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Topic: Statistical parametric mapping

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	Statistical parametric mapping - Wikipedia, the free encyclopedia
		Statistical parametric mapping or SPM is a statistical technique for examining differences in brain activity recorded during functional neuroimaging experiments using neuroimaging technologies such as fMRI or PET.
		Parametric statistical models are assumed at each voxel, using the general linear model to describe the variability in the data in terms of experimental and confounding effects, and residual variability.
		SPM is software written by the Wellcome Department of Imaging Neuroscience at University College London to aid in the analysis of functional neuroimaging data.
	en.wikipedia.org /wiki/Statistical_parametric_mapping (1002 words)

	[No title] (Site not responding. Last check: 2007-11-03)
		We have adapted a system developed for analysis of noninvasive imaging studies in humans, statistical parametric mapping (SPM), which was developed to reduce the subjectivity of cerebral activation studies.We studied freely-moving non-tethered rats that received bolus injections of radio-labeled iodo[14C]antipyrine, a tracer for cerebral blood flow.
		A parametric statistical model (GLM) was assumed at each voxel to characterize the variability in the data in terms of motor-induced cerebral-activation effects.
		Statistical Parametric Mapping (SPM) is widely used in the analysis and statistical mapping of human brains, derived from fMRI, PET, and SPECT data.
	www.ps.uci.edu /~markm/autorad/poster.doc (990 words)

	[No title] (Site not responding. Last check: 2007-11-03)
		Statistical Parametric Mapping (SPM) has been used for the statistical analysis of EEG topographic maps (1, 2), and later extensively for PET and fMRI (3), but not, to our knowledge, to the bioelectromagnetic source estimation problem.
		SPM-derived source maps are expected to be useful in suppressing the effects of stationary noise processes, comparing the effects of changes in experimental parameters, and also to facilitate the comparison between different source maps.
		Source maps were obtained for the peak of the auditory N100 evoked response (250 presentations of a tone burst (90% standard tones, 10% intensity oddballs) to the right ear), and displayed as axial slice sequences (nose up, left on left).
	www.neurologie.uni-duesseldorf.de /HBM99/cd/methods/1844.html (499 words)

	Journal of Cerebral Blood Flow & Metabolism - 11C-Diprenorphine Binding in Huntington's Disease: A Comparison of ...
		This study suggests that SPM is a valid alternative to conventional ROI analytical approaches for determining binding changes with positron emission tomography and may have advantages over region-based analyses in exploratory studies.
		Statistical parametric mapping (SPM) has been widely used to localize regions of activation in cerebral blood flow studies when tasks are performed by individuals and groups.
		parametric images correlate strongly with the regional total volumes of distribution, are relatively insensitive to regional differences in flow and delivery of diprenorphine, and are well defined by the measured data.
	www.nature.com /jcbfm/journal/v17/n9/full/9590277a.html (4882 words)

	[No title] (Site not responding. Last check: 2007-11-03)
		Statistical parametric mapping, or SPM, refers to the construction and assessment of spatially extended statistical processes used to test hypotheses about neuroimaging data.
		SPM is a voxel based morphometric analysis method that allows localization of structural differences between patient populations on a voxel-by-voxel basis.
		Illustrated here is an SPM of the extensive structural maturational changes that occur in the human brain between childhood and young adulthood.
	www.loni.ucla.edu /SVG/Animations/Development_1.html (91 words)

	Analyze - Wikipedia, the free encyclopedia
		It is a commercial program and is used for medical tomographic scans from magnetic resonance imaging, computed tomography and positron emission tomography.
		Its file format has been widely used in the functional neuroimaging field, and other programs such as SPM, AIR and MRIcro are able to read and write the format.
		SPM has defined changes to this format, among other things the voxel ordering within the file.
	en.wikipedia.org /wiki/Analyze (184 words)

	SPM - Statistical Parametric Mapping (Site not responding. Last check: 2007-11-03)
		Statistical Parametric Mapping refers to the construction and assessment of spatially extended statistical processes used to test hypotheses about functional imaging data.
		Parametric statistical models are assumed at each voxel, using the General Linear Model GLM to describe the data in terms of experimental and confounding effects, and residual variability.
		Classical statistical inference is used to test hypotheses that are expressed in terms of GLM parameters.
	www.fil.ion.ucl.ac.uk /spm (558 words)

	Journal of Cerebral Blood Flow & Metabolism - Changes of Cerebral Blood Flow During Short-Term Exposure to ...
		Quantitative parametric maps representing cerebral blood flow were then calculated using the integration method described by Alpert et al.
		Transformation and statistical parametric mapping were performed using the software SPM95 (Friston et al., 1995, 1996).
		The result of statistical parametric mapping to screen for regions with above-average flow increases is shown in Fig.
	www.nature.com /jcbfm/journal/v18/n8/full/9590434a.html (2954 words)

	Barnes, Ph.D., Anna (Site not responding. Last check: 2007-11-03)
		Statistical Parametric Mapping (SPM99 —Wellcome Department of Cognitive Neurology, London) is one of the statistical methods used by this laboratory in these investigations.
		The statistics module contains a suite of statistical tests—based on t-tests and correlation analysis—that can be used to investigate a single patient and a group or groups of patients while performing carefully specified tasks to tease out motor functions that highlight particular aspects of a disease.
		In addition, we are also applying multivariate voxel-by-voxel statistical methods to PET neuroactivation experiments to investigate the networks in the brain that are involved in controlling movement.
	www.northshorelij.com /body_nonav.cfm?id=2624 (438 words)

	DNL - MatLab Training Session 4
		The SPM software is a suite of MatLab functions and subroutines (with some externally compiled C routines) for functional PET and MRI brain image analysis that implements "statistical parametric mapping".
		SPM was developed by members and collaborators of the Functional Imaging Laboratory (FIL), Institute of Neurology, London and is distributed as open source code (http://www.fil.ion.ucl.ac.uk/spm).
		SPM generates many variables during analysis, but only a limited set quantities can plotted using the SPM graphical interface.
	dnl.ucsf.edu /matlab/session4.html (1863 words)

	NetSolve: Statistical Parametric Mapping (SPM)
		The Statistical Parametric Mapping (SPM) package was developed by members and collaborators of the Wellcome Department of Cognitive Neurology.
		Statistical Parametric Mapping refers to the construction and assessment of spatially extended statistical process used to test hypotheses about [neuro]imaging data from SPECT/PET and fMRI.
		Although parts of the SPM code are inherently parallel, very little work has been done previously to take advantage of this program structure.
	icl.cs.utk.edu /netsolvedev/applications/spm.html (238 words)

	[No title]
		The goal of this work is to test the accuracy and sensitivity of statistical parametric mapping (SPM) for detecting small or medium size brain activations from PET images, and to quantify the effect of two different spatial normalization methods in the detection of the activation foci.
		When no multiple comparison correction was applied to the t-maps derived for a p=0.001 level threshold, and using a p=0.5 level extent threshold, all true activations were detected for both spatial normalization methods, and for both activation levels, although the hippocampus activation was not detected as a site separate from the right temporal lobe.
		This implies that the SPM voxel-wise correction of the p-values might be overly conservative.
	www.neurologie.uni-duesseldorf.de /HBM99/cd/methods/2226.html (715 words)

	SPM - Documentation (Site not responding. Last check: 2007-11-03)
		SPM is an academic software toolkit for the analysis of functional imaging data, for users familiar with the underlying statistical, mathematical and image processing concepts.
		This can be launched from the SPM splash screen "About SPM", from the SPM menu window, or with the various context-sensitive help buttons.
		The SPM suite and associated theory was originally developed by Karl Friston for the routine statistical analysis of functional neuroimaging data from Positron Emission Tomography (PET), while at the Medical Research Council Cyclotron Unit.
	www.fil.ion.ucl.ac.uk /spm/dox.html (602 words)

	PET community mailing lists
		Statistical Parametric Mapping SPM is the generic name for the image processing and statistical techniques developed by members and collaborators of the Wellcome Department of Cognitive Neurology for the voxel-by-voxel analysis of functional [neuro]imaging data.
		The SPM discussion list is a UK-based worldwide email broadcast system for discussion and help with the methodology, implementation and use of Statistical Parametric Mapping in the SPM package.
		The SPM homepage is at URL: http://www.fil.ion.ucl.ac.uk/spm from where the software, examplar data, papers and documentation can be obtained.
	www.nucmed.buffalo.edu /prevweb/cpetmail.htm (1297 words)

	SPMd - Statistical Parametric Mapping Diagnosis
		SPM distribution page for SPM hardware and software requirements, downloading and installation instructions, and conditions of distribution.
		The essential difference between the two versions is that the submitted version has detailed appendicies on the derivation of the various diagnostic statistics used.
		General SPMd issues and idiosyncrasies should be raised on the SPM email discussion list, at , which the authors monitor.
	www.sph.umich.edu /~nichols/SPMd (902 words)

	Search Results: spm - ABCNEWS.com
		SPM is a MATLAB software package implementing Statistical Parametric Mapping for neuroimaging data.
		The SPM software is a suite of Matlab functions and subroutines with some externally compiled C routines.
		SPM will be followed by the Shape Modeling International (SMI) conference, which will start on Wednesday June 15 with...
	infospace.abcnews.com /_1_ZU5T7O03GG6FHY__info.abcnws/dog/results?otmpl=dog/webresults.htm&qcat=web&ran=&qkw=spm (750 words)

	SPM - Wikibooks, collection of open-content textbooks
		SPM (statistical parametric mapping) examines differences in brain activity recorded during functional neuroimaging experiments.
		SPM uses brain imaging technologies such as fMRI or PET.
		This wiki describes how to use freely-available SPM libraries written in MatLab and C. This website is a wiki which means that you can edit it and add content.
	en.wikibooks.org /wiki/SPM (395 words)

	Statistical parametric mapping with 18F-dopa PET shows bilaterally reduced striatal and nigral dopaminergic function in ... (Site not responding. Last check: 2007-11-03)
		Statistical parametric mapping with 18F-dopa PET shows bilaterally reduced striatal and nigral dopaminergic function in early Parkinson's disease -- Ito et al.
		Statistical parametric mapping is an approach developed to localise statistically significant changes in spatially normalised
		SPMs and peak coordinates are shown in fig 3 and table 2, respectively.
	jnnp.bmjjournals.com /cgi/content/full/66/6/754 (2889 words)

	Grey matter abnormalities in obsessive--compulsive disorder: Statistical parametric mapping of segmented magnetic ...
		Grey matter abnormalities in obsessive--compulsive disorder: Statistical parametric mapping of segmented magnetic resonance images -- KIM et al.
		Friston, K. J., Holmes, A. P., Worsley, K. et al (1995) Statistical parametric maps in functional imaging: a general linear approach.
		Sowell, E. R., Levitt, J., Thompson, P. et al (2000) Brain abnormalities in early-onset schizophrenia spectrum disorder observed with statistical parametric mapping of structural magnetic resonance images.
	bjp.rcpsych.org /cgi/content/full/179/4/330 (3058 words)

	[No title] (Site not responding. Last check: 2007-11-03)
		function varargout=spm(varargin) % SPM: Statistical Parametric Mapping (startup function) %_______________________________________________________________________ % ___ ____ __ __ % / __)(_ \(\/) % \__ \)___/) (Statistical Parametric Mapping % (___/(__) (_/\/\_) SPM - !http://www.fil.ion.ucl.ac.uk/spm %_______________________________________________________________________ % % SPM (Statistical Parametric Mapping) is a package for the analysis % functional brain mapping experiments.
		The interface consists of three % windows: A menu window with pushbuttons for the SPM routines (each % button has a 'CallBack' string which launches the appropriate % function/script); A blank panel used for interaction with the user; % And a graphics figure with various editing and print facilities (see % spm_figure.m).
		For SPM to pick a toolbox up, % there must be a single mfile in the directory whose name ends with % the toolbox directory name.
	www.umich.edu /~fmri/course/files/spm2/spm.m (1726 words)

	WOBIB: 89 - Okazawa, et al. (2000) Statistical mapping ... (Site not responding. Last check: 2007-11-03)
		Statistical mapping analysis of serotonin synthesis images generated in healthy volunteers using positron-emission tomography and alpha-[11C]methyl-L-tryptophan.
		OBJECTIVES: To assess the suitability of analyzing functional images of brain serotonin (5-HT) synthesis with statistical parametric mapping (SPM), and to investigate further possible sex-related regional differences.
		CONCLUSION: SPM analyses of PET alpha-[11C]MTrp data may be of value for identifying regional differences in brain 5-HT synthesis between groups, and in investigating the effects of psychotropic drugs.
	hendrix.imm.dtu.dk /services/jerne/brede/WOBIB_89.html (907 words)

	Brain Perfusion SPECT: Age- and Sex-related Effects Correlated with Voxel-based Morphometric Findings in Healthy Adults ... (Site not responding. Last check: 2007-11-03)
		The images show parametric maps on which the voxels with a significant negative correlation with age are superimposed on a template for the 15 youngest volunteers in the study.
		The maps show that the decrease in gray matter concentration with age is greater than the perfusion changes.
		Parametric mapping of cerebral blood flow deficits in Alzheimer’s disease: a SPECT study using HMPAO and image standardization technique.
	radiology.rsnajnls.org /cgi/content/full/221/3/810 (4884 words)

	Neuropsychiatric Imaging Research Laboratory - Duke University Medical Center
		K. Van Leemput that provides fully automated segmentation of brain tissues in MR Images using a geometric model and unifying statistical classification based approach.
		The SPM programs are a suite of MatLab functions developed by The Wellcome Trust for interpretation of neuroimaging data.
		SPM uses a voxel based approach to spatially normalize and smooth neuroimages into a standard space.
	nirlweb.mc.duke.edu /programs.htm (563 words)

	Whole-brain T2 mapping demonstrates occult abnormalities in focal epilepsy -- Rugg-Gunn et al. 64 (2): 318 -- Neurology
		Whole-brain T2 mapping demonstrates occult abnormalities in focal epilepsy -- Rugg-Gunn et al.
		Rugg-Gunn, Boulby, Symms, and Duncan), National Society for Epilepsy and Department of Clinical and Experimental Epilepsy, and Department of Neuroinflammation (Dr. Barker), Institute of Neurology, University College London, and Centre for Neuroimaging Sciences (Dr. Barker), Institute of Psychiatry, London, UK.
		mapping was sensitive in patients with malformations of cortical
	www.neurology.org /cgi/content/abstract/64/2/318 (347 words)

	Differential Lesion Patterns in CADASIL and Sporadic Subcortical Arteriosclerotic Encephalopathy: MR Imaging Study with ... (Site not responding. Last check: 2007-11-03)
		Statistical parametric mapping group comparisons between FLAIR images (4-mm FWHM Gaussian kernel) in 27 patients with CADASIL and 20 with sSAE without (A, C) and with (B, D) corrected cluster thresholding.
		Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy maps to chromosome 19q12.
		Statistical parametric maps in functional imaging: a general linear approach.
	radiology.rsnajnls.org /cgi/content/full/218/2/443 (4665 words)

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