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Topic: TATA Binding Protein

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	TFIID (Site not responding. Last check: 2007-10-08)
		TFIID consists of a DNA binding subunit that recognizes the TATA element and is therefore designated TATA-binding protein (or TBP), as well as several TBP-associated factors (or TAFs).
		TBP is also a component of the RNA polymerase I and RNA polymerase III transcription complexes.
		The coordinates for the yeast TBP cocrystal with DNA by Sigler group.
	tfiib.med.harvard.edu /transcription/tfiid.html (327 words)

	Evidence for Functional Binding and Stable Sliding of the TATA Binding Protein on Nonspecific DNA -- Coleman and Pugh ...
		TATA crystal structure indicates that monomeric TBP binds TATA primarily through hydrophobic and van der Waals' interactions with the bases and sugars (14, 15, 16).
		TBP is known to be exquisitely temperature sensitive in its binding to TATA.
		The TBP dimer interface is proposed to overlap the concave DNA binding surface of TBP as envisioned in the dimeric crystal structure of the apo form of TBP (34, 35).
	www.jbc.org /cgi/content/full/270/23/13850 (8235 words)

	TATA binding protein TBP antibody [1TB18] (ab12089) datasheet (Site not responding. Last check: 2007-10-08)
		The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals.
		TFIID is composed of the TATA-binding protein TBP and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs.
		This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription.
	www.abcam.com /?datasheet=12089 (495 words)

	TATA binding protein. (Site not responding. Last check: 2007-10-08)
		We are performing single-molecule experiments to study the interaction of yeast TATA Binding Protein (TBP) with short pieces of surface-attached DNA.
		The binding of TBP to DNA is the first step in the initiation of gene transcription in eucaryotes by RNA polymerase II.
		The tata binding protein specifically recognizes and binds to promotor DNA containing the consensus sequence TATA(a/t)A(a/t)N (where N=A, T, C, or G).
	www.nbi.dk /~tweezer/tatabp.htm (148 words)

	tutorial text
		The human TATA box-Binding Protein (hTBP) is a requisite protein in the assembly of a functional transcription preinitiation complex (PIC) for RNA polymerase II (Pol II).
		Unlike most DNA binding proteins, which recognize a pattern of H-bonds from amino acid side chains to Nitrogen and Oxygen atoms in the major groove of DNA and do not alter the DNA helix, hTBPc binds to the minor groove with mostly non-polar and hydrophobic interactions (Juo et al., 1996).
		TATA boxes are also used, as opposed to pure A- homopolymer runs, because of the structural rigidity of A-tracts.
	srv2.lycoming.edu /~newman/courses/bio43701/tatabp/right.htm (1959 words)

	Adeno-Associated Virus Major Rep78 Protein Disrupts Binding of TATA-Binding Protein to the p97 Promoter of Human ...
		Lanes 1 and 3, GST-Rep78 and GST proteins eluted with 10 mM glutathione (reduced form); lanes 2 and 4, GST-Rep78 and GST protein conjugated on glutathione-Sepharose 4B beads.
		GST-Rep78 inhibits TBP binding to DNA in the presence of Sp1.
		The AAV origin binding protein Rep68 is an ATP-dependent site-specific endonuclease with DNA helicase activity.
	jvi.asm.org /cgi/content/full/74/5/2459 (3990 words)

	BIO 317 - Tim Issac - TATA Box Binding Protein (Site not responding. Last check: 2007-10-08)
		The TATA box-binding protein (TBP) is necessary for the 3 various RNA polymerases to initiate transcription.
		The protein's approximate twofold intramolecular symmetry resembles a saddle-shaped structure with anti-parallel beta-sheet.
		The TBP is the green area and the TATA box consensus sequence is depicted in the red and yellow region.
	www.creighton.edu /~tissac/rasmol.html (398 words)

	Multiple Functions of the Nonconserved N-Terminal Domain of Yeast TATA-Binding Protein -- Lee and Struhl 158 (1): 87 -- ...
		Sequential truncation of the N terminus of TBP.
		Viability of TBP derivatives with successive deletions of the N-terminal domain was assessed by growth on medium containing 5-fluoroorotic acid (FOA) in a plasmid shuffle assay.
		The association of TBP with the TATA element is a crucial regulatory
	www.genetics.org /cgi/content/full/158/1/87 (3845 words)

	Binding of TATA Binding Protein to a Naturally Positioned Nucleosome Is Facilitated by Histone Acetylation -- Sewack et ...
		Binding of TATA Binding Protein to a Naturally Positioned Nucleosome Is Facilitated by Histone Acetylation -- Sewack et al.
		Binding of TATA Binding Protein to a Naturally Positioned Nucleosome Is Facilitated by Histone Acetylation
		the binding of TBP was assayed in vitro using an in vivo-assembled
	mcb.asm.org /cgi/content/abstract/21/4/1404 (659 words)

	The TATA-Binding Protein (TBP) from the Human Fungal Pathogen Candida albicans Can Complement Defects in Human and ... (Site not responding. Last check: 2007-10-08)
		TBP is known to interact with 8 bp of DNA (24),
		Isolation of the gene encoding the yeast TATA binding protein TFIID: a gene identical to the SPT15 suppressor of Ty element insertions.
		Definition of multiple, functionally distinct TATA elements, one of which is a target in the hsp70 promoter for E1A regulation.
	jb.asm.org /cgi/content/full/180/7/1771 (2814 words)

	Selective Binding of the TATA Box-Binding Protein to the TATA Box-Containing Promoter: Analysis of Structural and ... (Site not responding. Last check: 2007-10-08)
		Transcription by RNA polymerase II is initiated by the binding of the transcription factor (TF) IID to the consensus sequence
		TBP binds the transcriptionally inactive TA sequence but the resulting complex is not efficiently recognized by TFIIB and TFIIA.
		DNA bending is an important component of site-specific recognition by the TATA binding protein.
	www.biophysj.org /cgi/content/full/75/5/2411 (5305 words)

	Ikura Lab Research Projects and Selected Publications
		Protein S is a development-specific calcium-binding protein which is implicated in the cell-cell interaction process in this bacterium.
		In 1998, we determined the solution structure of TATA binding protein (TBP) in complex with the N-terminal suppressor domain of TBP-associated factor 230 or TAF230 (1TBA), which revealed an elegant mechanism for autoinhibition involving molecular mimicry of the partially unwound structure of a TBP-bound TATA element (Liu et al.
		The EF-hand protein superfamily is a good example of this: all proteins in the superfamily contain the simple helix-loop-helix motif which is responsible for Ca binding, yet perform diverse biological functions.
	nmr.uhnres.utoronto.ca /ikura/projects.html (1890 words)

	A Human TATA Binding Protein-Related Protein with Altered DNA Binding Specificity Inhibits Transcription from Multiple ...
		TBP and is expressed in most human tissue.
		Chong, J. A., Moran, M. M., Teichmann, M., Kaczmarek, J. S., Roeder, R., Clapham, D. TATA-Binding Protein (TBP)-Like Factor (TLF) Is a Functional Regulator of Transcription: Reciprocal Regulation of the Neurofibromatosis Type 1 and c-fos Genes by TLF/TRF2 and TBP.
		Guillebault, D., Sasorith, S., Derelle, E., Wurtz, J.-M., Lozano, J.-C., Bingham, S., Tora, L., Moreau, H. A New Class of Transcription Initiation Factors, Intermediate between TATA Box-binding Proteins (TBPs) and TBP-like Factors (TLFs), Is Present in the Marine Unicellular Organism, the Dinoflagellate Crypthecodinium cohnii.
	mcb.asm.org /cgi/content/abstract/19/11/7610 (763 words)

	Differential expression and interaction of transcription co-activator MBF1 with TATA-binding protein (TBP) in the ... (Site not responding. Last check: 2007-10-08)
		Bellorini, M., Moncollin, V., D'Incalci, M., Mongelli, N. and Mantovani, R. Distamycin A and tallimustine inhibit TBP binding and basal in vitro transcription.
		Bondareva, A. and Schmidt, E. Early vertebrate evolution of the TATA-binding protein, TBP.
		Fast, N. M., Logsdon, J. M., Jr and Doolittle, W. Phylogenetic analysis of the TATA box binding protein (TBP) gene from Nosema locustae: evidence for a microsporidia-fungi relationship and spliceosomal intron loss.
	mic.sgmjournals.org /cgi/content/full/150/5/1207 (3433 words)

	The TATA Element and Its Context Affect the Cooperative Interaction of TATA-binding Protein with the TFIIB-related ... (Site not responding. Last check: 2007-10-08)
		The TATA Element and Its Context Affect the Cooperative Interaction of TATA-binding Protein with the TFIIB-related Factor, TFIIIB70 -- Librizzi et al.
		The TATA Element and Its Context Affect the Cooperative Interaction of TATA-binding Protein with the TFIIB-related Factor, TFIIIB
		In contrast, the nonconsensus and yU6 TATAs increased the
	www.jbc.org /cgi/content/abstract/273/8/4563 (584 words)

	TATA box-binding protein (TBP)-related factor 2 (TRF2), a third member of the TBP family -- Rabenstein et al. 96 (9): ...
		TATA box-binding protein (TBP)-related factor 2 (TRF2), a third member of the TBP family -- Rabenstein et al.
		TATA box-binding protein (TBP)-related factor 2 (TRF2), a third member of the TBP family
		The TATA box-binding protein (TBP) is an essential component of the RNA polymerase II transcription apparatus in eukaryotic
	www.pnas.org /cgi/content/abstract/96/9/4791 (1243 words)

	TATA-binding protein promotes the selective formation of UV-induced (6-4)-photoproducts and modulates DNA repair in the ... (Site not responding. Last check: 2007-10-08)
		TBP is an essential factor for transcription initiation by all three nuclear RNA polymerases and plays a key role in assembly
		TBP binds to the SNR6 and GAL10 TATA elements as indicated in
		Kim, J.L., Nikolov, D.B. and Burley, S.K. (1993a) Co-crystal structure of TBP recognizing the minor groove of a TATA element.
	embojournal.npgjournals.com /cgi/content/full/18/2/433 (7595 words)

	CAG repeat expansion in the TATA box-binding protein gene causes autosomal dominant cerebellar ataxia -- Fujigasaki et ...
		CAG repeat expansion in the TATA box-binding protein gene causes autosomal dominant cerebellar ataxia -- Fujigasaki et al.
		The signal intensity of the 40 kDa band which corresponds to the expanded protein was stronger than that of the 37 kDa band.
		Recruitment of nonexpanded polyglutamine proteins in intranuclear aggregates in neuronal intranuclear hyaline inclusion disease.
	brain.oxfordjournals.org /cgi/content/full/124/10/1939 (3627 words)

	PDB Molecule of the Month: TATA-Binding Protein (Site not responding. Last check: 2007-10-08)
		The sigma subunit binds to these DNA sequences, assists the start of transcription, and then detaches from the polymerase as it continues transcription through the gene.
		When the first structures of TATA-binding protein were determined, researchers discovered that TATA-binding protein is not gentle when it binds to DNA.
		Instead, it grabs the TATA sequence and bends it sharply, as seen in PDB entries 1ytb, 1tgh and 1cdw.
	www.rcsb.org /pdb/molecules/pdb67_1.html (303 words)

	Casein kinase II regulation of yeast TFIIIB is mediated by the TATA-binding protein -- Ghavidel and Schultz 11 (21): ...
		Casein kinase II regulation of yeast TFIIIB is mediated by the TATA-binding protein
		protein (TBP), is a preferred substrate of CKII in vitro.
		TBP is the target of a CKII-mediated regulatory mechanism that
	www.genesdev.org /cgi/content/abstract/11/21/2780 (672 words)

	Nuclear Import of the TATA-binding Protein: Mediation by the Karyopherin Kap114p and a Possible Mechanism for ... (Site not responding. Last check: 2007-10-08)
		Nuclear Import of the TATA-binding Protein: Mediation by the Karyopherin Kap114p and a Possible Mechanism for Intranuclear Targeting -- Pemberton et al.
		Binding of the TATA-binding protein (TBP) to the promoter is the first and rate limiting step in the formation of transcriptional
		A role for nucleosome assembly protein 1 in the nuclear transport of histones H2A and H2B
	www.jcb.org /cgi/content/abstract/145/7/1407 (1328 words)

	WU Libraries Bio. Dept. 2002 Publications
		Expression, autoregulation, and DNA binding properties of the Mycobacterium tuberculosis TrcR response regulator.
		Three novel MYB proteins with one DNA binding repeat mediate sugar and hormone regulation of α-amylase gene expression.
		Rice TATA binding protein interacts functionally with transcription factor IIB and the RF2a bZIP transcriptional activator in an enhanced plant in vitro transcription system.
	www.library.wustl.edu /units/biology/reprints/2002.html (2252 words)

	protein data bank and other data related information (Site not responding. Last check: 2007-10-08)
		The Protein Data Bank (PDB) is operated by Rutgers, The State University of New Jersey and the San Diego Supercomputer Center at the University of California, San Diego -- two members of the Research...
		The Protein Data Bank (PDB) is operated by Rutgers, The State University of New Jersey and the San Diego Supercomputer Center at the University of California, San Diego -- two members of the...
		Kramer Green, J. Flippen-Anderson, J. Westbrook, H. Berman, and P. Bourne The RCSB Protein Data Bank: a redesigned query system and relational database based on the mmCIF schema Nucleic Acids...
	www.nethorde.com /data/protein-data-bank.html (329 words)

	Identification of a mouse TBP-like protein (TLP) distantly related to the drosophila TBP-related factor -- Ohbayashi et ...
		Identification of a mouse TBP-like protein (TLP) distantly related to the drosophila TBP-related factor -- Ohbayashi et al.
		Identification of a mouse TBP-like protein (TLP) distantly related to the drosophila TBP-related factor
		TATA-binding protein (TBP) is an essential factor for eukaryotic
	nar.oxfordjournals.org /cgi/content/abstract/27/3/750 (882 words)

	Protein Diet and Resources (Site not responding. Last check: 2007-10-08)
		Whether you are looking for your loved one or just looking for your own protein diet, you'll be sure to find exactly what you are looking for here.
		Many times, protein diet can be found at very low costs online.
		ProteinÂ° OS - The system from which we operateâ¢ Welcome to the ProteinÂ° OS, the system from which we operate.
	www.proteinbooth.com (458 words)

	Prof. Walter Schaffner
		MTs are small, cysteine-rich proteins that play important roles in metal homeostasis, metal detoxification and radical scavenging.
		Furthermore, in a collaborative effort with G. Multhaup (Berlin) we determine, in a Drosophila model, the contribution of Alzheimer precursor protein (APP) to copper homeostasis, and with the group of S. Hemmi we are studying aspects of viral cell type specificity.
		Pettersson, M. and Schaffner, W. A purine-rich DNA sequence motif present in SV40 and lymphotropic papovavirus binds a lymphoid-specific factor and contributes to enhancer activity in lymphoid cells.
	www.molbio.unizh.ch /groups/schaffner/index.shtml (5534 words)

	High-Mobility Group (HMG) Protein HMG-1 and TATA-Binding Protein-Associated Factor TAFII30 Affect Estrogen ... (Site not responding. Last check: 2007-10-08)
		bind to ERE in spite of high ligand-binding activity and electrophoretic
		Binding of Estrogen Receptor {beta} to Estrogen Response Element in Situ Is Independent of Estradiol and Impaired by Its Amino Terminus
		Functional interactions between a phage histone-like protein and a transcriptional factor in regulation of phi 29 early-late transcriptional switch
	mend.endojournals.org /cgi/content/abstract/11/8/1009 (961 words)

	Christopher C. Benz, MD, biosketch (Site not responding. Last check: 2007-10-08)
		Binding of an ETS-related protein within the DNase-I hypersensitivity site of the HER2/neu promoter in human breast cancer cells.
		Increased AP-1 DNA binding and Jun N-terminal kinase in human breast tumors with acquired tamoxifen resistance.
		Exon 4-encoded acidic domain in the epithelium-restricted Ets factor ESX confers potent transactivating capacity and binds to TATA-binding protein (TBP).
	cc.ucsf.edu /people/benz_christopher.html (971 words)

	A unified nomenclature for TATA box binding protein (TBP)-associated factors (TAFs) involved in RNA polymerase II ...
		A unified nomenclature for TATA box binding protein (TBP)-associated factors (TAFs) involved in RNA polymerase II transcription
		Dynlacht, B.D., Hoey, T., and Tjian, R. Isolation of coactivators associated with the TATA-binding protein that mediate transcriptional activation.
		Abundant Expression in Vascular Tissue of Plant TAF10, an Orthologous Gene for TATA Box-binding Protein-associated Factor 10, in Flaveria trinervia and Abnormal Morphology of Arabidopsis thaliana Transformants on its Overexpression
	www.genesdev.org /cgi/content/full/16/6/673 (2451 words)

	The DasSarma Lab Group (Site not responding. Last check: 2007-10-08)
		The vesicles are also bioengineerable, and their use in design of vaccines and for other applications is of current interest (6).
		The bop gene promoter, which is regulated by oxygen and light, responds to environmental changes, probably via the action of alternate TATA-binding protein and TFB proteins in this organism (7).
		The possibility of alternate DNA structures, such as Z-DNA, in the genome stabilized by high salinity is fascinating (8).
	zdna2.umbi.umd.edu /~dassarma/lab.html (405 words)

	Direct stimulation of transcription by negative cofactor 2 (NC2) through TATA-binding protein (TBP) -- Cang and Prelich ...
		Direct stimulation of transcription by negative cofactor 2 (NC2) through TATA-binding protein (TBP) -- Cang and Prelich 99 (20): 12727 -- Proceedings of the National Academy of Sciences
		the same surface of TBP that mediates the NC2 repression activity.
		Identification of a Novel TATA Element-binding Protein Binding Region at the N Terminus of the Saccharomyces cerevisiae TAF1 Protein
	www.pnas.org /cgi/content/abstract/99/20/12727 (455 words)

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