
	Where results make sense

Topic: TFMPP

Related Topics

BZP

Benzylpiperazine

Controlled Substances Act

MPTP

Catha edulis

Methamphetamine

Cocaine

GBL

GHB

Subcutaneous

Ted Neeley

	BZP and TFMPP Controlled Substances
		BZP and TFMPP are being encountered in several regions of the U.S. and their abuse has spread rapidly from the states where they were initially encountered.
		TFMPP is a serotonin releasing agent and binds to serotonin receptors in the brain.
		BZP and TFMPP will be subject to the regulatory controls and administrative, civil and criminal sanctions applicable to the manufacture, distribution, importing, exporting and possession of a Schedule I controlled substance.
	www.cognitiveliberty.org /dll/BZP_sched_intent.htm (0 words)

	5-HT1B Receptor-Mediated Presynaptic Inhibition of Retinal Input to the Suprachiasmatic Nucleus -- Pickard et al. 19 ...
		(0.9% saline) or the 5-HT receptor agonist TFMPP (25 mg/kg)
		The effect of TFMPP (a 5-HT receptor agonist) on the optic nerve-evoked EPSC was not blocked in the presence of the 5-HT and 5-HT receptor antagonists WAY-100635 and ritanserin, respectively.
		TFMPP on the optic nerve-evoked EPSC and on the glutamate-evoked inward current in several neurons is shown.
	www.jneurosci.org /cgi/content/full/19/10/4034 (7025 words)

	Does TFMPP ( Molly) plus BZP mimic MDMA ( Ecstasy )? (Site not responding. Last check: )
		In the present study, we compared the neurochemistry of MDMA, BZP, and TFMPP in rats.
		The effects of MDMA, BZP, and TFMPP on transporter-mediated efflux of [(3)H]5-HT and [(3)H]MPP(+) (DA transporter substrate) were determined in synaptosomes.
		The effects of drugs on extracellular levels of 5-HT and DA were examined using in vivo microdialysis in conscious rats.
	www.mdma.net /tfmpp/tfmpp-bzp.html (257 words)

	TFMPP Information - Herbal Highs
		3- Trifluoromethylphenylpiperazine Monohydrochloride (TFMPP) is a piperazine and a CNS stimulant.
		TFMPP is usually used in combination with BZP or other Piperazines.
		TFMPP has only mild effects when not combined with benzylpiperazine, and produces aversive effects in animals rather than self-administration, which explains the decision not to permanently make TFMPP an illicit drug.
	www.herbalhighs.com /info/Ing_TFMPP.aspx (0 words)

	Scheduling Actions 2002 - " Schedules of Controlled Substances: Temporary Placement of Benzylpiperazine and ...
		BZP and TFMPP are being encountered in several regions of the United States and their abuse has spread rapidly from the states where they were initially encountered.
		BZP and TFMPP are subject to Schedule I security requirements and must be manufactured, distributed and stored in accordance with § § 1301.7, 1301.72(a), (c), and (d), 1301.73, 1301.74, 1301.75(a) and (c) and 1301.76 of Title 21 of the Code of Federal Regulations.
		All labels and labeling for commercial containers of BZP and TFMPP which are distributed on or after October 21, 2002 shall comply with requirements of § § 1302.02-1302.07 of Title 21 of the Code of Federal Regulations.
	www.deadiversion.usdoj.gov /fed_regs/sched_actions/2002/fr09202.htm (1799 words)

	TFMPP : Legal Status - Herbal Highs
		TFMPP is NOT classed as a controlled substance in the UK and is legal to possess.
		TFMPP became a controlled substance on Feb 18th 2003 in Greece.
		TFMPP is NOT a controlled substance in New Zealand all though is restricted by the age of person buying.
	www.herbalhighs.com /info/tfmpp_legal_status.aspx (0 words)

	Erowid TFMPP Vault: Basics
		3-Trifluoromethylphenylpiperazine Monohydrochloride (TFMPP) is a piperazine and a CNS stimulant.
		TFMPP has been found in some samples of Ecstasy pills in the U.S. [ Main TFMPP Vault ]
		TFMPP is used orally at doses of between 25-100 mg, usually in combination with BZP or other piperazines.
	www.erowid.org /chemicals/tfmpp/tfmpp_basics.shtml (108 words)

	Scheduling Actions - 2002 "Schedules of Controlled Substances: Temporary Placement of Benzylpiperazine and ...
		The increasing abuse of BZP and TFMPP in the United States is evidenced by increasing encounters by law enforcement agencies.
		BZP and TFMPP, with their easy availability and their so-called legal status, are becoming drugs of abuse in the United States.
		As with amphetamine and MDMA, the effects of BZP are stimulant-like and those of TFMPP are hallucinogen-like.
	www.deadiversion.usdoj.gov /fed_regs/sched_actions/2002/fr07182.htm (1646 words)

	N-substituted piperazines abused by humans mimic the molecular mechanism of 3,4-methylenedioxymethamphetamine (MDMA, or ...
		The effects of MDMA, BZP, and TFMPP on transporter-mediated efflux of [H-3] 5-HT and [H-3] MPP+ (DA transporter substrate) were determined in synaptosomes.
		BZP released [H-3] MPP+, whereas TFMPP was a selective releaser of [H-3] 5-HT.
		Administration of BZP plus TFMPP at a 1: 1 ratio (BZP/TFMPP) produced parallel increases in dialysate 5- HT and DA; a 3 mg/kg dose of BZP/TFMPP mirrored the effects of MDMA.
	www.rti.org /abstract.cfm?pubid=4220 (339 words)

	From CRS: Appetite Suppressants (Site not responding. Last check: )
		TFMPP also consistently increased non-REM (NREM) sleep during the second hour after drug injection, though this effect was not dose-related (it was seen at all doses tested).
		TFMPP, but not fluoxetine, also increased at all doses the number of delta waves per minute of NREM sleep in the second hour.
		A structural analog of TFMPP that is inactive at serotonin (5-HT) receptors [4-(m-trifluoromethylphenyl)piperadine; LY97117] was also tested, and found to be devoid of effects on NREM and REM sleep.
	darkwing.uoregon.edu /~freinkel/cr/crspsgs/appet1.htm (1189 words)

	Molly
		Detroit, MI- Special Agents of the U.S. Drug Enforcement Administration (DEA) working with the Michigan State Police and local law enforcement agencies have recently discovered the presence of a new club drug that is being sold to high school and college age students at "Rave" parties throughout the Detroit and Ann Arbor areas.
		TFMPP and Benzylpiperazine (BZP) were both given emergency controlled substance scheduling by the U.S. Drug Enforcement Administration in September 2002.
		TFMPP was given Schedule I status, meaning it has a high potential for abuse and no accepted medical use.
	www.ner.cap.gov /ddr/molly.htm (446 words)

	Schedules of Controlled Substances: Placement of 2,5-Dimethoxy-4-(n)-propylthiophenethylamine, N-Benzylpiperazine and ... (Site not responding. Last check: )
		TFMPP is an industrial chemical and shares some pharmacological similarities with 3,4- methylenedioxymethamphetamine (MDMA or Ecstasy).
		TFMPP generalizes to MDMA's discriminative stimulus effects and serves as discriminative stimulus in rats.
		TFMPP, similar to MDMA, has been shown to release 5-HT from central serotonergic neurons through uptake carrier- dependent mechanism (Pettibone D and Williams M, Biochem.
	www.washingtonwatchdog.org /documents/fr/03/se/08/fr08se03-22.html (2716 words)

	Ajanacom: legal highs, piperazines, bzp, tfmpp, benzylpiperazine, trifluoromethylphenylpiperazine
		The psychoactive effect caused by a dose taken of TFMPP is sometimes described as being somewhere between empathogens such as MDMA and entheogens such as psilocybin, mescaline, or LSD.
		With closed eyes, psychoptic effects are found in most cases that involve partly colored visions and patterns similar to those caused by mescaline.
		However, what is considered "an active dose" of TFMPP can be highly variable and depends on the kind of effects desired.
	www.ajanacom.com /tfmpp.php?osCsid=76ece90252dd44846883d0422d482f00 (134 words)

	[No title]
		There are many people who lack the discrimination to tell the difference between a Lafite-Rothschild 1932 and a Gallo 1997, or perhaps a better analogy would be that they cannot discern the former from a Budweiser.
		At first blush, my opinion, purely my opinion, would be that TFMPP would have such a 'resemblance' to ecstasy.
		If in fact TFMPP is very similar, or extremely similar to ecstasy, then I would VERY MUCH like to know that from someone who has discriminating tastes.
	ecstasy.org /qanda/q50.html (314 words)

	[No title]
		The aim of our study was to identify their metabolites and to study their detectability with our systematic toxicological analysis (STA) procedure in urine.
		Methods: The drugs (BZP, TFMPP, mCPP, MDBP, MeOPP; 1 mg/kg body mass) were given to Wistar rats by gastric intubation and urine was collected over 24 hours.
		Results: The identified metabolites indicate that BZP, TFMPP, mCPP are hydroxylated at the aromatic ring, MeOPP is O-demethylated, and MDBP is demethylenated followed by methylation of one of the resulting hydroxy groups.
	www.tiaft.org /tiaft2001/lectures/l45_staack.doc (279 words)

	BZP TFMPP as well as mcpp meopp
		TFMPP was briefly emergency scheduled in Schedule I in the US, but the scheduling expired in April 2004 and has not been renewed.
		Because of its suspected activity on serotonin, a mixture of an equal amount of TFMPP and Benzylpiperazine is sometimes advertised as an ecstasy substitute.
		The SunRise party pack consists of 2g of Sunrise Pure BZP and 1 gram of Sunrise TFMPP.
	www.wackyherbs.com /html/bzp_tfmpp_etc.html (0 words)

	MDMA ( Ecstasy ), vs BZP and TFMPP
		The effects of MDMA, BZP, and TFMPP on transporter-mediated efflux of [3H]5-HT and [3H]MPP+ (DA transporter substrate) were determined in synaptosomes.
		The effects of drugs on extracellular levels of 5-HT and DA were examined using in vivo microdialysis in conscious rats.
		Administration of BZP plus TFMPP at a 1:1 ratio (BZP/TFMPP) produced parallel increases in dialysate 5-HT and DA; a 3 mg/kg dose of BZP/TFMPP mirrored the effects of MDMA.
	www.benzylpiperazine.com /mdma-substitute.html (0 words)

	University begins first studies into physical effects of party pills - The University of Auckland (Site not responding. Last check: )
		Researchers at The University of Auckland's School of Pharmacy have begun investigation into the effects that BZP and TFMPP have on the human body, the first in-depth controlled research into these chemicals and their effects.
		The use of BZP and TFMPP as recreational drugs is legal in many countries, including New Zealand.
		"The majority of the effects that BZP and TFMPP have on the human body are largely unknown" says Dr Bruce Russell, coordinator of the research.
	www.auckland.ac.nz /uoa/about/news/articles/2006/06/bzp.cfm (373 words)

	chemical_ban_10_11 (Site not responding. Last check: )
		BZP is found in combination with trifluoromethylphenylpiperazine (TFMPP) and produces an effect similar to methylenedioxymethamphetamine (MDMA) - or ecstasy.
		The use of BZP and TFMPP is comparatively new to WA and at the time of the raid, there were no controls over their possession or supply.
		Mr Kucera said the possession or supply of BZP and TFMPP would attract penalties as described by the Misuse of Drugs Act.
	www.ozbiker.org /news_current/chemical_ban_10_11.htm (251 words)

	BZP TFMPP as well as mcpp meopp
		3g of BZP Powder, 2g of TFMPP and 1g of BZP Granules, all for $100 NZ dollars (normal price $204) Each gram is packed separately.
		So many people asked us for TFMPP so we decided to get some in.
		These powders are not mixed so those who just prefer one or the other by itself do not need to worry.
	www.wackyherbs.com /html/bzp_tfmpp.html (0 words)

	Effects of 'Legal X' piperazine analogs on dopamine and serotonin release in rat brain - Publication - RTI International
		The ability of MDMA, BZP, and TFMPP to stimulate efflux of [H-3]5-11T and [H-3]MPP+ (a DA transporter substrate) was determined in vitro using release assays in synaptosomes.
		The ability of these drugs to increase extracellular 5-HT and DA in vivo was assessed using intracranial microdialysis in nucleus accumbens.
		BZP was a selective releaser of MPP+ (EC50 = 175 nM), whereas TFMPP was a selective releaser of 5-HT (EC50 = 121 nM).
	www.rti.org /abstract.cfm?pubid=4219 (390 words)

	TFMPP and 5-HT1B
		First, rats were trained to reliably discriminate between the stimulus properties of intraperitoneally administered 1.0 mg/kg TFMPP and its vehicle.
		Following the acquisition of this discrimination, administration of various doses of TFMPP produced a typical dose-response relationship with an ED50 of 0.27 mg/kg.
		In addition, the transfer of discrimination between TFMPP and either ethanol, THBC or MDMA appears to be asymmetrical.
	mdma.net /tfmpp (193 words)

	Schedules of Controlled Substances; Placement of 2,5-Dimethoxy-4-(n)-propylthiophenethylamine and N-Benzylpiperazine ... (Site not responding. Last check: )
		The temporary scheduling of BZP, TFMPP and 2C-T-7 which would have expired on September 19, 2003, was extended to March 19, 2004 (68 FR 53289).
		This substance has not been evaluated or approved for medical use in the U.S. The available scientific evidence suggests that the pharmacological effects of BZP are substantially similar to amphetamine.
		BZP, often in combination with TFMPP, is sold as MDMA, promoted as an alternative to MDMA and is targeted to the youth population.
	www.washingtonwatchdog.org /documents/fr/04/mr/18/fr18mr04-7.html (2267 words)

	BZP / TFMPP piperazine mix - Drugs Forum, the International Drugs Community
		I have found out that legal (in my country) smartshop pills called Charge and Rapture contain BZP and TFMPP respectivly, but I have been unable to determine the exact amount of the active ingredient in either pill.
		Have not been able to determine the exact amounts of BZP and TFMPP in the two pills.
		X Rated had 6-triflouro-N-benzyl-methyl-piperazine hcl, which I assume to be BZP and TFMPP.
	www.drugs-forum.co.uk /forum/showthread.php?t=6012 (1104 words)

	Serotonin and Hallucinogens (Site not responding. Last check: )
		That is, DOM and TFMPP were found to produce dissimilar stimulus effects in the animals.
		With the discovery of two different populations of 5-HT receptors, it was attractive to speculate that hallucinogens might represent 5-HT2 agonists whereas agents such as TFMPP and 8-OH DPAT might represent 5-HT1 agonists.
		Later, we and others came to the conclusion that TFMPP is a nonselective 5-HT agonist.
	www.phc.vcu.edu /rag/serotonin (6431 words)

	Does TFMPP ( Molly) plus BZP mimic MDMA ( Ecstasy )? (Site not responding. Last check: )
		The effects of MDMA, BZP, and TFMPP on transporter-mediated efflux of [(3)H]5-HT and [(3)H]MPP(+) (DA transporter substrate) were determined in synaptosomes.
		BZP released [(3)H]MPP(+), whereas TFMPP was a selective releaser of [(3)H]5-HT.
		Administration of BZP plus TFMPP at a 1:1 ratio (BZP/TFMPP) produced parallel increases in dialysate 5-HT and DA; a 3 mg/kg dose of BZP/TFMPP mirrored the effects of MDMA.
	mdma.net /tfmpp/tfmpp-bzp.html (257 words)

	DEA Resources, Microgram, September 2003
		Analyses by color tests, GC/MS, FT-IR, NMR, and GC/FID indicated either 1-(3-trifluoromethylphenyl)piperazine (TFMPP, calculated as the hydrochloride salt), or a mixture of TFMPP and 1-benzylpiperazine (BZP, calculated as the hydrochloride salt).
		The remaining two bags contained, respectively, 85 percent TFMPP and 7.3 percent BZP (20.7 grams), and 30 percent TFMPP and 57 percent BZP (15.5 grams).
		TFMPP and BZP have been identified numerous times at the North Central Laboratory.
	www.dea.gov /programs/forensicsci/microgram/mg0903/mg0903.html (6532 words)

Try your search on: Qwika (all wikis)