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Topic: Sulfadiazine


In the News (Tue 2 Dec 08)

  
  Silver sulfadiazine - Wikipedia, the free encyclopedia
Silver sulfadiazine is a topical antibacterial used primarily on second- and third-degree burns.
The cream is kept applied to the burned skin at all times, for the duration of the healing period or until a graft is applied.
Silver sulfadiazine is typically delivered in a 1% solution suspended in a water-soluble base.
en.wikipedia.org /wiki/Silver_sulfadiazine   (145 words)

  
 SULFADIAZINE Faq
Sulfadiazine is an antibiotic which is a member of the sulfonamides or sulfa drugs.
Sulfadiazine is used to treat a variety of infections, including Toxoplasmosis, an infection of the brain.
The dose of sulfadiazine in adults is 2 to 8 g daily for 3 to 4 weeks, and in children 100-200mg/kg 4 for 3 to 4 weeks.
www.tthhivclinic.com /sulfad.htm   (788 words)

  
 MedlinePlus Drug Information: Silver Sulfadiazine (Topical)   (Site not responding. Last check: 2007-10-01)
Silver sulfadiazine (SILL-ver sul-fa-DYE-a-zeen), a sulfa medicine, is used to prevent and treat bacterial or fungus infections.
Silver sulfadiazine cream is applied to the skin and/or burned area(s) to prevent and treat bacterial or fungus infections that may occur in burns.
Silver sulfadiazine has not been shown to cause birth defects or other problems in studies in rabbits treated with 3 to 10 times the usual amount of silver sulfadiazine.
www.nlm.nih.gov /medlineplus/druginfo/uspdi/202521.html   (1166 words)

  
 sulfadiazine - Hartford, Connecticut CT
Sulfadiazine is used to treat infections such as urinary tract infections, toxoplasmosis, and others.
Sulfadiazine should be taken at evenly spaced intervals throughout the day and night to keep the amount of medication in the blood high enough to treat the infection.
Sulfadiazine may increase the sensitivity of the skin to sunlight.
www.saintfranciscare.com /19357.cfm   (944 words)

  
 silver sulfadiazine topical - [Medication]
Silver sulfadiazine topical is used to prevent and treat skin infections on areas of burned skin.
You may not be able to use silver sulfadiazine topical, or you may require a dosage adjustment or special monitoring during treatment.
Silver sulfadiazine topical is in the FDA pregnancy category B. This means that it is not expected to be harmful to an unborn baby.
www.peacehealth.org /kbase/multum/d01259a1.htm   (1034 words)

  
 [No title]
Sulfadiazine is also sometimes used in combination with
The usual dose of sulfadiazine is up to a total daily intake of 2-8 grams for adults and 100-200 mg/kg of body weight daily in children.
Sulfadiazine is most commonly given in combination with pyrimethamine.
www.critpath.org /aric/gloss/body/sulfadiazine.htm   (531 words)

  
 Sulfadiazine/Trimethoprim Sulfamethoxazole-Trimethoprim
Sulfadiazine occurs as an odorless or nearly odorless, white to slightly yellow powder.
The serum elimination half-lives for sulfadiazine in various species are: 9.84 hours (dogs), 2.71 hours (horses), 2.5 hours (cattle).
While trimethoprim is quite rapidly eliminated from the serum, the drug may persist for a longer period of time in tissues.
www.elephantcare.org /Drugs/sulfadia.htm   (2072 words)

  
 Silver - Wikipedia, the free encyclopedia
Colloidal silver is a possible antibacterial / antibiotic treatment espoused in alternative medicine, also notorious for causing argyria.
Silver nitrate (liquid) was a standard of care but was largely replaced by silver sulfadiazine cream (SSD Cream) which was generally the "standard of care" for the antibacterial/antibiotic treatment of serious burns until the late 1990's.
Now, other options such as silver coated dressings (activated silver dressings) are used in addition to SSD cream, and may present advantages such as pain reduction and capacity for treatment at home.
en.wikipedia.org /wiki/Silver   (2405 words)

  
 Toxoplasmosis: Encyclopedia of Medicine
Later in a pregnancy, if the fetus has contracted the disease, treatment with the antibiotic pyrimethamine (Dara-prim, Fansidar) or sulfonamides may be effective.
Babies born with toxoplasmosis who show symptoms of the disease may be treated with pyrimethamine, the sulfa drug sulfadiazine (Microsulfon), and folinic acid (an active form of folic acid).
To treat cases of toxoplasmosis in immunocompromised AIDS patients, a combination of pyrimethamine and a sulfa-based drug, either sulfadiazine or clindamycin (Cleocin), have been used together and can be effective in treating this disease.
health.enotes.com /medicine-encyclopedia/toxoplasmosis   (1256 words)

  
 Sulfadiazine - Drugs & Vitamins - Drug Library - DrugDigest
Sulfadiazine stops the growth of certain bacteria and other organisms.
If you get an unusual reaction, stop using sulfadiazine at once and call your prescriber or health care professional for advice.
If you are going to have surgery, tell your prescriber or health care professional that you are using sulfadiazine.
www.drugdigest.org /DD/DVH/Uses/0,3915,763|Sulfadiazine,00.html   (692 words)

  
 Clinical Trial: Pyrimethamine, Sulfadiazine, and Leucovorin in Treating Patients With Congenital Toxoplasmosis
Giving the antiparasitic drugs pyrimethamine and sulfadiazine is standard treatment for congenital toxoplasmosis, but it is not yet known which regimen of pyrimethamine is most effective for the disease.
One group of infants is treated with a loading dose of oral pyrimethamine followed by a higher dose for the first two months then a lower dose for the remainder of the 12 months.
Sulfadiazine and leucovorin calcium are also given orally for 12 months.
www.clinicaltrials.gov /show/NCT00004317   (403 words)

  
 MedlinePlus Drug Information: Sulfadiazine
Sulfadiazine, a sulfa drug, eliminates bacteria that cause infections, especially urinary tract infections.
tell your doctor and pharmacist if you are allergic to sulfadiazine, any other sulfa drugs, diuretic (''water pills''), oral diabetes medications, or any other drugs.
Sulfadiazine may make your skin sensitive to sunlight.
www.nlm.nih.gov /medlineplus/druginfo/medmaster/a682130.html   (573 words)

  
 Drugs and Treatments - Silver Sulfadiazine Top - (Silvadene) - Patient Handout from WebMD
Silver sulfadiazine belongs to a class of drugs known as topical antibiotics.
Before using silver sulfadiazine, tell your doctor or pharmacist if you are allergic to it; or to other sulfa antibiotics; or if you have any other allergies.
Silver sulfadiazine should not be used to treat premature babies or newborns during the first 2 months of life.
webmd.com /drugs/drug-13530-Silver+Sulfadiazine+Topical.aspx?...   (1083 words)

  
 Pharmacokinetics of BID vs. QID dosing of sulfadiazine in HIV-infected patients
Subjects with significant cardiac, pulmonary, or renal disease or other serious illness will be excluded if, in the judgment of the investigator, their safety or the integrity of the study might be compromised by their enrollment.
Patients will receive sulfadiazine for five days followed by an eight-day washout period and then will receive sulfadiazine again at the alternate dosage schedule.
Sulfadiazine has been in clinical use in the United States for over 40 years.
www.niaid.nih.gov /dir/labs/lir/hiv/sdz.htm   (499 words)

  
 Healthopedia.com - Sulfadiazine (Oral) - Drugs Information, Side Effects, & Interactions
Before taking sulfadiazine tell your doctor if you have anemia or other blood problems, asthma or severe allergies, liver disease, kidney disease, G-6-PD (glucose-6-phosphate dehydrogenase) deficiency.
Sulfadiazine should not be taken during the last 3 months of a pregnancy.
While you are taking this medicine, your doctor may want to check your blood at regular intervals.
www.healthopedia.com /drugs/quick/sulfadiazine   (594 words)

  
 Silvadene Online, Description, Chemistry, Ingredients, Blackbox - Silver Sulfadiazine - RxList Monographs
Silver sulfadiazine cream 1% is a soft, white, water-miscible cream containing the antimicrobial agent silver sulfadiazine in micronized form, which has the following structural formula:
The cream vehicle consists of white petrolatum, stearyl alcohol, isopropyl myristate, sorbitan monooleate, polyoxyl 40 stearate, propylene glycol, and water, with methylparaben 0.3% as a preservative.
Silver sulfadiazine cream 1% spreads easily and can be washed off readily with water.
www.rxlist.com /cgi/generic3/silversulf.htm   (123 words)

  
 Silver sulfadiazine: an overview
Silver sulfadiazine ointment is applied after prompt emergency treatment and debridement of burns.
It is applied relatively thickly (1-2 mm) and does not need to be covered by dressings and so can be used under less than ideal conditions.
It has been found that prompt treatment of sulfur mustard by irrigation with povidone iodine and treatment with silver sulfadiazine can limit the effects of mustard exposure.
www.cbwinfo.com /Pharmaceuticals/Sulfadiazine.html   (268 words)

  
 Thermazene - Drugs & Vitamins - Drug Library - DrugDigest
As a cream it is used on the skin for second- or third-degree burns to prevent or treat serious infection.
Silver sulfadiazine cream is for external use only.
Burnt areas should be covered with silver sulfadiazine cream at all times.
www.drugdigest.org /DD/DVH/Uses/0,3915,607|Thermazene,00.html   (545 words)

  
 Silver Sulfadiazine (Silvadene) - Wheeless' Textbook of Orthopaedics
- silver sulfadiazine is painless on application (and is often soothing) and causes no acid base abnormalities;
Comparison of silver sulfadiazine, povidone-iodine and physiologic saline in the treatment of chronic pressure ulcers.
In vivo and in vitro antimicrobial activity of silver sulfadiazine and cerium nitrate.
www.wheelessonline.com /ortho/silver_sulfadiazine_silvadene   (280 words)

  
 Gaia Research - Colloidal Silver Part 1
In atomic absorption spectrophotometric monitoring of silver levels in silver sulfadiazine cream treated burn patients, the concentrations of silver in subjects without industrial or medical exposure was less than 2.3 ug/L in the and 2 ug/Day in .
In silver sulfadiazine (SSD.cream treated patients, concentrations reached a maximum of 310 ug/L and in , a maximum of 400 ug/Day.
Although silver sulfadiazine has been used extensively as an effective topical antimicrobial agent in thermal injury patients, little is known about the cutaneous absorption of the silver moiety in these patients.
www.gaiaresearch.co.za /silver.html   (5070 words)

  
 Sulfadiazine
If you have an allergy to any sulfa medicine, sulfadiazine, or any other part of the medicine.
Do not give to children less than 2 years of age except if they have congenital toxoplasmosis.
Sulfadiazine affects a vitamin called folic acid and its activity in bacteria causing destruction of its metabolic function in the bacteria.
www.umm.edu /altmed/ConsDrugs/Sulfadiazinecd.html   (383 words)

  
 Veterinary Products... sulfadiazine
This provides 250 mg of trimethoprim and 1250 mg of sulfadiazine per 110 lbs body weight.
The product should be administered once daily in a small amount of palatable feed for five to seven days or for two or three days after clinical symptoms have subsided.
Agency Conclusions This ANADA submitted under section 512(b) of the Federal Food, Drug, and Cosmetic Act satisfies the requirements of section 512(n) of the Act and demonstrates that when Tucoprim ® Powder (sulfadiazine and trimethoprim oral powder) is used under the proposed conditions of use, it is safe and effective for its labeled indications.
www.betterchem.com /vet/sulfadiazine.htm?zoom_highlight=chemical+co   (422 words)

  
 Twice-Weekly Maintenance Therapy with Sulfadiazine-Pyrimethamine To Prevent Recurrent Toxoplasmic Encephalitis in ...
of toxoplasmic encephalitis [8], a twice-weekly regimen of sulfadiazine
The activity of atovaquone (566C80) in murine toxoplasmosis is markedly augmented when used in combination with pyrimethamine or sulfadiazine.
Synergistic activity of azithromycin and pyrimethamine or sulfadiazine in acute experimental toxoplasmosis.
www.annals.org /cgi/content/full/123/3/175   (3158 words)

  
 Sulfadiazine - Wikipedia, the free encyclopedia
Side effects reported for Sulfadiazine include nausea, upset stomach, or loss of appetite; dizziness;
Lantrisul; Neotrizine; Sulfa-Triple #2; Sulfadiazine; Sulfaloid; Sulfonamides Duplex; Sulfose; Terfonyl; Triple Sulfa; Triple Sulfas; Triple Sulfoid
This page was last modified 20:31, 17 August 2006.
en.wikipedia.org /wiki/Sulfadiazine   (87 words)

  
 PetPlace.com - Article: Trimethoprim/Sulfadiazine (Tribrissen®)
that becomes even more effective when combined with a sulfonamide (sulfa drug), such as sulfadiazine and sulfamethoxazole.
Trimethoprim plus sulfadiazine and trimethoprim plus sulfamethoxazole are the most often-used combinations in veterinary medicine.
These are similar in antibiotic function and may be used interchangeably.
www.petplace.com /articles/artPrinterFriendly.asp?conID=19100   (497 words)

  
 Sulfadiazine-associated nephrotoxicity in patients with the acquired immunodeficiency syndrome.
Correspondingly, the cumulative sulfadiazine dose at manifestation doubled in AIDS patients with a median of 84 g versus 40 g in controls.
The principle aim of therapy in these patients is to (re)institute the physicochemical urinary solubility of sulfadiazine and its metabolites.
For this purpose, forced rehydration and, most importantly, urine alkalinization proved to be effective measures without an absolute need to withhold the drug.
www.aegis.com /aidsline/1996/nov/M96B1749.html   (503 words)

  
 EPA: Federal Register: Oral Dosage Form New Animal Drugs; Trimethoprim and Sulfadiazine Oral Paste
Administer orally as a single daily dose for 5 to 7 days: (i) 5 g of paste (335 mg trimethoprim and 1,665 mg sulfadiazine) per 150 pounds (68 kilograms) of body weight per day.
(ii) 3.75 g of paste (250 mg trimethoprim and 1,250 mg sulfadiazine) per 110 pounds (50 kilograms) of body weight per day.
For use where systemic antibacterial action against sensitive organisms is required during treatment of acute strangles, respiratory infections, acute urogenital infections, and wound infections and abscesses.
www.epa.gov /fedrgstr/EPA-IMPACT/2006/May/Day-31/i8303.htm   (589 words)

  
 Consumer Reports Medical Guide - Silver Sulfadiazine
Silver sulfadiazine, a sulfa drug, is used to prevent and treat infections of second- and third-degree burns.
Silver sulfadiazine usually is applied once or twice a day.
Do not let silver sulfadiazine get into your eyes, nose, or mouth, and do not swallow it.
consumerreports.org /mg/drug-reports/silver-sulfadiazine.htm   (625 words)

  
 Silver Sulfadiazine (Topical) - MayoClinic.com
It is not known whether silver sulfadiazine applied to the skin and/or burns passes into the breast milk.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur.
The presence of other medical problems may affect the use of silver sulfadiazine.
www.mayoclinic.com /health/drug-information/DR202521   (1183 words)

  
 EPM Treatment Pyrimethamine and Sulfadiazine Combination for Horses
Pyrimethamine is an anti-protozoal drug and sulfadiazine is a sulfa antibiotic.
Pyrimethamine should be used with extreme caution in animals with blood dyscrasias or bone marrow suppression.
• Because pyrimethamine and sulfadiazine combination have caused leukopenia, thrombocytopenia, and anemias, the regular monitoring of peripheral blood work is suggested.
www.wedgewoodpharmacy.com /monographs/pyrimethamine.asp   (728 words)

  
 sulfadiazine - [Medication]
What is the most important information I should know about sulfadiazine?
Ask your pharmacist any questions you have about this medication, especially if it is new to you.
Healthwise disclaims any liability for the decisions you make based on this information.
www.peacehealth.org /kbase/multum/d00118a1.htm   (962 words)

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