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Topic: Spectrometry

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	Mass spectrometry - Wikipedia, the free encyclopedia
		Mass spectrometry is an analytical technique used to measure the mass-to-charge ratio of ions.
		Other types of mass spectrometry data are well represented as a contour map of mass-to-charge on one axis, intensity on another and an additional experimental parameter (often time) on the third axis, thus producing a three dimensional surface.
		Pharmacokinetics is often studied using mass spectrometry due to the complex nature of the matrix (often blood or urine) and the need for high sensitivity to observe low dose and long time point data.
	en.wikipedia.org /wiki/Mass_spectrometry (4965 words)

	Archaeology Wordsmith
		The results are generally more accurate than those obtained using optical emission spectrometry and the technique's use will probably increase, especially for the identification of sources of metal ores through the recognition and quantification of the trace elements.
		The wavelengths, separated by the use of a prism or diffraction grating, are each characteristic of individual elements, and the intensity of the light of particular wavelengths indicates the concentration of each element.
		X-ray emission spectrometry is the group of analytical methods in which emitted X-ray radiation is monitored.
	www.reference-wordsmith.com /cgi-bin/lookup.cgi?category=&where=headword&terms=spectrometry (801 words)

	[No title] (Site not responding. Last check: 2007-11-01)
		Mass spectrometry is a technique for separating ions by their mass-to-charge (m/z) ratios.
		Two techniques which are often used with biological samples include electrospray ionization (for which John Fenn received the Nobel Prize in Chemistry in 2002) and Matrix-assisted Laser Desorption Ionization (MALDI) (for which Koichi Tanaka received the Nobel at the same time).
		Fourier Transform Mass Spectrometry uses perturbations in magnetic fields to measure m/z values extremely accurately.
	www.wikiwhat.com /encyclopedia/m/ma/mass_spectrometry.html (317 words)

	Mass spectrometry analysis of peptides
		The protein is digested with trypsin in the gel, peptides eluted and fractionated by reverse phase chromatography and introduced into the mass spectrometer.
		Mass spectrometry determines protein and peptide masses more accurately than gel filtration or gel electrophoresis in part because the mass is measured more directly than with other techniques; for example, the mass of a peptide with a size of 2000 can be determined with an accuracy of 0.2 mass units.
		Identification of phosphorylation sites by mass spectrometry without prior knowledge of the site is expected has a 1 in 10 chance of success.
	www.healthsystem.virginia.edu /internet/biomolec/mass_spectrometry.cfm (954 words)

	Amazon.fr : Mass Spectrometry Of Inorganic, Coordination and Organometallic Compounds: Tools - Techniques - Tricks: ... (Site not responding. Last check: 2007-11-01)
		Mass spectrometry is one of the many powerful instrumental techniques that are available to the inorganic, coordination or organometallic chemist.
		While mass spectrometry as applied to the analysis of inorganic substances has a long history, it has been the relatively recent introduction of the soft ionisation techniques of ESI (electrospray ionisation) and to a lesser extent, MALDI (Matrix Assisted Laser Desorption Ionisation) that have revolutionised the field.
		These developments have turned mass spectrometry of inorganic and organometallic compounds on its head: once a slow, tedious technique that could be applied only to pure compounds, mass spectrometry is now at its most powerful and useful when applied to the rapid analysis of complex mixtures.
	www.amazon.fr /Spectrometry-Inorganic-Coordination-Organometallic-Compounds/dp/0470850167 (628 words)

	Team 17: Proteomic Mass Spectrometry
		Our group is taking advantage of technical and conceptual advances in biochemistry, molecular biology and mass spectrometry to develop integrated procedures for describing the interaction partners, modification features and changes in these protein properties introduced by stimulations.
		Mass spectrometry is highly sensitive and versatile for studying proteins.
		Mass spectrometry based methods are used to characterise protein interaction, modification and expression changes.
	www.sanger.ac.uk /Teams/Team17 (449 words)

	Amazon.ca: Applications of Inorganic Mass Spectrometry: Books: John R. de Laeter (Site not responding. Last check: 2007-11-01)
		Mass spectrometry is a powerful analytical technique used to identify unknown compounds, to quantify known materials, and to elucidate the structural and chemical properties of molecules.
		Inorganic mass spectrometry focuses on the analysis of metals and elements rather than organic compounds.
		Applications of Inorganic Mass Spectrometry describes developments in mass spectrometric instrumentation, together with applications in metrology, nuclear science, cosmochemistry, geoscience, environmental science, and planetary science.
	www.amazon.ca /Applications-Inorganic-Mass-Spectrometry-Laeter/dp/0471345393 (418 words)

	BTR Directory - Mass Spectrometry (Site not responding. Last check: 2007-11-01)
		The resource’s mission is to conduct high-sensitivity structural determinations and analyses of biological compounds via mass spectrometry (MS).
		An emphasis is on glycoconjugates, oligosaccharides, and proteins; and structure-activity studies related to immunology, carcinogenesis, developmental biology, parasitology, and infectious diseases; biophysical properties of carbohydrates and glycoconjugates; carbohydrate and amino acid sequence determinations of glycoproteins and proteins; and structure elucidation of unusual residues and posttranslational modifications.
		Publicly accessible mass spectrometry computer program/database is available at the website, along with a set of useful software tools (e.g., for protein identification spectrum manipulation, disulfide-mapping, etc.) that can access current information concerning any given protein or DNA sequence.
	www.ncrr.nih.gov /ncrrprog/btdir/MassSpec.asp (1905 words)

	Base Peak - Mass Spectrometry Groups
		Mass spectrometry at the University of Vermont and the stable isotope laboratory of Dwight Matthews.
		The Isotope Geochemistry Lab performs thermal ionization mass spectrometry for the analyses of Pb, Nd, and Sr isotopes and trace element concentration determinations by isotope dilution for geochemical investigation of the mantle, crust, and oceans.
		The mass spectrometry resource at Washington University-St. Louis is a merger of the former NSF Midwest Center for Mass Spectrometry (founded in 1978 at the University of Nebraska) and the Biomedical Mass Spectrometry Resource (founded in 1976 at Washington University).
	www.wiley.com /legacy/wileychi/ms/msi/msgroups.html (4816 words)

	Amazon.com: Mass Spectrometry for Chemists and Biochemists: Books: Robert A. W. Johnstone,Malcolm E. Rose (Site not responding. Last check: 2007-11-01)
		The authors discuss powerful methods combining mass spectrometry with newer separation techniques, the increased use of computers, and analysis of once difficult polar and large-mass compounds such as proteins using new ionization methods.
		The book, requiring no previous knowledge of mass spectrometry, is an ideal teaching text at both the undergraduate and postgraduate level, and will also be of considerable interest to research workers.
		The basis of mass spectrometry is the production of ions from neutral compounds and, particularly in chemistry and biochemistry, the examination of the subsequent decomposition of those ions.
	www.amazon.com /Spectrometry-Chemists-Biochemists-Robert-Johnstone/dp/0521424976 (697 words)

	Mass Spectrometry: A foundation course
		Mass Spectrometry: A Foundation Course is a textbook covering the field of mass spectrometry across the chemical, physical, biological, medical and environmental sciences.
		Dedicated chapters are included on: organic mass spectrometry; ion chemistry - to emphasise the role of mass spectrometry in fundamental chemistry and physics; biological mass spectrometry including proteomics; mass spectrometry in medicine, environmental and surface science and accelerator mass spectrometry, to emphasise the importance of these areas.
		Highly readable, easy-to-use and logically presented, Mass Spectrometry: A Foundation Course is an ideal text for students and for those who work with mass spectrometers who wish to gain a solid understanding of the basics in modern mass spectrometry.
	www.rsc.org /Publishing/Books/0854046097.asp (367 words)

	Real-Time Single Particle Mass Spectrometry Database (Site not responding. Last check: 2007-11-01)
		Silva, Philip J. and Prather Kimberly A. Interpretation of Mass Spectra from Organic Compounds in Aerosol Time-of-Flight Mass Spectrometry.
		Proceedings of the 46th ASMS Conference on Mass Spectrometry and Allied Topics 375.
		Laser Desorption Mass Spectrometry of a Levitated Single Microparticle in a Quadrupole Ion Trap.
	www.udel.edu /chem/johnston/SPMSdbase.html (2778 words)

	Biopharmaceutical Mass Spectrometry glossary
		Mass Spectrometry for Protein Biomarker Discovery Will provide an in-depth update on the state- of- the- art technologies and experimental design when using MS for protein biomarker discovery and profiling.
		Arrangement in which ions with a desired range of quotients mass/charge are first made to describe stable paths under the effect of a high- frequency electric quadrupole field, and are then separated and presented to a detector by adjusting the field so as to selectively induce path instability according to their respective mass/charge ratios.
		Matrix Assisted Laser Desorption Ionization-Time of Flight mass spectrometry: With MALDI-TOF (matrix- assisted laser desorption- ionization time- of- flight) mass spectrometry, a laser beam passes through the substances to be analyzed, and the laser causes these elements to vaporize and their molecules to fly upward into a tube.
	www.genomicglossaries.com /content/mass_spectrometry.asp (3198 words)

	Intute: Science, Engineering and Technology - FE Subject Pack - MASS SPECTROMETRY (Site not responding. Last check: 2007-11-01)
		The Little Encyclopedia of Mass Spectrometry was developed by the Mass Spectrometry Group of the University of Heidelberg, and is intended to serve as a fast source of basic knowledge of mass spectrometry.
		It includes: an introduction to how the mass spectrometer works and how a mass spectrum is produced; information which can be obtained from the mass spectrum of an element; and the mass spectra of organic compounds (fragmentation patterns, molecular ion peaks, spectra of organic compounds containing halogen atoms).
		It covers subjects such as uses of mass spectrometry, history of mass spectrometry, what a mass spectrometer is, examples of a mass spectrum, how the analyser and detector work, quantitative analysis and elemental mass spectroscopy.
	www.intute.ac.uk /sciences/education/fe/mass_spectrometry.html (547 words)

	HXMS.com \|\| Mass Spectrometry
		Mass spectrometry is invaluable for measuring the molecular weight of proteins.
		It is for these reasons that we wish to use mass spectrometry to investigate the incorporation of hydrogen into proteins during hydrogen exchange.
		MALDI (matrix assisted laser desorption mass spectrometry) uses a laser beam to zap crystallized protein/matrix mixtures into the gas phase.
	www.hxms.com /ms.htm (401 words)

	Peptide and Protein Characterization with Mass Spectrometry (Site not responding. Last check: 2007-11-01)
		Protein chemists who are new to mass spectrometry or are considering LC/MS or MALDI will benefit from this introduction to the technique.
		Obtain an overview of mass spectrometry fundamentals plus the operational specifics of mass analyzers and LC/MS and MALDI sample introduction systems employed for protein analysis.
		Mass Spectrometry Fundamentals -- atoms, molecules, ions; the mass spectrum; isotopes and their importance in MS; fragmentation and interpretation in MS.
	www.chemistry.org /portal/a/c/s/1/acsdisplay.html?DOC=education\professional\scsp17.html (581 words)

	Mass Spectrometry - RTI International
		Mass spectrometry (MS) is a powerful analytical technique used to identify unknown compounds, quantify known materials, and determine the structural and chemical properties of molecules.
		Mass spectrometers are frequently coupled with state-of-the-art separation techniques, such as gas chromatography/mass spectrometry (GC/MS) or liquid chromatography/mass spectrometry (LC/MS), to allow accurate determination of very low levels of a compound in biological fluids or other complex matrices.
		RTI's mass spectrometry (MS) facility represents a coordinated accumulation of instruments to meet current needs for sensitive, specific, and quantitative analysis of biological or environmental compounds.
	www.rti.org /page.cfm?nav=316 (555 words)

	UNDSMHS \| Mass Spectrometry
		he Mass Spectrometry facility at the University of North Dakota School of Medicine and Health Sciences was opened in the spring of 2003.
		The facility provides instrumentation, expertise and training in mass spectrometry necessary for the advancement of COBRE research projects.
		The Proteomics/Mass Spectrometry Core Laboratory is located on the UND campus in the School of Medicine and Health Sciences building (r.
	www.med.und.nodak.edu /cobre/mass_spec (133 words)

	MASS SPECTROMETRY - Under Construction - Personal (Site not responding. Last check: 2007-11-01)
		The aim of the Society is to promote mass spectrometry by providing contact with local and international leaders in all areas, and providing a forum, through its meetings, for the presentation of research in mass spectrometry and related disciplines.
		Its aims are to encourage participation in all aspects of mass spectrometry on the widest basis, to promote knowledge and advancement in the field and to provide a forum for the exchange of views and information.
		A peptide-mass fingerprinting tool from the UCSF Mass Spectrometry Facility that tries to fit a user's mass spectrometry data to a protein sequence in an existing database and thus predict the identity of the user's protein.
	maxpages.com /rafikmomin/MS - !http://maxpages.com/rafikmomin/MS (1275 words)

	Mass Spectrometry Resource
		he BUSM Mass Spectrometry Resource is engaged in the development and application of mass spectral methods for biology and medicine with primary emphasis on studies of oligosaccharides and glycoconjugates.
		he mission of the Boston University Mass Spectrometry Resource for Biology and Medicine is to pursue sophisticated mass spectrometry in an environment with close interaction with life scientists and physicians.
		The BUSM Mass Spectrometry Resource is located on the 5th floor of 670 Albany St. The building is located behind 700 Albany St. (The CABR Building), see the Campus Map.
	www.bumc.bu.edu /msr (218 words)

	Mass Spectrometry Facility (Site not responding. Last check: 2007-11-01)
		In addition to the mass spectral service, we are working on a variety of research projects including various fields in gas phase ion/neutral chemistry, proteomics, and mass spectrometry of polymers.
		It is used for recording metastable ion and collision-induced dissociation mass spectra of mass-selected ions.
		A variety of tandem mass spectrometry experiments can be performed with ions produced by ESI and APCI methods.
	www.rpi.edu /dept/chem/facilities/massspec.html (460 words)

	Mauritz - MALDI-TOF Mass Spectrometry
		The powerful capabilities of Matrix Assisted Laser Desorption/Ionization Time-of-Flight (MALDI-TOF) Mass Spectrometry are realized with the fast and accurate determination of molar masses, the sequencing of repeat units, and recognition of polymer additives and impurities.
		Mass Spectrometry (MS) has been appropriately used for the analysis of molar masses of molecules for the past 50 years 1.
		MALDI-TOF mass spectrometry is an emerging technique offering promise for the fast and accurate determination of a number of polymer characteristics.
	www.psrc.usm.edu /mauritz/maldi.html (2520 words)

	Mass Spectrometry
		Mass Spectrometry: (new) the measurement of ion mass to charge ratios (m/z) usually by direct amplification of ion signals.
		The combined use of a laser and added solute, usually a crystalline organic acid with an absorption near the wavelength of the laser which when cocrystallized with analyte assists in the ionization and desorption process.
		Tandem Mass Spectrometry: a sophisticated form of mass analysis whereby ions separated according to their m/z value in the first stage analyzer are selected for fragmentation and the fragments analyzed in a second analyzer.
	www.cco.caltech.edu /~ppmal/sample_prep/term_def.html (1718 words)

	- Thermo Electron Corporation - Breakthrough Mass Spectrometry Technology (Site not responding. Last check: 2007-11-01)
		Thermo unveils several new technological advancements in mass spectrometry.
		Most significant is the launch of the LTQ Orbitrap™, a hybrid mass spectrometer that, compared to existing Time-of-Flight (TOF) technology, offers superior mass resolution and accuracy, detection power and dynamic range.
		The LTQ Orbitrap's patented technology represents possibly the most significant breakthrough in mass spectrometry since the introduction of the ion trap mass spectrometer over 20 years ago.
	www.thermo.com /com/cda/newsevents/news_detail/1,5588,11759,00.html (442 words)

	Mass Spectrometry (MS) Systems by Varian, Inc. (Site not responding. Last check: 2007-11-01)
		Varian's robust Mass Spectrometry (MS) systems are designed to meet your immediate needs for sensitivity, precision, and sample throughput.
		Varian's worldwide technical support team is ready to assist you with all of your Mass Spectrometry support and service needs.
		Be sure to check out the Mass Spectrometry Applications Notes for the latest information on analysis and detection techniques.
	varianinc.com /cgi-bin/nav?varinc/docs/products/mass_spec/index&... (171 words)

	Liquid Chromatography/Mass Spectrometry; A New Analytical Capability Research Brief
		Liquid chromatography coupled with mass spectrometry permits the analysis of species that are thermally labile, polar, or not volatile enough to be analyzed by gas chromatography coupled with mass spectrometry.
		When this sample is analyzed by gas chromatography couple with mass spectrometry resulted in no signal in the detector.
		The liquid chromatograph coupled with mass spectrometry provides expanded analytical capability for the identification of unknown organic and inorganic species in a wide variety of samples.
	www.sandia.gov /materials/sciences/factsheets/LiqChrom.html (292 words)

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