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Sorbitol - Wikipedia, the free encyclopedia Sorbitol, also known as glucitol, is a sugar alcohol the body metabolises slowly. Sorbitol is often used in modern cosmetics as a humectant and thickener. Sorbitol is used as a cryoprotectant additive (mixed with sucrose and sodium polyphosphates) in the manufacture of surimi, a highly refined, uncooked fish paste most commonly produced from Alaska (or walleye) pollock (Theragra chalcogramma). en.wikipedia.org /wiki/Sorbitol   (376 words)

Richard Nakka's Experimental Rocketry Web Site Sorbitol is an artificial sweetener, very similar in appearance and with similar physical characteristics to both sucrose and dextrose sugars. Sorbitol is widely used in industry, in particular, in the manufacture of processed items such as confections, toothpaste, candy and syrups. Since sorbitol is synthesized from glucose, it is conceivable that the trace amounts of glucose were responsible for the slight caramelization. members.aol.com /riccnakk/sorb.html   (3285 words)

349. Sorbitol (WHO Food Additives Series 5) In experiments on rats given sorbitol-U- C by intraperitoneal injection, 57.4% of the activity was excreted as CO, 17.3% in the urine, 4.2% was found as liver glycogen and 0.6% as liver fatty acids. The intravenous infusion of sorbitol in rabbits caused a prompt fructosaemia and a variable secondary glucosaemia occurred later (Seeberg et al., 1955). Dog Sorbitol was excreted by glomerular filtration; the renal clearance in the dog was found to be 74-77 ml/min (Smith et al., 1940). www.inchem.org /documents/jecfa/jecmono/v05je91.htm   (1680 words)

Calorie Control Council | Low-Calorie Sweeteners: Sorbitol Sorbitol has been affirmed as GRAS (Generally Recognized As Safe) by the U.S. Food and Drug Administration and is approved for use by the European Union and numerous countries around the world, including Australia, Canada and Japan. The usefulness of polyols, including sorbitol, as alternatives to sugars and as part of a comprehensive program including proper dental hygiene has been recognized by the American Dental Association.   The FDA has approved the use of a "does not promote tooth decay" health claim in labeling for sugar-free foods that contain sorbitol or other polyols. Absorption of sorbitol by the human body is slow, allowing part of the ingested sorbitol to reach the large intestine where metabolism yields fewer calories. www.caloriecontrol.org /sorbitol.html   (1216 words)

Ingredients -- Sorbitol Sorbitol and mannitol are isomers, substances with the same chemical formula, but a different shape. Sorbitol is used in low calorie candies, and in many foods as both a sweetener and as a humectant (moisture retaining ingredient). Sorbitol is used as an emollient (skin softener) in soaps. www.sci-toys.com /ingredients/sorbitol.html   (157 words)

Petition to FDA for Regulatory Action to Revise the Labeling Requirements for Foods Containing Sorbitol ~ CSPI’s ...   (Site not responding. Last check: 2007-11-04) Sorbitol is a naturally-occurring hexahydric alcohol that is found in various fruits and plants. That study, in which sorbitol was used as a positive control, was designed to measure the chemicals’ effects on subjects’ stool consistency and composition, as well as on the occurrence of gastrointestinal symptoms, including cramping, bloating, flatulence, heartburn, nausea, and urgency. No statistically significant correlation between sorbitol consumption and afebrile diarrhea existed for the other age groups in the study, a fact that the researchers noted may be attributable to flaws in the study design. www.cspinet.org /foodsafety/labeling_sorbitol.html   (5506 words)

SurfWax: News, Reviews and Articles On Sorbitol One of the compounds, sorbitol octanoate, has proved less costly to produce than earlier forms patented, and is now undergoing the process of registration with the U.S. Environmental Protection Agency. The sugar alcohols sorbitol, mannitol, maltitol and xylitol are derived from sucrose, mannose, maltose and xylose respectively... Sugar alcohols (xylitol, maltitol, sorbitol) are structurally similar to their carbohydrate cousins but have an increased number of hydrogen atoms, which, in chemical terms, renders them "hydrogenated" or "reduced"; as a result, they are processed somewhat differently by the body. news.surfwax.com /drugs/files/Sorbitol.html   (562 words)

Sorbitol   (Site not responding. Last check: 2007-11-04) Virent also intends to use sugar in the form of sorbitol and glucose as a feedstock for this initial unit. Sugar alcohol is more commonly known as sorbitol, mannitol, xylitol, maltitol, lactitol, erythritol, isomalt and hydrogenated starch hydrosylates. Sorbitol, a sugar substitute found in many commercial foods, including sugarless chewing gum, is another gas producer. sorbitol.wikiverse.org   (179 words)

Sorbitol news articles   (Site not responding. Last check: 2007-11-04) GABBAY KH: The sorbitol pathway and the complication of diabetes. Sorbitol, a common ingredient in mouthwash and toothpaste is derived from corn. The pellet was resuspended in homogenization buffer (330 mM sorbitol, 50 mM HEPES-NaOH, pH 7.0, 0.1 mM PMSF, 2 mM EDTA, and 0.005% [v/v] Nonidet P-40) to a... www.mongabay.com /drugs/drugs/Sorbitol.html   (2743 words)

Sorbitol   (Site not responding. Last check: 2007-11-04) It is called a nutritive sweetener because it has four calorie s in every gram, just like table sugar and starch. Diabetic retinopathy and neuropathy may be related to too much sorbitol in the cells of the eye s and nerve s. SPI Polyols, Inc. Offers a broad line of sorbitol and mannitol products, in a wide range of particle sizes, and liquid sorbitol solutions. www.serebella.com /encyclopedia/article-Sorbitol.html   (293 words)

Diabetes: Inhibition of sorbitol dehydrogenase: effects o... @ HighBeam Research   (Site not responding. Last check: 2007-11-04) Sorbitol levels in diabetic rats were increased 11- to 14-fold in ocular tissues and sciatic nerve; S-0773 increased sorbitol levels another 4-fold or more in these same tissues but had much smaller effects in other tissues. The increased sorbitol levels in ocular tissues, sciatic nerve, and whole blood, together with the decreased fructose content and lactate:pyruvate ratios in retina and sciatic nerve of diabetic rats given S-0773, are consistent with inhibition of sorbitol dehydrogenase, as predicted in the introduction. The effects of S-0773 on sorbitol pathway metabolites, lactate:pyruvate ratios, and vascular function support the hypothesis that sorbitol pathway-linked, diabetes-induced vascular dysfunction in ocular tissues, sciatic nerve, and aorta is mediated largely by redox and metabolic imbalances associated with increased oxidation of sorbitol to fructose in the second step of the sorbitol pathway (Fig. www.highbeam.com /library/doc0.asp?DOCID=1G1:16650863&refid=holomed_1   (4420 words)

Elevated sorbitol concentration in the cerebrospinal fluid of patients with mood disorders.   (Site not responding. Last check: 2007-11-04) Elevated sorbitol concentration in the cerebrospinal fluid of patients with mood disorders. This study was undertaken to test the hypothesis that a specific pathophysiological mechanism of diabetic neuropathy, namely increased polyol pathway flux, could be operative in patients with bipolar and unipolar mood disorders. The purpose of this study was to determine whether sorbitol concentration is elevated in the CSF of non-medically ill patients with mood disorders. www.arclab.org /medlineupdates/abstract_10840171.html   (211 words)

Case Studies-Sorbitol   (Site not responding. Last check: 2007-11-04) A plant with a current output of 20MT sorbitol per year, would thereby be de-bottlenecked to a capacity of 27.5 MT pa. In case of faster pumping times, the capacity of the above imaginary facility may become higher than 30MT, or a +50% increase. Sorbitol and other polyols are derived from starch. VenPure™ Polisher 2 improves sorbitol quality by eliminating not only the unreduced sugars from the nickel catalyzed hydrogenation, but also any other aldehydic and ketonic impurities that may be produced during manufacturing (e.g. www.rohmhaas.com /process/sorbitol.html   (637 words)

[No title]   (Site not responding. Last check: 2007-11-04) Abrupt temperature change, from 23 to 13°C, 13 to 3°C or vice versa, was used to study the metabolic events associated with cryoprotectant polyol synthesis and the reversibility of polyol accumulations in the overwintering, freezing tolerant larvae of the gall fly, Eurosta solidaginis. Sorbitol synthesis was induced when larvae acclimated to 13°C were abruptly moved to 3°C. A precursor-product relationship between glucose-6-P, glucose and sorbitol was apparent with elevated levels of the compounds in the larvae first detected after 1, 2 and 24 h at 3°C, respectively. Sorbitol, however, is produced only in direct response to cold when freezing temperatures are imminent. www.carleton.ca /~kbstorey/jan7.htm   (231 words)

How Sorbitol Causes Irritable Bowel Syndrome - Foodintol Sorbitol is a natural laxative and occurs in pears, prunes and other fruits. The action of sorbitol is to linger in the gut because it is not digested. Sorbitol is a polyalcohol sugar and is neither digested nor absorbed by the small intestine. www.foodintol.com /food_intolerance/hot_ibs.htm   (1022 words)

Glucose Does Not Facilitate the Absorption of Sorbitol Perfused In Situ in the Human Small Intestine -- Beaugerie et ...   (Site not responding. Last check: 2007-11-04) Sorbitol is a sugar alcohol widely used as a sucrose substitute in dietetic food and beverages because of its physicochemical Sorbitol load entering the test segment and mean sorbitol and glucose concentration in the jejunal segment. Sorbitol was not absorbed to a greater extent when perfused concomitantly with glucose. www.nutrition.org /cgi/content/full/127/2/341   (2478 words)

Diabetes Care: Sural nerve sorbitol in patients with diabetic ... @ HighBeam Research   (Site not responding. Last check: 2007-11-04) Experience has shown that sorbitol levels in human nerve should be determined with sural nerve biopsy before exposing large numbers of patients to potentially toxic compounds in long and expensive clinical trials as not all aldose reductase inhibitors penetrate human peripheral nerve (5). Knowing the expected nerve sorbitol levels in patients with DSP is important in clinical research for two reasons First, the proposed laboratory methodology must be sufficiently sensitive to measure sorbitol levels at the nanomole concentrations typically found in DSP. Furthermore, the concentration of sorbitol in human nerve appears to be less than that found in rat nerve, perhaps because of differences in tissue levels of aldose reductase and sorbitol dehydrogenase or differences in the severity of diabetic hyperglycemia. www.highbeam.com /library/doc0.asp?DOCID=1G1:116666622&refid=holomed_1   (2808 words)

458. Sorbitol (WHO Food Additives Series 13) A higher water intake was seen in both male and female 20% sorbitol rats and was associated with increased urine excretion. However, the incidence of both unilateral and bilateral hyperplasia of the adrenal medulla was increased significantly for both males and females in the 20% sorbitol group. Dog Sorbitol 0 or 20% was administered in the diet of pure-bred beagle dogs (eight male and eight female animals per group). www.inchem.org /documents/jecfa/jecmono/v13je08.htm   (1382 words)

Sorbitol   (Site not responding. Last check: 2007-11-04) It is artificial sweetener used in diet foods. Diabetic retinopathy and neuropathy may be related to too much in the cells of the eyes and nerves. Hepatic metabolism of ethanol and sorbitol in hypo-, hyper- and euthyroid rats, www.freeglossary.com /Sorbitol   (96 words)

Aldose Reductase Induced by Hyperosmotic Stress Mediates Cardiomyocyte Apoptosis: DIFFERENTIAL EFFECTS OF SORBITOL AND ... of hyperosmotic AR induction by sorbitol is depicted in Fig. Intracellular sorbitol accumulation resulted from de novo synthesis by aldose reductase and was not due to sorbitol uptake in cultured cardiac myocytes. to accumulation of intracellular sorbitol in cardiac myocytes. www.jbc.org /cgi/content/full/278/40/38484   (6750 words)

Ambuja Sorbitol   (Site not responding. Last check: 2007-11-04) SORBITOL is widely utilized for diabetic foods and for keeping confectionary and bakery products fresh and to preserve the colour and also improves the keeping quality of canned fruits. SORBITOL is used as an ingredient in a number of pharmaceutical preparations like syrups,olixirs,sulpha drugs, tonics, vitamins and amino acids-complex preparations, laxatives and ointment based for hepatic and diabetic diseases, SORBITOL injections are used. SORBITOL increases the flexibility of paper, thus folding value is higher while the length of rupture and elongation does not change abnormally. www.ambujaglobal.com /sorbitol.htm   (321 words)

SORBITOL : NOW FOODS Sorbitol, originally derived from the mountain sorberry, is a naturally occurring sweetener found primarily in fruits and berries. Because it is absorbed and metabolized slowly, sorbitol has little effect on blood sugar levels. Sorbitol can be used in place of table sugar in drinks, cooking, and recipes. www.alwaysaffordablevitamins.com /6950.html   (254 words)

Consumer Group Petitions FDA to Require "Diarrhea" Notice on Foods that Contain Sorbitol   (Site not responding. Last check: 2007-11-04) Sorbitol is a sweet-tasting sugar alcohol used in many sugar-free or “dietetic” candies, cake mixes, syrups, and other foods, as well as in some medicines. Studies over the past fifteen years have proven that sorbitol can cause gastrointestinal symptoms, ranging from mild discomfort to severe diarrhea, when adults consume between 10 and 50 grams of the additive. “Since even small amounts of sorbitol can cause gastrointestinal symptoms it is important for the FDA to inform the public of this potential problem,” said Dr. Jeffrey S. Hyams, Head, Department of Digestive Diseases and Nutrition, Connecticut Children’s Medical Center, and Professor of Pediatrics, Connecticut University School of Medicine. www.cspinet.org /new/sorbitol_pr.html   (458 words)

114 Sorbitol Special Polyol Solution Sorbitol Special Polyol Solution has a solids content of 76% and a water content of 24% approximately. Sorbitol Special Polyol Solution acts as a barrier to inhibit reaction between polyethylene glycol (PEG) in the fill and gelatin in the capsule shell. Sorbitol Special Polyol Solution is approved worldwide for use in pharmaceutical and nutritional soft gelatin capsules. www.spipharma.com /ProductsFolder/114SorbitolSpecial/114SorbitolSpecial.html   (535 words)

Manipulation of in Vivo Sorbitol Production Alters Boron Uptake and Transport in Tobacco -- Bellaloui et al. 119 (2): ... The aim of this experiment was to verify the role of sorbitol in boron translocation from the mature leaves to the meristematic B in plant tissues were closely correlated with the content of sorbitol in the plant, and plants An increase in the proportion of boron allocated www.plantphysiol.org /cgi/content/full/119/2/735   (3244 words)

The World Market for D-Glucitol (Sorbitol): A 2005 Global Trade Perspective I have developed a methodology, based on macroeconomic and trade models, to estimate the market for d-glucitol (sorbitol) for those countries serving the world market via exports or supplying from various countries via imports. The total level of imports and exports on a worldwide basis, and those for each region, is based on a model which aggregates across over 150 key country markets and projects these to the current year. In such cases, the difference between the numbers given in this report and the numbers actually observed might be interpreted as the "net loss" or "net gain" due to these exogenous events affecting regular trade flows that would have occurred had these events not have taken place. www.mindbranch.com /listing/product/R307-7434.html   (820 words)

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