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| | Newly Approved Drug Therapies (845): Cialis (tadalafil), Eli Lilly |
 | | Cialis (tadalafil) is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) for the treatment for erectile dysfunction. |
 | | Tadalafil along with sildenafil (Viagra, Pfizer) and vardenafil (Levitra, Bayer), belongs to a class of smooth muscle relaxants called phosphodiesterase (PDE) inhibitors. |
 | | Preclinical studies showed that tadalafil is over 10,000-fold more potent for PDE5 than for PDE1, PDE2, PDE4, and PDE7 enzymes, which are found in the heart, brain, blood vessels, liver, leukocytes, skeletal muscle, and other organs. |
| www.centerwatch.com /patient/drugs/dru845.html (0 words) |
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