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Topic: The Institute for Genomic Research

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Craig Venter

Origin of life

John I of Portugal

	Microbial Genomics Research Projects
		Pyrococcus horikoshii: DOGAN, a genome database of microorganisms sequenced at NITE
		GeneDB: multiorganism database housing fungi, protozoa, bacterial and vector genomes
		Staphylococcus aureus MW2: DOGAN, a genome database of microorganisms sequenced at NITE
	microbialgenomics.energy.gov /links.shtml (2389 words)

	The Institute for Genomic Research
		The Institute for Genomic Research (TIGR) is a not-for-profit center dedicated to deciphering and analyzing genomes – the complex molecular chains that constitute each organism’s unique genetic heritage.
		Since it was founded in 1992, TIGR has been at the forefront of the genomics revolution, deepening the understanding of life and producing results with wide-ranging applications in medicine, agriculture, energy, the environment and biodefense.
		Starting with her work in 1995 on the first bacterial genome to be sequenced, Dr. Fraser has become one of the most highly cited scientists in microbiology, and is an international leader in the field of microbial genomics and forensics.
	www.tigr.org (492 words)

	Scientists decipher genome of bacterium that remediates uranium contamination, generates electricity
		The genome sequence is now serving as the basis for detailed investigations, supported by the Department's Genomes to Life program, into the ability of Geobacter to reduce radionuclides and metals and to generate electricity.
		One of the surprises from the G. sulfurreducens genome was the high percentage of its genes devoted to sensing environmental conditions and then regulating its metabolism in response to changes in the environment.
		The Institute for Genomic Research (TIGR) is a not-for-profit research institute based in Rockville, Maryland.
	www.eurekalert.org /pub_releases/2003-12/tifg-sdg120803.php (1053 words)

	Deadly parasites show common genetic core
		El-Sayed is a molecular biologist at The Institute for Genomic Research (TIGR), of Rockville, Maryland, which conducted the genome sequencing and analysis along with scientists at the Wellcome Trust Sanger Institute in Hinxton, U.K.; the Seattle Biomedical Research Institute (SBRI); and the Karolinska Institutet, in Stockholm, Sweden.
		The Science issue includes several papers, including genome studies of Trypanosoma cruzi, which causes Chagas disease; Trypanosoma brucei, which causes African trypanosomiasis, also known as sleeping sickness; and Leishmania major, which causes the skin disease leishmaniasis and an internal disease known as kala azar.
		The Institute for Genomic Research (TIGR), which sequenced the first complete genome of a free-living organism in 1995, is a not-for-profit research institute based in Rockville, Maryland.
	www.eurekalert.org /pub_releases/2005-07/tifg-dps070805.php (684 words)

	USATODAY.com - Va. Tech partners with genomic research institute (Site not responding. Last check: 2007-10-13)
		The university and The Institute of Genomic Research of Rockville, Md., are teaming up to study microbial, plant and animal genomics, along with functional genomics, which have medical, agriculture and biodefense applications.
		Genomics is a branch of biotechnology that applies genetics and molecular biology in mapping and sequencing organisms' DNA and genes, organizing the results in databases and applying the information in medical or biological uses.
		TIGR also operates two centers under contract with the National Institute of Allergy and Infectious Diseases and a Bioinformatics Resource Center, one of eight such facilities that study pathogens that are considered biological threats or are associated with emerging or re-emerging infectious diseases.
	usatoday.com /tech/science/genetics/2004-11-08-va-tech-genomics_x.htm (601 words)

	ScienceDaily: Dog Genome Published By Researchers At TIGR, TCAG
		Researchers at The Institute for Genomic Research (TIGR) and The Center for the Advancement of Genomics (TCAG) have sequenced and analyzed 1.5X coverage of the dog genome.
		The research, published in the September 26th issue of the journal Science, asserts that a new method of genomic sequencing, partial shotgun sequencing, is a cost-effective and efficient method to sequence and analyze many more large eukaryotic genomes now that there are a number of reference genomes available with which to compare.
		Comparing the dog sequence data with current drafts of the human and mouse genome sequences showed that the dog lineage was the first to diverge from the common ancestor of the three species and that the human and dog are much more similar to each other at the genetic level than to the mouse.
	www.sciencedaily.com /releases/2003/09/030929060015.htm (1781 words)

	Research: TIGR
		The Institute for Genomic Research (TIGR) is a nonprofit research institute with interests in structural, functional, and comparative analysis of genomics and gene products in viruses, eubacteria, pathogenic bacteria, archea, and eukaryotes, including humans.
		The Institute first attained international acclaim when in 1995 TIGR scientists reported the completed sequence of the genome for the human pathogen Haemophilus influenzae.
		The data from TIGR's research effort is used by researchers from around the world in the quest to conquer disease and hunger.
	www.gwumc.edu /immunology/research/tigr.htm (172 words)

	ScienceDaily: Genome Of Potential Bioterror Agent Seqenced; Highlights Similarities Between Animal, Plant Pathogens
		The Walter Reed Army Institute of Research, which is the largest, most diverse, and oldest laboratory in the U.S. Army Medical Research and Materiel Command, conducts research on a range of militarily relevant issues, including naturally occurring infectious diseases, combat casualty care, operational health hazards, and medical defense against biological and chemical weapons.
		Researchers Unravel Anthrax Genomes (May 10, 2002) -- Researchers report the genetic comparison of two important isolates of the anthrax bacterium: the well-known Ames strain and an isolate from the recent Florida anthrax attacks.
		Researchers Improve Detection Of Diverse Anthrax Strains (August 31, 2004) -- Scientists have capitalized on genomic data to define novel diagnostic tests and to gain insight into the evolutionary and genetic history of the deadly pathogen Bacillus anthracis...
	www.sciencedaily.com /releases/2002/09/020924072147.htm (1945 words)

	International Research Team Announces Finished Rice Genome
		It's certainly not to researchers at The Institute for Genomic Research (TIGR), who have been sequencing the first food crop genome as part of an international consortium for the last six years.
		In the current study, researchers compared rice to the only other fully sequenced plant genome: Arabidopsis thaliana, a leafy plant that is a popular laboratory model.
		The new rice genome, pulled together by researchers worldwide under the umbrella of the International Rice Genome Sequencing Project, was completed three years ahead of schedule.
	www.monsanto.co.uk /news/ukshowlib.phtml?uid=9249 (711 words)

	Microbial Sequencing Centers, Division of Microbiology and Infectious Diseases, NIAID
		The National Institute of Allergy and Infectious Diseases (NIAID) recognizes the importance of microbial genomic research and has made a significant investment in the large-scale sequencing of genomes of human pathogens and invertebrate vectors of infectious diseases.
		Genomes that can be sequenced through these resources include microorganisms considered agents of bioterrorism (Categories A, B, and C), related organisms, clinical isolates, closely related species, and invertebrate vectors of disease and microorganisms responsible for emerging and re-emerging infectious diseases.
		Contracts for Microbial Genome Sequencing Centers have been awarded to The Institute for Genomic Research and the Massachusetts Institute of Technology.
	www.niaid.nih.gov /dmid/genomes/mscs/default.htm (447 words)

	The Institute for Genomic Research (TIGR) (Site not responding. Last check: 2007-10-13)
		TIGR is one of the original centers that conducted large-scale human genome sequencing on Chromosome 16 and is also one of two centers that conducted large-scale human BAC end sequencing, having generated >300,000 high quality end sequences from >186,000 human BACs for a total of 153 Mbp of human DNA sequence (1-3).
		One example of such collaboration is a project involving TIGR scientists and their colleagues at the International Livestock Research Institute (ILRI) in Nairobi, Kenya, on the sequence determination of the genome of a parasite that causes East Coast Fever, a fatal disease of cattle in sub-Saharan Africa.
		The Institute is currently under the direction of Claire M. Fraser, PhD who was elected President and Director of The Institute for Genomic Research in September 1998.
	www.acor.org /drugs/pipeline/companies/1539.profile (613 words)

	The Institute for Genomic Research Selects Sun Servers
		Sun Microsystems Inc. has announced that The Institute for Genomic Research (TIGR) selected Sun Microsystems to replace 15 HP Alpha servers and consolidate IT operations onto three Sun Fire x64 (x86, 64-bit) servers to power its complex genomic assembler for molecular research.
		Genome assembly is a computationally-intensive process of re-building a large number of short DNA sequences generated by a sequencing project.
		The group is responsible for manually finishing genomes and for providing laboratory services such as DNA library construction, sequencing, and research and development.
	www.hpcwire.com /hpc/834191.html (516 words)

	Genome Projects - The Institute for Genomic Research
		TIGR's Genome Projects are a collection of curated databases containing DNA and protein sequence, gene expression, cellular role, protein family, and taxonomic data for microbes, plants and humans.
		View predicted operons in completed microbial genomes based on conserved gene clusters.
		Integrating data from international EST sequencing and gene research projects, the Gene Indices are an analysis of the transcribed sequences represented in the world's public EST data.
	www.tigr.org /tdb (391 words)

	Genome Map
		Genome maps help scientists find their way around in an organism's genome -- all of its genetic material.
		These maps are not nearly as detailed as a road map, or a genome sequence with its thousands to billions of letters, but they can aid scientists by pointing out areas for further exploration.
		Some parts of a genome map may be very detailed and complete, while other areas are relatively uncharted.
	www.ocean.udel.edu /extreme2004/genomics/genomemap.html (202 words)

	Research Institute Posts Gene Data on Internet
		The Institute for Genomic Research, a not-for-profit group, released the highly complicated scientific data Tuesday on a Web site set up on conjunction with the National Center for Biotechnology Information at the National Institutes of Health.
		The institute was the first to determine the entire genetic sequence of a living organism, unveiling in 1995 the genetic code for a bacterium that causes a type of meningitis.
		Human Genome had financed part of the institute's work in return for the right to study its findings before they were made public.
	partners.nytimes.com /library/cyber/week/062697gene.html (414 words)

	Genomic Medicine Institute
		The Genomic Medicine Institute (GMI) will serve as the expert base for the principles and practice of genomic medicine by being a single platform for scholarly activity (research), academic clinical care and outreach/education ultimately directed at genomics-based personalized healthcare.
		Thus, GMI research will focus on translational and clinical human genetics and genomics (broadly defined to include epigenetics and proteomics as well) which would be eminently applicable to the routine clinical arena.
		The GMI is a new institute directed by Charis Eng, M.D., Ph.D., and will be housed in the new Center for Genomics Research building’s fifth floor, which is specifically designed to enhance translational genomics.
	www.lerner.ccf.org /gmi (307 words)

	The Institute for Genomic Research (Site not responding. Last check: 2007-10-13)
		The Institute for Genomic Research (TIGR) is a non-profit organization dedicated to deciphering and analyzing genomes—the complex molecular chains that constitute each organism’s unique genetic heritage.
		In 1995, TIGR helped launch the genome era with its landmark publication of the first full DNA sequence of a free-living organism, the bacterium Haemophilus influenzae, and followed up that achievement with a series of scientific accomplishments that have advanced a number of scientific fields.
		Genomic research is a compute-intensive pursuit, and requires both hardware and software capable of handling sequencing queries that run to billions of simultaneous calculations.
	www.sun.com /customers/servers/tigr.xml (834 words)

	Small is Bountiful: TIGR's Claire M. Fraser on Microbial Genomes
		Since The Institute for Genomic Research (TIGR) in Rockville, Maryland, first published the sequence of Haemophilus influenzae in 1995, nearly 60 fully sequenced microbial genomes have been published, and well over 100 more are in the works.
		After a one-year postdoc at SUNY Buffalo, Fraser moved on to the Roswell Park Cancer Institute and then spent eight years at the National Institutes of Health (NIH), where she was named chief of the Section of Molecular Neurobiology at the National Institute of Alcohol Abuse and Alcoholism in 1989.
		At NIH, the National Institute of Allergy and Infectious Diseases and the National Institute of Dental and Craniofacial Research have both targeted key human pathogens, and DOE has been interested in organisms of environmental relevance, either because they represent extremophiles or because they have potential for bio-remediation.
	www.sciencewatch.com /jan-feb2002/sw_jan-feb2002_page3.htm (1004 words)

	Sun Microsystems - South Africa - Institute for Genomic Research chooses Sun Microsystems
		The institute will be using the servers to conduct complex molecular research and can achieve this with improved energy efficiency, reliability and performance thanks to the Sun Fire servers.
		The institute selected the Sun Fire x64 servers, a range of 64-bit x86 servers from Sun for customers who have different needs from what is catered for by Sun’s SPARC architecture.
		The Institute for Genomic Research is a non-profit research institute based in Rockville, Maryland, USA.
	za.sun.com /sunnews/press/2006/060909.html (485 words)

	GSC: Home
		The Genome Sequencing Center is a world-leader in the generation and public dissemination of high-quality genomic sequence.
		The Genome Sequencing Center at Washington University School of Medicine announces the release of over 400,000 primer sequences to facilitate the amplification and re-sequencing of human genes.
		The Genome Sequencing Center has been chosen as the lead institution for a project, jointly sponsored by the National Science Foundation, the U. Department of Energy, and the U. Department of Agriculture, to sequence the maize genome.
	genome.wustl.edu (385 words)

	News - Companies - USA - The Institute for Genomic Research
		The Institute for Genomic Research collaborates with Universities of California, Minnesota, Wisconsin and Cornell on potato disease project
		The Institute for Genomic Research is a not-for-profit research institute with interests in structural, functional, and comparative analysis of genomes and gene products in viruses, eubacteria, pathogenic bacteria, archaea, and eukaryotes (both plant and animal), including humans.
		The Institute is located in Rockville, MD, in the greater Washington, D.C. metropolitan area, and is close to the National Institutes of Health, Johns Hopkins University, The University of Maryland, and other research institutes and biotechnology companies.
	www.seedquest.com /News/Companies/USA/tigr.htm (286 words)

	The Institute for Genomic Research (TIGR), J. Craig Venter Institute, J. Craig Venter Science Foundation Consolidate ...
		Research Organization Formerly Known as Venter Institute is Renamed The Center for the Advancement of Genomics (TCAG) Claire Fraser-Liggett, Ph.D., is TIGR Division President, Robert Strausberg, Ph.D., is Named President of TCAG Division ROCKVILLE, Md., Oct. 16 /PRNewswire/ -- The Boards of Directors of the J.
		Craig Venter Institute (JCVI), The Institute of Genomic Research (TIGR) and the J. Craig Venter Science Foundation (JCVSF) today announced the consolidation of these affiliated organizations into one organization, the J.
		The research organization formerly known as JCVI will be renamed The Center for the Advancement of Genomics (TCAG).
	www.prnewswire.com /cgi-bin/stories.pl?ACCT=104&STORY=/www/story/10-16-2006/0004452388&EDATE= (449 words)

	AAAS Annual Meeting - MPE - SEMINARS
		The completion of a draft sequence of the human genome has heightened awareness of the importance and vast potentials for benefit from genomic studies.
		Research in the next 50 years promises another transformation as the electron is replaced by the light, in the form of photons, as a carrier of information.
		The key to achieving this is are photonic crystals, which allow high control of confinement and propagation of light at very small dimensions, enabling design and integration of a wide array of optical nanodevices on a single chip.
	www.aaas.org /meetings/2002/MPE_04.shtml (502 words)

	genome.gov \| National Human Genome Research Institute
		Two leaders in the medical application of basic research - Dr. Leslie Biesecker and Dr. David Bodine - are the new branch chiefs for the Genetic Disease Research Branch and the Genetics and Molecular Biology Branch, respectively.
		NHGRI conducts genetic and genomic clinical research on diseases from lung and colon cancer, to diabetes, attention deficit hyperactivity disorder and Parkinson's.
		The National Human Genome Research Institute led the Human Genome Project for the National Institutes of Health, which culminated in the completion of the full human genome sequence in April 2003.
	www.genome.gov (283 words)

	The Institute for Genomic Research Osa1 Rice Genome Annotation Database -- Yuan et al. 138 (1): 18 -- PLANT PHYSIOLOGY
		The Institute for Genomic Research Osa1 Rice Genome Annotation Database -- Yuan et al.
		The Institute for Genomic Research, Rockville, Maryland 20850
		Barry GF (2001) The use of the Monsanto draft rice genome sequence in research.
	www.plantphysiol.org /cgi/content/full/138/1/18 (5173 words)

	Web Sites - Functional Microbial Genomics
		http://www.tigr.org/ - The Institute for Genomic Research is a not-for-profit research institute with interests in structural, functional, and comparative analysis of genomes and gene products in viruses, eubacteria, pathogenic bacteria, archaea, and eukaryotes (both plant andanimal), including humans.
		The Institute for Genomic Research [TIGR] Database is a collection of curated databases containing DNA and protein sequence, gene expression, cellular role, protein family, and taxonomic data for microbes, plants and humans.
		Kyoto Encyclopedia of Genes and Genomes (KEGG) is an effort to computerize current knowledge of molecular and cellular biology in terms of the information pathways that consist of interacting molecules or genes and to provide links from the gene catalogs produced by genome sequencing projects.
	www.geneseo.edu /~simon/genomics/genome_resources02.htm (601 words)

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