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	A responsibility of the state and community: Thalassaemia prevention (Site not responding. Last check: 2007-10-09)
		Thalassaemia is the commonest inherited disorder in Pakistan.
		The most frustrating aspect of thalassaemia major is that the parents of a child having this disease are aware by his first birthday that the child is not going to survive beyond 25-30 years.
		Thalassaemia, in our country, runs in families and 'Braderies' as 'cousin marriages' are common and the fact that carrier often remain unidentified because of asymptomatic nature of thalassaemia minor.
	www.telmedpak.com /generalpublicarticles.asp?a=1760 (1337 words)

	Big B joins thalassaemia eradication drive- The Times of India (Site not responding. Last check: 2007-10-09)
		thalassaemia is an inherited blood condition in which there is a reduced synthesis of haemoglobin (see box).
		it is the thalassaemia major child who requires frequent blood transfusions, besides medicines (iron chelating agents) to prevent excess deposition of iron on vital organs.
		so in cases where both the husband and wife are thalassaemia minor and expecting a child, we at rvbb send them to mumbai for sonography which can detect if the child to be born is thalassaemia major or not.
	timesofindia.indiatimes.com /articleshow/msid-1853363666,prtpage-1.cms (777 words)

	Sarawak Thalassaemia Online: What is Thalassaemia (Site not responding. Last check: 2007-10-09)
		As the general public is still largely ignorance of existence of thalassaemia, it is one of our objectives to spread more public awareness of this fatal blood disorder.
		If a person has the thalassaemia trait, many of his or her relatives may also have it.
		Thalassaemia is a genetic blood disorder whereby the blood cells are unable to carry a sufficient supply of oxygen for the body’s needs:
	www.thalassaemia.cdc.net.my /thalassaemia.html (192 words)

	Alt NoFrames Thalassaemia HomePage (Site not responding. Last check: 2007-10-09)
		Thalassaemia is a public health problem among the Malays and Chinese of Malaysia where Indians form only a small percentage of those with thalassaemia.
		thalassaemia gene from each parent usually develop the clinical manifestations of thalassaemia major, a severe anaemia requiring regular blood transfusions for survival.
		The clinical manifestations of the thalassaemia syndromes result from ineffective erythropoiesis and shortened red blood cell survival, which in turn are caused by unbalanced globin chain synthesis.
	webcrawler.tripod.com /noframes3.htm (1791 words)

	What is Thalassaemia? (Site not responding. Last check: 2007-10-09)
		Thalassaemia is a inherited disorder of the haemoglobin.
		Thalassaemia is an inherited disorder in which there is an abnormality in one or more of the globin genes.
		Thalassaemia minor will never go away, people who think they have Thalassaemia minor or are at risk (Background of Mediterranean decent) should have a blood test so in the future they can be aware for themselves in terms of not having a Thalassaemia major child.
	www.dibbo.org /what.html (2444 words)

	Kids health info for parents : Thalassaemia
		Thalassaemia trait is present at birth, it remains the same for life, and it can be handed on from parents to children.
		If both your child and his/her future partner are carriers of the thalassaemia trait, there is a danger for their children, but this can be avoided by planning the family carefully with the help of a doctor.
		Thalassaemia is seen in all populations but is more common in people of Mediterranean, Middle Eastern and South East Asian descent.
	www.rch.org.au /kidsinfo/factsheets.cfm?doc_id=3734 (1160 words)

	Clinical Practice Guidelines : Thalassaemia and Abnormal Haemoglobins in Pregnancy
		Mothers with thalassaemia disease or severe haemoglobinopathy syndromes are referred to the MFM Obstetrician attached to the Thalassaemia Clinic for pregnancy care.
		Haemoglobinopathies (comprising the thalassaemias and abnormal haemoglobins) are hereditary disorders which affect the balance of globin chain synthesis and/or the structure of haemoglobin.
		The aim of screening couples for thalassaemia is to detect those at risk of having children with severe disease, with a view to offering prenatal diagnosis and the option of termination of pregnancy in the event of a positive diagnosis.
	www.rwh.org.au /rwhcpg/maternity.cfm?doc_id=3200 (876 words)

	Abnormal Laboratory Results - Screening for thalassaemia (Site not responding. Last check: 2007-10-09)
		The thalassaemias are the commonest single gene disorders in the world's population and are a common cause of hereditary anaemia.
		The thalassaemia syndromes are usually caused by point mutations or deletions in, or close to, these globin genes which reduce or abolish expression of the affected gene.
		The laboratory diagnosis of the thalassaemia carrier state is therefore of increasing importance both for antenatal diagnosis and for clinical management.
	www.australianprescriber.com /magazines/vol24no5/abnormal.htm (2593 words)

	Thalassaemia
		Thalassaemia is a disorder that affects the production of haemoglobin and results in severe anaemia.
		Thalassaemia can affect anyone of any nationality, but it is particularly prevalent in people from Mediterranean countries and a broad region extending across the Middle East and South East Asia.
		Thalassaemia is usually diagnosed within the first six months of life and can be fatal in early childhood without ongoing treatment.
	www.betterhealth.vic.gov.au /BHCV2/bhcarticles.nsf/pages/Thalassaemia?open (767 words)

	thalassaemia (Site not responding. Last check: 2007-10-09)
		Thalassaemia is an inherited disorder of the blood.
		The main problem with thalassemia is a reduction in the amount of globin being formed, and thus potentially a diminished ability of the blood to transport gases around the body.
		The genetic basis for each is established at the time of conception, so it is not possible for thalassaemia of one type to transform into another type during the person’s lifespan.
	www.nurseminerva.co.uk /thalassa.htm (1439 words)

	Carrying Beta Thalassaemia - Information for people who have had a blood test that shows they carry Beta Thalassaemia (Site not responding. Last check: 2007-10-09)
		Beta thalassaemia is inherited - it is handed on from parents to their children, it is present at birth, and it remains the same for life.
		Some women who carry beta thalassaemia have a mild anaemia that has nothing to do with the amount of iron they are getting from their food.
		Beta thalassaemia does not go away when malaria disappears, or when carriers move to a different part of the world, because it is inherited.
	www.cmht.nwest.nhs.uk /directorates/nebata/carrying.asp (1666 words)

	U.K. Thalassaemia Society
		Carriers of beta thalassaemia are normally healthy and will not know that they are carriers unless they have a special blood test to detect this condition.
		If a person is a carrier of beta thalassaemia and has a blood test for some other reason the fact that they carry beta thalassaemia is not known, it may be confused with other conditions and lead to unnecessary tests and/or treatment.
		Before a person who is a carrier of beta thalassaemia decides to have children it's advisable for them to find out as soon as possible if their partner is also a carrier of beta thalassaemia or another interacting haemoglobin such as sickle haemoglobin (Hb S), Hb O Arab or Hb Lepore.
	www.ukts.org /pages/carrier.htm (378 words)

	[No title]
		Figure 12.4: Differential diagnosis of thalassaemia major and intermedia Clinical manifestations Three main factors are responsible for the clinical manifestations of thalassaemia intermedia: a) ineffective erythropoiesis, b) chronic anaemia, c) iron overload.
		Moreover, patients with thalassaemia intermedia suffer from various complications which are very uncommon in optimally transfused thalassaemia major patients, such as folic acid deficiency, leg ulcers, gallstones and thrombosis.
		Older patients with thalassaemia intermedia may have the same risk for iron-induced hepatic, cardiac and endocrine dysfunction as in patients with thalassaemia major.
	www.thalassaemia.org.cy /books/book1/ch11.doc (1529 words)

	Default
		Thalassaemia is an inherited blood disease transmitted by a gene.
		Thalassaemia major is a severe form of anemia.
		Thalassaemia major is transmitted by two Thalassaemia genes, one from the father one from the mother.
	www.sabah.org.my /scss/thala/default.htm (555 words)

	Bhanushalis fight thalassaemia with pre-marriage blood-test (Site not responding. Last check: 2007-10-09)
		The Bhanushalis, a Kutchi community in which 13 per cent are either afflicted with or carriers of thalassaemia, have decided to fight the hereditary disease by insisting that couples undergo blood test before marriage so that a carrier does not end up marrying another.
		Thalassaemia is the term used for a range of hereditary diseases caused by faulty haemoglobin synthesis.
		Thalassaemia majors, or those in whom the disease is manifest, have to undergo fortnightly blood transfusions but rarely survive beyond 20 years.
	cities.expressindia.com /fullstory.php?newsid=128345 (628 words)

	Thalassaemia - Patient UK
		Beta thalassaemia major is the most serious of the beta thalassaemia diseases and occurs when a person has inherited the beta thalassaemia haemoglobin genes from both parents (one from each parent).
		People with beta thalassaemia major still absorb iron from the food they eat, they also get iron from the blood transfusion, so they have too much iron in the body, this is called 'iron overload'.
		The psychological and emotional stress of living with beta thalassaemia major can be reduced if individuals and families try to live as normal a life as possible, whilst coping with the demands of the disease.
	www.patient.co.uk /showdoc.asp?doc=23068993 (1656 words)

	MENAFN - Middle East North Africa . Financial Network News: Senior medical officials said that women should be able to ... (Site not responding. Last check: 2007-10-09)
		Financial Network News: Senior medical officials said that women should be able to legally abort a foetus suffering from thalassaemia within the first four months of pregnancy...
		Senior medical officials said that women should be able to legally abort a foetus suffering from thalassaemia within the first four months of pregnancy...
		Thalassaemia causes severe anaemia by reducing the body's ability to produce haemoglobin, a protein that carries oxygen.
	www.menafn.com /qn_news_story_s.asp?StoryId=100827 (295 words)

	babyworld - your baby - special needs - thalassaemia (Site not responding. Last check: 2007-10-09)
		Thalassaemia is a blood disorder in which there is an abnormal amount of haemoglobin (the substance that carries oxygen in the blood) in the red blood cells.
		There are several different forms of thalassaemia and the severity of the anaemia varies with each form, from mild to extremely severe.
		Thalassaemia is found most commonly in people of Mediterranean, Middle Eastern and Asian origin.
	www.babyworld.co.uk /information/baby/special_needs/thalassaemia.htm (270 words)

	The Project: Sickle Cell & Thalassaemia Support Project Wolverhampton
		Sickle cell and thalassaemia disorders are both blood disorders (haemoglobinopathies) affecting haemoglobin (the oxygen-carrying substance in red blood cells).
		Thalassaemia is an inherited condition of the blood, which affects the production of haemoglobin - an oxygen-carrying substance that gives blood its red colour.
		If both parents have sickle cell or thalassaemia trait, there is a one in four chance (25%) that in each pregnancy the child will have sickle cell or thalassaemia disorder.
	www.angelfire.com /sc3/wton/03_sicklecell.html (343 words)

	Drive to eradicate thalassaemia on in Saurashtra :: Gujarat Plus.com News
		A high-prone zone of beta thalassaemia major, the most severe form of the disorder, the region is known to have at least 11 per cent of its population afflicted by the disease.
		Although thalassaemia is prevalent world-wide, it is the single most common genetic disorder affecting all ethnic backgrounds and geographic regions in the Indian subcontinent.
		Indrani Jani, in charge of counseling, says "Students found to be thalassaemia minor will be counselled so that tomorrow when they decide to get married and plan a family they are aware and would want to find out if their partner is also a thalassaemia minor.
	www.gujaratplus.com /news/Rajkot/92776.html (774 words)

	Screening: Sickle Cell & Thalassaemia Support Project Wolverhampton
		Children with Thalassaemia Major are severely anaemic and need blood transfusions every four weeks and regular injections for life.
		Both Sickle Cell and Thalassaemia disorders exist in two forms; one is the disorder form and the other is the carrier form (trait).
		The Sickle Cell and Thalassaemia Support Project also provides genetic counselling which enables individuals the opportunity to discuss their results and any implications it may have on the family.
	www.angelfire.com /sc3/wton/13_screening_english.html (559 words)

	Psychology web site of Sickle Central (Site not responding. Last check: 2007-10-09)
		Thalassaemia is characterised by the absence or reduction in the production of haemoglobin.
		Severity is variable from mild anaemia, through "thalassaemia intermedia", to profound severe anaemia (thalassaemia major).
		In thalassaemia major other complications include growth retardation and bone deformation.Blood Transfusion is required to treat severe forms of thalassaemia and some complications of sickle cell disease.
	www.sickle-psychology.com (298 words)

	City - Marriage vow to fight thalassaemia (Site not responding. Last check: 2007-10-09)
		The couple have organised a thalassaemia screening and blood donation camp on Sunday in memory of their son Teerth.
		Note: The thalassaemia screening and blood donation camp will be held at Paradise Apartments, 7th Road, Khar, from 9 am onwards on Sunday.
		Thalassaemia major and minor are hereditary disorders characterised by defective production of haemoglobin, which leads to decreased production and increased destruction of red blood cells.
	web.mid-day.com /news/city/2002/december/38855.htm (564 words)

	Thalassaemia
		Clinically they are divided into hydrops foetalis, β-thalassaemias major, thalassaemia intermedia and thallassaemia minor, the usually symptomless carrier.
		Thalassaemia major is often due to inheritance of two different mutations, each affecting β-globin synthesis (compound heterozygotes).
		The patient with thalassaemia interedia may show bone deformity, enlarged liver and spleen, extramedullary erythropoiesis and features of iron overload due to increased iron absorption.
	www.ucy.ac.cy /~deltas/cyprusgmd/diseases/Thal.htm (712 words)

	Will I pass on thalassaemia alpha to my children? - Miscellaneous - DoctorNDTV
		Homozygous alpha+ thalassaemia or --/a a alpha0 thalassaemia trait
		The loss of two genes (two-gene deletion alpha thalassaemia) produces a condition with small red blood cells, and at most a mild anaemia.
		Your husbands CBC does not suggest a thalassaemia trait but both of you need to consult a haematologist who will be able to advise you appropriately as alpha thalassaemia trait (one or two gene deletion alpha thalassaemia) can only be ascertained by a specialised DNA analysis.
	www.doctorndtv.com /faq/detailfaq.asp?id=4520 (583 words)

	Lipids in Health and Disease \| Full text \| Distribution of serum lipids and lipoproteins in patients with beta ...
		Beta thalassaemia major (b-TM) is a very serious blood condition since individuals with it are unable to make enough healthy red blood cells and depend on blood transfusions all their life.
		At this point it should be noted that the extrapolation of our findings into other populations with beta thalassaemia major may be under scrutiny, since thalassaemia is genetically oriented and various expressions of the related polymorphisms may be involved in the distribution of blood lipids and lipoprotein levels.
		The present study revealed that men and women with beta thalassaemia major have their blood lipid and lipoprotein levels within the normal range, and lower than the healthy individuals of the same age and population.
	www.lipidworld.com /content/3/1/3 (3733 words)

	Iranian national thalassaemia screening programme -- Samavat and Modell 329 (7475): 1134 -- BMJ
		Use of a national diagnosis register for surveillance of an inherited disorder: the example of beta thalassaemia in the United Kingdom.
		Informed choice in genetic screening for thalassaemia during pregnancy: audit from a national confidential enquiry.
		Akbari M, Izadi P. The incidence of beta thalassaemia gene mutations and prenatal diagnosis in Iran.
	bmj.bmjjournals.com /cgi/content/full/329/7475/1134 (2098 words)

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