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Topic: Subunit


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In the News (Tue 2 Dec 08)

  
  Protein subunit - Wikipedia, the free encyclopedia
In structural biology, a protein subunit or subunit protein is a single protein molecule that assembles (or "coassembles") with other protein molecules to form a multimeric or oligomeric protein.
In some protein assemblies, one subunit may be referred to as a "regulatory subunit" and another as a "catalytic subunit." An enzyme composed of both regulatory and catalytic subunits when assembled is often referred to as a holoenzyme.
A subunit is often named with a greek or roman letter, and the numbers of this type of subunit in a protein is indicated by a subscript.
en.wikipedia.org /wiki/Protein_subunit   (222 words)

  
 Human protein: P30154 - Serine/threonine protein phosphatase 2A, 65 kDa regulatory subunit A, beta isoform (PP2A, ...
The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit.
pp2a consists of a common heterodimeric core enzyme, composed of a 36 kda catalytic subunit (subunit c) and a 65 kda constant regulatory subunit (pr65 or subunit a), that associates with a variety of regulatory subunits.
The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit.
harvester.embl.de /harvester/P301/P30154.htm   (1720 words)

  
 At3g09530 - exocyst subunit EXO70 family protein   (Site not responding. Last check: 2007-10-08)
At3g09530 is a homologue of At2g28640 (exocyst subunit EXO70 family protein) from Arabidopsis thaliana.
At3g09530 is a homologue of At2g28650 (exocyst subunit EXO70 family protein) from Arabidopsis thaliana.
At3g09530 is a homologue of At3g55150 (exocyst subunit EXO70 family protein) from Arabidopsis thaliana.
www.ihop-net.org /UniPub/iHOP/gg/5473.html   (240 words)

  
 The transmembrane domain of subunit b of the Escherichia coli F1FO ATP synthase is sufficient for H+-translocating ...   (Site not responding. Last check: 2007-10-08)
The transmembrane domain of subunit b of the Escherichia coli F1FO ATP synthase is sufficient for H+-translocating activity together with subunits a and c -- Greie et al.
and Arg36 and hydrophilic loops of subunit a[30,31].
subunit as an inhibitor of the proton-translocating ATPase of Escherichia coli.
content.febsjournal.org /cgi/content/full/271/14/3036   (3453 words)

  
 Archaeal Large Ribosomal Subunit Interactive Tour/UMASS Amherst
In the summer of 2000, the Steitz and Moore labs published a series of papers in the journal Science detailing the structure of the large subunit of the Archaeal Ribosome at 2.4 angstroms resolution (1,2,3).
The subunit was purified from a rather obscure organism, the archaea Haloarcula marismortui.
The accession number of the NMR data of a small RNA with the sequence of a conserved part of the ribosomal RNA of the large subunit is 1VOP (12).
www-unix.oit.umass.edu /~wdecatur/ribosome   (1615 words)

  
 CanB2 - Calcineurin B subunit, isoform 2   (Site not responding. Last check: 2007-10-08)
The gene canB2, which encodes the essential regulatory subunit of calcineurin, was identified as a suppressor group, demonstrating that the screen was capable of identifying genes relevant to calcineurin function.
CanB2 is a homologue of CanB (Calcineurin B subunit, isoform 1) from Drosophila melanogaster.
CanB2 is a homologue of Ppp3r1 (Calcineurin B subunit isoform 1) from Mus musculus.
www.pdg.cnb.uam.es /UniPub/iHOP/gg/69048.html   (174 words)

  
 At5g52340 - exocyst subunit EXO70 family protein   (Site not responding. Last check: 2007-10-08)
At5g52340 is a homologue of At2g28640 (exocyst subunit EXO70 family protein) from Arabidopsis thaliana.
At5g52340 is a homologue of At2g28650 (exocyst subunit EXO70 family protein) from Arabidopsis thaliana.
At5g52340 is a homologue of At2g39380 (exocyst subunit EXO70 family protein) from Arabidopsis thaliana.
www.ihop-net.org /UniPub/iHOP/gg/20584.html   (256 words)

  
 Postsynaptic clustering of major GABAA receptor subtypes requires the
receptor subunits is exactly juxtaposed to punctae immunoreactive for the presynaptic GABAergic marker glutamic acid decarboxylase (GAD) (Figs 1a, d, g and j and 2a) and to a subset of punctae immunoreactive for synaptophysin (Fig.
2 subunit (c−g) and gephyrin (a−d) or synaptophysin (e−g) and analyzed by confocal microscopy.
2 subunit (a) that are extensively colocalized with punctate staining for gephyrin (c).
www.nature.com /cgi-taf/DynaPage.taf?file=/neuro/journal/v1/n7/full/nn1198_563.html   (4824 words)

  
 A Novel Plant Ferritin Subunit from Soybean That Is Related to a Mechanism in Iron Release -- Masuda et al. 276 (22): ...
subunit identified in this study was not susceptible to cleavage.
subunit to be an iron releasing form (23, 25).
the H-2 subunit was not susceptible to cleavage of the C-terminal
www.jbc.org /cgi/content/full/276/22/19575   (4195 words)

  
 The {beta}1 subunit of the Ca2+-sensitive K+ channel protects against hypertension -- Nelson and Bonev 113 (7): 955 -- ...
subunit, which reflects a single amino acid substitution, has an even higher efficacy in enhancing the Ca -sensitivity of BK channels resulting in their gain-of-function.
The BK channel ß1 subunit gene is associated with human baroreflex and blood pressure regulation.
Gain-of-function mutation in the KCNMB1 potassium channel subunit is associated with low prevalence of diastolic hypertension.
www.jci.org /cgi/content/full/113/7/955   (1593 words)

  
 Mission-Swan Subunit Duty Station
It is bounded by the Bob Marshall Wilderness to the east, Highway 2 to the north, Highway 93 to the west and the Rattlesnake Wilderness to the south.
Much of the subunit in the valley bottoms and benchlands is heavily roaded, with as many as eight miles of logging road per square mile of forest land.
Although all of the lands within the subunit are occupied by grizzly bears, significant threats exist to the long term survival of bears here.
www.nrmsc.usgs.gov /NCDE_dutystationMS.htm   (1071 words)

  
 Energy-driven subunit rotation at the interface between subunit a and the c oligomer in the FO sector of Escherichia ...
Energy-driven subunit rotation at the interface between subunit a and the c oligomer in the FO sector of Escherichia coli ATP synthase -- Hutcheon et al.
Energy-driven subunit rotation at the interface between subunit a and the c oligomer in the F
subunits, an actin filament attached to the c ring was observed
www.pnas.org /cgi/content/full/98/15/8519   (4605 words)

  
 ATP Synthase: Fo Structures   (Site not responding. Last check: 2007-10-08)
The partial complex shown is composed of 12 c subunits and the membrane-spanning helices of subunit a (green).
The different subunit c conformations were determined using NMR of single subunits at pH 5 or pH 8.
Arg 210 from subunit a is located between the deprotonated Asp 61 ("COO-") of the blue subunit and the protonated Asp 61 ("COOH") of the adjacent purple subunit.
info.bio.cmu.edu /Courses/BiochemMols/Channels/1c17.htm   (763 words)

  
 At2g39380 - exocyst subunit EXO70 family protein   (Site not responding. Last check: 2007-10-08)
At2g39380 is a homologue of At2g28640 (exocyst subunit EXO70 family protein) from Arabidopsis thaliana.
At2g39380 is a homologue of At2g28650 (exocyst subunit EXO70 family protein) from Arabidopsis thaliana.
At2g39380 is a homologue of At3g09520 (exocyst subunit EXO70 family protein) from Arabidopsis thaliana.
www.pdg.cnb.uam.es /UniPub/iHOP/gg/3890.html   (274 words)

  
 At3g09520 - exocyst subunit EXO70 family protein   (Site not responding. Last check: 2007-10-08)
At3g09520 is a homologue of At2g28640 (exocyst subunit EXO70 family protein) from Arabidopsis thaliana.
At3g09520 is a homologue of At2g28650 (exocyst subunit EXO70 family protein) from Arabidopsis thaliana.
At3g09520 is a homologue of At3g55150 (exocyst subunit EXO70 family protein) from Arabidopsis thaliana.
www.pdg.cnb.uam.es /UniPub/iHOP/gg/5472.html   (254 words)

  
 AV/C CA Subunit Specification   (Site not responding. Last check: 2007-10-08)
The CA subunit is a stand-alone piece of functionality that is used to descramble selected scrambled services.
The CA Subunit provides the core functionality that is required to descramble selected services.
The CA Subunit supports commands that allow the user to select a service or group of services to be descrambled, assuming that they have entitlement, and to query a future service for entitlement.
www.1394ta.org /Technology/Specifications/Descriptions/AVC_CA_Subunit_10.htm   (94 words)

  
 InterPro: IPR008193 DNA-directed RNA polymerase, 13 to 16 kDa subunit
Small subunits of about 13 to 16 kDa are found in all three types of eukaryotic polymerases and in archaeal polymerase.
Subunits that belong to this family include: Rpb11 subunit from RNA polymerase II in eukaryotes [ 1, 2 ], subunit L from archaeal RNA polymerase [ 3 ] and subunit Rpc19 from RNA polymerases I and II in Saccharomyces cerevisiae [ 4 ].
Dequard-Chablat M. Riva M. Carles C. Sentenac A. RPC19, the gene for a subunit common to yeast RNA polymerases A (I) and C (III).
www.ebi.ac.uk /interpro/IEntry?ac=IPR008193   (3035 words)

  
 Methylation of the Protein Phosphatase 2A Catalytic Subunit Is Essential for Association of B{alpha} Regulatory Subunit ...
Methylation of the Protein Phosphatase 2A Catalytic Subunit Is Essential for Association of B{alpha} Regulatory Subunit But Not SG2NA, Striatin, or Polyomavirus Middle Tumor Antigen -- Yu et al.
Methylation of the Protein Phosphatase 2A Catalytic Subunit Is Essential for Association of B
Binding of different regulatory subunits and methylation of the catalytic (C) subunit carboxy-terminal leucine 309 are two
www.molbiolcell.org /cgi/content/abstract/12/1/185   (745 words)

  
 The Repertoire of Na,K-ATPase alpha and beta Subunit Genes Expressed in the Zebrafish, Danio rerio -- Rajarao et al. 11 ...   (Site not responding. Last check: 2007-10-08)
subunit clones 1a and 1b are orthologs of the
subunit genes appear to be orthologous to the mammalian
3 subunit maps to mouse chromosome 9, and a related gene, Atp1b3-rs, maps to mouse chromosome 3.
www.genome.org /cgi/content/full/11/7/1211   (4409 words)

  
 Endothelial K+ channel lacks the Ca2+ sensitivity-regulating {beta} subunit -- PAPASSOTIRIOU et al. 14 (7): 885 -- The ...
Correspondingly, mRNA expression of the ß subunit was
subunit in freshly isolated porcine aortic endothelial cells (PAEC), and in VSMC from porcine aorta (PAo) and porcine renal artery (PRA).
ß subunit cDNA was amplified by RT-PCR from VSMC of umbilical
www.fasebj.org /cgi/content/full/14/7/885   (4821 words)

  
 Archives of Pathology & Laboratory Medicine: Immunoexpression of inhibin (alpha) subunit, inhibin/activin (beta A) ...
Objective.-Anti-inhibin alpha and inhibin/activin beta A subunit and anti-CD99 monoclonal antibodies (mAbs) have recently been demonstrated to be able to label ovarian granufosa cells; thus, they may be of value in the diagnosis of granulosa cell tumors.
Ovarian cancer is the fourth most common cancer and the leading cause of death from gynecologic malignancy.1 Despite considerable efforts to elucidate the exact mechanisms by which growth and proliferation of both normal and malignant ovarian cells are regulated in the human ovary little is known.
This study is to further evaluate the utility of anti-inhibin alpha subunit, anti-inhibin/ activin beta A subunit mAb and anti-CD99 mAb far the differential diagnosis of ovarian tumors, especially between SCSTs and epithelial tumors.
www.findarticles.com /p/articles/mi_qa3725/is_200004/ai_n8890619   (655 words)

  
 Calcium Channel beta Subunit Promotes Voltage-Dependent Modulation of alpha 1B by Gbeta gamma -- Meir et al. 79 (2): ...
subunits is to enhance the coupling between depolarization and
The cumulative first latency (CFL) plots for all of the experiments with the same subunit composition were averaged, and the means ± SEM are shown.
subunit at three different voltages; the voltage step is indicated above each column.
www.biophysj.org /cgi/content/full/79/2/731   (5419 words)

  
 Embryonic Expression of the Putative gamma  Subunit of the Sodium Pump Is Required for Acquisition of Fluid Transport ...
Embryonic Expression of the Putative gamma  Subunit of the Sodium Pump Is Required for Acquisition of Fluid Transport Capacity during Mouse Blastocyst Development -- Jones et al.
Subunit of the Sodium Pump Is Required for Acquisition of Fluid Transport Capacity during Mouse Blastocyst Development
subunit is not concentrated in the basolateral surface of the
www.jcb.org /cgi/content/abstract/139/6/1545   (684 words)

  
 PKA beta (catalytic subunit) (phospho S338) antibody (ab5816) datasheet   (Site not responding. Last check: 2007-10-08)
If PKA beta (catalytic subunit) (phospho S338) antibody (ab5816) does not perform as described on this datasheet, notify us within 90 days of delivery using this form, so that we can help you or offer you a replacement or a refund.
PKA is composed of conserved catalytic subunits and regulatory subunits that dissociate upon activation by cAMP.
The catalytic subunit is assembled and expressed as an active form and is phosphorylated on threonine 197 by PDK 1 in the activation loop and serine 338 in the carboxyl terminus.
www.abcam.com /?datasheet=5816   (794 words)

  
 Mapping of Subunit-Subunit Contact Surfaces on the beta ' Subunit of Escherichia coli RNA Polymerase -- Katayama et al. ...
The RNA polymerase holoenzyme of Escherichia coli is composed of the core enzyme with the subunit composition of
Expression and Purification of Subunits and Subunit Fragments-- RNA polymerase subunits and their fragments were all expressed in E.
subunit is associated (holoenzyme form) or not (core enzyme form).
www.jbc.org /cgi/content/full/275/5/3583   (4592 words)

  
 Chaperone-Subunit-Usher Interactions Required for Donor Strand Exchange during Bacterial Pilus Assembly -- Barnhart et ...
groove of the subunit (7, 27, 44), stabilizing the subunit in
The genetic determinant of adhesive function in type 1 fimbriae of Escherichia coli is distinct from the gene encoding the fimbrial subunit.
Interactive surface in the PapD chaperone cleft is conserved in pilus chaperone superfamily and essential in subunit recognition and assembly.
jb.asm.org /cgi/content/full/185/9/2723   (5400 words)

  
 Ca2+ Channel beta 3 Subunit Enhances Voltage-Dependent Relief of G-Protein Inhibition Induced by Muscarinic Receptor ...
subunit coexpression on rate and voltage dependence of prepulse facilitation.
subunit liberated by activation of the muscarinic receptor.
subunit is responsible for channel inhibition by G protein-coupled receptors.
www.jneurosci.org /cgi/content/full/18/13/4883   (4195 words)

  
 Disparate Roles for the Regulatory A Subunit Isoforms in Arabidopsis Protein Phosphatase 2A -- Zhou et al. 16 (3): 709 ...
Proteins were extracted from parental wild-type, single, and double mutant seedlings after 7 d of growth in the dark and subjected to immunoblot analysis for A and C subunits (A) or for A subunits (B) as described in Figure 2.
Corum III,, J.W., Hartung, A.J., Stamey, R.T., and Rundle, S.J. Characterization of DNA sequences encoding a novel isoform of the 55 kDa B regulatory subunit of the type 2A protein serine/threonine phosphatase of Arabidopsis thaliana.
Kamibayashi, C., Lickteig, R.L., Estes, R., Walter, G., and Mumby, M.C. Expression of the A subunit of protein phosphatase 2A and characterization of its interactions with the catalytic and regulatory subunits.
www.plantcell.org /cgi/content/full/16/3/709   (6557 words)

  
 26S Proteasome subunit polyclonal antibodies from Research Diagnostics Inc
Background: Proteolytic degradation is critical to the maintenance of appropriate levels of short-lived and regulatory proteins as important and diverse as those involved in, cellular metabolism, heat shock and stress response, antigen presentation, modulation of cell surface receptors and ion channels, cell cycle regulation, transcription, and signalling factors.
To a lesser extent an 30kda protein is also detected which might correspond to a subunit degradation.
This sequence is 93% conserved in the rat and chicken and 87% conserved in the mouse protein.
www.researchd.com /miscabs/prot26s.htm   (1001 words)

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