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	MedFriendly.com: Syringomyelia
		Syringomyelia is a rare condition in which long, fluid filled spaces are present in the central gray matter (a gray looking substance) of the spinal cord and surrounded by thick tissues made of glial cells.
		About 70% of syringomyelia cases are due to abnormalities in the back of the brain, such as Chiari malformation Chiari's malformation is a condition in which important parts of the back, bottom part of the brain extends downwards through the bottom of the skull where the brain joins the spinal cord.
		The signs and symptoms of syringomyelia are numerous and will differ depending on the size of the fluid-filled spaces and where they are located.
	www.medfriendly.com /syringomyelia.html (1202 words)

	The Cavalier King Charles Spaniel Club - Inheritance of Syringomyelia
		Syringomyelia is a condition whereby fluid filled cavities develop within the spinal cord.
		Syringomyelia is a consequence of an obstruction to cerebrospinal fluid (CSF) flow.
		A small syringomyelia may also be found as an incidental finding, with no recognised clinical signs, in the investigation of another neurological disease.
	www.thecavalierclub.co.uk /health/syringo/syringom.html (1316 words)

	MedlinePlus Medical Encyclopedia: Syringomyelia
		Syringomyelia is damage to the spinal cord, caused by a formation of a fluid-filled cavity within the cord.
		Syringomyelia is caused by a formation of a fluid-filled cavity within the spinal cord.
		A spinal CT with myelogram or an MRI of the spine confirms syringomyelia and determines the exact location and extent.
	www.nlm.nih.gov /medlineplus/ency/article/001398.htm (475 words)

	Syringomyelia (SM) and the Cavalier King Charles Spaniel
		Syringomyelia (SM -- also known as syrinx and hydromyelia, and occasionally mis-identified as Arnold Chiari malformation) is an intraspinal disorder due to the congenital malformation referred to as caudal occipital malformation syndrome (COMS) or syringomyelia secondary to occiptial hypoplasia (Chiari-like malformation).
		Syringomyelia results when the cerebrospinal fluid is prevented from circulating normally and is forced into the spinal cord, creating a cavity called a syrinx.
		Technically, syringomyelia is the cavitation of the spinal cord parenchyma, and hydromyelia is a dilatation of the central canal within the spinal cord.
	www.cavalierhealth.org /syringomyelia.htm (3735 words)

	Syringomyelia
		Syringomyelia is the formation of a fluid-filled cyst (syrinx) within the spinal cord.
		The symptoms of syringomyelia vary from one individual to the next, depending on the severity and location of the cyst.
		In some cases of syringomyelia, the cyst grows into the brain stem and interferes with vital functions such as breathing and heartbeat.
	www.betterhealth.vic.gov.au /bhcv2/bhcarticles.nsf/pages/Syringomyelia?open (735 words)

	Syringomyelia
		Syringomyelia (sear-IN-go-my-EEL-ya) is a disorder in which a cyst forms within the spinal cord.
		The main goal of surgery is to provide more space for the cerebellum (Chiari malformation) at the base of the skull and upper neck, without entering the brain or spinal cord.
		Scientists across the country continue to explore the mechanisms that lead to the formation of syrinxes in the spinal cord.
	healthlink.mcw.edu /article/923779378.html (1509 words)

	Syringomyelia
		Syringomyelia is a neurological disorder characterized by a fluid-filled cavity (syrinx) within the spinal cord.
		Individuals with Syringomyelia in the upper (cervical and thoracic) part of the spinal cord may first notice loss of feeling for pain and temperature in their fingers, hands, arms, and upper chest.
		Syringomyelia is most often a congenital disorder associated with abnormalities of the hind brain.
	hw.healthdialog.com /kbase/nord/nord381.htm (1501 words)

	Clinical Study: 92-N-0226, Establishing the Physiology of Syringomyelia (Site not responding. Last check: 2007-10-13)
		Syringomyelia is a pocket within the CSF channels that results from abnormal CSF flow.
		Patients with syringomyelia may be unable to detect sensations of pain and heat.
		Prior surgery for syringomyelia does not result in exclusion from the study if there is radiographic evidence of a syrinx and there is evidence of neurological deterioration related to the syrinx.
	clinicalstudies.info.nih.gov /cgi/wais/bold032001.pl?A_92-N-0226.html@chiari (413 words)

	Syringomyelia Fact Sheet: National Institute of Neurological Disorders and Stroke (NINDS)
		Because syringomyelia can occur in association with other conditions, estimates of the number of Americans with the disorder vary widely, but a conservative estimate is that about 40,000 people in the
		If not treated surgically, syringomyelia often leads to progressive weakness in the arms and legs, loss of hand sensation, loss of bladder and other functions, and chronic, severe pain.
		It is also considered important to remove scar tissue attached to the membranes that “tether” the cord in place and prevent the free flow of CSF around it.
	www.ninds.nih.gov /disorders/syringomyelia/detail_syringomyelia.htm (2095 words)

	Syringomyelia Information Page: National Institute of Neurological Disorders and Stroke (NINDS)
		Magnetic resonance imaging (MRI) has significantly increased the number of syringomyelia cases diagnosed in the beginning stages of the disorder.
		This malformation occurs during the development of the fetus and causes the lower part of the cerebellum to protrude from its normal location in the back of the head into the cervical or neck portion of the spinal canal.
		Syringomyelia may occur as a complication of trauma, meningitis, hemorrhage, a tumor, or arachnoiditis.
	www.ninds.nih.gov /disorders/syringomyelia/syringomyelia.htm (713 words)

	NIH Guide: SYRINGOMYELIA
		This PA, Syringomyelia, is related to the priority areas of chronic disabling conditions.
		Pathologically, syringomyelia is characterized by formation of a syrinx, or fluid-filled cyst, in the spinal cord, which expands and elongates over time.
		Although this abnormality is thought to be present at birth, the onset of syringomyelia does not occur until adulthood.
	grants.nih.gov /grants/guide/pa-files/PA-95-017.html (1668 words)

	Syringomyelia
		Apart from offering support for the distress that syringomyelia causes to owners and dogs alike, the group has provided a forum for debate and a means of disseminating information.
		Mild syringomyelia may also be found as an incidental finding, with no recognized clinical signs, in the investigation of another neurological disease.
		The syringomyelia can be easily visualized as a pocket of fluid within the spinal cord.
	cavalierhealthfoundation.com /syringomyelia.htm (2964 words)

	Clinical Study: 01-N-0085, Establishing the Pathophysiology of Primary Spinal Syringomyelia (Site not responding. Last check: 2007-10-13)
		Etiologies of primarily spinal syringomyelia include 1) intradural scarring which is post-traumatic, post-inflammatory, or post-operative, 2) intradural-extramedullary masses such as arachnoid cysts or meningiomas, and 3) extramedullary-extradural spinal lesions such as cervical spondylosis or spinal deformity.
		Presyringomyelia, a recently described state of spinal cord edema associated with progressive myelopathy and obstruction in CSF flow, is a precursor stage to syringomyelia that is consistent with this hypothesis.
		Have syringomyelia or "presyringomyelia" (swelling of the spinal cord that precedes syringomyelia), documented by MRI.
	clinicalstudies.info.nih.gov /cgi/wais/bold032001.pl?A_01-N-0085.html@chiari (457 words)

	Complete Spontaneous Resolution of Childhood Chiari I Malformation and Associated Syringomyelia -- Sun et al. 107 (1): ...
		The diagnosis of Chiari I malformation and associated syringomyelia is often made in childhood.
		Aboulezz A, Sartor K, Geyer C, Gado M Position of cerebellar tonsils in the normal population and in patients with Chiari malformation: a quantitative approach with MR imaging.
		Oldfield E, Muraszko K, Shawker T, Patronas N Pathophysiology of syringomyelia associated with Chiari I malformation of the cerebellar tonsils.
	pediatrics.aappublications.org /cgi/content/full/107/1/182 (1845 words)

	eMedicine - Syringomyelia : Article by Ayman Ali Galhom, MD, PhD (Site not responding. Last check: 2007-10-13)
		Background: Syringomyelia is the development of a fluid-filled cavity or syrinx within the spinal cord.
		This theory proposes that syringomyelia results from a “water hammer”-like transmission of pulsatile CSF pressure via a communication between the fourth ventricle and the central canal of the spinal cord through the obex.
		Lumbar syringomyelia can occur and is characterized by atrophy of the proximal and distal leg muscles with dissociated sensory loss in the lumbar and sacral dermatomes.
	www.emedicine.com /neuro/topic359.htm (3721 words)

	Canine Syringomyelia
		Cavaliers with syringomyelia usually have their first signs between 6 months and 3 years of age; however, dogs of any age may be presented.
		Syringomyelia is a devastating disease in both dogs and humans.
		Rusbridge C and Knowler SP, 2003 Hereditary aspects of occipital bone hypoplasia and syringomyelia (Chiari type I malformation) in cavalier King Charles spaniels.
	www.asap.org /2005/canine-syringomyelia.html (896 words)

	Syringomyelia Breeding Protocol In Cavalier King Charles Spaniel
		Knowler have been conducting an extensive study of syringomyelia and the Cavalier King Charles Spaniel for several years, and they published their first recommended breeding guidelines for SM in January 2004.
		The diagnosis of syringomyelia is easily confirmed by magnetic resonance imaging (MRI), but neurologists have yet to define what is meant by the term “clear”, given that most Cavaliers have a degree of skull malformation.
		The aim of these recommendations is to reduce the incidence of symptomatic syringomyelia in the breed -- not to create litters of puppies guaranteed not to have SM -- as the chance of producing an affected dog cannot be predicted without knowing the inheritance.
	www.cavalierhealth.org /smprotocol.htm (2173 words)

	Cavalier King Charles Spaniel Club - USA - Syringomyelia, A research update (Site not responding. Last check: 2007-10-13)
		Unfortunately syringomyelia is very widespread in CKCS lines and the number of potential carriers is huge so that breeding program based on avoiding certain dogs is not feasible or advisable as this will further narrow an already small gene pool resulting an increased likelihood of other inherited diseases.
		Dogs that carry syringomyelia or heart disease will have “good genes” for other inherited factors and we do not want to lose this valuable genetic material.
		A blood test for the gene(s) would be ideal because it allows carriers or even affected dogs to breed with non carriers (who may carry the tendency for a different disease).
	www.ckcsc.org /CKCSC/CKCSC_INC.NSF/FOUNDED-1954/SYRINGOMYELIA.HTML (1340 words)

	Syringomyelia Facts
		Syringomyelia (SM) is a disorder in which a cyst forms within the spinal cord.
		A syrinx may then develop in the cervical region of the spinal cord; this is referred to as communicating syringomyelia.
		This is a question often asked by individuals and family members of someone with CMI and/or syringomyelia.
	www.syringo.org (840 words)

	Motor neurone disease Health Guide - Health Guides Online
		Another example of damage to cell bodies of motor neurones is syringomyelia where cavities form in the brainstem and spinal cord, lying near to the center of the cord.
		This is due to the trapping of cerebrospinal fluid (CSF) in the ventricles of the brain because it cannot be drained.
		With a condition called "syringomyelia", if the lesions that have caused the blockage to the fluid filled spaces of the brain (the ventricles) are demonstrated early, surgical treatment may be possible.
	www.healthguidesonline.com /Motor_neurone_disease.html (2087 words)

	Syringomyelia - history
		Syringomyelia is derived from the Greek words, syrinx (meaning tube or pipe) and muelos (meaning marrow).
		In 1824, Charles Ollivier d'Angers provided the very descriptive name "syringomyelia" to the cylindrical dilatation of the spinal cord, which in his illustrative case report, communicated with the fourth ventricle.
		This was the first recorded surgical procedure to treat syringomyelia.
	depts.washington.edu /neurosur/chiari/s_history.htm (132 words)

	Clinical Trial: Study and Surgical Treatment of Syringomyelia
		Objective: The goal of this study is to establish the mechanism(s) of progression of primarily spinal syringomyelia (PSS), the type of syringomyelia that is associated with pathology in the spinal column and not at the craniocervical junction.
		Study Population: Subjects will have primary spinal syringomyelia associated with 1) intradural scarring which is post-traumatic, post-inflammatory, or post-operative, 2) intradural-extramedullary masses such as arachnoid cysts or meningiomas, and 3) extramedullary-extradural spinal lesions such as cervical spondylosis or spinal deformity, or 4) an intramedullary tumor.
		Pathophysiology of syringomyelia associated with Chiari I malformation of the cerebellar tonsils.
	www.clinicaltrials.gov /ct/show/NCT00011245 (738 words)

	Herbal Medciine for Syringomyelia (Site not responding. Last check: 2007-10-13)
		Syringomyelia is a rare condition in which long, fluid filled spaces are present in the central gray matter of the spinal cord.
		One way to think of syringomyelia is if you were to take a hot dog and inject water into the center.
		This forms an abnormal cavity within the structure of the spinal cord, causes pressure and disrupts the normal function of the nerves that travel from that area of the cord.
	www.damo-qigong.net /treat/myelophathy/syringomyelia.htm (1320 words)

	Hypothesis on the pathophysiology of syringomyelia based on simulation of cerebrospinal fluid dynamics -- Chang and ...
		Surgical indication and results of foramen magnum decompression versus syringosubarachnoid shunting for syringomyelia associated with Chiari I malformation.
		Foramen magnum decompression with removal of the outer layer of the dura as treatment for syringomyelia occurring with Chiari I malformation.
		Pathological basis of spinal cord cavitation in syringomyelia: analysis of 105 autopsy cases.
	jnnp.bmjjournals.com /cgi/content/full/74/3/344 (2282 words)

	Chiari Malformations and Syringomyelia
		Syringomyelia is a condition characterized by a syrinx (fluid-filled cyst) in the spinal cord.
		In some instances, syringomyelia is caused by an injury.
		The Center for Human Genetics, in collaboration with Dr. Thomas Milhorat and colleagues of North Shore University Hospital/Manhasset NY and the American Syringomyelia Alliance Project, is investigating the hereditary basis of Chiari type I malformations with or without syringomyelia.
	www.chg.duke.edu /diseases/chiari.html (967 words)

	Focal (segmental) dyshidrosis in syringomyelia -- Sudo et al. 67 (1): 106 -- Journal of Neurology, Neurosurgery, and ...
		Syringomyelia is responsible for dyshidrosis as well as other disorders of the autonomic nervous system.
		Sudou K, Tashiro K. Segmental hyperhidrosis in syringomyelia with Chiari malformation.
		Chemical mediators of spinal inhibition of rat sympathetic neurones on stimulation in the nucleus tractus solitarii.
	jnnp.bmjjournals.com /cgi/content/full/67/1/106 (1634 words)

	Syringomyelia - Wheeless' Textbook of Orthopaedics
		- syringomyelia is a condition in which tubular cavity, or syrinx, in central area of spinal cord gradually expands leading to progressive myelopathy;
		Management of scoliosis due to syringomyelia in childhood and adolescence.
		Progressive scoliosis as the first presenting sign of syringomyelia: Report of a case.
	www.wheelessonline.com /ortho/syringomyelia (570 words)

	American Syringomyelia Alliance Project Inc, To improve the lives of persons affected by syringomyelia, Chiari ... (Site not responding. Last check: 2007-10-13)
		American Syringomyelia Alliance Project Inc, To improve the lives of persons affected by syringomyelia, Chiari malformation and related disorders while we find the cure.
		Syringomyelia is a chronic disorder involving the spinal cord.
		Living with Chiari (CM) and syringomyelia (SM) is a tough problem.
	www.asap4sm.com (198 words)

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