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Topic: Surface plasmon resonance

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	Patent 5898503: Surface plasmon resonance sensor with interchangeable optical element
		The surface plasmon detector of claim 2 wherein said path discontinuity minimizing means includes contouring of the surfaces of said base and said housing so that any radiation from said source passes through the surfaces of said base and said housing in a direction substantially normal to the surface through which it passes.
		The resonance angle is determined by directing a polarized light beam through the prism onto the surface with the metal film thereon and measuring the intensity of the light reflected therefrom and through an external surface of the prism.
		The basis for the use of surface plasmon resonance for sensing is the fact that the oscillation of a surface-plasma of free electrons which exists at a conductor-dielectric boundary is affected by the refractive index of the material adjacent the conducting film surface on the side thereof opposite the prism.
	www.freepatentsonline.com /5898503.html (3810 words)

	Surface plasmon resonance biosensor for measurement of anti-glycolipid antibody levels in neuropathy - US Patent 6730487 (Site not responding. Last check: 2007-11-05)
		The method of claim 3, wherein the control surface plasmon resonance value comprises the signal detected from the surface of the sensor chip coated with a selected control antigen, wherein the chip is also alternatively exposed to the solution being evaluated for anti-antigen antibodies.
		A method of claim 1, wherein the surface plasmon resonance signal is increased by washing the solution from the surface of the sensor chip and applying a second solution containing a secondary antibody to the surface.
		In one embodiment the antigen coated surface is a glycolipid-coated surface.
	www.patentstorm.us /patents/6730487.html (5009 words)

	More on surface plasmons (Site not responding. Last check: 2007-11-05)
		Surface plasmons are a subset of these 'eigen-modes' of the electrons, which are bound to regions in the material where the optical properties reverse, i.e.
		We currently use this resonant effect as a means of probing the optical properties of materials (high temperature superconductors, niobium and platinum silicide are on the agenda at present) and of enhancing the response of photodetectors and the effects of laser ablation.
		Surface Plasmons cannot couple directly to free-space electromagnetic radiation of the same energy because they travel too slowly, their associated wavevector being too large to satisify conservation of energy and momentum.
	www.qub.ac.uk /mp/con/plasmon/sp1.html (400 words)

	High Resolution Surface Plasmon Resonance Spectroscopy (Site not responding. Last check: 2007-11-05)
		Surface Plasmon Resonance (SPR) technique has emerged as a powerful technique for a variety of chemical and biological sensor applications.
		Surface plasmons are collective oscillations of free electrons in a metallic film.
		Because the resonant condition is extremely sensitive to the refractive index of the medium adjacent to the metal film, adsorption of molecules on the metallic film or conformational changes in the adsorbed molecules can be accurately detected.
	www.public.asu.edu /~ntao1/SPR.htm (184 words)

	Imaging of Cell/Substrate Contacts of Living Cells with Surface Plasmon Resonance Microscopy -- Giebel et al. 76 (1): ...
		The lower surface of the cells is simultaneously investigated with surface plasmon microscopy.
		the halfwidth of the resonance, being inversely proportional to
		The dashed line in D is a fit to the undisturbed surface plasmon curve of the bare substrate and is replotted in E and F as a reference.
	www.biophysj.org /cgi/content/full/76/1/509 (4132 words)

	Texas Instruments Sensors - Spreeta Biosensor (Spreeta is a low cost Surface Plasmon Resonance, SPR based biosensing ...
		SPR (Surface Plasmon Resonance) is a proven technology used to obtain the most detailed biomolecular binding information available.
		Spreeta operating principle: Light from an LED is reflected from a gold surface and the angle and intensity of the SPR minimum is measured.
		The gold surface can be covered with a biofilm, customized for essentially any molecule for which detection is desired.
	www.zhdanov.ru /classified-catalogue/t-companies/texas_instruments.htm (689 words)

	Evaluation of MafG interaction with Maf recognition element arrays by surface plasmon resonance imaging technique -- ...
		Evaluation of MafG interaction with Maf recognition element arrays by surface plasmon resonance imaging technique -- Kyo et al.
		Articles by Kyo, M. Articles by Yamamoto, M. Evaluation of MafG interaction with Maf recognition element arrays by surface plasmon resonance imaging technique
		surface is effective for preventing nonspecific adsorption and
	www.genestocellsonline.org /cgi/content/abstract/9/2/153 (338 words)

	APS - 2005 APS March Meeting PostDeadline - Event - Ultrafast evolution of the surface plasmon resonance in vanadium ... (Site not responding. Last check: 2007-11-05)
		The signature of the MIT is the appearance of the surface plasmon resonance (SPR) in the near-infrared.
		Femtosecond measurements of the temporal evolution of the SPR in VO$_{2}$ nanoparticles show that it is fully formed no later than 200 fs following excitation by a 100 fs laser pulse that initiates a band-to-band excitation.
		The wavelength dependence of the SPR generally follows Mie theory and agrees with the SPR spectrum observed when the MIT is initiated by slow heating.
	meetings.aps.org /Meeting/MAR05/Event/22041 (213 words)

	Competitive protein adsorption as observed by surface plasmon resonance (Site not responding. Last check: 2007-11-05)
		The adsorption from blood plasma solutions of albumin, fibrinogen and immunoglobulin-G (IgG), to a polystyrene surface was investigated as part of concentration- and time-dependent studies, to observe the sequential adsorption of the three proteins at the surface.
		Adsorption of plasma solutions at a range of concentrations or incubation times was performed and the resulting surfaces were probed by the addition of an appropriate antibody to the protein surface.
		The SPR was able to detect changes in the relative surface concentration of each component demonstrating that the protein's residence time at the interface was dependent upon its molecular weight, bulk concentration and surface affinity.
	www.nottingham.ac.uk /%7Epazxc/publications/1999/1999a001.htm (181 words)

	Characterization of heparin binding by a peptide from amyloid P component using capillary electrophoresis, surface ... (Site not responding. Last check: 2007-11-05)
		Characterization of heparin binding by a peptide from amyloid P component using capillary electrophoresis, surface plasmon resonance and isothermal titration calorimetry -- Hernaiz et al.
		Characterization of heparin binding by a peptide from amyloid P component using capillary electrophoresis, surface plasmon resonance and isothermal titration calorimetry
		electrophoresis (CE), surface plasmon resonance (SPR), and isothermal
	www.ejbiochem.org /cgi/content/full/269/12/2860 (4249 words)

	Evaluation of MafG interaction with Maf recognition element arrays by surface plasmon resonance imaging technique -- ...
		Jordan, C.E. and Corn, R.M. (1997) Surface plasmon resonance imaging measurements of electrostatic biopolymer adsorption onto chemically modified gold surfaces.
		Oda, M., Furukawa, K., Sarai, A. and Nakamura, H. (1999) Kinetic analysis of DNA binding by the c-Myb DNA-binding domain using surface plasmon resonance.
		Seimiya, M. and Kurosawa, Y. (1996) Kinetics of binding of Antp homeodomain to DNA analyzed by measurements of surface plasmon resonance.
	www.genestocellsonline.org /cgi/content/full/9/2/153 (5376 words)

	Surface Plasmon Resonance Publications - Georgiadis Group
		"Electrostatic surface plasmon resonance: Direct electric field-induced hybridization and denaturation in monolayer nucleic acid films and label-free discrimination of base mismatches", Richard J. Heaton, Alexander W. Peterson and Rosina M. Georgiadis, (Proc Natl Acad Sci U S A. "Kinetic control of hybridization in surface immobilized DNA monolayer films", Peterson AW, Heaton RJ, Georgiadis R,(J. Am.
		"Surface plasmon resonance spectroscopy as a probe of in-plane polymerization in monolayer organic conducting films",Georgiadis R, et al.
		"In situ kinetics of self-assembly by surface plasmon resonance spectroscopy", K. Peterlinz and R. Georgiadis, (Langmuir, 12, 4731-4740 (1996).
	people.bu.edu /rgeorgia/papers.htm (277 words)

	Surface Plasmon Resonance (Site not responding. Last check: 2007-11-05)
		The surface plasmon (SP) wave on the gold surface is modulated from the dielectric constant of the thin gold film and the dielectric constant of the molecules adsorbed on the surface and within 200-300nm away of the surface.
		The position of the minima is indicative of the chemistry on the surface.
		The shift for the minimum wavelength is a measure of the dielectric constant or refractive index change on the gold surface.
	www.public.asu.edu /~booksh/spr2.htm (587 words)

	Surface plasmon resonance studies of wild-type and AV77 tryptophan repressor resolve ambiguities in super-repressor ...
		Surface plasmon resonance studies of wild-type and AV77 tryptophan repressor resolve ambiguities in super-repressor activity
		Resonance units were measured when the binding approached equilibrium, ~3 min after the start of the protein injection.
		Oda, M., Furukawa, K., Sarai, A., and Nakamura, H. Kinetic analysis of DNA binding by the c-Myb DNA-binding domain using surface plasmon resonance.
	www.proteinscience.org /cgi/content/full/12/8/1613 (3834 words)

	Surface plasmon resonance (Site not responding. Last check: 2007-11-05)
		Surface plasmon resonance is a detection technology applied in biosensors
		An improved coating for the isolation and quantitation of interferon-gamma in spiked plasma using surface plasmon resonance (SPR).
		Evaluation of the limits of resonance tunability in metallic nanoshells with a spectral averaging method.
	www.biosensor.co.uk /Surface_plasmon_resonance.html (478 words)

	Surface Plasmon Resonance Analysis of Antipolysaccharide Antibody Specificity: Responses to Meningococcal Group C ...
		SPR sensorgrams of MCPS binding with four murine anti-MCPS MAbs, C2/1076.10, C2/655.7, 2016.3, and 2055.5, with different FELISA specificities.
		Determination of kinetic constants for the interaction between a monoclonal antibody and peptides using surface plasmon resonance.
		Surface immunoglobulin D as a functional receptor for a subclass of B lymphocytes.
	iai.asm.org /cgi/content/full/72/6/3451 (5592 words)

	APS - 2005 APS March Meeting PostDeadline - Event - An alternative mechanism for surface enhanced spectroscopy: second ... (Site not responding. Last check: 2007-11-05)
		It is identified that the luminescence involves radiative recombination of electrons in band 6 (sp conduction band) with holes in band 4 (secondary top d band), near the L symmetry point.
		We show that the strong emission is a consequence of the second harmonic surface plasmon resonance (SHSPR), which is an inherent nature of metallic nanoparticles with high density of surface plasmons.
		However, for SHSPR we only need a dim pumping source, which is used to trigger the second harmonic absorption of very dense quantum particles, such as surface plasmons in Au nanoclusters.
	meetings.aps.org /Meeting/MAR05/Event/27352 (269 words)

	SPR Pages - introduction (2)
		Surface Plasmon Resonance (SPR) is a powerful technique to measure biomolecular interactions in real-time in a label free environment.
		While one of the interactants is immobilized to the sensor surface, the other are free in solution and passed over the surface.
		In addition, the binding of two interactants can be used to measure the concentration of one of the interactants after making a calibration curve.
	home.hccnet.nl /ja.marquart/SPRpages.htm (151 words)

	Interaction of the Crystalline Bacterial Cell Surface Layer Protein SbsB and the Secondary Cell Wall Polymer of ...
		Panel C depicts the simulated response surface and corresponding residuals resulting from fitting of the model for bivalent binding to fixed ligands (27) to the data for SCWP binding to immobilized 3SLH (A).
		Panel C depicts the simulated response surface and corresponding residuals resulting from fitting of the heterogeneous-ligand model for three parallel reactions to the data for 3SLH binding to immobilized SCWP (A).
		Quantitative determination of surface concentration of protein with surface plasmon resonance using radiolabeled proteins.
	jb.asm.org /cgi/content/full/186/6/1758 (7055 words)

	Kinetic analysis of estrogen receptor/ligand interactions -- Rich et al. 99 (13): 8562 -- Proceedings of the National ...
		Surface plasmon resonance biosensor technology was used to directly measure the binding interactions of small molecules to
		SPR biosensor experiments require immobilizing one reactant on a surface and monitoring its binding to a second reactant in
		Surface plasmon resonance analyses were performed by using Biacore 2000 and Biacore 3000 optical biosensors equipped with
	www.pnas.org /cgi/content/full/99/13/8562 (3507 words)

	Surface Plasmon Resonance-BIAcore
		Surface plasmon resonance (SPR) is an optical phenomenon that is used to measure changes in the solution concentration of molecules at a biospecific surface.
		The interacting protein of interest is injected over the surface and the kinetics of binding are measured in real time.
		SPR is a relatively new method for characterizing protein-protein interactions.
	www.med.unc.edu /wrkunits/2depts/biochem/MACINFAC/biacore.html (445 words)

	Institut de Biologie structurale - Biacore’s Surface Plasmon Resonance technology
		In a Biacore experiment, one of the interacting molecule is bound to the biosensor surface (sensor chip), whereas the other is delivered to the surface in a continuous flow through a microfluidic system.
		Binding to the immobilized molecule is followed by surface plasmon resonance, which detects the mass concentrations at the surface.
		The response is directly proportional to the mass of molecules that bind to the surface.
	www.ibs.fr /content/ibs_eng/presentation/platform/Facilities/biacore.htm (307 words)

	J. Biochem. 130, pp. 553-559 (2001)[body text]
		Surface plasmon resonance (SPR) detectors, such as the BIAcore (Amersham-Pharmacia), allow the direct visualization of these macromolecular interactions in real-time, and thus provide kinetic information in addition to the equilibrium binding constants.
		These deviations may be attributed to limitation of the mass transport from the bulk solution to the sensor surface or inhomogeneity of the binding sites (13).
		In this case the extent of deviation from pseudo-first-order kinetics should increase with increasing analyte concentration or surface ligand density (15)--as the surface ligand density increases, so the number of ligand molecules attached to sites deep within the gel will increase, giving a corresponding increase in the proportion of low affinity sites.
	wwwsoc.nii.ac.jp /jbiochem/jb/130-4/4faavhtx.htm (3465 words)

	Selection of functional T cell receptor mutants from a yeast surface-display library -- Kieke et al. 96 (10): 5651 -- ...
		Expression of properly folded wild-type 2C scTCR on the surface of the yeast could not be detected with 1B2 (Fig.
		Peak mean fluorescence and the percentage of the population that was positive (i.e., within the region of the cursor bar) are indicated.
		Finally, there are many proteins that have inherent difficulties in expression as fusion proteins on the surface of phage.
	www.pnas.org /cgi/content/full/96/10/5651 (3636 words)

	Examination of the Kinetics of Herpes Simplex Virus Glycoprotein D Binding to the Herpesvirus Entry Mediator, Using ...
		SPR was done to characterize the binding between HveA, a receptor for HSV entry, and gD, the HSV receptor-binding protein
		Kinetic analysis of synthetic analogues of linear-epitope peptides of glycoprotein D of herpes simplex virus type 1 by surface plasmon resonance.
		A surface plasmon resonance assay for the binding of influenza virus hemagglutinin to its sialic acid receptor.
	jvi.asm.org /cgi/content/full/72/7/5937 (7090 words)

	Publication $pid (Site not responding. Last check: 2007-11-05)
		The size evolution of the surface plasmon resonance was investigated for free and embedded silver particles between about 2 to 10 nm in size.
		Based on this, a model was presented by combining the lattice contraction of particles and the free path effect of electrons to predict the size evolution of the resonance.
		This surface plasmon resonance shift proceeds linearly with reciprocal size for Ag particles in vacuum and argon, but for Ag particles embedded in glass it appears to be independent of the radius down to nearly 1 nm.
	www.mpi-halle.mpg.de /mpi/publi/go/2001/abs_pdf/319_01.html (218 words)

	SPR
		The sensor surface is a Au/Cr film of 41/2 nm thickness, prepared by Thermal Evaporation at Ultra High Vacuum (UHV) onto microscope glasses.
		The metalized glass is adhered to the prism using a matching oil with the same refractive index (n=1.52).
		The antibody-antigen interaction generates a change in the refractive index, and measuring at a fixed angle an increment of the SPR signal is observed
	www.imm.cnm.csic.es /biosensores/spr.htm (398 words)

	Herpesviruses and heparan sulfate: an intimate relationship in aid of viral entry -- Shukla and Spear 108 (4): 503 -- ...
		on the presence of cell surface heparan sulfate (33, 34).
		A cell surface protein with herpesvirus entry activity (HveB) confers susceptibility to infection by mutants of herpes simplex virus type 1, herpes simplex virus type 2 and pseudorabies virus.
		Examination of the kinetics of herpes simplex virus glycoprotein D binding to the herpesvirus entry mediator, using surface plasmon resonance.
	www.jci.org /cgi/content/full/108/4/503 (6412 words)

	A Molecular Basis for Functional Peptide Mimicry of a Carbohydrate Antigen -- Luo et al. 275 (21): 16146 -- Journal of ...
		The surface density was 1000 RU, the flow 20 µl/min, and the contact time was 7 min.
		It is possible that LeY, expressed on tumor cell surfaces, is displayed as "oligosaccharide patches" or as "clustered" epitopes.
		Using surface plasmon resonance methods we assessed the kinetics of binding of K61104 and K61107 peptides to BR55-2 (Fig.
	www.jbc.org /cgi/content/full/275/21/16146 (5008 words)

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