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Topic: Testicular atrophy


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In the News (Fri 1 Jan 10)

  
  Testicular Atrophy
The primary etiology of testicular atrophy is surgical trauma to the testicular veins of the spermatic cord.
Given the increased incidence of testicular atrophy after recurrent hernia repair, leaders in the field of hernia repair have suggested that ³...it probably is ill advised to perform simultaneous bilateral indirect inguinal hernia hernioplasty if an indirect sac has been excised, for fear of causing bilateral testicular atrophy.
Testicular atrophy should be a rare occurrence but is nonetheless more common in recurrent hernia repairs.
www.tabexperts.com /TesticularAtrophy.htm   (701 words)

  
  MedlinePlus Medical Encyclopedia: Testicular infection or torsion   (Site not responding. Last check: 2007-10-15)
Testicular infection or torsion is a group of disorders in which testicular pain is a primary symptom.
Testicular torsion is a twisting of the spermatic cord, artery and vein, which cuts off the blood supply to the testicle and surrounding structures within the scrotum.
Testicular torsion is the most common cause of scrotal or testicular pain in boys and non-sexually active adolescents.
www.nlm.nih.gov /medlineplus/ency/article/001287.htm   (528 words)

  
 Varicocele - International Center For Vasectomy Reversal
Testicular atrophy is progressive as the young man ages.
Testicular atrophy and abnormal seminal parameters can be encountered in all these groups are patients.
The overall goal is to ligate the abnormal veins while preserving the vas deferens, testicular artery and the lymphatics of the spermatic cord.
www.dadsagain.com /varicocele.html   (1344 words)

  
 Testicular Examination and Testicular Self-Examination (TSE)
Testicular examination and testicular self-examination (TSE) are two different methods to detect lumps or abnormalities of the testicles.
Testicular self-examination (TSE) is done to familiarize a man with the normal size, shape, and weight of his testicles and the area around the scrotum.
Sudden (acute) pain or swelling in the scrotum that is noticed during the testicular examination or TSE may indicate an infection (epididymitis) or blockage of blood flow to the testicle (testicular torsion), either of which require immediate medical evaluation.
www.webmd.com /hw/mens_conditions/hw234856.asp   (1485 words)

  
 BioMed Central | Full text | Little effects of Insulin-like Growth Factor-I on testicular atrophy induced by hypoxia   (Site not responding. Last check: 2007-10-15)
Testicular atrophy was induced as previously described [10].
At baseline, both groups with testicular atrophy showed similar serum levels of albumin, cholesterol, creatinine, alkaline phosphatase, glucose, total proteins and urea, which were all normal as compared with control rats (Table 1).
A question arises as to whether the beneficial effects of IGF-I on testicular atrophy are derived from the direct action of IGF-I or these effects are an epiphenomenon secondary to the general improvement induced by IGF-I in cirrhotic animals [1,5-8].
www.biomedcentral.com /1471-2490/6/4   (4404 words)

  
 Testicular atrophy - Wikipedia, the free encyclopedia
Testicular atrophy is a medical condition in which the male reproductive organs (the testes, which in humans are located in the scrotum) diminish in size and may be accompanied by ceasing to function.
This is not used to refer to temporary changes such as those brought on by cold.
Some medications, including anabolic steroids, can cause testicular atrophy which will reverse when the course of treatment ends, provided it is not too long.
en.wikipedia.org /wiki/Testicular_atrophy   (109 words)

  
 937. Phosalone (Pesticide residues in food: 1997 evaluations Part II Toxicological & Environmental)
The incidences of unilateral or bilateral testicular atrophy in the survivors to termination were 26% in controls, 24% at the low dose, 40% at the intermediate dose, and 40% at the high dose; these percentages were stated to be within the background range in the laboratory.
Since testicular atrophy in the rat is commonly an age-related phenomenon, the prevalence of lesions in animals killed at termination is the appropriate variable; an exception would be analysis of the data in an age-to-occurrence fashion.
There was a statistically significant increase in the prevalence of testicular atrophy, a reduction in testicular weights in animals at both the high and intermediate doses, and a dose-response relationship across all groups for both effects.
www.inchem.org /documents/jmpr/jmpmono/v097pr14.htm   (1259 words)

  
 1,2-Dibromoethane (CASRN 106-93-4), IRIS, Environmental Protection Agency
Testicular atrophy in the latter group was likely to be age related, because it was not seen in 61 week controls and the duration was much longer than for exposed rats.
Because testicular atrophy occurs with high incidence in aged untreated rats, the lack of testicular atrophy in the vehicle control group at 61 weeks suggests that 1,2-dibromoethane hastens the onset of testicular atrophy.
However, because the incidence of testicular atrophy was similar at the beginning, middle and end of the study (6/20 at 9-24 wks; 4/10 at 25-39 weeks; 4/9 at 40-44 wks and 4/11 at 45-49 weeks) the dose rate may be more critical to the occurrence of this effect.
www.epa.gov /iriswebp/iris/subst/0361.htm   (8838 words)

  
 ThirdAge: Conditions InDepth: Testicular Cancer
Testicular cancer is a disease in which cancer cells grow in one or both testicles.
Testicular atrophy describes testicles that are smaller than normal in size and occurs as a result of trauma or infection.
Testicular cancer is the most common form of cancer in young men between ages 20 and 35.
www.thirdage.com /healthgate/files/20214.html   (475 words)

  
 [No title]   (Site not responding. Last check: 2007-10-15)
The examiner was to provide an opinion as to the degree of testicular atrophy of the left testis as compared to the right based on measurement of diameters and the clinical findings as to alteration of consistency of the affected left testicle.
In this particular case, service connection has been established only for left testicular atrophy as a postoperative residual of a left varicocele, and the veteran's claim for special monthly compensation for loss of use of a creative organ may currently be considered only on that basis.
Since the degree of testicular atrophy of the service-connected left testicle does not meet the requirements for an award of special monthly compensation, special monthly compensation based on loss of use of a creative organ is not warranted.
www.va.gov /vetapp/files1/9400018.txt   (1798 words)

  
 CancerNetwork.com:Cancer Screening, Diagnosis, and Treatment
Testicular feminization syndromes have been shown to increase the risk of cancer in the gonads by 40 times, and these tumors are often bilateral.
Testicular cancer is the most common malignancy in young males and frequently occurs during a crucial developmental period of their lives.
In another 20%, the testicular enlargement is painful because of bleeding or infarction in the tumor, and acute pain in a patient with a cryptorchid testis suggests torsion of a hidden mass.
www.cancernetwork.com /textbook/morev27.htm   (11268 words)

  
 BioMed Central | Full text | Little effects of Insulin-like Growth Factor-I on testicular atrophy induced by hypoxia   (Site not responding. Last check: 2007-10-15)
Testicular atrophy was induced by epinephrine (1, 2 mg/Kg intra-scrotal injection five times per week) during 11 weeks.
Testicular atrophy is a common complication in advanced cirrhosis.
At baseline, both groups with testicular atrophy showed similar serum levels of albumin, cholesterol, creatinine, alkaline phosphatase, glucose, total proteins and urea, which were all normal as compared with control rats (Table 1).
www.arabmedmag.com /issue-15-07-2006/urology/main02.htm   (4256 words)

  
 The Reproductive Toxicity of Boric Acid   (Site not responding. Last check: 2007-10-15)
Testicular boron concentrations remained steady during exposure at the same level as found in blood, and declined to background levels within 72 hr after cessation of exposure.
These studies also suggest that the potential for recovery from boric acid-induced testicular atrophy should be examined in other species to evaluate the significance of the persistent atrophy seen in the rats.
The lack of recovery in the atrophic testes, and the persistent foci of atrophy in the "recovered" tissues, may signify either a long-term alteration in the tissue or an inherent inability of rodent testis to recover from atrophy.
www.ehponline.org /members/1994/Suppl-7/chapin-full.html   (4674 words)

  
 660. Bis(2-ethylhexyl)phthalate (WHO Food Additives Series 24)
In rats, repeated administration of DEHP results in seminiferous tubular atrophy that is characterized by a loss of the meiotic and post-meiotic germ cell populations from the seminiferous epithelium (Creasey et al.
Effects of age and hormones on induction of testicular atrophy in rats were investigated by Gray & Gangolli (1986).
Specific activities of testicular enzymes associated with postmeiotic spermatogenic cells, such as lactate dehydrogenase isozyme-X, hyaluronidase, and sorbitol dehydrogenase, were lower than those of control animals by day 10, which was coincident with degeneration of spermatogenic cells in this experiment.
www.inchem.org /documents/jecfa/jecmono/v024je10.htm   (13058 words)

  
 Testicular atrophy - OhioHealth
Testicular atrophy, or shrinking of the testicles, can be due to a variety of causes, including:
Testicular atrophy can affect either or both of these tissues.
Treatment of testicular atrophy is directed at the underlying cause when possible.
www.ohiohealth.com /bodymayo.cfm?id=6&action=detail&ref=539   (254 words)

  
 eMedicine - Testicular Torsion : Article by Eugene Minevich, MD
Synonyms and related keywords: testicular torsion, intravaginal testicular torsion, extravaginal testicular torsion, torsion of the spermatic cord, torsion of the testis, epididymitis, orchitis, epididymo-orchitis, pyuria, bacteriuria, leucocytosis, contralateral orchidopexy, orchiectomy, testicular necrosis, testicular atrophy, scrotal swelling, intermittent testicular torsion, acute scrotum, bell-clapper deformity
Treat patients who are born with testicular torsion by performing early elective exploration and contralateral orchidopexy (anchoring) because bilateral (synchronous or asynchronous) neonatal testicular torsion is described.
Success in the management of spermatic cord torsion is measured by immediate testicular salvage and incidence of late testicular atrophy, which are, in turn, directly related to the duration and degree of testicular torsion.
www.emedicine.com /med/topic2780.htm   (2149 words)

  
 CTF Full Text Review: Screening for testicular cancer
Detection of a suspicious testicular mass constitutes a positive test, and the diagnosis is confirmed by biopsy and histologic examination.
Because no studies of screening for testicular cancer by physician or patient self-examination have been reported, there is insufficient evidence to include or exclude screening for this cancer in the periodic health examination of men (C Recommendation).
Patients with a history of cryptorchidism, orchiopexy, or testicular atrophy should be informed of their increased risk for developing testicular cancer and counselled about screening options.
www.ctfphc.org /Full_Text/Ch74full.htm   (1694 words)

  
 [Clinical Preventive Services] Screening for Testicular Cancer   (Site not responding. Last check: 2007-10-15)
The two screening tests proposed for testicular cancer are physician palpation of the testes and self-examination of the testes by the patient.
Detection of a suspicious testicular mass constitutes a positive test, and the diagnosis is confirmed by biopsy and histologic examination of tissue.
Patients with an increased risk of testicular cancer (those with a history of cryptorchidism or atrophic testes) should be informed of their increased risk of testicular cancer and counseled about the options for screening.
cpmcnet.columbia.edu /texts/gcps/gcps0023.html   (1501 words)

  
 DHHS (NIOSH) Publication No. 83-112   (Site not responding. Last check: 2007-10-15)
Significantly increased incidences of testicular atrophy (decreased testicular weight) and microscopic testicular changes were observed among male mice given oral doses and male mice, rats, and rabbits exposed by inhalation.
Testicular atrophy and death occurred among rabbits after 13 weeks inhalation exposure to 2ME at 300 ppm; slight to severe microscopic testicular changes were observed at 30-100 ppm.
Testicular atrophy and blood effects in 2EE-treated mice were less severe than those in mice given 2ME at the same dosage levels; testicular effects in 2EE-treated mice occurred at a lower dose than the dose causing WBC effects.
www.cdc.gov /niosh/83112_39.html   (5444 words)

  
 DHHS (NIOSH) Publication No. 79-104   (Site not responding. Last check: 2007-10-15)
Additionally, after the issuance of the June 1978 NIOSH criteria document, a 1957 study was released to NIOSH reporting testicular atrophy in laboratory rats exposed to n-butyl glycidyl ether.
NIOSH is not aware of any studies investigating the possibility of occurrence of testicular atrophy or hemopoietic abnormalities occurring in humans exposed to glycidyl ethers.
Reported testicular abnormalities (including testicular atrophy with decreased spermatogenic activity) following exposure to glycidyl ethers are presented in Table 3.
www.cdc.gov /niosh/79104_29.html   (1894 words)

  
 Groundwater Contamination along the Hanford Site Shoreline   (Site not responding. Last check: 2007-10-15)
Decreased serum levels of testosterone and compensatory increased levels of luteininzing hormone and follicle stimulating hormone were detected in all affected males; thus, the gondopituitary hormonal pathway may have responded to abnormally low levels of testosterone in the affected animals.
Testicular degeneration generally exceeded that observed with nutritional disorders and poisons in domestic species.
Testicular atrophy in mule deer has been reported elsewhere; however, prevalence has not been as high (incidences have not been as frequent) or occurrence was well confined to a specific geographical area as at the Hanford Site.
depts.washington.edu /~fmrwrkr/posters/p107d.html   (325 words)

  
 Pathbase   (Site not responding. Last check: 2007-10-15)
Patchy testicular atrophy caused by depletion of germ cells: Sertoli-cell-only syndrome.
Testicular morphology of GDNF-overexpressing mice is normal at birth.
After 2 to 3 weeks, a chimeric histological pattern is observed.
eulep.anat.cam.ac.uk /Search_Pathbase/index.php?actiontype=search&mpath=127   (43 words)

  
 1. Predisposing Factors/Prevention : BC Cancer Agency
Patients with testicular atrophy of any cause such as cryptorchism, mumps orchitis, or ectopic testis; have an increased risk for developing testis cancer.
Testicular cancer, cryptorchidism, inguinal hernia, testicular atrophy, and genital malformations: case-control studies in Denmark.
Testicular self-examination has been proposed as a method of early detection for testicular cancer but no evidence is available as to its efficiency.
www.bccancer.bc.ca /HPI/CancerManagementGuidelines/Genitourinary/Testis   (308 words)

  
 LEPORI (HCG-gonadotropin) Spain, Farma-Lepori - Steroids-Shop.Net
In the event of testicular atrophy caused by mega doses and very long periods of usage, HCG also helps to quickly bring the testes back to their original condition (size).
Since occasional injections of HCG during steroid intake can avoid a testicular atrophy, many athletes use HCG for two to three weeks in the middle of their steroid treatment.
Although HCG causes a quick and significant increase of the endogenic plasma- testosterone level, unfortunately it is not a perfect remedy to prevent the loss of strength and mass at the end of a steroid treatment.
www.steroids-shop.net /buylepori.html   (1064 words)

  
 Prevalence and Significance of Heterogeneous Testes Revealed on Sonography: Ex Vivo Sonographic--Pathologic Correlation ...
tubules, and "atrophy" as a decrease in tubule diameter and
atrophy and sclerosis was presumably caused by the chemotherapy
The presence of a testicular "halo" was unexpected and one we have
www.ajronline.org /cgi/content/full/175/2/347   (2742 words)

  
 4.26 Phosalone (T)   (Site not responding. Last check: 2007-10-15)
There was a statistically significant increase in the prevalence of testicular atrophy, a reduction in testicular weights in both the high- and middle-dose groups, and a dose-response relationship across all groups for both effects.
All testicular weights were within the historical control range of rats at the institute where the study was performed.
The slides were re-examined by a consultant, who argued that the apparent dose-response relationship for testicular atrophy was largely a product of an increase in survival among the rats at the highest dose.
www.fao.org /docrep/W8141E/w8141e13.htm   (383 words)

  
 Canadian Task Force on Preventive Health Care
Testicular cancer is the most common cancer in men aged 15 to 34 years, and the incidence has been rising only in this age group.
It is uncertain whether earlier orchiopexy (prior to school age), which is now common practice, will prevent development of testicular cancer.<14> One study found carcinoma in situ in 1.7% of men with a history of cryptorchidism who had testicular biopsies.
They projected that 50% of these lesions would progress to invasive cancer and recommended testicular biopsy be offered all men with a history of cryptorchidism.<15> Many experts recommend that intra-abdominal testes should be removed.<3> The survival for patients with a history of cryptorchidism who develop testicular cancer is excellent as it is in non-cryptorchid patients.
www.ctfphc.org /Full_Text_printable/Ch74full.htm   (1540 words)

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