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Topic: Splenectomy

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	Splenectomy
		Splenectomy is the surgical removal of the spleen, which is an organ that is part of the lymphatic system.
		The decision to perform a splenectomy depends on the severity and prognosis of the disease that is causing the hypersplenism.
		Laparoscopic splenectomy is gaining increased acceptance in the early 2000s as an alternative to open splenectomy for a wide variety of disorders, although splenomegaly still presents an obstacle to laparoscopic splenectomy; massive splenomegaly has been considered a contraindication.
	www.healthatoz.com /healthatoz/Atoz/ency/splenectomy.jsp (2004 words)

	CLL Topics: Splenectomy
		The role of splenectomy for lymphoproliferative and myeloproliferative malignancies is complex and sometimes controversial.
		Although splenectomy is helpful in the management of selected patients with chronic lymphocytic leukemia (CLL), in most cases this procedure is accompanied by a greater morbidity and mortality, mainly due to sepsis.
		The good results obtained with subtotal splenectomy in the present case indicate that this procedure may be a new alternative for the treatment of CLL when removal of the spleen is indicated.
	www.clltopics.org /Complications/Splenectomy.htm (2325 words)

	MedlinePlus Medical Encyclopedia: Spleen removal
		All patients undergoing splenectomy should be vaccinated against pneumococcal pneumonia.
		However, any patients who have had a splenectomy should seek medical attention for even seemingly minor illnesses, such as sinus infections or sore throats, as the health care provider may wish to prescribe antibiotics.
		Hospitalization is usually less than a week (1-2 days for laparoscopic splenectomy), and complete healing should occur within 4 to 6 weeks.
	www.nlm.nih.gov /medlineplus/ency/article/002944.htm (526 words)

	Splenectomy Information on Healthline
		Splenectomy is the surgical removal of the spleen, which is an organ that is part of the lymphatic system.
		Splenectomy was once the only treatment for this disease; but due to the complications associated with splenectomy (low blood cell counts, fatigue, frequent infections, and easy bleeding or bruising), physicians are now more often recommending chemotherapy.
		Splenectomy does not cure myelofibrosis but may be performed to relieve pain caused by the swollen spleen.
	www.healthline.com /galecontent/splenectomy-1 (902 words)

	Splenectomy
		Splenectomy is the surgical removal of the spleen, which is an organ that is part of the lymphatic system.
		The decision to perform a splenectomy depends on the severity and prognosis of the disease that is causing the hypersplenism.
		Splenectomy is the definitive treatment for this disease and is effective in about 70% of chronic ITP cases.
	www.lifesteps.com /gm/Atoz/ency/splenectomy_pr.jsp (1760 words)

	Splenectomy - Wikipedia, the free encyclopedia
		A splenectomy is a procedure that involves the removal of the spleen by operative means.
		The spleen, similar in structure to a large lymph node, has historically held rather a mythical role but current knowledge of its purpose includes the destruction of old red blood cells and platelets and the detection and fight against certain bacteria.
		Following splenectomy, the platelet count may rise to high levels in blood leading to an increased risk of clot formation.
	en.wikipedia.org /wiki/Splenectomy (371 words)

	NGC - NGC Summary
		Splenectomy does not usually alter overall survival, and this information should be clearly discussed with the patient prior to operation, again with a hematologist/oncologist, including the probable requirement for blood or blood products.
		Less common indications for splenectomy include splenic abscesses, cysts, sinistral portal hypertension secondary to isolated splenic vein thrombosis or obstruction, or splenic mass presumed to be a primary or undiagnosed neoplasm.
		Splenectomy is occasionally included in en bloc resection for malignancy in an adjacent organ, such as the stomach, colon, adrenal gland, or pancreas.
	www.guideline.gov /summary/summary.aspx?doc_id=5505&nbr=3748&ss=6&xl=999 (1201 words)

	LLUCH pediatric surgery - splenectomy
		A splenectomy may be indicated in children for a variety of disorders.
		The major risk of splenectomy is overwhelming infection from a group of bacteria that are called "encapsulated" and are usually destroyed by the spleen.
		During laparoscopic splenectomy, four "stab" incisions between 1/4 and 1/2 inch in length are made in the abdominal wall.
	www.llu.edu /lluch/pedsurg/splenectomy.htm (1105 words)

	Splenectomy versus conservative management for acute sequestration crises in people with sickle cell disease
		Splenectomy and blood transfusion, with their consequences, are the mainstay of long-term management used in different parts of the world.
		To assess whether splenectomy (total or partial), to prevent acute splenic sequestration crises in people with sickle cell disease, improved survival and decreased morbidity in people with sickle cell disease, as compared with regular blood transfusions.
		There is a need for a well-designed, adequately-powered, randomized controlled trial to assess the benefits and risks of splenectomy compared to transfusion programmes, as a means of improving survival and decreasing mortality from acute splenic sequestration in people with sickle cell disease.
	www.cochrane.org /reviews/en/ab003425.html (500 words)

	SSAT - Physician Guidelines - Indications For Splenectomy (Site not responding. Last check: )
		Laparoscopic splenectomy, which is becoming increasingly common, appears to be safe and associated with less pain, lower hospital stay, and more rapid convalescence.
		Operative mortality for elective splenectomy is less than 1% except in patients with myeloproliferative disorders, who are at increased risk for postoperative hemorrhage.
		Postoperative complications of open splenectomy include wound infection, hernia formation, hemorrhage, subphrenic abscess, pancreatic pseudocyst (secondary to inadvertent injury to the tail of the pancreas), and gastric fistula/perforation (secondary to injury/necrosis of the gastric wall during ligation of the short gastric vessels).
	www.ssat.com /cgi-bin/spleen7.cgi?affiliation=other&referer= (1257 words)

	Some Unusual Indications Of Splenectomy
		Response to splenectomy was excellent in malignant histiocytosis, splenic hemiangioma and some of the parameters in hairy cell leukemia and Gaucher's disease, while as an unsatisfactory response was observed in tropical splenomegaly sydrome and in some of the parameters of hairy cell leukemia and Gaucher's disease.
		The first total splenectomy for disease is attributed to Adriano-Zaccarello in 1549, although it has been suggested that the excised viscus was an ovarian cyst, clark (1676) performed splenectomy in dogs with survival.
		To conclude, we are of the opinion that splenectomy still continues to be a gold standard in various cytopenias secondary to any common or rare disorder in patients where all other medical measures have failed provided there is an excellent co-operation and understanding between a hematologist and a surgeon.
	www.ispub.com /ostia/index.php?xmlFilePath=journals/ijs/vol7n2/splenectomy.xml (1995 words)

	SPLENECTOMY FOR HEMATOLOGICAL DISEASES: (Site not responding. Last check: )
		Splenectomy in these patients was beneficial in reducing their transfusion requirements and its attendant risks, eliminating the discomfort from mechanical pressure of the enlarged spleen, avoiding the risks of acute splenic sequestration crisis, and managing splenic abscess.
		For those with thalassemia, total splenectomy was beneficial in reducing their transfusion requirements, while partial splenectomy was beneficial only as a temporary measure, as regrowth of splenic remnant in these patients subsequently led to increase in their transfusion requirements.
		For the evaluation of the hematological response to splenectomy in hypersplenism, the pretransfusion level nearest to the date of splenectomy was taken as the preoperative value, and the mean of multiple estimations performed postoperatively and during outpatient follow-ups as the postoperative value.
	www.kfshrc.edu.sa /annals/194/98-301.html (3560 words)

	Laparoscopic Splenectomy
		Laparoscopic splenectomy is the surgical removal of the spleen.
		Laparoscopic splenectomy is a surgical technique used to remove the spleen without making a large incision.
		If you have any questions about the need for laparoscopic splenectomy, alternatives, procedure cost, insurance or billing, physician training and experience, or have questions about surgery, you are encouraged to ask the office or hospital staff and your physician.
	www.johnmuirhealth.com /index.php/laparoscopic_spleen.html (1165 words)

	UpToDate Indications for splenectomy in Felty's syndrome
		The hospitalization rate for splenectomy was 71 percent lower in 1998-2001 than in 1983-1987 [4].
		— Splenectomy is followed by a short-term increase in the absolute granulocyte count, often to the normal range, in more than 80 percent of patients with FS [1,5].
		However, the value of splenectomy in preventing serious infection and improving survival is unclear [1].
	patients.uptodate.com /print.asp?print=true&file=rheumart/13802 (486 words)

	Danbury Hospital: Laparoscopic Surgery: Splenectomy
		The spleen is normally found in the upper left corner of the abdominal cavity, protected by the lower ribs.
		Traditional surgery for splenectomy requires a large incision under the rib cage for exposure and safe removal.
		Since laparoscopic splenectomy entails breaking up the organ into smaller pieces, those that require a close pathologic examination need to be removed whole through a larger incision.
	www.danburyhospital.org /DH_surgery_layout.cfm?id=994 (534 words)

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