| |
| | Realtime Herpesvirus (Site not responding. Last check: 2007-11-04) |
 | | The HSV-1 virion comprises three concentric compartments: the capsid (100 nm in diameter, containing the viral DNA), the tegument (a shell surrounding the capsid composed of approximately 15 proteins) and the envelope (approximately 200 nm in diameter, composed of a trilamminar membrane containing 11 glycoproteins) (15). |
 | | Certain tegument proteins are located near sites within the nucleus where the capsid is constructed, consistent with the notion that they are incorporated into the virion in the nucleus (7, 29). |
 | | In contrast, other tegument proteins are located primarily in the cytoplasm, consistent with the idea that the initial nuclear envelopment of the capsid is transient and that tegument proteins are incorporated and final envelopment occurs in cytoplasmic compartments (4, 9, 10, 12, 13, 16, 30, 33). |
| thalamus.wustl.edu /willardlab/hsv.html (6943 words) |
|