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| | [No title] |
 | | We discuss the evidence for the existence of volume transmission of three important classical neurotransmitters of the striatum (dopamine, glutamate and GABA), the tentative mechanisms underlying this means of neuronal communication, receptors involved, and the role of volume transmission in the striatum in cotrolling behavioural functions. |
 | | The main function of the striatum is proposed to gather information from different cortical areas and then to convey integrated signals to the brain pre- motor area, on the one hand, and back to the cortex, on the other hand (Carlsson and Carlsson, 1990; Goldman-Rakis and Selemon, 1990; Shapovalova et al., 1992). |
 | | Irrespective of the role that cell clusters play in the striatum, it is likely that the diffusion of extracellular dopamine and acetylcholine within the cluster serves as an important mechanism of integration between cells in the cluster that influences functional state of the cluster as a whole. |
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