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Topic: Sympathomimetic

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In the News (Wed 24 Apr 19)

  Sympathomimetics - Wikipedia, the free encyclopedia
Sympathomimetics are a class of drugs whose properties mimic those of a stimulated sympathetic nervous system.
Sympathomimetics include the naturally occurring substances adrenaline (epinephrine), noradrenaline (norepinephrine), and other catecholamines such as dopamine, as well as the synthetic drugs pseudoephedrine, phenylephrine, and phenylpropanolamine.
In medicine, they are commonly prescribed in cardiac emergencies including shock and anaphylaxis, in some cases for weight loss, and in cold remedies, where they shrink swollen membranes in the upper respiratory tract.
en.wikipedia.org /wiki/Sympathomimetic   (139 words)

 Pan American Laboratories - Product Information
Sympathomimetic amines are contraindicated in patients with severe hypertension, severe coronary artery disease and patients on monoamine oxidase (MAO) inhibitor therapy.
Sympathomimetic amines should be used judiciously and sparingly in patients with hypertension, diabetes, ischemic heart disease, hyperthyroidism, increased intraocular pressure, and prostatic hypertrophy.
Sympathomimetic amines have been associated with certain untoward reactions including fear, anxiety, tenseness, restlessness, tremor, weakness, pallor, respiratory difficulty, dysuria, insomnia, hallucinations, convulsions, CNS depression, arrythmias, and cardiovascular collapse with hypotension.
pamlab.com /products/cc/pannaz_hc_insert.shtml   (976 words)

 Pan American Laboratories - Product Information
Sympathomimetic amines are contraindicated in nursing mothers and in patients with severe hypertension, severe coronary artery disease and patients on monoamine oxidase (MAO) inhibitor therapy (see Drug Interactions section).
Sympathomimetic amines should be used with caution in patients with hypertension, iscemic heart disease, diabetes mellitus, increased introcular pressure, hyperthyroidism or prostatic hypertrophy.
Sympathomimetics have been associated with certain untoward reactions including fear, anxiety, nervousness, restlessness, tremor, weakness, pallor, respiratory difficulty, dysuria, insomnia, hallucinations, convulsions, CNS depression, arrhythmias, and cardiovascular collapse with hypotension.
www.pamlab.com /products/cc/panmist_la_insert.shtml   (2031 words)

 AllRefer.com - sympathomimetic drug (Pharmacology) - Encyclopedia
sympathomimetic drug[simpath´´Omimet´ik] Pronunciation Key, any of a group of substances whose actions resemble the response of stimulated sympathetic nerves (see nervous system).
These drugs include epinephrine and other catecholamines that are naturally produced in the body, and chemically similar substances such as ephedrine.
Sympathomimetic drugs excite the central nervous system and heart and affect the diameter of blood vessels.
reference.allrefer.com /encyclopedia/S/sympatho.html   (189 words)

 eMedicine - Toxicity, Sympathomimetic : Article by Paul Kolecki, MD   (Site not responding. Last check: 2007-10-22)
In most cases, clinical poisoning by one sympathomimetic agent is indistinguishable from that of a second sympathomimetic agent with a different mechanism of action.
Some of the illegal sympathomimetic agents are more commonly abused by the inhalational route (eg, crack cocaine, methamphetamine) or the IV route (eg, cocaine, methamphetamine, methcathinone) than by the oral route.
Sympathomimetic toxicity is frequently associated with significant agitation, thus necessitating the use of physical restraints and chemical sedation.
www.emedicine.com /emerg/topic562.htm   (3275 words)

 Sympathomimetic Intoxication   (Site not responding. Last check: 2007-10-22)
Amphetamine or sympathomimetic intoxication describes the state that occurs with the use of...
Amphetamine or Sympathomimetic Intoxication (Intoxication - Amphetamines or Sympathomimetics, Intoxication - Uppers, Sympathomimetic Intoxication)...
Sympathomimetic intoxication; Intoxication - amphetamines or sympathomimetics; Intoxication - uppers...
www.sympathomimeticintoxication.info   (541 words)

 Inotropic / chronotropic drugs:   (Site not responding. Last check: 2007-10-22)
The sympathomimetic amines are traditionally classified according to their activity at alpha, beta
The sympathomimetics act by stimulating the synthesis of the 'second messenger' cyclic AMP (cAMP).
All of the sympathomimetic drugs noted here have very short half lives and must therefore be given by constant infusion.
www.manbit.com /PAC/chapters/P34.cfm   (2073 words)

 PHARMACOLOGY OF CATECHOLAMINES AND SYMPATHOMIMETIC DRUGS, 1998   (Site not responding. Last check: 2007-10-22)
This may be due to its ability to suppress sympathomimetic symptoms of withdrawal.
Amphetamine is an indirectly acting sympathomimetic which causes release of NE from adrenergic nerve endings, and also blocks its reuptake into the cytoplasm of the nerve terminal.
Its spectrum of effects is similar to EPI, another sympathomimetic with both alpha and beta agonist effects, however it has a longer duration of effect.
www.med.howard.edu /pharmacology/handouts/autono3.htm   (3280 words)

 MedlinePlus Drug Information: Appetite Suppressants, Sympathomimetic (Systemic )   (Site not responding. Last check: 2007-10-22)
Sympathomimetic appetite suppressants are used in the short-term treatment of obesity.
However, use of sympathomimetic appetite suppressants during breast-feeding is not recommended, because it may cause unwanted effects in nursing babies.
Sympathomimetic appetite suppressants may cause dryness of the mouth.
www.nlm.nih.gov /medlineplus/druginfo/uspdi/202069.html   (2364 words)

 Phentermine--Buy Phentermine--Order Phentermine online--where to buy Phentermine   (Site not responding. Last check: 2007-10-22)
Sympathomimetic appetite suppressants (Phentermine) are used in the short-term treatment of obesity.
It is not known if other sympathomimetic appetite suppressants pass into breast milk.
However, since all of the sympathomimetic appetite suppressants are similar, any of the above side effects may occur with any of these medicines.
www.phentermine.48xu.com   (2235 words)

 [No title]
sympathomimetic agent is to be used at a fixed dosage and preferably only as maintenance medication (in addition to the inhaled glucocorticoid).
sympathomimetic agent by spacer (4-10 puffs, spray one puff at a time and inhale 5 times), or subcutaneously if necessary (1 ml of 0.5 mg/ml), or via an electric-powered jet nebulizer (0.5-1 ml of 5 mg/ml).
sympathomimetic agents has been observed to increase bronchial sensitivity to irritants; apart from that, the bronchodilatory effect is sustained.
nhg.artsennet.nl /upload/104/guidelines2/E27b.htm   (9057 words)

 GCÐMS Identification of Sympathomimetic Amine Drugs in Urine: Rapid Methodology Applicable for   (Site not responding. Last check: 2007-10-22)
A method was developed that permitted rapid identification in urine of the following sympathomimetic amines: amphetamine, benzphetamine, cathinone, desmethylsegiline, diethylpropion, ephedrine, fenfluramine, mazindol, methylenedioxyamphetamine, methylenedioxyethylamphetamine, methylenedioxymethamphetamine, mescaline, methamphetamine, methcathinone, methylaminorex, methylphenidate, pemoline, phendimetrazine, phenylepherine, phentermine, phenylpropanolamine, pseudoephedrine, and selegiline.
Those sympathomimetic amines containing a primary or secondary amine, a hydrazine, and/or hydroxyl (except mazindol) functional groups were derivatized effectively using an on-column derivatization technique that used a reagent consisting of 10% fluoroanhydride in hexane, whereas the other sympathomimetic amines, including mazindol, were analyzed underivatized.
Fragmentation ion abundance was maximized at an injection-port temperature of 260°C, and this enhanced sensitivity coupled with the better chromatographic resolution of the individual sympathomimetic amines prompted the selection of HFBA as the derivatizing agent of choice.
www.jatox.com /abstracts/2000/april/211-valentine.html   (451 words)

 RESP 315
Sympathomimetic bronchodilator drugs bind with the adrenergic Beta-2 receptors just like norepinephrine would normally do.
Subcutaneous injection of sympathomimetic drugs is important in the management of acute bronchoconstriction.
Contraindications: Hypersensitivity to sympathomimetic amines, narrow-angle glaucoma, hemorrhage, traumatic or cardiogenic shock, cardiac dilation, cerebral arteriosclerosis, coronary insufficiency, arrhythmias, organic heart of brain disease, during second stage of labor, for local anesthetic of fingers, toes, ears, nose, and genitalia.
www.dmacc.cc.ia.us /instructors/kegeorge/Pharmacology/notesUnit6.htm   (4228 words)

 Meridia (sibutramine) Pharmacology – not an SNRI   (Site not responding. Last check: 2007-10-22)
The classic effects of a sympathomimetic are increase in cardiac output and vasoconstriction which together cause an increase in blood pressure.
The term sympathomimetic carries connotations that alert physicians to a spectrum of safety issues including abuse potential, insomnia, and cardiovascular actions.
This has significant implications for the safety of SIBUT and potential long-term changes in sympathetic tone with regional specificity, the sort of phenomenon that may underlie primary pulmonary hypertension and irregular perfusion of the heart by carotid arteries.
www.drugintel.com /drugs/documents/meridia_sibutramine_pharmacology.htm   (2578 words)

 [No title]
In order for "indirect" acting amines such as tyramine to exert their effects, they must first be taken up by the monoamine reuptake system and then release norepinephrine from storage granules.
These agents produce a physiologic response that is similar to the response produced by exogenous norepinephrine ("sympathomimetic").
Tyramine is an indirect sympathomimetic which works by releasing endogenous catecholamines from nerve endings.
www.kumc.edu /research/medicine/pharmacology/CAI/webCAI/blk1/adrergs.wbc   (2445 words)

 Ionamin--Buy Ionamin--Order Ionamin online--Purchase Ionamin, where to buy Ionamin   (Site not responding. Last check: 2007-10-22)
Sympathomimetic appetite Suppressants (Ionamin) are used in the short-term treatment of obesity.
Because of this, these medicines are useful only during the first few weeks of a weight-loss program.
Changes in eating habits and activity level must be developed and continued long-term in order for you to continue losing weight and to keep the lost weight from returning.
www.ionamin.48xu.com   (2249 words)

 Herbal Energizers: Speed By Any Other Name   (Site not responding. Last check: 2007-10-22)
All of these stimulants belong in the class sympathomimetic amines, a potentially dangerous and addictive class of drugs similar in structure and actions to amphetamines.
Sympathomimetic amines are a class of drugs that imitate the actions of the sympathetic nervous system (Crimson and Jermain, 1993, Knoben and Anderson, 1988).
Most side effects and risks of sympathomimetic amines are tied to abnormally high or chronic stimulation of the sympathetic nervous system.
www.cwu.edu /~jenkinsa/speed.html   (2955 words)

 [No title]
The answer is C. The sympathomimetic agents produce vasoconstriction in the smooth muscle, in blood vessels supplying skin and mucous membranes, also on salivary and certain sweat glands (alpha-1).
The answer is B. The SYMPATHOMIMETIC effect on the heart (beta-1) is an increase in both rate and force of contraction.
Many sympathomimetic agents stimulate alpha receptors as well as beta receptors rising the possibilities of further modification of the apparent responses.
www.kumc.edu /research/medicine/pharmacology/CAI/webCAI/blk1/as04.wbc   (1858 words)

 Ionamin Drug Information
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or amphetamine, dextroamphetamine, ephedrine, epinephrine, isoproterenol, metaproterenol, methamphetamine, norepinephrine, phenylephrine, phenylpropanolamine, pseudoephedrine, terbutaline, or other appetite suppressants.
If a pregnant woman takes this medicine in high doses or more often than the doctor has directed, it may cause withdrawal symptoms in the newborn baby.
Studies on these medicines have been done only in adult patients, and there is no specific information comparing use of sympathomimetic appetite suppressants in children with use in other age groups.
www.drugs.com /cons/Ionamin.html   (2356 words)

Data for other combinations of SSRI and sympathomimetic agent are not available.
Additionally, some sympathomimetic agents like fenfluramine and dexfenfluramine (no longer commercially marketed) may possess serotonergic activity and should generally not be administered with SSRIs because of the additive risk of serotonin syndrome, which is a rare but serious and potentially fatal condition thought to result from hyperstimulation of brainstem 5HT1A receptors.
Patients should also be > monitored for serotonergic effects and > advised to report any symptoms such as CNS > irritability, altered consciousness, > confusion, myoclonus, ataxia, abdominal > cramping, hyperpyrexia, shivering, pupillary > dilation, diaphoresis, hypertension, and > tachycardia" > hope that helps-plz check w/urdr.
www.rxlist.com /rxboard/prozac.pl?read=871   (433 words)

 SFM June 2001: Those OTC Diet Meds
Those preparations based on sympathomimetic agents are finally becoming a source of concern to the Food and Drug Administration (FDA), as well as a source of attraction for plaintiff's attorneys.
As far as sympathomimetic amines are concerned, we have less difficulty than do our European colleagues.
The marketers of these potentially dangerous preparations have come up with an interesting gimmick: they are including precursors of sympathomimetic amines in the formulation of these very complicated preparations.
www.sfms.org /sfm/sfm601e.htm   (534 words)

 Ephedra sinica
Ephedrine, a sympathomimetic drug that has a high potential for abuse and can be readily obtained without a prescription in unrestricted quantities, has rarely been associated with stroke.
Abstract: Ever since the introduction of the alkaloid ephedrine as an anti- asthmatic, the CNS stimulatory effects of this sympathomimetic have been a problem in therapy.
Abstract: The purpose of this study was to evaluate heart rate and blood pressure responses to a commercially available source of ma-haung, a natural source of the sympathomimetic substance, ephedrine, and to evaluate the pharmacokinetic properties of the product in normotensive, healthy adults.
www.home.caregroup.org /clinical/altmed/interactions/Herbs/Ephedra_sinica.htm   (5072 words)

 Bill Summary H. F. 478
Precludes school administrators from obligating a parent in a readmission plan to provide sympathomimetic medication to the parent's child as a condition of the child being readmitted to school after being suspended.
Indicates that a parent's refusal to provide the parent's child with sympathomimetic medications is not part of the definition of educational neglect under the law governing maltreatment of minors.
Encourages the contractor to examine the number of children who take sympathomimetic medications at home and not at school, the previous interventions tried with children taking sympathomimetic medications, the types of practitioners who prescribe sympathomimetic medications and what pressures families have experienced in terms of providing their children with sympathomimetic medications.
ww3.house.leg.state.mn.us /scripts/billsum.pl?fname=hr478&session=82   (434 words)

 [No title]
AN ACT RELATING TO SYMPATHOMIMETIC MEDICATIONS FOR STUDENTS It is hereby enacted by the General Assembly of the State of Vermont: Sec.
FINDINGS The general assembly finds that: (1) The Federal Drug Administration has analyzed per capita use of methylphenidate, which is manufactured under the brand name Ritalin, in each state, and found that Vermont has the second highest consumption of the drug.
A medical inspector or a teacher may recommend that a child be evaluated by an appropriate medical practitioner; however, a parent or guardian may agree or disagree to allow the child to take sympathomimetic medication.
www.leg.state.vt.us /docs/2002/bills/intro/s-287.doc   (358 words)

 Appetite Suppressants, Sympathomimetic (Systemic)
The sympathomimetic appetite suppressants can help you to lose weight while you are learning new ways to eat and to exercise.
Pregnancy—If a pregnant woman takes this medicine in high doses or more often than the doctor has directed, it may cause withdrawal symptoms in the newborn baby.
Children—Studies on these medicines have been done only in adult patients, and there is no specific information comparing use of sympathomimetic appetite suppressants in children with use in other age groups.
www.healthyweightforum.org /eng/weight_loss_medication/appetite-suppressants.asp   (2194 words)

 NGC - NGC Summary
For intracavernous injection of a sympathomimetic agent, the Panel recommends use of phenylephrine because this agent minimizes the risk of cardiovascular side effects that are more common for other sympathomimetic medications.
During and following intracavernous injection of sympathomimetic drugs, the physician should observe patients for subjective symptoms and objective findings consistent with known undesirable effects of these agents: acute hypertension, headache, reflex bradycardia, tachycardia, palpitations, and cardiac arrhythmia.
Aspiration with or without injection of sympathomimetic agents is not recommended as treatment.
www.guideline.gov /summary/summary.aspx?doc_id=3741   (911 words)

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