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Topic: Tetrahydrogestrinone

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	Tetrahydrogestrinone (THG) Profile
		Tetrahydrogestrinone (often referred to as THG or the "Clear") is a potent anabolic and progestagenic androgenic steroid that is chemically and structurally related to two other synthetic anabolic steroids, gestrinone and trenbolone (1).
		The use of tetrahydrogestrinone (THG) by several elite athletes led the US Congress to add it to the Anabolic Steroid Control Act of 2004 as a "Schedule III" controlled substance.
		THG, although pharmacologically defined as an anabolic-androgenic steroid, was legally defined as an "unapproved new drug" during its role in the BALCO scandal.
	www.mesomorphosis.com /steroid-profiles/tetrahydrogestrinone.htm (460 words)

	Tetrahydrogestrinone - Wikipedia, the free encyclopedia
		Tetrahydrogestrinone (often referred to as THG or "the clear") is an anabolic steroid.
		It has affinity to the androgen receptor and the progesterone receptor, but not to the estrogen receptor.
		tetrahydrogestrinone was unscrupulously brought to the European athletic scene.
	en.wikipedia.org /wiki/Tetrahydrogestrinone (422 words)

	FDA bans the sale of designer steroid THG
		The new drug, tetrahydrogestrinone, or THG, is not a dietary supplement, the federal agency said, but a "purely synthetic designer steroid" derived from another banned steroid.
		Taylor, associate commissioner of food and drugs for regulatory affairs, testified before Congress on Tuesday that tetrahydrogestrinone is derived from gestrinone, a drug banned by the U.S. Anti-Doping Agency.
		Tetrahydrogestrinone is made by the Bay Area Laboratory Co-Operative, a Burlingame, Calif., company owned by Victor Conte, a former track athlete who was a bassist known as Walkin' Fish with the funk band Tower of Power before he started Balco to offer "nutritional testing and counseling" to athletes.
	www.rxlist.com /rxboard/prozac.pl?noframes;read=941 (1056 words)

	FDA moves on antidepressant—suicide link, new steroid
		Whether antidepressant therapy is a cause of suicidal thinking and attempts remains unclear, and FDA hopes it clear the air at a mid-winter advisory panel hearing, the agency said yesterday.
		But another fact is crystal clear, FDA is maintaining: the newly recognized anabolic steroid tetrahydrogestrinone is an unapproved drug and not a dietary supplement.
		Tetrahydrogestrinone is a synthetic “designer” steroid derived by simple chemical modification of an agent banned by the U.S. Anti-Doping Agency, FDA explained in a statement posted to the Web.
	www.pharmacist.com /articles/h_ts_0401.cfm (340 words)

	THG on banned list, say WADA, IOC
		The newly discovered designer steroid tetrahydrogestrinone (THG), the focus of a doping scandal in world sport, is on the list of prohibited substances, the World Anti-Doping Agency (WADA) and International Olympic Committee (IOC) said on Wednesday.
		"Following the recent developments regarding the anabolic steroid tetrahydrogestrinone (THG), the International Olympic Committee and the World Anti-Doping Agency have advised all stakeholders that THG is a steroid contained in the present and next year's List of Prohibited Substances," WADA and the IOC said in a statement on their web sites.
		Tetrahydrogestrinone is a specially designed anabolic steroid that has been tweaked by chemists to make it undetectable under normal testing.
	www.velonews.com /news/fea/5217.0.html (284 words)

	Dwain Chambers interview
		Tetrahydrogestrinone (THG) is a recently discovered steroid that has never been marketed and is used unlawfully to enhance sports performance.
		Tetrahydrogestrinone (18a-homo-pregna-4,9,11-trien-17beta-ol-3-one or THG) was identified in the residue of a spent syringe that had allegedly contained an anabolic steroid undetectable by sport doping control urine tests.
		Tetrahydrogestrinone (THG), a substance taken by athletes to improve their performance, is considered to be an unapproved drug by the FDA, and cannot be legally marketed.
	www.muscletalk.co.uk /m_836661/printable.htm (2945 words)

	FDA Statement on THG
		The Food and Drug Administration (FDA) has recently been made aware of a substance called tetrahydrogestrinone (THG), which is reportedly used by athletes to improve their performance.
		Based on the agency's analysis of this product, FDA has determined that THG is an unapproved new drug.
		Anabolic steroids, which build muscle mass, can have serious long-term health consequences in men, women, and children.
	www.fda.gov /bbs/topics/NEWS/2003/NEW00967.html (279 words)

	RTÉ.ie Sport - Californian laboratory under investigation
		The Bay Area Laboratory Co-Operative in California, which is at the centre of the drug scandal which has rocked world athletics in the past week, is being investigated for allegedly receiving millions of dollars in return for undetectable performance-enhancing drugs.
		The inquiry into the labratory, based in Burlingame, California, has been brought about by new tests, currently being developed in the United States, that are able to reveal the banned anabolic steroid THG (tetrahydrogestrinone), a previously undetectable substance.
		Victor Conte, head of BALCO, was named by an anonymous track coach as the source of a substance which turned out to be tetrahydrogestrinone, or THG, a previously undetectable steroid.
	www.rte.ie /sport/2003/1022/athletics01.html (173 words)

	THG or tetrahydrogestrinone, the undetectable anabolic steroids.
		I'll start by saying, "No, THG (tetrahydrogestrinone) is not for you, and you can't buy it anywhere".
		Tetrahydrogestrinone is a designer steroid used only by elite athletes.
		Tetrahydrogestrinone, no one is certain how long this drug has been used, but tests are now being down on urine samples from the 2002 olympics.
	www.steroidworld.com /tetrahydrogestrinone.htm (1034 words)

	Anabolic-Androgenic Steroids and Testosterone Precursors: Ergogenic Aids and Sport
		Increasing attention is also being paid to the long-term effects of AAS abuse, as more authors characterize the changes to hematologic, hepatic, lipid, and hormone profiles as a result of years of steroid use.
		Advances in the field of drug testing is discussed, as is the discovery of a designer steroid, tetrahydrogestrinone (THG), in October 2003, as the scientific community attempts to keep up with the ever-evolving world of performance enhancement.
		The discovery of THG was serendipitous and possible because a used syringe, containing a substance purported to be an undetectable steroid, was sent to the USADA in mid-summer by an unnamed track and field coach [41].
	www.current-reports.com /article.cfm?PubID=SR03-4-2-04&Type=Article&KeyWords= (4808 words)

	ABC Sport - Sport - Factbox on steroid THG
		Factbox on steroid tetrahydrogestrinone (THG), the drug at the centre of the latest doping scandal to hit sport.
		The world governing athletics body announced on Tuesday it would re-test all urine samples from the Paris world championships in August after the discovery in the US of the previously undetectable drug.
		Tetrahydrogestrinone is a specially designed anabolic steroid which has been tweaked by chemists to make it undetectable under normal testing.
	www.abc.net.au /sport/content/s972132.htm (420 words)

	rediff.com sports channel: The Year That Was
		The year ended with a US federal grand jury investigating BALCO, a San Francisco Bay area laboratory believed to be at the heart of a doping scandal that has rocked the sports world.
		The discovery of the designer steroid THG (tetrahydrogestrinone) and a test to detect it sent tremors across the sport domain.
		Leagues and governing bodies from Major League Baseball to the International Olympic Committee scrambled to add THG to their banned substances list and, in many cases, retest athletes' urine samples.
	www.rediff.com /sports/2003/dec/19pic4.htm (154 words)

	ABC Sport - Sport - Chambers vows to fight drug charge
		British sprinter Dwain Chambers, the European 100 metres record holder, has insisted he is not a drugs cheat despite testing positive for the banned designer steroid tetrahydrogestrinone (THG) at the heart of a new US doping scandal.
		Three of them competed at the World Championships in August at Paris, although none of them captured a medal, Masback added, saying those four were the only THG positives he knew about.
		Chambers discovered he had tested positive for tetrahydrogestrinone earlier this month and is now waiting for a second sample to be tested.
	www.abc.net.au /sport/content/s973113.htm (980 words)

	RedOrbit - Health - Cardiovascular Toxicities of Performance-Enhancing Substances in Sports (Site not responding. Last check: )
		Despite the efforts of athletic regulatory and governing bodies to restrict the use of performance-enhancing substances, use of these substances has increased.2 Meanwhile, the mechanisms and the clinical manifestations of toxicity of anabolic steroids, ephedra, erythropoietin, and other performance-enhancing agents were acknowledged.
		Tetrahydrogestrinone (THG) has received considerable media attention recently for its use as a performance-enhancing substance.
		Tetrahydrogestrinone is known to be considerably more hepatotoxic than other steroids; its cardiac effects have not been investigated yet but are believed to be similar to those of other steroids.57 Data are insufficient regarding the ergogenic effects of THG.
	www.redorbit.com /news/health/262298/cardiovascular_toxicities_of_performanceenhancing_substances_in_sports/index.html?source=r_healt (4493 words)

	Tetrahydrogestrinone Is a Potent Androgen and Progestin -- Death et al. 89 (5): 2498 -- Journal of Clinical ...
		Tetrahydrogestrinone Is a Potent Androgen and Progestin -- Death et al.
		Tetrahydrogestrinone (THG) was recently identified as a novel
		Tetrahydrogestrinone induces a genomic signature typical of a potent anabolic steroid
	jcem.endojournals.org /cgi/content/abstract/89/5/2498 (334 words)

	The Telegraph - Calcutta (Site not responding. Last check: )
		London: Britain’s European 100 metres champion Dwain Chambers was banned for two years on Tuesday after failing a test for the new designer steroid THG.
		Chambers, 25, tested positive for tetrahydrogestrinone (THG) in an out-of-competition test last August.
		Four American track and field athletes have also tested positive for the steroid, which was discovered in a Los Angeles laboratory last year.
	www.telegraphindia.com /1040225/asp/sports/story_2935023.asp (289 words)

	CNN.com - 4 U.S. athletes positive for THG - Oct. 23, 2003
		Four American athletes have tested positive for the designer anabolic steroid tetrahydrogestrinone (THG) as U.S. Track and Field chiefs plan major new measures to combat drugs cheats.
		And the World Anti-Doping Agency (WADA) confirmed that the method for detecting the "designer" steroid at the heart of the sport's latest doping scandal is being sent to IOC-accredited laboratories throughout the world.
		Distribution of the test for tetrahydrogestrinone means 30 labs will be able to test for the latest sophisticated doping device.
	www.cnn.com /2003/SPORT/10/22/drugs.tests (432 words)

	Rapid communications in mass spectrometry
		They were then able to synthesize a compound with this formula, which they named tetrahydrogestrinone (THG) and which matched the unknown substance in the syringe.
		Urine samples were purposely spiked with the newly identified THG and various analyses carried out to determine how the substance could be detected.
		Article: "Tetrahydrogestrinone: discovery, synthesis and detection in urine." D.H. Caitlin, M.H.Sekera, B.D. Ahrens, B. Starcevic, Y.C. Chang, C.K. Hatton; Rapid Communications in Mass Spectrometry; Vol 18(12).
	www.medicalnewstoday.com /medicalnews.php?newsid=8326 (650 words)

	2003 Sportsman Of The Year: Tetrahydrogestrinone
		They all stood tall, but the biggest influence was wielded by a previously unknown performance-enhancing drug called Tetrahydrogestrinone, or THG.
		Created in BALCO Laboratories by Victor Conte, THG was made possible by modern medical science, and in many ways, made 2003 possible.
		That’s why the Brushback has named Tetrahydrogestrinone its 2003 Sportsman of the Year.
	www.thebrushback.com /Archives/sportsmanofyear_full.htm (1032 words)

	C&EN: Latest News - Second 'Designer' Steroid Uncovered
		Desoxymethyltestosterone is the second known “designer” steroid, after tetrahydrogestrinone.
		The first two were norbolethone and tetrahydrogestrinone (THG), which were identified in 2002 and 2003, respectively, by chemists at the Olympic Analytical Laboratory at the University of California, Los Angeles (CandEN, Nov. 17, 2003, page 66).
		The Montreal lab, directed by Christiane Ayotte, has collaborated with medicinal chemist Donald Poirier and his group at the University of Laval, in Sainte-Foy, Quebec, to further study DMT and to work out a possible synthesis.
	pubs.acs.org /cen/news/83/i07/8307steroids.html (506 words)

	RTÉ.ie Sport - FINA to look into THG tests
		World swimming federation FINA said today that samples taken during July's world championships in Barcelona could be tested again for tetrahydrogestrinone (THG).
		The emergence of THG, a previously undetectable steroid, has prompted the IAAF, the governing body of world athletics, to re-test all urine samples taken during the world championships held in Paris in August.
		FINA said that they have consulted an International Olympic Committee (IOC) approved laboratory in Barcelona over performing THG tests if experts decide the samples should be re-tested.
	www.rte.ie /sport/2003/1029/thg.html (164 words)

	Designer Steriods: THG
		Tetrahydrogestrinone (THG) is the official name for the designer steroid, which apparently has been used without fear of detection for some time by athletes around the world.
		Use of THG was discovered in 2003 after the United States Anti-Doping Agency received a tipoff from leading track coach Trevor Graham.
		Contact a health professional if you find yourself having problems that seem health related or beyond your current coping skills.
	www.lovingmiracles.com /nutrition_articles/designers_steroids.htm (885 words)

	Youth Lacrosse USA \| Home of Lacrosse - YouthLax.com (Site not responding. Last check: )
		REGINA (CUP) - A new drug has been discovered and is taking the sporting world by storm.
		It would appear that the drug of choice today is tetrahydrogestrinone, or THG for short.
		If no clean athlete can be found, then let the steroid-enhanced games begin.
	www.youthlacrosseusa.com /generalnews/111103_newdrug.html (619 words)

	Kevin Toth - Wikipedia, the free encyclopedia
		His personal best throw is 22.67 meters, which places him 7th on the all-time performers list (see [1]).
		In 2003 he tested positive for tetrahydrogestrinone and received a two-year ban from 2004-2006 (see [2]).
		Toth attended Friendswood High School in Friendswood, Texas and was a letterman in football and track.
	en.wikipedia.org /wiki/Kevin_Toth (135 words)

	CBC Sports Online: Drugs and Sport: How the THG scandal unfolded
		THG, short for tetrahydrogestrinone, is a new steroid at the centre of a major controversy that threatens to turn the sports world on its ear.
		THG would have remained sports' dirty little secret had it not been for the actions of an unidentified insider who blew the whistle.
		Now, because of that person's actions, tetrahydrogestrinone is the one word on the lips of everybody in the sports world.
	www.cbc.ca /sports/indepth/drugs/stories/thg_timeline.html (1584 words)

	ESPN.com - NBA - NBA puts THG on banned-substance list
		League spokesman Tim Frank confirmed the new policy Friday, saying: "The NBA and the NBA Players Association have agreed to add THG and gestrinone to the banned-substances list under the league's anti-drug policy beginning with the 2004-05 season.
		Formal tests for THG, also known as tetrahydrogestrinone, will start in training camp next October.
		The steroid has caused widespread scandal in the track and field community, but one Western Conference All-Star told ESPN.com that he would be surprised to hear that NBA players are using the drug.
	proxy.espn.go.com /nba/columns/story?columnist=stein_marc&id=1723396 (235 words)

	CNN.com - Ferdinand case is on FIFA's agenda - Oct. 27, 2003
		Potential punishments for England defender Rio Ferdinand will be among topics discussed by FIFA's sports medical committee on Tuesday.
		The impact on football of the designer drug tetrahydrogestrinone (THG) is also on the agenda along with another 25 cases and issues of doping-related cases from around the world.
		Ferdinand has claimed he forgot to give a sample at Manchester United's training ground on September 23.
	cnn.com /2003/SPORT/football/10/27/ferdinand.test/index.html (355 words)

	Teen At Party Pressured Into Trying Steroids
		With so many big stars suspected of injecting the designer chemicals, many feared that children and teens would follow suit.
		It appears those fears were justified, as a recent survey suggests that over 87 percent of US teens have experimented with the popular drug Tetrahydrogestrinone.
		Our fears have been realized,” said Eugene Montague, national director of D.A.R.E. “THG and other designer performance enhancers have become extremely popular, and the concern is that they will replace ecstasy as the club drug of choice.
	www.thebrushback.com /Archives/teenatparty_full.htm (736 words)

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