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| | Th2-shift in schizophrenia: primary findings from whole blood in vitro production |
 | | In determining an immune response, the balance between two T helper lymphocyte subpopulations, Th1 and Th2, is believed to be pivotal and is therefore critical for the host defense and the pathogenesis of immune-mediated diseases (Agnello et al., 2003; McGuirk and Mills, 2002). |
 | | A few studies examined another main Th2 cytokine, IL-10, and demonstrated to be either unaltered (Cazzullo et al., 2002; Rothermundt et al., 1998) or augmented (Cazzullo et al., 1998). |
 | | Regardless of the role of cortisol in the cognitive function, cortisol seemed not to be the key reason for the Th2-shift in female schizophrenics because it was reported to induce a shift from Th1 to Th2 (Visser et al., 1998; Franchimont et al., 1998). |
| www.priory.com /psych/th2.htm (3463 words) |
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