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Topic: Steroid hormones


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  Steroid - Wikipedia, the free encyclopedia
Steroid hormones produce their physiological effects by binding to steroid hormone receptor proteins.
All steroid hormones are synthesized from pregnenolone, a derivative of cholesterol.
Steroids and retinoids are both hydrophobic, pass through cell membranes and bind to intracellular receptors.
en.wikipedia.org /wiki/Steroid   (335 words)

  
 Anabolic steroid - Wikipedia, the free encyclopedia
Anabolic steroids are a class of natural and synthetic steroid hormones that promote cell growth and division, resulting in growth of muscle tissue and sometimes bone size and strength.
In addition, steroid use to enhance athletic performance is no longer limited to high school males: a 1998 Pennsylvania State University study found that 175,000 high school girls nationwide reported taking steroids at least once in their lifetime.
Anabolic steroids are believed to have been inadvertently discovered by German scientists in the early 1930s, but at the time the discovery was not considered significant enough to warrant further study.
en.wikipedia.org /wiki/Anabolic_steroid   (1196 words)

  
 [No title]
Steroid hormones are all characterized by the steroid nucleus which is composed of three six member rings and one five member ring, ingeniously labeled A, B, C, and D respectively.
Steroid- is a fat soluble organic compound with an origin from plants or animals; it is characterized by its "steroid nucleus" and is a class of lipid.
Steroid hormones are crucial for many enzymatic reactions, the glucocorticoids trigger a variety of cellular responses including the synthesis of second messengers such as cAMP in the short term and the modulation of protein synthesis in the long term.
www.cs.stedwards.edu /chem/Chemistry/CHEM43/CHEM43/Steroids/Steroids.HTML   (2129 words)

  
 Steroid Hormones
With the exception of retinoic acid, the steroid hormones are all derived from cholesterol.
Unlike peptide hormone receptors, that span the plasma membrane and bind ligand outside the cell, steroid hormone receptors are found in the cytosol and the nucleus.
The steroid hormone receptors belong to the steroid and thyroid hormone receptor super-family of proteins, that includes receptors for steroid hormones, thyroid hormones, vitamin D and vitamin A (retinoic acid).
web.indstate.edu /thcme/mwking/steroid-hormones.html   (2439 words)

  
 BBC - h2g2 - Steroid Hormones
For that reason every hormone is synthesised by specialised cells commonly found in various glands (eg, the pineal gland in the brain, the testicles or ovaries, etc.), from where the hormones are injected into the body fluids (eg, lymph, blood, etc.).
One special family of hormones are the steroid hormones (except for retinoic acid), for which the basic precursor is cholesterol, a molecule infamous for causing cardio-vascular problems.
That is, most steroid hormones cannot be found swirling around the blood in their free form (although some actually are - 10% of cortisol is free in the blood, for example).
www.bbc.co.uk /dna/h2g2/A684362   (1093 words)

  
 Steroid hormone metabolism
The steroid hormones are synthesized mainly by endocrine glands such as the gonads (testis and ovary), the adrenals and (during gestation) by the fetoplacental unit, and are then released into the blood circulation.
Thus, gonadal steroids influence the sexual differentiation of the genitalia and of the brain, determine secondary sexual characteristics during development and sexual maturation, contribute to the maintenance of their functional state in adulthood and control or modulate sexual behaviour.
Steroid receptor genes are only expressed in target tissues, where their presence determines accumulation of the hormone in the cell nucleus and facilitates steroid entry into the target cell by the law of mass action.
www.gfmer.ch /Books/Reproductive_health/Steroid_hormone_metabolism.html   (3495 words)

  
 Steroid hormones   (Site not responding. Last check: 2007-10-21)
In steroid hormones, the rings are fused in a trans orientation to form an overall planar structure.
Pregnenolone is an intermediate in the synthesis of all steroid hormones.
Hypothalmic CRH (corticotropin-releasing hormone) causes release of ACTH (adrenal cortical tropic hormone) from the anterior pituitary.
www.neurosci.pharm.utoledo.edu /MBC3320/steroid_hormones.htm   (884 words)

  
 e-Hormone.com: Hormones, endocrine system, glands, actions   (Site not responding. Last check: 2007-10-21)
Hormones are chemical signaling molecules (peptides, proteins or steroids) produced in one site of the body that then travel to another site to have an effect.
Hormones may be made and have an action locally or may be made in one endocrine gland and have an effect at a distant site.
The ovaries produce the steroid hormones (estrogens and progesterone) that cause the development of secondary sexual characteristics and develop and maintain the reproductive function in the female.
www.e-hormone.com   (2871 words)

  
 Steroid hormones and receptors   (Site not responding. Last check: 2007-10-21)
Steroid receptors are proteins found in the cytoplasm or nucleus of eukaryotic cells which bind to and regulate the transcription of DNA under the regulation of steroid hormones.
This sequence permits the receptor with bound hormone (ligand) to translocate from the cytosol to the nucleus.
Steroid hormone receptors have been shown to increase the level of activity of tyrosine transaminase, alanine transaminase, and glycogen synthetase in liver cells by as much as 150%.
www.neurosci.pharm.utoledo.edu /MBC3320/steroids.htm   (2230 words)

  
 Steroid Information & Steroid Alternatives   (Site not responding. Last check: 2007-10-21)
Anabolic steroids were developed in the late 1930s primarily to treat hypogonadism, a condition in which the testes do not produce sufficient testosterone for normal growth, development, and sexual functioning.
During the 1930s, scientists discovered that anabolic steroids could facilitate the growth of skeletal muscle in laboratory animals, which led to use of the compounds first by bodybuilders and weightlifters and then by athletes in other sports.
Steroidal supplements can be converted into testosterone (an important male sex hormone) or a similar compound in the body.
www.steroidinformation.com   (624 words)

  
 Steroid Hormones Results   (Site not responding. Last check: 2007-10-21)
A steroid is a type of lipid, characterized by a carbon skeleton with four fused rings.
steroids are cholesterol, the steroid hormones, and their precursors and...
Steroid hormones are all characterized by the steroid nucleus which is...
www.ttestosterone-net.com /directory/steroid-hormones.html   (467 words)

  
 Human Endocrinology
These hydrophilic (and mostly large) hormone molecules bind to receptors on the surface of "target" cells; that is, cells able to respond to the presence of the hormone.
Hormone secretion is increased (or decreased) by the same substance whose level is decreased (or increased) by the hormone.
Although a few hormones circulate simply dissolved in the blood, most are carried in the blood bound to plasma proteins.
users.rcn.com /jkimball.ma.ultranet/BiologyPages/H/Hormones.html   (640 words)

  
 Steroid hormones   (Site not responding. Last check: 2007-10-21)
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steroid.com.ru /steroid-hormones.html   (1015 words)

  
 steroid --  Britannica Student Encyclopedia
Steroids are a class of naturally occurring organic substances and their derivatives that are of great importance in biology, medicine, and chemistry.
In vertebrates, cholesterol is the central precursor of all steroid hormones secreted by the testes of the male, the ovaries of the female, and the adrenals of both sexes.
steroid hormone secreted by adrenal gland; principal regulator of salt and water balance in human body; plays small role in metabolism of fats, carbohydrates, and proteins; synthesized from corticosterone, a steroid derived from cholesterol; adults produce about 20 to 200 micrograms of aldosterone per day; production of aldosterone regulated by secretion from kidney in...
www.britannica.com /ebi/article-9277231   (858 words)

  
 Peptide Hormones
Steroid and thyroid hormones are hydrophobic and diffuse from their binding proteins in the plasma, across the plasma membrane to intracellularly localized receptors.
The principal hormones of the posterior pituitary are the nonapeptides
The primary function of the pancreatic hormones is the regulation of whole-body energy metabolism, principally by regulating the concentration and activity of numerous enzymes involved in catabolism and anabolism of the major cell energy supplies.
www.indstate.edu /thcme/mwking/peptide-hormones.html   (6153 words)

  
 Free Diffusion of Steroid Hormones Across Biomembranes: A Simplex Search with Implicit Solvent Model Calculations -- ...
The diffusion coefficient of a steroid hormone in an aqueous
Kawata, M. Roles of steroid hormones and their receptors in structural organization in the nervous system.
Penetration of endogenous steroid hormones corticosterone, cortisol, aldosterone and progesterone into the brain is enhanced in mice deficient for both mdr1a and mdr1b P-glycoproteins.
www.biophysj.org /cgi/content/full/87/2/768   (6344 words)

  
 Multiple Actions of Steroid Hormones---A Focus on Rapid, Nongenomic Effects -- Falkenstein et al. 52 (4): 513 -- ...
Steroid receptors are structurally organized in different domains, which have been confirmed by results of cDNA cloning experiments: 1) a variable N-terminal region, which may have modulatory effects on transactivation (regions A/B, with a variable length of 50-500 amino acids).
cognate steroid hormone receptor in the cytosol, the heat-shock
hormones, dissociate from the receptors (Pratt and Toft, 1997
pharmrev.aspetjournals.org /cgi/content/full/52/4/513   (7371 words)

  
 anabolic steroid hormones
Steroid How Hormones Work - Anabolic steroid hormones are synthetic substances that are related steroid the - Anabolic production hormones stimulate the to of protein which is -
Anabolic Steroid Steroids - Anabolic steroids artificially raise the and of anabolic hormones in the blood amount permit further growth.
There is no better guide to steroid use for the beginner to intermediate user out there, and Mick's "No Bull" writing style means that you will be highly entertained as you get educated about safe and effective steroid use.
www.safesteroiduse.com /anabolic-steroid-hormones.htm   (685 words)

  
 STEROID HORMONES
To date, however, no evidence has been uncovered to show that 19-nortestosterone is produced endogenously, despite the fact that tens of thousands of urine samples have been analyzed since 1980 using capillary column chromatography coupled with mass spectrometry.
There is still the possibility, however, that increasing the sensitivity of a test for a synthetic steroid like 19-nortestosterone, will increase the possibility of detecting trace amounts of the same steroid produced naturally by minor pathways.
Thus the athlete might escape detection of the anabolic steroids he was using (if he stopped them early enough) but may be found positive for 19- nortestosterone - even though he may never have used the 19-nortestosterone.
www.geocities.com /whitess33/steroid-hormones.html   (365 words)

  
 Merck Vet. Edition - Steroid Hormones
The naturally produced endogenous steroids are not orally active, require relatively large doses to be administered for physiologic effects, and can transiently affect the behavior of treated animals (see Table: Natural Steroid Hormones for Consideration as Growth Promoters).
When administered in compressed tablets, a second steroid (usually testosterone or progesterone) should be present, in a ratio of ~1 part estradiol to 10 parts of the other steroid, to slow down the release rate of estradiol and prolong the effective life span of the implant to ~100 days.
In addition to natural steroids, synthetic steroids are also used because they are generally more potent, have less androgenicity, and thus have less adverse effects on behavior (see Table: Synthetic Steroid Hormones for Consideration as Growth Promoters).
www.merckvetmanual.com /mvm/htm/bc/191902.htm   (729 words)

  
 Hormones
Steroid hormones are secreted by the gonads, adrenal cortex, and placenta.
Steroid hormones are derived from cholesterol by a biochemical reaction series.
Once synthesized, steroid hormones pass into the bloodstream; they are not stored by cells, and the rate of synthesis controls them.
www.cartage.org.lb /en/themes/Sciences/LifeScience/GeneralBiology/Physiology/EndocrineSystem/Hormones/Hormones.htm   (330 words)

  
 Steroid hormones (from pharmaceutical industry) --  Encyclopædia Britannica   (Site not responding. Last check: 2007-10-21)
any of a group of hormones that belong to the class of chemical compounds known as steroids; they are secreted by three “steroid glands”—the adrenal cortex, testes, and ovaries—and during pregnancy by the placenta.
In the parent structure (named gonane and referred to as the steroid nucleus), the carbon atoms are bonded to 28 hydrogen atoms.
After being released by neurosecretory cells of the brain, the thoracotropic hormone is carried by the blood to the prothoracic glands, where it stimulates the release of ecdysone in insects or crustecdysone in crustaceans, steroid hormones that initiate molting (the periodic shedding of the outer skeleton).
www.britannica.com /eb/article-82326?tocId=82326   (825 words)

  
 Steroid. Anabolic steroid online   (Site not responding. Last check: 2007-10-21)
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 steroid encyclopedia   (Site not responding. Last check: 2007-10-21)
Steroid hormone -- Facts, Info, and Encyclopedia articleSteroid hormones are (Any of several fat-soluble organic compounds having as a...
Steroid -- Facts, Info, and Encyclopedia articleA steroid is a type of (An oily organic compound insoluble in water but soluble...
Steroid - definition of Steroid in EncyclopediaIn chemistry and biology, Steroids are a type of lipid, characterized by a carbon skeleton with four fused rings.
steroid.capode.com /steroid-encyclopedia   (341 words)

  
 Plant Physiology Online: Brassinosteroids: A New Class of Plant Steroid Hormones
Mammalian steroid 5α-reductases catalyze an NADPH-dependent conversion of testosterone to dihydrotesterone—a key step in steroid metabolism, which is essential for normal embryonic development of male external genitalia and prostate.
BR levels are regulated by hormone signaling through the feedback inhibition of the biosynthetic genes as well as by BR inactivating enzymes such as the steroid hydroxylase (BAS1) and sulfotransferases.
Recognition of BRs as authentic plant hormones was delayed because the developmental effects of BRs qualitatively resemble those of auxins and exogenously applied BRs result in phenotypes that show complex interactions with the better-known phytohormones: gibberellic acid, abscisic acid, ethylene, and cytokinin.
www.plantphys.net /article.php?ch=e&id=201   (1995 words)

  
 Non-Genomic Actions of Anabolic Steroid Hormones
I consider myself well versed on steroids and how they work, but one thing that continually has me puzzled is this; if there is only one androgen receptor that all steroids bind to in order to induce growth, how come there are so many diverse effects of different synthetic steroids.
All in all, steroids affect cells through several different pathways and at least one atypical steroid receptor, none of which involve what most people consider the true "intracellular" mechanism of steroid action.
It is time for bodybuilders and steroid gurus alike to update their knowledge of the mechanism of action of the drugs the use and direct the use of.
www.mesomorphosis.com /articles/haycock/non-genomic-actions-of-anabolic-steroids.htm   (1499 words)

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