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Topic: Sodium picosulfate

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	Patent 4948591: Soft capsular preparation of sodium picosulfate
		The soft capsular preparation according to claim 1, wherein the ratio of polyethylene glycol/sodium picosulfate is at least 4 parts by weight of polyethylene glycol per 1 part by weight of sodium picosulfate.
		The soft capsular preparation according to claim 2, wherein the ratio of polyethylene glycol/sodium picosulfate is 8 to 45 parts by weight of polyethylene glycol per 1 part by weight of sodium picosulfate.
		In view of this situation, the present inventors have undertaken extensive studies, and found that a soft capsular preparation of sodium picosulfate which is stable for an extended period of time can be prepared by dissolving sodium picosulfate in polyethylene glycol and encapsulating the solution into a soft capsular film.
	www.freepatentsonline.com /4948591.html (1329 words)

	971. Sodium sulfate (WHO Food Additives Series 44)
		Sodium sulfate was not specifically included in that ADI because no information was available to indicate that it was being manufactured or used as a food-grade material.
		When sodium sulfate was included in the treatment, the mean quantity of acetaminophen sulfate excreted in the urine increased but the difference from the treatment without sodium sulfate did not achieve statistical significance.
		Sodium sulfate decahydrate and its anhydrous salt are listed in Martindale's Pharmacopoeia, and the laxative use is noted; another medical use recorded is in the treatment of severe hypercalcaemia, in which it is given by slow intravenous administration of a 3.9% aqueous solution.
	www.inchem.org /documents/jecfa/jecmono/v44jec07.htm (1869 words)

	Australian Prescriber (Site not responding. Last check: 2007-11-06)
		When sodium phosphate is given orally, diarrhoea occurs within 0.5–4 hours while a bowel action occurs within 10–15 minutes after rectal administration.
		Sodium phosphate must therefore be avoided in patients with impaired renal function and used with great care in the presence of congestive cardiac failure because of the potential large fluid shifts.
		A combination of magnesium sulfate and sodium picosulfate is a commonly prescribed oral bowel preparation, presented in two sachets.
	www.australianprescriber.com /index.php?content=/magazines/vol28no1/16_17_bowel.htm (1011 words)

	Sodium Picosulfate - Patient UK
		Sodium Picosulfate is used to treat constipation and is sometimes used to clear the bowel before medical examinations that require the bowel to be empty.
		Sodium Picosulfate works by encouraging the bowel to contract and move the waste products along the bowel helping you to go to the toilet.
		Sodium Picosulfate is available in oral liquid and capsule form.
	www.patient.co.uk /showdoc/30002087 (676 words)

	Diagnose-Me: Sodium
		The remaining 57 percent or so of the body sodium content is in the fluid immediately surrounding the cells, where it is the major cation (positive ion).
		The role of sodium in the extracellular fluid is maintaining osmotic equilibrium (the proper difference in ions dissolved in the fluids inside and outside the cell) and extracellular fluid volume.
		Sodium is also involved in nerve impulse transmission, muscle tone and nutrient transport.
	www.diagnose-me.com /glossary/G750.html (1683 words)

	Australian Adverse Drug Reactions Bulletin, February 2002
		Low volume bowel preparations for colonoscopy have become increasingly popular in recent years because of the greater comfort for patients who are not required to swallow large volumes of liquid.
		Sodium picosulfate acts similarly to sodium phosphate in that it produces its cathartic effect by osmotic action in the gut.
		Low volume sodium phosphate and sodium picosulfate products can cause marked dehydration, hyponatraemia, other electrolyte abnormalities and associated complications.
	www.tga.gov.au /docs/html/aadrbltn/aadr0202.htm (1254 words)

	Diagnose-Me: Stimulant Laxative
		Stimulant laxatives are believed to stimulate nerve endings in the nerve plexuses of the bowel wall, increasing the movement of its content via several mechanisms.
		The most common active ingredients include the Anthraquinones (Senna, Aloin, Frangula, Cascara and Powdered rhubarb) and the Diphenylmethane derivatives (Bisacodyl, Sodium picosulfate, Phenolphthalein).
		"...An example is docusate sodium, an anionic surfactant that also exerts a
	www.diagnose-me.com /glossary/G1263.html (104 words)

	Laxative for constipation relief, colon cleansing and weight loss. Weight loss herbal formula. DHEA. Online Pharmacy ...
		We tested the laxative sodium picosulfate for mechanical bowel preparation in elective colorectal surgery.
		The quality of this preparation was assessed on a visual analog scale on 277 patients who were then followed prospectively for wound and intraabdominal infectious complications for 42 days.
		Picosulfate preparation resulted in a complication rate similar to whole gut irrigation but was more acceptable for the patients and the nurses.
	dreampharm.com /ref-laxative/laxative-research-abs3.6.html (651 words)

	Benkwitz, Catharina - Abstract (Site not responding. Last check: 2007-11-06)
		5, 10 and 15 mg sodium picosulfate drops or placebo orally in a single dose.
		(the active principle of sodium picosulfate) and tolerability were tested.
		are the result of motility stimulating effect of sodium picosulfate.
	edoc.hu-berlin.de /abstract.php3?id=3000248 (289 words)

	Managing constipation in children (Site not responding. Last check: 2007-11-06)
		If the child has a megarectum impacted with hard stools, stimulant laxatives may aggravate overflow faecal incontinence and abdominal pain; using docusate, a stimulant laxative with stool-softening properties, is a reasonable option in this situation.
		If rectal preparations are required, small-volume sodium citrate enemas (micro-enemas) should be used in preference to the larger-volume phosphate enemas; some older children can be taught to self-administer micro-enemas.
		Children may be particularly anxious about rectal treatments if they have experienced anal pain or abuse and may interpret rectal administration as punishment, especially when the enema is presented as a threat.
	www.australianprescriber.com /magazines/vol25no4/constipation.htm (2296 words)

	Laxatives (Site not responding. Last check: 2007-11-06)
		Micro Enemas or Phosphate Enemas may also be useful as bowel evacuants after stimulant administration.
		Docusate Sodium is a faecal softener and weak stimulant which may be useful in the elderly to soften impacted faeces or to reduce strain.
		Lactulose should not be given with mesalazine since it prevents its release in the colon.
	www.pillroller.freeserve.co.uk /pages/laxatives.htm (795 words)

	Agenda Items for the Next Medicines Classification Committee Meeting
		This would bring the classification of sodium picolsulfate into line with that of sodium phosphate and those macrogols which are used for similar indications.
		Sodium picosulfate is currently a pharmacy-only medicine along with other stimulant laxatives.
		The classification change for bowel cleansing would bring it into line with sodium phosphate and the macrogols which are used in this way.
	www.medsafe.govt.nz /Profs/Class/agen28.htm (635 words)

	Constipation and the Use of Laxatives
		The most widely used laxatives are the stimulant preparations: those containing senna, bisacodyl and sodium picosulfate and wheat bran and lactulose
		The classical adverse effect of laxatives is diarrhea, which may result in severe metabolic disturbances caused by depletion of electrolytes.
		Colace (dicotyl sodium) has the potential to result in electrolyte imbalance, which is reversible on stopping the Colace.
	www.therubins.com /health/laxatives.htm (2079 words)

	[No title]
		Sodium nitroprusside 50mg I.V. infusion Vial with solvent
		Sodium nitroprusside 50mg I.V. infusion Ampoule with solvent
		Sodium acid phosphate 21.4g+Sodium phosphate 9.4g /133 ml single dose enema
	www.un.org /Depts/oip/cpmd/ft-humanmeds.html (747 words)

	Laxative for constipation relief, colon cleansing and weight loss. Weight loss herbal formula. DHEA. Online Pharmacy ...
		Investigation and diagnosis of diarrhea caused by sodium phosphate.
		Effects of long-term treatment with anthranoids and sodium picosulphate on the contents of vasoactive intestinal polypeptide, somatostatin and substance P in the rat colon.
		Studies on the mechanism of action of dioctyl sodium sulphosuccinate in the human jejunum.
	www.dreampharm.com /ref-laxative/laxative-refs.html (1873 words)

	Pharmaceutical News,Drugs Control,Health,Diagnostic,Doctors,Medicines,Rajasthan,India
		Many of the reports (129) documented a serum sodium concentration and in 75 cases, the concentration was less than or equal to 120 mmol/L. Despite the fact that hyponatraemia can complicate treatment with any diuretic medication, ADRAC continues to receive reports of the association.
		Pure red cell aplasia (PRCA) is a rare adverse effect of epoetin alfa, which has recently been highlighted in an article and subsequent letter in the literature.1,2 The condition results from the development of antierythropoietin antibodies, resulting in transfusion-dependent anaemia.
		ADRAC has previously highlighted the risk of severe electrolyte disturbances in association with the use of oral sodium phosphate solution (Fleet Phospho-Soda Buffered Saline Laxative Mixture, Kwikprep) as a bowel preparation.1 Since then, ADRAC has received reports in association with two other products (Picolax, Picoprep) which contain sodium picosulfate.
	www.drugscontrol.org /adverse_cases.htm (9066 words)

	Medicines - Laxatives
		are elderly or debilitated (some laxatives can alter the balance of fluid and important body chemicals such as sodium and potassium.
		Docusate sodium (Dioctyl, Docusol, Fletcher's Enemette, Norgalax Micro-enema)
		Most doctors and pharmacists consider that powerful stimulants such as castor oil and cascara have now been replaced by better preparations.
	www.bupa.co.uk /health_information/html/medicine/laxatives.html (971 words)

	[No title]
		Other drugs that may be combined with antacid formulations include simeticone, which acts as a defoaming agent to reduce excess gas in the stomach, and alginates, which form a gel or foam on the surface of the stomach contents thereby impeding reflux and protecting the oesophageal mucosa from acid attack.
		Calcium carbonate and sodium bicarbonate are both rapidly acting but have disadvantages: calcium carbonate is usually reserved for short-term treatment because of the risks of rebound acid secretion and metabolic alkalosis, while sodium bicarbonate is absorbed and is contra-indicated in patients who must control sodium intake (e.g.
		Those described in this chapter include saline laxatives such as magnesium citrate, magnesium hydroxide, and sodium sulfate (for magnesium sulfate and sodium phosphate see and respectively).
	www.kimsonline.co.kr /DrugInfo/specialissue/Zelmac/zelmac_gastrointestinal.html (1415 words)

	IBD_rct (Site not responding. Last check: 2007-11-06)
		Prevention of postoperative abdominal adhesions by a sodium hyaluronate-based bioresorbable membrane: a prospective, randomized, double-blind multicenter study.
		Single-day, divided-dose oral sodium phosphate laxative versus intestinal lavage as preparation for colonoscopy: efficacy and patient tolerance.
		Dioctyl sodium sulphosuccinate as a laxative in the elderly.
	cochrane.mcmaster.ca /ibd/SR.html (13841 words)

	Laxative for constipation relief, colon cleansing and weight loss. Weight loss herbal formula. DHEA. Online Pharmacy ...
		METHOD: 140 outpatients referred for colonoscopy were randomized into three groups for cleansing with 4 litres PEG 4000, 4 litres PEG 3350 or with 90 ml sodium phosphate with an additional 2.5 litres of fluid.
		There has been no study comparing Picoprep-3 (sodium picosulfate), a relatively new product, to Fleet (sodium phosphate), a well-studied and widely used preparation.
		This study was designed to compare the efficacy and patient tolerance of these two bowel preparations for colonoscopy.
	www.dreampharm.com /ref-colon-cleansing/colon-cleansing-research-abs3.2.html (937 words)

	letters (Site not responding. Last check: 2007-11-06)
		SODIUM CHLORIDE 0.45% and GLUCOSE 2.5% VIAFLEX B1023 500ml Intravenous Injection
		SODIUM CHLORIDE VIAFLEX B1322 250ml Intravenous Infusion.9 %
		SODIUM FEREDETATE (Sytron) Elixir (Equiv 55mg FE per 10ml)
	www.pillroller.freeserve.co.uk /pages/letters.htm (205 words)

	Cascara Sagrada : by Ray Sahelian, M.D., Health Benefits of Cascara and research update
		It is best to avoid cascara sagrada if you have a chronic intestinal condition such as ulcerative colitis.
		The purgative effect of bisacodyl, anthraquinone glycosides ( Cascara sagrada), and sodium picosulfate, alone or in combination with a saline purge and a tap water enema, was studied in 1200 patients.
		The cleansing effect was scored with regard to retained fecal residue evident on double-contrast studies of the colon.
	www.raysahelian.com /cascarasagrada.html (524 words)

	Laxoberal liquid (Site not responding. Last check: 2007-11-06)
		After being taken by mouth, sodium picosulfate is activated by the bacteria naturally present in the large intestine.
		It then works by stimulating nerve endings in the intestinal wall.
		This moves the contents of the gut through the intestine so that the bowel can be emptied, and hence relieves constipation.
	www.netdoctor.co.uk /medicines/100001469.html (567 words)

	Tramadol, buy tramadol, antibiotics, Weight Loss drugs, weight loss herbs, weight loss herbal formula, weight loss, ...
		This effect occurred within 1 h after oral administration, mostly within 30 min, whereas sodium picosulfate, a widely used laxative, tended to increase the frequency of defecation for several hours with much lower peak incidence than that of YM-31636, and induced diarrhea.
		These results suggest that YM-31636 could be promising in the treatment of constipation.
		Because of an early and reliable onset of action compared with sodium picosulfate, YM-31636 could make it easier to control the time of defecation.
	www.hairmillion.com /ref-constipation/constipation-research-abs3.319.html (503 words)

	News¡§A Uniquely Fast-Acting Suppository-Type Laxative Colac Suppository-Type Debut (Site not responding. Last check: 2007-11-06)
		The active ingredient bisacodyl is buffered five times to prevent it from dissolving in the stomach, and to make it work potently when the laxative reaches the intestines.
		The active ingredient sodium picosulfate works softly in the intestines.
		Herbal extract sennoside restores correct movement of the large intestine.
	www.taisho.co.jp /outline/rls/htm/03_0626-e.htm (440 words)

	[No title]
		Our main products and their scales are: caustic soda (100, 000 MT/yr), hydrochloric acid, PVC (60, 000 MT/yr), liquid chlorine (30, 000 MT/yr), sodium hypoc-hlorite (20, 000 MT/yr), chlorinated paraffin wax (6, 000 MT/yr) and chlorinated polyethylene (2, 000 MT/yr).
		Gas products series cover hydrogen, super pure hydrogen, oxygen, nitrogen, etc. In addition, there are textile auxiliaries, plastic windows, chemical reagent polyether as well as medical intermediates and R&G health-care food series.
		Free zone, which are fully computerized to satisfy the immediate delivery needs.
	www.bizeurope.com /bsr/sourcing/new032kl.txt (13340 words)

	Durolax® - How Durolax Works (Site not responding. Last check: 2007-11-06)
		Durolax Suppositories, containing Bisacodyl, take effect directly in the rectum and provide more immediate relief within 15-60 minutes.
		Durolax SP Drops, containing Sodium Picosulfate, which is converted into the same active form as Durolax Tablets in the large intestine and provides relief of constipation within 6-12 hours.
		Unlike many other drugs, only very small amounts of Bisacodyl (Durolax Tablets and Suppositories) and Sodium Picosulfate (Durolax SP Drops) access the blood stream and therefore have very few side effects.
	www.durolax.com /au/Main/Dulcolax/HowItWork/index.jsp (186 words)

	Lib #: WA10319 - Analytical control of a pharmaceutical formulation of sodium picosulfate by capillary zone ... (Site not responding. Last check: 2007-11-06)
		Lib #: WA10319 - Analytical control of a pharmaceutical formulation of sodium picosulfate by capillary zone electrophoresis
		If you are having problems opening the PDF, press and hold the Control Key while you click on the PDF.
		Analytical control of a pharmaceutical formulation of sodium picosulfate by capillary zone electrophoresis
	www2.waters.com /Watprod.nsf/Newdocs/WA10319 (87 words)

	Laxatives and enemas (Site not responding. Last check: 2007-11-06)
		preparations: those containing senna, bisacodyl and sodium picosulfate
		Colace (dicotyl sodium) has the potential to result in
		Sodium salts, including Phospho-Soda and Fleet enema can cause
	www.running-forum.com /running/Laxatives_and_enemas_385502.html (1823 words)

	Senokot Liquid / Coupon For Senokot S / Cozaar (Site not responding. Last check: 2007-11-06)
		docusate sodium 50 mg per tablet is the softener in Senokot S).
		Dulco-lax liquid (sodium picosulfate) Dulco-lax perles (sodium picosulfate)...
		Senokot syrup (senna) Senokot tablets (senna) Sodium picosulphate elixir...
	senokot.line-pharmacy.com /senokot_liquid (619 words)

	Low Carb Friends - boulders in my colon!
		JV1311.....what is a brand name for the sodium picosulfate?
		That stuff tends to make me sick and I think I end up losing way too much water.
		08-19-2003, 04:31 PM Something I haven't seen posted on here is ducosate sodium.
	www.lowcarbfriends.com /bbs/archive/index.php/t-136388.html (2163 words)

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