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Topic: Tabes dorsalis


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  Tabes Dorsalis: Encyclopedia of Neurological Disorders
Tabes dorsalis is a late manifestation of untreated syphilis and is characterized by a triad of clinical symptoms namely gait unsteadiness, lightning pains and urinary incontinence.
Tabes dorsalis is more common in middle-aged males, homosexuals and inner city population in New York, San Francisco and the southern part of the United States.
There is no trial open for tabes dorsalis, but there is an ongoing phase III multicenter randomized trial as of early 2004 funded by the National Institute of Allergy and Infectious Diseases (NIAID) for assessing the antibiotic Azithromycin given orally in treatment of primary, secondary or early latent syphilis.
health.enotes.com /neurological-disorders-encyclopedia/tabes-dorsalis   (1851 words)

  
 Tabes dorsalis - Wikipedia, the free encyclopedia
Tabes dorsalis is a slow degeneration of the nerve cells and nerve fibers that carry sensory information to the brain.
Tabes dorsalis is the result of an untreated syphilis infection.
The incidence of tabes dorsalis is rising, in part due to co-associated HIV infection.
en.wikipedia.org /wiki/Tabes_dorsalis   (241 words)

  
 Tabes dorsalis definition - Medical Dictionary definitions of popular medical terms
Tabes dorsalis: Slowly progressive degeneration of the spinal cord that occurs in the tertiary (third) phase of syphilis a decade or more after originally contracting the infection.
Among the terrible features of tabes dorsalis are lancinating lightning-like pain, ataxia (wobbliness), deterioration of the nerves to the eyes (the optic nerves) leading to blindness, urinary incontinence, loss of the sense of position, and degeneration of the joints (Charcot's joints).
The term tabes dorsalis was devised in 1836 when the cause of the condition was thought to be wastage of the dorsal (posterior) columns of the spinal cord, well before it was recognized as part of late syphilis.
www.medterms.com /script/main/art.asp?articlekey=25468   (165 words)

  
 Medical Dictionary: Tabes dorsalis - WrongDiagnosis.com
Tabes dorsalis: syphilis of the spinal cord characterized by degeneration of sensory neurons and stabbing pains in the trunk and legs and unsteady gait and incontinence and impotence
Tabes dorsalis: Parenchymatous NEUROSYPHILIS marked by slowly progressive degeneration of the posterior columns, posterior roots, and ganglia of the spinal cord.
Tabes dorsalis is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH).
www.wrongdiagnosis.com /medical/tabes_dorsalis.htm   (355 words)

  
 Baylor Neurology Case of the Month
The CSF VDRL was negative, but in tabes dorsalis it is variably reactive and tends to be normal in late, persistent, and burned out cases.
Tabes Dorsalis is a late meningoradiculitis caused by treponema pallidum, the causative organism of syphilis.
Similar findings are seen in tabes dorsalis where the inflammation of meninges and blood vessels is followed by degeneration of the posterior roots and posterior fiber columns of the spinal cord and, sometimes changes are seen in the cranial nerves.
www.bcm.edu /neurol/challeng/pat1/summary.html   (1559 words)

  
 Tresorie - THE HOMOEOPATHIC TREATMENT OF TABES AND PSEUDO-TABES [Homoeopathic Treatment Of Tabes & Pseudo Tabes]
Its patho- anatomical character is indicated in the atrophy of the posterior ligaments and of the posterior nerve roots, especially noticeable in the hip segment of the spinal marrow.
In the atrophy of the posterior ligaments Secale corn.
When in the aetiological forecast of a case of tabes the responsibility rests with sexual excess, complications early ensue, as is true in multiple sclerosis, which may pass in its incipiency for almost every form of spinal affection, and other immediate and indubitable symptoms index the origin of the trouble.
www.homeoint.org /hompath/articles/138.html   (2787 words)

  
 eMedicine - Neurosyphilis : Article by Richard P Knudsen, MD   (Site not responding. Last check: 2007-10-10)
Tabes dorsalis is a slowly progressive degenerative disease involving the posterior columns (ie, demyelination) and posterior roots (ie, inflammatory change with fibrosis) of the spinal cord.
The 3 stages of tabes dorsalis are preataxia, ataxia, and paralysis.
Reports of electrophysiologic features in tabes dorsalis indicate absent H reflexes and impeded tibial nerve sensory evoked potentials ([SEPs] with absent cortical potentials) consistent with pathologic involvement of the dorsal roots, dorsal funiculi, and posterior columns.
www.emedicine.com /neuro/topic684.htm   (5516 words)

  
 Neurological Exam: Spinal Cord: Lesions: Degenerative Diseases - Syphilis (Tabes Dorsalis)   (Site not responding. Last check: 2007-10-10)
The neurologic symptoms of tabes dorsalis usually develops 15 - 20 years after infection.
Ataxic gait and hyporeflexia are caused by purely sensory deficits due to irritation and destruction of the sensory afferents in the lumbosacral dorsal roots, affecting the incoming heavily myelinated proprioceptive fibers (later seen as demyelination in the posterior white columns).
The arthritic knee joints result from the relative insensitivity of the joints, due to destruction of the dorsal root fibers, and the resultant repeated injury; remaining pain fibers however were still sufficient to permit pain to occur.
isc.temple.edu /neuroanatomy/lab/lesions/8.htm   (409 words)

  
 s050713c - Tabes Dorsalis - Romberg's Sign
Abstract: We present a case of tabes dorsalis, which consisted of intermittent, sharp pains and diffuse neurological abnormalities, and was initially considered to be a somatoform disorder.
Discussions of the putative influence of the spinal cord on the vagaries of male sexual function, and vice versa, began with "consumption of the backbone", referred to in the Hippocratic corpus.
One may presume that the rising concern with public health and with national aims--a kind of "moral rearmament"--caused the subject to be so vigorously pursued by members of the young medical generation in early 19th-century Germany.
www.emory.edu /WHSCL/grady/amreport/litsrch05/s050713c.html   (684 words)

  
 CDC - The Medical Kipling—Syphilis, Tabes Dorsalis, and Romberg's Test
In 1858, Guillaume Duchenne wrote an almost complete clinical description of tabes dorsalis, which he named progressive locomotor ataxia, and hinted at the possibility of syphilis as the cause.
The English neurologist Sir William R. Gowers supported the causal relationship between syphilis and tabes and published the data in the Lancet in 1881 (5).
Nitrini R. The history of tabes dorsalis and the impact of observational studies in neurology.
www.cdc.gov /ncidod/EID/vol10no6/03-1117.htm   (2026 words)

  
 Bioline International Official Site (site up-dated regularly)
He also observed that, in due course of their disease, patients with tabes dorsalis tend to lose their vision and this is accompanied by worsening ataxia.
Interestingly, Benedikt has reported that the occurrence of blindness in tabes seems to prevent the development of ataxia; this is proposed to be due to an arrested pathological process (tabes fixé).
In tabes, the swaying begins as soon as the eyes are closed, occurs in all directions, and is rapid.
www.bioline.org.br /request?jp03045   (2359 words)

  
 tabes - definition by dict.die.net   (Site not responding. Last check: 2007-10-10)
tabes n : wasting of the body during a chronic disease
Tabes dorsalis[NL., tabes of the back], locomotor ataxia; -- sometimes called simply tabes.
Tabes mesenterica[NL., mesenteric tabes], a wasting disease of childhood characterized by chronic inflammation of the lymphatic glands of the mesentery, attended with caseous degeneration.
dict.die.net /tabes   (67 words)

  
 Aaron's Rod   (Site not responding. Last check: 2007-10-10)
Tabes dorsalis: A condition that results from the destruction of the dorsal columns in the spinal cord which are responsible for proprioception (position sense).
Tabes dorsalis results in a staggering wide-based gait, postural instability, pain and paresthesias.
Tabes dorsalis is a classical sign of late stage syphilis, a condition which was once common but now rarely seen since the discovery of penicillin and methods to detect early syphilis.
www.medical-library.net /vocabulary_course/full_vocabulary.html   (20496 words)

  
 Wilhelm Heinrich Erb (www.whonamedit.com)
Loss of the knee jerk as an early sign of tabes dorsalis; 2.
Absent dilatation of pupil by painful irritation of the skin in tabes dorsalis; 3.
In his works on tabes dorsalis he repeatedly sought to find the association between this disease and syphilis.
www.whonamedit.com /doctor.cfm/961.html   (1248 words)

  
 tabes dorsalis - General Practice Notebook
Tabes is a neurosyphilitic syndrome that is the result of demyelination of the dorsal roots.
The first symptoms of tabes dorsalis generally occur 8-12 years after syphilitic infection.
In this condition there is degeneration of the intraspinal portion of the posterior nerve roots.
www.gpnotebook.co.uk /simplepage.cfm?ID=-1294991357   (843 words)

  
 Tabes Dorsalis Products - Tabes Dorsalis Treatments   (Site not responding. Last check: 2007-10-10)
Tabes dorsalis; or The cause of consumption in young men and women, with an explication of its symptoms, precautions, and the method of cure: To which...
Practical essays and remarks on that species of consumption incident to youth, and the different stages of life, commonly called tabes dorsalis;: With...
Locomotor Ataxia (Tabes Dorsalis): An Introduction to the Study and Treatment of Nervous Diseases, for Students and Practitioners
goldbamboo.com /offer-t3486.html   (314 words)

  
 Tabes dorsalis: electrodiagnostic features -- Donofrio and Walker 51 (8): 1097 -- Journal of Neurology, Neurosurgery, ...
Tabes dorsalis: electrodiagnostic features -- Donofrio and Walker 51 (8): 1097 -- Journal of Neurology, Neurosurgery, and Psychiatry
Electrodiagnostic data have not been previously reported in tabes dorsalis.
A patient with tabes dorsalis is described whose nerve conduction studies
jnnp.bmjjournals.com /cgi/content/abstract/51/8/1097   (175 words)

  
 Patient 1 selftest   (Site not responding. Last check: 2007-10-10)
In tabes dorsalis, the Argyll-Robertson pupil is seen in
In tabes dorsalis, all of the following are true except
CSF pleocytosis may be present in early stages, but return to normal in later stages.
www.bcm.edu /neurol/challeng/pat1/selftest.html   (80 words)

  
 tabes dorsalis definition - Dictionary - MSN Encarta
tabes dorsalis definition - Dictionary - MSN Encarta
Search for "tabes dorsalis" in all of MSN Encarta
Tabes dorsalis is now rare because syphilis can be effectively treated at a much earlier stage.
encarta.msn.com /dictionary_1861698261_1861698244/prevpage.html   (121 words)

  
 Tabes Dorsalis Information Page: National Institute of Neurological Disorders and Stroke (NINDS)
Symptoms may not appear for some decades after the initial infection and include weakness, diminished reflexes, unsteady gait, progressive degeneration of the joints, loss of coordination, episodes of intense pain and disturbed sensation, personality changes, dementia, deafness, visual impairment, and impaired response to light.
The NINDS supports and conducts research on neurodegenerative disorders, such as tabes dorsalis, in an effort to find ways to prevent, treat, and, ultimately, cure these disorders.
Select this link to view a list of studies currently seeking patients.
www.ninds.nih.gov /disorders/tabes_dorsalis/tabes_dorsalis.htm   (347 words)

  
 Information about tabes dorsalis
The most common symptoms of tabes dorsalis are:
Pain caused by tabes dorsalis can be treated with opiates, valproate, or carbamazepine.
If left untreated, syphilis can cause tabes dorsalis.
www.mamashealth.com /neu/tabes.asp   (187 words)

  
 DR. HEINRICH OBERSTEINER (1847-1922)   (Site not responding. Last check: 2007-10-10)
He founded the Wiener Neurologische Institut in 1882 and some 400 graduate students from everywhere in the world came to study with him.
He made the classical description of concussion of the spinal cord;, described status epilepticus, wrote an important volume on general paresis and tabes dorsalis.
With Emil Redlich he demonstrated that tabes dorsalis is a disease of the posterior roots.
www.uic.edu /depts/mcne/founders/page0068.html   (124 words)

  
 Neurosyphilis
There are 4 different forms of neurosyphilis: asymptomatic, meningovascular, tabes dorsalis, and general paresis.
Asymptomatic neurosyphilis precedes symptomatic syphilis and is present in 15% of those with latent (hidden) syphilis.
In tabes dorsalis, progressive degeneration of the spinal cord occurs causing an inability to walk.
www.pennhealth.com /ency/article/000703.htm   (788 words)

  
 Neurosyphilis, tabes definition - Medical Dictionary definitions of popular medical terms
Neurosyphilis, tabes definition - Medical Dictionary definitions of popular medical terms
Neurosyphilis, tabes: Also known as tabes dorsalis, the slowly progressive degeneration of the spinal cord that occurs in the late (tertiary) phase of syphilis a decade or more after contracting the infection.
Among the terrible features are lancinating lightning-like pain, ataxia (wobbliness), deterioration of the nerve to the eye (the optic nerve) leading to blindness, urinary incontinence, loss of the sense of position, and degeneration of the joints (Charcot's joints).
www.medterms.com /script/main/art.asp?articlekey=4558   (167 words)

  
 Neurosyphilis in the modern era -- Timmermans and Carr 75 (12): 1727 -- Journal of Neurology, Neurosurgery, and ...
had definite tabes dorsalis, and one had a possible diagnosis
residual hemiparesis, one suffered from tabes dorsalis, and
In the pre-penicillin era, tabes dorsalis was the commonest
jnnp.bmjjournals.com /cgi/content/full/75/12/1727   (2230 words)

  
 Tabes Dorsalis Press Releases: National Institute of Neurological Disorders and Stroke (NINDS)
Tabes Dorsalis Press Releases: National Institute of Neurological Disorders and Stroke (NINDS)
There are no press releases for: Tabes Dorsalis.
Use your browser's Back button to return to your previous activity.
www.ninds.nih.gov /disorders/tabes_dorsalis/press_tabes_dorsalis.htm   (40 words)

  
 POX: Genius, Madness, and the Mysteries of Syphilis - Mary Todd Lincoln
Syphilis was suggested in Mary Todd’s medical history when Norbert Hirschhorn and Robert Feldman published an article in 1999 reviewing the work of the four doctors who had diagnosed her progressive spinal trouble.
P.J. Möbius went one step further: “The longer I reflect upon it, the more firmly I believe that tabes never originates without syphilis.”
Link to "Poison of the Darkness" -- article by Deb reprinted from THE NEW STATESMAN, May 2003
members.authorsguild.net /poxhistory/work9.htm   (155 words)

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