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Topic: Specific activity


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In the News (Thu 10 Dec 09)

  
 Task-Specific Neural Activity in the Primate Prefrontal Cortex - Asaad, Rainer, Miller (ResearchIndex)
Task-specific neural activity in the primate prefrontal cortex.
Task-Specific Neural Activity in the Primate Prefrontal Cortex (2000)
15 Activity of neurons in anterior inferior temporal cortex dur..
citeseer.ist.psu.edu /asaad00taskspecific.html   (445 words)

  
 Cell Type and Gene-specific Activity of the Retinoid Inverse Agonist AGN 193109: Divergent Effects from Agonist at Retinoic Acid Receptor {{gamma}} in Human Keratinocytes -- Thacher et al. 10 (4): 255 -- Cell Growth & Differentiation
The receptor specificity of MRP-8 down-regulation in NHKs was
TGase activity in detergent extracts of the cell particulate fraction is presented relative to untreated control.
AGN 193109 on MRP-8 is cell type specific.
cgd.aacrjournals.org /cgi/content/full/10/4/255   (4960 words)

  
 Dorlands Medical Dictionary
the catalytic effect exerted by an enzyme, expressed as units per milligram of enzyme (specific activity) or as molecules of substrate transformed per minute per molecule of enzyme (molecular activity).
continuous irregular slow activity that is variable in duration and amplitude and may change little with sleep or other physiological alterations; it may be related to deafferentation of an area of the cortex, to metabolic factors, or to the presence of subcortical cerebral lesions and tumors.
slow, paroxysmal, relatively constant delta activity seen on the electroencephalogram, associated frequently with metabolic disorders or diffuse encephalopathies and sometimes with subfrontal, deep midline, or posterior fossa lesions; it may be stronger occipitally in children and frontally in adults.
www.mercksource.com /pp/us/cns/cns_hl_dorlands.jspzQzpgzEzzSzppdocszSzuszSzcommonzSzdorlandszSzdorlandzSzdmd_a_12zPzhtm   (2462 words)

  
 Specific activity
Pm activity represents 928 Ci, and the specific activity of pure Pm-147 is 928 Ci/g.
Once you have this information it is a simple matter to calculate the activity in one drop, assuming you have a reasonable estimate of the mass or volume of the drop of solution.
Specific facts and circumstances may alter the concepts and applications of materials and information described herein.
www.hps.org /publicinformation/ate/q4423.html   (499 words)

  
 Specific activity - Wikipedia, the free encyclopedia
Specific activity is the amount of product formed by an enzyme in a given amount of time under given conditions per milligram of enzyme.
This page was last modified 23:09, 9 February 2006.
en.wikipedia.org /wiki/Specific_activity   (60 words)

  
 Mutations That Confer Resistance to 2-Deoxyglucose Reduce the Specific Activity of Hexokinase from Myxococcus xanthus -- Youderian et al. 181 (7): 2225 -- The Journal of Bacteriology
The hex mutations decrease the specific activity of a soluble hexokinase from M.
Hexokinase activities were determined by using the coupled reaction of Fraenkel and Horecker (12), with minor modifications.
Activities of hexokinase are plotted as a function of total protein in extracts prepared from wild-type M.
jb.asm.org /cgi/content/full/181/7/2225   (6893 words)

  
 Stage-Specific Activity of Pentavalent Antimony against Leishmania donovani Axenic Amastigotes -- Ephros et al. 43 (2): 278 -- Antimicrobial Agents and Chemotherapy
Biochemical mechanisms of the antileishmanial activity of sodium stibogluconate.
SbV is 73- to 271-fold, indicating that the activity of SbIII
After ~2 weeks, the parasites were incubated and were assayed for ODC activity.
aac.asm.org /cgi/content/full/43/2/278   (2908 words)

  
 Long-Term Exposure to Ozone Increases Acute Pulmonary Centriacinar Injury by 1-Nitronaphthalene: I. Region-Specific Enzyme Activity -- Paige et al. 295 (3): 934 -- Journal of Pharmacology And Experimental Therapeutics
The results of the activity assays indicated a possible increase in CYP 2B protein expression in the distal lung subcompartment.
For P450 2B and reductase activity measurements, liver samples and blood vessels consisting of arteries and veins throughout the lung also were collected for microsome preparation.
Information on the impact of ozone exposure on cytochrome P450 activity in the lung is complex and difficult to interpret.
www.jpet.org /cgi/content/full/295/3/934   (4877 words)

  
 The antiestrogen LY117018 blocks effects of estradiol on pituitary glucose-6-phosphate dehydrogenase specific activity and on serum LH.
The antiestrogen LY117018 blocks effects of estradiol on pituitary glucose-6-phosphate dehydrogenase specific activity and on serum LH.Neuroendocrine effects of the antiestrogen LY117018 were investigated in C57BL/6J mice.
A series of subcutaneous injections of 17 beta-estradiol (E2) into ovariectomized mice increased pituitary glucose-6-phosphate dehydrogenase (G6PDH) specific activity, increased uterine wet weight, and suppressed the postovariectomy rise in serum LH.
Simultaneous administration of LY117018 completely reversed the effects of E2 on G6PDH activity and uterine weight, and partially reversed the negative feedback of E2 on luteinizing hormone (LH).
www.pdg.cnb.uam.es /UniPub/iHOP/gp/4965387.html   (150 words)

  
 Tissue-Specific Transcriptional Activity of a Pancreatic Islet Cell-Specific Enhancer Sequence/Pax6-Binding Site Determined in Normal Adult Tissues in Vivo Using Transgenic Mice -- Beimesche et al. 13 (5): 718 -- Molecular Endocrinology
Verweij CL, Guidos C, Crabtree GR 1990 Cell type specificity and activation requirements for NFAT-1 (nuclear factor of activated T-cells) transcriptional activity determined by a new method using transgenic mice to assay transcriptional activity of an individual nuclear factor.
For each independent transgenic line, luciferase activity measured in the tissue with highest activity is set as 100 and luciferase activity measured in the other tissues is expressed relative to that.
Specific complexes formed by Pax6 and Pax6–5a are indicated by arrows on the left and right, respectively.
mend.endojournals.org /cgi/content/full/13/5/718   (5607 words)

  
 Structure and Specific Activity of Macrophage-Stimulating Lipopeptides from Mycoplasma hyorhinis -- Mühlradt et al. 66 (10): 4804 -- Infection and Immunity
mol, and hence the specific activity of this lipopeptide is 3.3
specific activity of MDHM to the unusual fatty acid content of
Induction of antitumor activity in macrophages by mycoplasmas in concert with interferon.
iai.asm.org /cgi/content/full/66/10/4804   (4972 words)

  
 Sentinel Node Mapping Identifies Vaccine-Draining Lymph Nodes With Tumor-Specific Immunological Activity -- Chin and Bear 9 (1): 94 -- Annals of Surgical Oncology
Activation and growth of murine tumor-specific T-cells which have in vivo activity with bryostatin 1.
In vitro antitumor activity of tumor-infiltrating lymphocytes expanded in recombinant interleukin-2.
Specificity of adoptive immunotherapy (AIT) effect: treatment of 4T07 flank tumors with popliteal isosulfan blue-stained draining lymph node (SDLN) or blindly collected draining lymph node (BDLN) lymphocytes from either Meth A- or 4T07-sensitized mice.
www.annalssurgicaloncology.org /cgi/content/full/9/1/94   (3648 words)

  
 Isolation of mouse THP gene promoter and demonstration of its kidney-specific activity in transgenic mice -- Zhu et al. 282 (4): 608 -- AJP - Renal Physiology
In vivo activity of the 5'-flanking region of the mouse THP gene.
inhibitory activity is larely attributed to the oligosaccharid
Tissue-specific expression of Tamm-Horsfall protein (THP) gene in the mouse.
ajprenal.physiology.org /cgi/content/full/282/4/F608   (5382 words)

  
 Genotype/Phenotype Correlations for Coagulation Factor XIII: Specific Normal Polymorphisms Are Associated With High or Low Factor XIII Specific Activity -- Anwar et al. 93 (3): 897 -- Blood
The FXIII specific activity was calculated for all the individuals studied.
FXIII activity, levels, and specific activity (SA) within the normal study population.
FXIII activity was determined using a modification of the fibrinogen and biotinylcadaverine assay described previously.
www.bloodjournal.org /cgi/content/full/93/3/897   (5432 words)

  
 Oxfam's Cool Planet for teachers - Tsunami in Asia - Index page
However, if you are talking about the tsunami in the classroom for the first time, it is important to bear in mind the effects of the disaster and subsequent media coverage on your pupils, and we recommend that you give pupils the opportunity to talk openly about their own feelings.
The following activities are designed to support you in exploring with pupils the impact of the Indian Ocean tsunami on communities in the affected regions.
If you are revisiting issues raised by the tsunami and exploring the situation a couple of months on, you may want to allow pupils to talk about their feelings again and ask them whether their feelings about the disaster have changed, and if so, why.
www.oxfam.org.uk /coolplanet/teachers/tsunami/index.htm   (959 words)

  
 Interrenal steroid 21-hydroxylase in eels: primary structure, progesterone-specific activity and enhanced expression by ACTH -- Li et al. 31 (2): 327 -- Journal of Molecular Endocrinology
Interrenal steroid 21-hydroxylase in eels: primary structure, progesterone-specific activity and enhanced expression by ACTH
Functional expression of the cDNA clone in non-steroidogenic COS-1 cells produced a protein with high 21-hydroxylase activity to convert progesterone to 11-deoxycortisterone but not 17alpha-hydroxyprogesterone to 11-deoxycortisol, although the latter is a preferred substrate for mammalian P450c21.
To examine whether 21-hydroxylated progesterone is actually 17alpha-hydroxylated in the eel interrenal, 11-deoxycorticosterone and (3)H-corticosterone were respectively incubated with the interrenal-containing anterior quarter of the head kidney.
dx.doi.org /10.1677/jme.0.0310327   (413 words)

  
 The Dual Nature of Specific Immunological Activity of Tumor-derived gp96 Preparations -- Chandawarkar et al. 189 (9): 1437 -- The Journal of Experimental Medicine
Specificity of gp96-elicited tumor immunity, regardless of the route of immunization.
In earlier studies demonstrating the specific immunogenicity of the cognate tumor-derived HSP-gp96 (2), it was noted that
As higher than optimal doses of gp96 did not immunize, it was difficult to assess the antigen specificity of this nonresponse.
www.jem.org /cgi/content/full/189/9/1437   (3787 words)

  
 Consequences of the Discoveries
The blue color reveals the specific activity of two homeotic genes in mouse embryos.
In figure A the HOX-D 2 gene is active earlier and nearer the embryo's head-end than the HOX-D 4 gene shown in figure B. In both cases there is a razor-sharp boundary at the upper end of the segment wheras gene activity is more diffuse further down.
www.nobel.se /medicine/laureates/1995/illpres/consequences.html   (438 words)

  
 PU.1/Spi-1 Is Essential for the B Cell-Specific Activity of the Mouse CD72 Promoter -- Ying et al. 160 (5): 2287 -- The Journal of Immunology
was specifically inhibited by the anti-PU.1 antiserum (Fig.
Specific expression of a tyrosine kinase gene, blk, in B lymphoid cells.
The relative luciferase activity is expressed as fold activity above the background conferred by the promoterless control plasmid.
www.jimmunol.org /cgi/content/full/160/5/2287   (6374 words)

  
 IE Circular No. 78-03, Packaging Greater than Type a Quantities of Low Specific Activity Radioactive Material for Transport
Specifically, 49 CFR 173.392 authorizes the shipment of LSA material in "strong, tight packages" when transported in vehicles assigned for the sole use of the consignor.
DOT regulations make no mention of the total activity that may be shipped in this manner.
The general license of 10 CFR 71.12 has requirements for the type of container when more than a Type A quantity of radioactive material is to be transported.
www.nrc.gov /reading-rm/doc-collections/gen-comm/circulars/1978/cr78003.html   (455 words)

  
 Cloning of Rabbit TR4 and Its Bone Cell-Specific Activity to Suppress Estrogen Receptor-Mediated Transactivation -- Harada et al. 139 (1): 204 -- Endocrinology
Because this repressive activity of TR4 was dose-dependent (Fig.
One microgram of total RNA was reverse-transcribed, and PCR was performed for 35 cycles with primers specific to these two forms of TR4 (TR4–0 as upper band and TR4–1 as lower band) as described in Materials and Methods.
One microgram of total RNA was reverse-transcribed, and PCR was performed for 35 cycles with primers specific to these two forms of TR4 (TR4–0 as upper band and TR4–1 as lower band) as described in Fig.
endo.endojournals.org /cgi/content/full/139/1/204   (4730 words)

  
 High specific activity heme-Fe and its application for studying heme-Fe metabolism in Caco-2 cell monolayers -- Follett et al. 283 (5): 1125 -- AJP - Gastrointestinal and Liver Physiology
High specific activity heme-Fe and its application for studying heme-Fe metabolism in Caco-2 cell monolayers -- Follett et al.
is the synthesis of high specific activity radiolabeled heme.
High specific activity heme-Fe and its application for studying heme-Fe metabolism in Caco-2 cell monolayers
ajpgi.physiology.org /cgi/content/full/283/5/G1125   (5004 words)

  
 Subcellular Targeting of Methylmercury Lyase Enhances Its Specific Activity for Organic Mercury Detoxification in Plants -- Bizily et al. 131 (2): 463 -- PLANT PHYSIOLOGY
specific activities (enzyme activity per unit of protein) of the
The relative specific activities were obtained by dividing the volatilization rate by the relative protein level.
The enzyme activity [nanograms of Hg(0) per minute per gram plant tissue [fresh weight]) for each line is reported as the average of three separate assays with 10 seedlings each and the
www.plantphysiol.org /cgi/content/full/131/2/463   (5134 words)

  
 The Hindu : Business : Sensex drops 22 points in scrip-specific activity
Equities once again witnessed erratic movements after a firm start and the Sensex ended down by 22 points in scrip-specific activity despite the hike in foreign direct investment cap in telecom sector to 74 per cent and upgradation of India's long-term foreign currency rating by Standard & Poor's.
After early signs of a rally, the BSE benchmark 30-share index later came under pressure and fluctuated between 6600.25 and 6509.92 before ending the day at 6530.06 against yesterday's close of 6552.47, a net fall of 22.41 points.
Republication or redissemination of the contents of this screen are expressly prohibited without the written consent of The Hindu
www.hindu.com /2005/02/03/stories/2005020304751800.htm   (282 words)

  
 CCAAT-Enhancer-binding Proteins (C/EBP) Regulate the Tissue Specific Activity of the CD11c Integrin Gene Promoter Through Functional Interactions with Sp1 Proteins -- López-Rodríguez et al. 272 (46): 29120 -- Journal of Biological Chemistry
P]dCTP to an specific activity of approximately 10
The differential occupancy of the CEBP-80 element suggested that it might contribute to the tissue specific activity of the
activity of the same construct cotransfected with the empty vector.
www.jbc.org /cgi/content/full/272/46/29120   (5133 words)

  
 Johns Hopkins Vasculitis Center Research Birmingham Vasculitis Activity Score
It is important to remember that Persistent activity is activity, not damage.
Sometimes it may be difficult to be certain whether a symptom or sign is due to Persistent activity or to damage.
Damage, defined as the presence of non-healing scars, and is a concept distinct from current disease activity.
vasculitis.med.jhu.edu /research/bvas.html   (1134 words)

  
 Optimized expression and specific activity of IL-12 by directed molecular evolution -- Leong et al. 100 (3): 1163 -- Proceedings of the National Academy of Sciences
exhibited a concomitant 10-fold increase in the specific activity
Optimized expression and specific activity of IL-12 by directed molecular evolution -- Leong et al.
Optimized expression and specific activity of IL-12 by directed molecular evolution
www.pnas.org /cgi/content/full/100/3/1163   (4495 words)

  
 Characterization of Fus3 Localization: Active Fus3 Localizes in Complexes of Varying Size and Specific Activity -- Choi et al. 10 (5): 1553 -- Molecular Biology of the Cell
Gradient density centrifugation was used in parallel to high-speed fractionation to determine the relative specific activity
The activity of Fus3 is tightly regulated, presumably because inappropriate activation would block vegetative growth.
Bardwell, L., Cook, J.G., Chang, E.C., Cairns, B.R., and Thorner, J. Signaling in the yeast pheromone response pathway: Specific and high-affinity interaction of the mitogen-activated protein (MAP) kinases Kss1 and Fus3 with the upstream MAP kinase kinase Ste7.
www.molbiolcell.org /cgi/content/full/10/5/1553   (7681 words)

  
 Covert Visual Attention Modulates Face-Specific Activity in the Human Fusiform Gyrus: fMRI Study -- Wojciulik et al. 79 (3): 1574 -- Journal of Neurophysiology
The present study tested whether face-specific activity in the human fusiform gyrus is reduced for stimuli presented outside
activity is reduced when faces are presented outside the focus
activity is reduced when stimuli appear outside (vs. inside) the
jn.physiology.org /cgi/content/full/79/3/1574   (3409 words)

  
 Synergism with germ line transcription factor Oct-4: viral oncoproteins share the ability to mimic a stem cell-specific activity.
The adenovirus E1A protein can mimic the activity of this stem cell-specific factor and stimulates Oct-4 activity in differentiated cells.
Furthermore, we demonstrate that, like E1A, the human papillomavirus E7 oncoprotein also specifically binds to the Oct-4 POU domain.
Here we characterize the Oct-4-E1A interaction and show that the E1A 289R protein harbors two independent Oct-4 binding sites, both of which specifically interact with the POU domain of Oct-4.
www.pdg.cnb.uam.es /UniPub/iHOP/gp/1796443.html   (189 words)

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