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Topic: Spironolactone

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	Spironolactone - Wikipedia, the free encyclopedia
		Spironolactone (marketed as Aldactone®, Novo-Spiroton®, Spiractin®, Spirotone®, or Berlactone®) is a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat low-renin hypertension, hypokalemia, and Conn's syndrome.
		Spironolactone inhibits the effect of aldosterone by competing for intracellular aldosterone receptor in the distal tubule cells.
		Spironolactone is associated with an increased risk of bleeding from the stomach and duodenum, but a causal relationship between the two has not been established.
	en.wikipedia.org /wiki/Spironolactone (614 words)

	spironolactone (Aldactone) - drug class, medical uses, medication side effects, and drug interactions by MedicineNet.com
		Therefore, spironolactone is classified as a potassium-sparing medication that promotes the output of urine (diuretic).
		PRESCRIBED FOR: Spironolactone is used as a diuretic to remove the excess fluid caused by congestive heart failure, cirrhosis of the liver, and kidney disease.
		Therefore, spironolactone usually is not administered with other agents that can raise blood potassium levels, such as potassium supplements, ACE inhibitors, indometacin (Indocin), or other potassium-sparing diuretics.
	www.medicinenet.com /spironolactone/article.htm (435 words)

	MedlinePlus Drug Information: Spironolactone
		Spironolactone is used to treat certain patients with hyperaldosteronism (the body produces too much aldosterone, a naturally occurring hormone); low potassium levels; and in patients with edema (fluid retention) caused by various conditions, including heart, liver, or kidney disease.
		Spironolactone is also used alone or with other medications to treat high blood pressure.
		Spironolactone also may be used to treat certain female patients with abnormal facial hair.
	www.nlm.nih.gov /medlineplus/druginfo/medmaster/a682627.html (935 words)

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