) (Site not responding. Last check: 2007-11-06)
		I am testing a toothpaste with the ingredients sodium fluoride, sorbitol, PEG-6, tetrasodium pyrophosphate, poloxamer 407, sodium carbonate, carnauba wax, blue 1 and yellow 5.
		Here goes: Sodium fluoride and sodium monofluorophosphate are ingredients to get fluoride into your teeth to make them harder and more cavity-resistant.
		Sodium carbonate is a cleanser and neutralizes acids.
	fluoride.oralhealth.org /papers/2000/stpaulpioneerpress060700.htm (197 words)

	World Congress on Osteoporosis (Site not responding. Last check: 2007-11-06)
		Efficacy of Therapy of Involutional Osteoporosis with Disodium Monofluorophosphate and Calcium.
		Monofluorophosphate Decreases Vertebral Fracture Rate in Postmenopausal Osteoporosis: A Randomized, Placebo- Controlled, Double-Blind Study (published in: Ann Intern Med 1998;129:1-8).
		Effects of Combination Therapy with Biphosphonate and Sodium Monofluorophosphate on Bone Mass in Osteoporosis.
	www.mfp-fluoride.com /wco.html (284 words)

	Tom's of Maine - Natural Toothpaste: VillageGreenMarket
		Using naturally sourced sodium fluoride, our Natural Anticavity plus Whitening Liquid Gel Toothpaste with Fluoride helps strengthen teeth and fights cavities from the root to the crown.
		Ingredients: Sodium fluoride, sorbitol, water, hydated silica, glycerin, xylitol, spearmint and peppermint oils, sodium lauryl sulfate, xanthan gum.
		Ingredients: Sodium fluoride, sorbitol, water, hydated silica, glycerin, xylitol, sodium lauryl sulfate, cinnamon and peppermint oils with other natural flavors, xanthan gum, menthol.
	www.villagegreenmarket.com /html/tom60016a.html (379 words)

	Efficacy of a Dentifrice Containing 5% Potassium Nitrate and 1500 PPM Sodium Monofluorophosphate in a Precipitated ... (Site not responding. Last check: 2007-11-06)
		The effect on dentinal hypersensitivity from the use of a dentifrice containing 5.0% potassium nitrate, 1500 ppm sodium monofluorophosphate in a precipitated calcium carbonate (PCC) base over an eight-week period was compared to a placebo dentifrice without potassium nitrate.
		A total of forty-eight subjects were entered into the study and stratified into two balanced groups according to their baseline mean thermal (air blast) and tactile (Yeaple Probe) sensitivity scores.
		Thus it can be concluded from this study that the use of a dentifrice containing 5.0% potassium nitrate and 1500 ppm sodium monofluorophosphate in a precipitated calcium carbonate (PCC) base is a clinically effective method for reducing dentinal hypersensitivity.
	www.jclindent.com /Abstracts/Schiff_v915.html (367 words)

	Toothpaste Baking Soda Gingermint 4 Oz @ $2.84 (077326103043) SKU:19318. Herbal Product Buy Toothpaste Baking Soda ...
		We include the active ingredient sodium monofluorophosphate, sourced from calcium fluoride to safely clean and help relieve cavities.
		Sodium bicarbonate (NaHCO3), commonly known as baking soda, is a time-honored odor absorber and acid neutralizer.
		Baking soda can be found as a naturally occurring compound, but is more frequently manufactured from other naturally derived materials.
	www.herbspro.com /shop/xq/asp/pid.18162/qx/productdetail.asp (449 words)

	Merodent
		This Sodium Fluoride toothpaste is recognized by the American Dental Association for its effective decay-preventive properties when used in a conscientiously applied program of oral hygiene and regular professional care.
		For Children Tiger Teeth Toothpaste's unique bubble gum flavor encourages children to brush more often, so parents can be assured that their children are getting the cavity fighting fluoride protection that they need.
		These toothpastes combine the cavity protection of Sodium Fluoride with tartar fighting pyrophosphates to help reduce tartar buildup on your teeth.
	www.merodent.com /products.html (1262 words)

	eMedicine - Toxicity, Fluoride : Article by Geofrey Nochimson, MD (Site not responding. Last check: 2007-11-06)
		Toothpaste contains 1 mg/g of fluoride as sodium monofluorophosphate.
		This fluoride formulation has low solubility and is generally nontoxic.
		Ventricular fibrillation not associated with hyperkalemia; digitalis toxicity, hypercalcemia, renal insufficiency, cardiac disease
	www.emedicine.com /emerg/topic181.htm (1477 words)

	Sodium Monofluorophosphate - China Sodium Monofluorophosphate Manufacturer, China Sodium Monofluorophosphate Supplier
		Properties: White solid whose melting point is 625ºC. Sodium monofluorophosphate accounts for 42% of the saturated solution at 25ºC. The PH value of its dilute solution (2%) is 6.5--8.
		It is also used to clean the metal surfact and make special glass, as melting agent, etc..
		Your use of this website is subject to, and constitutes acknowledgement and acceptance of, our Terms & Conditions.
	www.made-in-china.com /products/show/freemember/prod/zg5NzQM/mic/Chemicals_Specialized_Preparation_Sodium_Monofluorophosphate.html (180 words)

	Astera Herbal Toothpaste [www.bpg.bg/aroma]
		Contains a special natural extract of Chamomile, Balm Mint, Rosemary, Sage, Tormentil and Witch Hazel to prevent inflammation and soothe, regenerate and reinforce gum tissue, while fighting bad breath.
		Sodium monofluorophosphate strengthens, and remineralizes tooth enamel and protects against cavities.
		Ingredients: Aqua, Hydrated Silica, Sorbitol, PEG-8, Sodium Lauryl Sulfate, Cellulose Gum, Aroma, Titanium Dioxide, Sodium Monofluorophosphate – 076%, Chamomila recutita, Melissa officinalis, Rosmarinus officinalis, Salvia officinalis, Potentilla erecta, Hamamelis virginiana, Sodium Saccharin, Methylparaben, 2-Bromo-2-Nitropropane-1,3-Diol – 0.02%, Cl 19140, Cl 42090
	www.bpg.bg /aroma/toothpaste/20134astera_herbal.htm (131 words)

	Tom's of Maine - Anti-Cavity Fluoride Natural Toothpaste: VillageGreenMarket
		Tom's of Maine toothpastes are made with the finest natural ingredients for cleaning, and flavored with natural oils for great taste.
		Ingredients: Sodium monofluorophosphate, glycerin, water, calcium carbonate, hydrated silica, xylitol, carrageenan, sodium lauryl sulfate, wintergreen oil and other natural flavors.
		Ingredients: Sodium monofluorophosphate, calcium carbonate, glycerin, water, sodium bicarbonate (baking soda), carrageenan, xylitol, peppermint oil, sodium lauryl sulfate.
	www.villagegreenmarket.com /html/tom60015.html (299 words)

	Jason Natural - Flouride Gel - Nutri Smile Plus CoQ10, 6 oz
		High Potency Ester-C Liquid: a complex of Calcium, Sodium, Magnesium and Zinc Ascorbates; and L-Ascorbic Acid - helps reinforce tooth enamel and helps defend against decay.
		Sodium, monofluorophosphate calcium, sodium, magnesium, zinc ascorbates, l-ascorbic acid, perilla seed extract, glycerin, stevioside, grapefruit seed extract, cellulose gum, sodium bicarbonate, bamboo powder, sodium cocoyl glutamate, calcium carbonate, aqua, silica/silicate, zylitol, aloe vera gel, coq10, oil of orange, co-enzyme a, msm, oil of cinnamon, oil of mint.
		Adults and children 2 years of age and older: Brush teeth thoroughly, preferable after each meal or at least twice a day, or as directed by a dentist or physician.
	www.iaromatherapy.com /shop/detail.cfm/sku/57112 (380 words)

	Fluoride toothpastes, rinses, and tablets -- Stephen 8 (2): 185 -- Advances in Dental Research
		described where a sodium fluoride dentifrice successfully reduced root
		fluoride (1000 ppm F), and amine fluoride (250 ppm F)], sodium fluoride
		caries-inhibiting benefit as compared with sodium fluoride alone.
	adr.iadrjournals.org /cgi/content/abstract/8/2/185 (247 words)

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