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Exercise14 Skin   (Site not responding. Last check: 2007-09-17) The deepest layer of the epidermis is the stratum basale. The stratum spinosum (SS) and stratum basale (SB) are labeled (note the melanin in the latter!) and the stratum granulosum (not labeled) is visible in the left-hand image. This is the stratum corneum or "horny layer." It's the actual interface between the outer surface of the animal and its environment, the layer from whence cells are cast off in the normal process of wear and tear. education.vetmed.vt.edu /Curriculum/VM8054/Labs/Lab14/Lab14.htm   (4593 words)

Proceedings of the Oklahoma Academy of Science Nearest the outer surface is a layer of cornified dead cells (stratum corneum); next is the granular cell layer (stratum granulosum); next the pentagonal cell layer (the stratum spinosum); and finally the undifferentiated cells stratum germinativum. The lower density of gap junctions in the stratum granulosum raised the possibility that the cells in that layer did not exchange ions with the neighboring strata. The zero-time gap junction density of the stratum granulosum found in this study (0.041 ± 0.013) is not significantly different from the gap junction density (0.04 ± 0.018) found previously (6). digital.library.okstate.edu /oas/oas_htm_files/v73/p23_27nf.html   (2273 words)

Functional organization of the bovine rumen epithelium -- Graham and Simmons 288 (1): R173 -- AJP - Regulatory, ... -subunit at the stratum basale at the basal lamina with decreasing intensity across the stratum spinosum to the stratum granulosum and stratum corneum. spinosum, and the stratum basale of the bovine rumen epithelium. diffusional influx at the stratum granulosum to be transmitted ajpregu.physiology.org /cgi/content/full/288/1/R173   (5008 words)

MerckMedicus : Dorland's Medical Dictionary   (Site not responding. Last check: 2007-09-17) granulo´sum epider´midis granular layer of epidermis: the layer of the epidermis between the stratum lucidum epidermidis and the stratum spinosum epidermidis. lacuno´sum the fibrous layer situated between the stratum radiatum and the stratum moleculare of the hippocampus, consisting chiefly of a dense fiber layer in association with Schaffer collaterals, axons ascending from the alveus, and axons and collaterals ascending from neurons of the stratum oriens. spino´sum epider´midis spinous layer of epidermis: the layer of the skin between the stratum granulosum epidermidis and the stratum basale epidermidis characterized by the presence of prickle cells. merckmedicus.com /pp/us/hcp/thcp_dorlands_content.jsp?pg=/ppdocs/us/common/dorlands/dorland/dmd_s_25.htm   (4142 words)

Exam - USPharmacist Stratum lucidum, stratum spinosum, stratum corneum, stratum germinativum, basal membrane Stratum corneum, stratum malphigii, stratum germinativum, stratum spinosum, basal membrane Stratum corneum, stratum spinosum, stratum granulosum, basal membrane www.uspharmacist.com /ce/CETest.asp?exam_type=view_only&lsn_id=2716   (733 words)

Dr. Ben Bramwell The epidermis may further be divided into the following four or five layers (from the top down): the stratum corneum, the stratum lucidum (in the lips and thickened skin of the soles and palms), the stratum granulosum, the stratum spinosum, and the stratum basale. Stratum spinosum is made of several layers of cells that stain with spine-like extensions; these cells have limited mitotic activity. Stratum basale is a single layer of cuboidal cells in contact with the basement membrane. departments.weber.edu /Zoology/Lecture6.htm   (811 words)

Ovary 1b   (Site not responding. Last check: 2007-09-17) The cells of the stratum granulosum that surround the developing ovum form a layer called the corona radiata. Outside the stratum granulosum is a two-layered structure called the theca. The theca interna (next to the stratum granulosum) contains large, glandular cells and is responsible for secreting androgens that will be converted into estrogens by the granulosa cells. bioweb.uwlax.edu /APlab/Table_of_Contents/Lab_18/Ovary_1/Ovary_1b/ovary_1b.html   (168 words)

Blue Histology - Integumentary System Keratinisation should not be used as a synonym for the formation of the stratum corneum: other stratified squamous epithelia may become keratinised but may not form a stratum corneum in which cells join to form a horny cell membrane. The stratum granulosum is formed by a single layer of very dark and flattened cells in thin skin. The stratum basale is formed by a single layer of cuboidal or columnar cells and delimits the epidermis from the dermis. www.lab.anhb.uwa.edu.au /mb140/CorePages/Integumentary/Integum.htm   (3331 words)

Integument   (Site not responding. Last check: 2007-09-17) The pointer on the upper left side of the image indicates the third layers known as the stratum granulosum. The stratum granulosum is a relatively thin layer with cells that appear elongated, flattened, and squamous. The fourth pointer in the upper central portion of the image indicates the layer termed the stratum lucidum. www.usc.edu /hsc/dental/ghisto/skn/c_5.html   (122 words)

Eucerin®: Skin and Cells The stratum spinosum (spino = thorn, prickle/lat.), the prickle-cell layer, is above the basal layer. Above the prickle-cell layer is the stratum granulosum (granula = grain/Lat.), where the cornification (keratinization) of the keratinocytes begins. The stratum corneum (cornea = horny skin/Lat.) is the uppermost layer of the epidermis. www.eucerin.co.uk /skin/skincell_2.html   (486 words)

Visual Changes Skin Care The stratum corneum consists of tightly packed, scale­like cells which are continually being shed (exfoliated) and replaced. The stratum spinosum is often classified witht the stratum germinativum to form the basal layer. The stratum germinativum (basal layer) is responisble for the growth of the epidermis and is where your skin produces melanin. www.visualchanges.com /skinscience.html   (554 words)

Histology BIOL 4000 - Integument - Lecture Notes 11 This is supported by the fact that the stratum spinosum is thicker in portions of skin subject to frequent abrasion such as palms and soles. Since the upper layer of skin is heavily keratinized and the lower layer (stratum germinativum) is not, it is clear that as cells of the epidermis progress toward the external surface, one of the things that is happening is that higher and higher concentrations of keratin are being synthesized and deposited in the cytoplasm. The hair follicle, in a sense, is a deep invagination of the epidermis that involves the stratum basale and stratum spinosum. www.auburn.edu /academic/classes/zy/hist0509/html/Lec11Integument.html   (1543 words)

Thick Skin The connective tissue of the dermis consists of an upper relatively loose papillary layer and a lower reticular layer of dense irregular connective tissue. Note the dark staining characteristic of the Stratum granulosum, indicated by the white arrows. In thick skin where the Stratum Corneum (green arrow) is very thick, a fifth layer is present, which is the stratum lucidum. www3.umdnj.edu /histsweb/lab11/lab11thickskin.html   (946 words)

THE INTEGUMENTARY SYSTEM The skin is the body's largest organ, and serves many functions: regulation of body temperature, protection from environment, excretion of some wastes and absorption of some chemicals and vitamins, and sensation. This is the outermost layer of the epidermis. In thicker skin, the Stratum Lucidum will be found in between stratum corneum and stratum granulosum. www.crnasomeday.com /anatpages/integumentary.htm   (219 words)

SKIN The epidermis is composed of 5 sublayers and the dermis is composed of 2 sublayers, the papillary layer and the reticular layer. Notice that the slide to the right lacks a stratum lucidum. Remember, that sublayer is found only in the palms of the hand and soles of the feet and is seen in the slide to the far right. www.nku.edu /~dempseyd/SKIN.htm   (118 words)

Epithelium: Page 7   (Site not responding. Last check: 2007-09-17) The larger arrow is pointing to a discrete region or stratum, stratum spinosum within this tissue and away from the apical or free-surface side. The large arrow is pointing to the cells that make up the stratum granulosum, including those cells next to the stratum spinosum that are beginning to form discrete granules of keratin. During this fleeting process of autodegradation, the cells' internal structures fade, staining a light blue and form the stratum lucidum (small arrow), which is one cell layer or so thick in a very thick epidermis (slide 42a) or indistinguishable in the average-sized epidermis of most spp. sacs.vetmed.ufl.edu /histo/epi07.htm   (406 words)

INTEGUMENTARY SYSTEM stratum spinosum is composed of several layers of polyhedral cells, which flatten as the stratum granulosum is approached. stratum basalis is composed of a single layer of cuboidal to columnar cells, which are attached to the basement membrane by hemidesmosomes. reaction demonstrates that the cell bodies of most melanocytes are located in the stratum basale while their cytoplasmic processes (some times called dendritic processes) extend between cells of the stratum spinosum. www.mc.vanderbilt.edu /histology/labmanual2002/labsection2/Integumentarysystem03.htm   (3290 words)

A BOY WITH SPIKY SKIN   (Site not responding. Last check: 2007-09-17) Orthokeratosis and papillomatosis with marked vacuolization of the keratinocytes in the suprabasal layers are observed. In the stratum granulosum, an increased number and size of the keratohyalin granules is often observed. Genetic linkage studies have demostrated that EHK is caused by mutations in the genes encoding the suprabasilar keratins 1 and 10. www.med.wayne.edu /dermatology/webmichderm01/case10.htm   (521 words)

Environmental Control of the Survival and Differentiation of Dentate Granule Neurons -- Kim et al. 14 (12): 1358 -- ... stratum granulosum to form and extend the skeleton of that layer. stratum oriens was identified as the portion adjacent to the adjacent to the stratum pyramidale, with a width of cercor.oxfordjournals.org /cgi/content/full/14/12/1358   (4343 words)

INTEGUMENT As the keratinocytes move upward and differentiate, keratin filaments (a type of intermediate filament) aggregate to form larger groups of filaments (tonofilaments) and even larger tonofibrils which are visible by light microscopy in the spinosum layer. During differentiation, in the stratum granulosum, aggregations of keratin filaments become embedded in matrix proteins derived originally from keratohyaline granules. In the cells of the stratum corneum, this keratin protein complex occupies the entire dead cell. medocs.ucdavis.edu /CHA/402/labsyl/01/08.htm   (1665 words)

Laboratory 14: Integumentary System and Breast The stratum corneum is the uppermost layer and consists of desquamating enucleated cells. The stratum granulosum is comprised of keratinocytes that are intensely stained due to the presence of keratohyalin granules. The epidermis, dermis and hypodermis are histologically similar with the exception of the absence of a stratum lucidum and the presence of hair follicles which extend deep into the hypodermis. medinfo.ufl.edu /year1/histo/review/lab14.html   (1385 words)

Angiogenesis Foundation: Providers - Wound   (Site not responding. Last check: 2007-09-17) From the skin surface to the dermis, these are the: 1) stratum corneum; 2) stratum granulosum; 3) stratum spinosum; and 4) stratum basale (basal layer). The stratum spinosum is composed of keratinocytes that become larger, flatter, and contain less water as they travel to the surface of the skin. Finally, the stratum basale (basal layer) contains basal keratinocytes that grow and continually divide, eventually replacing terminally differentiated cells that migrate to the skin surface and are lost. www.angio.org /providers/woundcare/understandingWounds.html   (1312 words)

Histology-World! Histology Test Bank-Skin 3a The hypodermis is the loose connective tissue layer underneath the dermis. The epidermis is divided into five layers: stratum basale, stratum spinosum, stratum granulosum, stratum lucidum, and stratum corneum. The stratum spinosum consists of a layer several cells deep. www.histology-world.com /testbank/skin3a.htm   (699 words)

Study Outline   (Site not responding. Last check: 2007-09-17) 3. The stratum basale, a single layer of cuboidal to low columnar cells, rests on the basement membrane and consists of three types of cells. 5. The stratum granulosum consists of three to five layers of cells with granules of keratohyalin. 1. The growth of hair is due to mitosis in cells in the stratum basale of the epidermal root sheath. www.mhhe.com /biosci/ap/saladin2e/student/olc/chap07studoutline.mhtml   (1245 words)

INTEG Squamous cell carcinomas arise from the stratum corneum. the stratum corneum of the skin does not require nutrients because, this layer of cells is not living. ___________________ are found mostly in the stratum spinosum and play an important role in activating the immune response. www.utm.edu /staff/amills/integ.htm   (769 words)

ITTRCA Home Page The outer most layer of cells is known as the stratum corneum, the stratum lucidum directly under the stratum corneum, then the stratum granulosum, the stratum spinosum and the deepest layer of cells in the epithelium is the stratum germinativum, sometimes referred to as the basal layer. The replacement process is normally an orderly movement of cells from the stratum granulosum upward to the stratum corneum. On the way through progression of the four upper layers, the cells leave their nutrient supply behind, produce keratin, lose their nuclei and granules and die, forming scales in the outermost hard surface on the skin. www.afip.org /Departments/environmental/ittrca/path.html   (900 words)

Kelo-cote   (Site not responding. Last check: 2007-09-17) Starting with the deepest layer, known as the stratum basale, followed by the stratum spinosum, then the stratum granulosum, the stratum lucidum and finally the stratum corneum. The stratum basale anchors the upper layers of the skin to the underlying tissues while providing new cells to the outermose layer lost to abrasion. It is the stratum corneum that is actively involved in the process of exfoliation whereby the dead skin cells are shed and protect the underlying healthy tissue from damaged as a result of abrasion. homepages.tscnet.com /bsmith/article1.html   (396 words)

INTEGUMENTARY SYSTEM The epidermis differs from that of thick skin in having thinner stratum spinosum, granulosum, and corneum, and lacks the stratum lucidum (Thin Skin 1). The pigment of the skin is produced by melanocytes, which take up residence in the basal layer (stratum germinativum) and produce melanin or pigment granules (Melanocytes). The deepest portion of the hair follicle is composed only of stratum germinativum cells and is called the germinal matrix of the follicle. lifesci.rutgers.edu /~babiarz/integ.htm   (535 words)

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