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	TSH and TRH
		The magnitude of the TSH response to TRH is modulated by the thyrotroph response to active thyroid hormone and is thus almost always proportional to the concentration of free thyroid hormone in serum.
		With the development of more sensitive TSH assays, the TRH test is generally not needed in the evaluation of a thyrotoxic patient with an undetectable TSH.407 Differential diagnosis of conditions leading to inappropriate secretion of TSH may be aided by the TRH test result.
		The TSH response to TRH, is subnormal or absent in one-third of apparently euthyroid patients with autoimmune thyroid disease, and even members of their family, may not respond to TRH.
	www.thyroidmanager.org /chapter6/Ch-6-9.htm (3903 words)

	TRH - Tennessee Rural Health
		TRH is a membership-based organization, providing high-quality health care protection at the lowest possible cost.
		TRH works hard every day to recognize and meet the needs of our members.
		TRH is the largest rural health program in the nation today, with more than 180,000 Tennesseans covered.
	www.trh.com (166 words)

	Transport and Metabolism of Thyrotrophin-Releasing Hormone Across the Fetal Membrane -- Bajoria et al. 82 (10): 3399 -- ...
		Membrane uptake of TRH was 5.02 ± 0.75%.
		TRH from the maternal to fetal circulations (2, 3, 4).
		in TRH metabolites on maternal and fetal chromatograms.
	jcem.endojournals.org /cgi/content/full/82/10/3399 (4040 words)

	Hypothyroidism induces Fos-like immunoreactivity in ventral medullary neurons that synthesize TRH -- Yuan and Yang 277 ...
		TRH, substance P, and serotonin are among the neuropeptides and transmitters that are located in the caudal raphe nuclei and
		TRH in the dorsal motor nucleus of vagus is involved in gastric erosion induced by excitation of raphe pallidus in rats.
		TRH in dorsal vagal complex mediates acid response to excitation of raphe pallidus neurons in rats.
	ajpendo.physiology.org /cgi/content/full/277/5/E927 (5307 words)

	British Journal of Pharmacology - Abstract of article: Rapid desensitization of the TRH receptor and persistent ...
		Rapid desensitization of the TRH receptor and persistent desensitization of its constitutively active mutant
		The threshold challenge caused desensitization of 50−57% of responses to subsequent supraoptimal stimulation with TRH or ACh.
		In oocytes coexpressing wild type TRH-Rs or m1-Rs with a constitutively active TRH-R mutant (C335Stop TRH-R), a persistent desensitization (33−57%) of the responses to TRH or ACh was observed.
	www.nature.com /bjp/journal/v130/n2/abs/0703291a.html (361 words)

	Triiodothyronine Down-Regulates Thyrotropin-Releasing Hormone (TRH) Synthesis and Decreases pTRH-(160-169) and Insulin ...
		TRH and insulin release and content of fetal islets cultured for 48 h in medium supplemented with either FCS or ch-FCS.
		The optical densities of the hybridization signals for TRH and insulin from independent experiments were averaged and corrected for 18S mRNA.
		on the acute release of islet TRH, pTRH-(160–169), and insulin.
	endo.endojournals.org /cgi/content/full/140/9/4113 (4403 words)

	ARUP: Thyrotropic-Releasing Hormone (TRH) Stimulation for Prolactin (Site not responding. Last check: 2007-11-02)
		The TRH test may be useful in evaluating patients with suspected pituitary disease.
		Failure of prolactin concentrations to double in response to TRH in patients with low or undetectable baseline concentrations of prolactin suggests pituitary destruction or ablation.
		Samples are obtained from alert patients using an indwelling intravenous catheter, placed 20 minutes before drawing the first blood sample, to avoid stress elevations of prolactin by the stress of venipuncture.
	www.aruplab.com /guides/clt/tests/clt_245b.jsp (242 words)

	www.drlowe.com--TRH Stimulation Test--Fibromyalgia, Hypothyroidism, Thyroid Hormone Resistance
		TRH, a hormone secreted by the hypothalamus, stimulates your pituitary gland to secrete TSH.
		When the T4 level is low, an injection of TRH causes a normal pituitary gland to secrete an unusually large amount of TSH—an amount that exceeds the upper normal level of 20.0 µIU/mL.
		The failure of your pituitary gland to secrete this increased amount in response to the TRH injection supports the hypothesis that your pituitary gland is not able to synthesize and secrete normal amounts of TSH.
	www.drlowe.com /QandA/askdrlowe/trhstim.htm (879 words)

	Joining TRH (Site not responding. Last check: 2007-11-02)
		Anyone wishing to join TRH may submit their application and annual dues of $40.00 for themselves, and their immediate family (dependent spouse and children) to the current Membership Chairperson at any meeting, event or by mailing to:
		Skull Creek Cycle Park is approximately 2000 acres of private property leased by TRH for motorcycle recreation and off-road events.
		This cost is comprised of $40 TRH membership, $160 Skull Creek membership, and $15 to defray administrative costs of the lease.
	www.trh-cycle.org /join.asp (421 words)

	Activation of MAPK by TRH Requires Clathrin-Dependent Endocytosis and PKC but Not Receptor Interaction with ...
		TRH to stimulate phosphoinositide turnover or a calcium response (24).
		A, HEK293 cells stably expressing an epitope-tagged TRH receptor were transiently transfected with 0.6 µg GFP and with 3 µg of either pcDNA3, K44A dynamin, or 319–418 ß-arrestin and grown for 24 h.
		C, HEK293 cells were transfected with 1 µg TRH receptor and 3 µg pcDNA3 (lanes 1 and 2), or with 1 µg TRH receptor and 3 µg K44A dynamin (lanes 3 and 4) or 3 µg 319–418 ß-arrestin (lanes 5 and 6).
	mend.endojournals.org /cgi/content/full/15/9/1539 (5125 words)

	The Biology of pro-Thyrotropin-Releasing Hormone-Derived Peptides -- Nillni and Sevarino 20 (5): 599 -- Endocrine ...
		TRH is implicated as a modulator of seizure activity (17) and gastrointestinal
		TRH, assuming that the TRH detected is not a cross-reactive non-TRH
		TRH is colocalized with SP and serotonin (5-HT) (128).
	edrv.endojournals.org /cgi/content/full/20/5/599 (9643 words)

	The Thyrotropin-Releasing Hormone (TRH) Hypothesis of Homeostatic Regulation: Implications for TRH-Based Therapeutics ...
		The TRH homeostatic modulatory system is comprised of four distinct, functionally integrated components including the hypothalamic-hypophysiotropic neuroendocrine system (green box), the brainstem/midbrain/spinal cord system (fl box), the limbic/cortical system (red box), and the chronobiological system (blue box).
		TRH neuronal systems are activated by the perturbed CNS function and respond by returning the system back to homeostasis.
		Sattin A (1999) The role of TRH and related peptides in the mechanism of action of ECT.
	jpet.aspetjournals.org /cgi/content/full/305/2/410 (4176 words)

	Novel TRH analog improves motor and cognitive recovery after traumatic brain injury in rodents -- Faden et al. 277 (4): ...
		The structure of the new TRH analog reported in this manuscript, together with that of YM-14673 and TRH, is given in Fig.
		To assess autonomic responses to the new TRH analog, a separate group of rats was anesthetized with 4% isoflurane (1.5 l/min).
		TRH analog was administered as a single iv bolus injection at 30 min after trauma.
	ajpregu.physiology.org /cgi/content/full/277/4/R1196 (5610 words)

	Exaggerated TSH Responses to TRH in Depressed Patients With "Normal" Baseline TSH (Site not responding. Last check: 2007-11-02)
		This may be confirmed by an exaggerated TSH response to thyrotropin-releasing hormone (TRH) on the TRH stimulation test (TRHST).
		The objective of this study was to determine the prevalence of exaggerated TRHST results in a sample of depressed patients with "high-normal" screening TSH levels.
		After baseline TSH was drawn, TRH 400 mg was injected intravenously, and TSH samples were drawn at +20 min, +30 min, and +40 min postinjection.
	www.psychiatrist.com /pasttoc/toc/june1997/266exag.htm (264 words)

	Pfam 18.0 : TRH (Site not responding. Last check: 2007-11-02)
		This interpretation is supported by the identification of a peptidase localised on the surface of neuronal cells which has been termed TRH-degrading ectoenzyme (TRH-DE) since it selectively inactivates TRH [1].
		TRH has been used clinically for the treatment of spinocerebellar degeneration and disturbance of consciousness in humans [2].
		TRH has been used clinically for the treatment of spinocerebellar degeneration and disturbance of consciousness in humans MEDLINE:12467901.
	pfam.wustl.edu /cgi-bin/getdesc?name=TRH (237 words)

	SHEBA: Logbook Entries
		Yesterday, 25 Feb when the TRH was replaced with the spare TRH the Goretex cap was left in place.
		The new TRH is in the lab and I will replace on the next visit to Baltimore.
		The TRH unit that was at Maui: TRH 006 P1110023 50Y the compass was KVH P/N 01-0177-0015, S/N 97060186 I found the coefficients for the TRH that's at Maui now.
	www.atd.ucar.edu /rtf/projects/sheba/logbook/type_TRH_entries.html (784 words)

	Purification and characterization of the thyrotropin-releasing hormone (TRH)-degrading serum enzyme and its ... (Site not responding. Last check: 2007-11-02)
		H] TRH and the inhibitors of the cytosolic
		The numbers refer to the position of the amino acid as deduced from the cDNA of rat [32] or human [37] brain TRH-DE.
		TRH is not only inactivated by one enzyme as in serum or plasma
	content.febsjournal.org /cgi/content/full/269/4/1278 (4797 words)

	Tomball Regional Hospital
		Tomball Regional Hospital is recognized as top 10% performing hospitals in the country in cardiac care and achieves center of distinction for Acute Coronary Care Syndrome by the Joint Commission on Accreditation of Healthcare Organizations.
		Sinusitis is swollen of infected linings of the sinuses, the hollow spaces in the bones of your face and skull.
		TRH is now accepting applications for Critical Care Internships.
	www.tomballhospital.org (293 words)

	TRH Gallery Homepage: About TRH
		TRH Gallery is owned and operated by Thomas R. Horvitz and specializes in comic book and comic strip original art.
		TRH Gallery is one of the few places in the comic book field that you can turn to for appraisals.
		This page and other TRH Gallery pages are copyright ©1998 Thomas R. Horvitz.
	www.trhgallery.com /about.htm (163 words)

	Cocaine- and Amphetamine-Regulated Transcript Co-Contained in Thyrotropin-Releasing Hormone (TRH) Neurons of the ...
		TRH synthesized in hypophysiotropic neurons of the hypothalamic
		TRH resulted in a marked increase of both prolactin
		TRH (3), the analysis was confined exclusively to caudal portions
	endo.endojournals.org /cgi/content/full/145/4/1695 (3010 words)

	MedlinePlus Medical Encyclopedia: TSH
		TSH is measured as a screening test for abnormal thyroid function.
		TRH, a hormone produced in the hypothalamus, stimulates the pituitary gland to release TSH.
		These hormones feedback to the hypothalamus and pituitary to regulate the release of both TSH and TRH.
	www.nlm.nih.gov /medlineplus/ency/article/003684.htm (713 words)

	Y SUN et al.: TRH receptors (Journal of Molecular Endocrinology)
		Two G protein-coupled receptors for TRH, TRH receptor type 1 (TRH-R1) and TRH receptor type 2 (TRH-R2) have been cloned from mammals.
		In this review, we compare TRH-R1 and TRH-R2 with regard to their tissue distribution, binding affinities for TRH and TRH analogs, basal and activated signaling activities and characteristics of internalization.
		TRH-R1 and TRH-R2 are distributed differently in the brain and peripheral tissues but exhibit indistinguishable binding affinities for TRH and TRH analogs.
	journals.endocrinology.org /jme/030/jme0300087.htm (214 words)

	TRH Almagro Hotel - Almagro - TRH Almagro Hotel Reviews - TripAdvisor
		TRH Almagro Hotel - Almagro - TRH Almagro Hotel Reviews - TripAdvisor
		We currently do not have any Web articles about TRH Almagro.
		If you know of a travel article about it, please let us know so we can post it here!
	tripadvisor.com /Hotel_Review-g562641-d505550-Reviews-Trh_Almagro-Al... (276 words)

	TRH-R2 Exhibits Similar Binding and Acute Signaling but Distinct Regulation and Anatomic Distribution Compared with ...
		known functions of TRH that are not transduced by TRH-R1.
		In Situ Hybridization Localization of TRH Precursor and TRH Receptor mRNAs in the Brain and Pituitary of Xenopus laevis
		Pharmacological Studies of Thyrotropin-Releasing Hormone (TRH) Receptors from Xenopus laevis: Is xTRHR3 a TRH Receptor?
	mend.endojournals.org /cgi/content/abstract/14/1/183 (692 words)

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