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Topic: Splenomegaly

	eMedicine - Splenomegaly : Article by Vikramjit S Kanwar, MBBS, MBA, MRCP(UK), FAAP
		Splenomegaly is the result of the accumulation of abnormal lipids in splenic macrophages.
		Splenomegaly is usually the result of systemic disease and not the result of primary splenic disease.
		Children with splenomegaly due to acute viral illness, particularly infectious mononucleosis, demonstrate great fragility of the spleen and are at risk of rupture even with modest degrees of splenomegaly.
	www.emedicine.com /ped/topic2139.htm (5004 words)

	Splenomegaly: Spleen Disorders: Merck Manual Professional
		Splenomegaly increases the spleen's mechanical filtering and destruction of RBCs and often of WBCs and platelets.
		Splenomegaly is the hallmark; spleen size correlates with the degree of anemia.
		Hypersplenism is suspected in patients with splenomegaly and anemia or cytopenias; evaluation is similar to that of splenomegaly (see Spleen Disorders: Splenomegaly).
	www.merck.com /mmpe/sec11/ch138/ch138b.html (985 words)

	Reference.com/Encyclopedia/Splenomegaly
		Splenomegaly is an enlargement of the spleen, which usually lies in the left upper quadrant (LUQ) of the human abdomen.
		Splenomegaly is usually associated with increased workload (such as in hemolytic anemias), which suggests that it is a response to hyperfunction.
		Patients with splenomegaly may present with abdominal pain, early satiety due to splenic encroachment, and may complain of the symptoms of anemia due to accompanying cytopenia.
	www.reference.com /browse/wiki/Hypersplenism (260 words)

	TheFetus.net - Cytomegalovirus, splenomegaly -Donna Chriss-Price, RT, RDMS, Sandra K. Lawrence, MD¶, Philippe Jeanty, ...
		We describe a case of isolated splenomegaly detected by sonography in a 36-week gestation fetus, which had antenatal laboratory confirmation of prenatal cytomegalovirus infection.
		The differential diagnosis of splenomegaly in an infant or fetus presents a puzzling diagnostic dilemma.
		Splenomegaly is usually secondary to systemic illness, signifying an abnormality of the lymphoid, reticuloendothelial, or vascular components of the spleen.
	www.thefetus.net /page.php?id=150 (2643 words)

	Enlarged Spleen in Ferrets
		Approximately 5% of all cases of splenomegaly are due to cancer.
		Splenomegaly is also seen in connection with infections of the stomach, especially with Helicobacter, and with dental disease.
		Splenomegaly resulting from hypersplenism is treated by surgical removal of the spleen.
	www.peteducation.com /article.cfm?cls=11&cat=1289&articleid=2431 (619 words)

	Splenomegaly in sarcoidosis: a report of 16 cases.
		Splenomegaly in sarcoidosis: a report of 16 cases.
		In a previous study, we reported that splenomegaly was associated with a poor outcome of the disease.
		The results of this study disclosed that patients with splenomegaly had evidence of extensive pulmonary and extrathoracic sarcoidosis with a poor prognosis in spite of steroid therapy.
	www.galenicom.com /medline/article/8532960/jo:0393-1447 (221 words)

	Splenomegaly - Evanston Northwestern Healthcare (Site not responding. Last check: )
		The spleen is an organ involved in the production and maintenance of red blood cells, the production of certain circulating white blood cells, and is a part of the lymph system and the immune system.
		Because of its wide variety of functions, the spleen may be affected by many conditions involving the blood or lymph system, and by infection, malignancies, liver disease, and parasites.
		Rupture of the enlarged spleen is particularly possible in infectious mononucleosis and several other causes of splenomegaly.
	www.enh.org /HealthAndWellness/Encyclopedia/ency/article/003276.aspx (432 words)

	Splenomegaly: Symptom Causes - WrongDiagnosis.com
		Splenomegaly: Splenomegaly is listed as an alternate name or description for symptom Swollen spleen.
		Massive splenomegaly is characteristic of Gaucher's disease, chronic myeloid leukemia, kala azar, and agnogenic...
		Splenomegaly, or enlargement of the spleen, occurs when the spleen exceeds 12 cm in length, 7 cm in width, or 150 g...
	www.wrongdiagnosis.com /symptom/splenomegaly.htm (633 words)

	Ferret Splenomegaly FAQ (Site not responding. Last check: )
		Splenomegaly, or the enlargement of the spleen, is one of the biggest question marks in ferret medicine today.
		I believe that chronic infection in ferrets due to gastric Helicobacter infection is responsible for a large number (not all) cases of splenomegaly in the ferret.
		Splenomegaly is a very common finding in the ferret, especially in those over 3 years of age.
	www.rud.dk /ferrets/faqhtml/med/spleen.html (1673 words)

	eMedicine - Splenomegaly : Article by Lewis J Kaplan, MD, FACS
		Inflammatory splenomegaly: This is acute enlargement of the spleen that develops in association with various infections or inflammatory processes and results from an increase in the defense activities of the organ.
		Hyperplastic splenomegaly: In this setting, splenomegaly is thought to reflect work hypertrophy resulting from the removal of abnormal blood cells from the circulation (either cells with intrinsic defects or cells coated with antibody) or, in some cases, as the result of extramedullary hematopoiesis (ie, myeloproliferative disease).
		Leukopenia: Increased destruction or sequestration of leukocytes causes the leukopenia observed in splenomegaly.
	www.emedicine.com /med/topic2156.htm (4184 words)

	MedlinePlus Medical Encyclopedia: Splenomegaly
		Splenomegaly is an enlargement of the spleen beyond its normal size.
		Appropriate limitation of activity, including avoiding contact sports, will help prevent trauma that might cause the spleen to rupture.
		Care will be required for the specific condition causing the splenomegaly.
	www.nlm.nih.gov /medlineplus/ency/article/003276.htm (409 words)

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