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Topic: Thioridazine

Related Topics

Trifluoperazine

Typical antipsychotic

Haloperidol

Chlorpromazine

Haloperidol

Fluphenazine

	Thioridazine - Wikipedia, the free encyclopedia
		Thioridazine is a piperidine phenothiazine antipsychotic drugs and is used in the treatment of schizophrenia and psychosis.
		Thioridazine is known to kill multidrug-resistant mycobacterium tuberculosis and MRSA at clinical concentrations..
		It is advisable to withdraw thioridazine gradually and not abruptly to avoid unpleasant withdrawal symptoms (agitation, insomnia, anxiety).
	en.wikipedia.org /wiki/Thioridazine (728 words)

	Thioridazine (Mellaril) Antipsychotics (Site not responding. Last check: 2007-08-08)
		Thioridazine also has been used to treat anxiety associated with major depression, dementia in the elderly, and severe behavioral problems in children.
		Thioridazine was approved by the FDA in 1959.
		Thioridazine is rapidly absorbed following oral administration, but there is considerable individual patient variation in peak plasma concentrations because the drug undergoes metabolism in the gastric mucosa and during first pass through the liver.
	www.rockford.uic.edu /jc/thiorida.htm (338 words)

	British Journal of Pharmacology - Pharmacokinetics and metabolism of thioridazine during co-administration of tricyclic ... (Site not responding. Last check: 2007-08-08)
		Thioridazine 5-sulphoxide (a ring sulphoxide) is not pharmacologically active at dopaminergic or noradrenergic receptors, but is considered to contribute to the cardiotoxicity of the parent compound (Gottschalk et al., 1978; Hale and Poklis, 1986).
		The kinetics of inhibition of thioridazine (THIOR) 2-sulphoxidation by imipramine (IMI) or amitriptyline (AMI) in vitro.
		The kinetics of inhibition of thioridazine (THIOR) 5-sulphoxidation by imipramine (IMI) or amitriptyline (AMI) in vitro.
	www.nature.com /bjp/journal/v131/n2/full/0703540a.html (5280 words)

	Thioridazine And Arrhythmia: Prescribing Changes
		Thioridazine therapy should be initiated only by a specialist and only after the patient has failed to respond adequately to treatment with appropriate courses of at least two other suitable medicines.
		It is recommended that the initial dose of thioridazine be at the lower end of the range and be gradually increased until the desired effect is achieved or a maximum of 200mg daily is reached.
		Abrupt withdrawal of thioridazine may be associated with symptoms such as nausea, vomiting, gastric upset, trembling, dizziness, anxiety, agitation and insomnia, as well as transient dyskinesia or the re-emergence of psychotic symptoms.
	www.medsafe.govt.nz /Profs/PUarticles/thioridazine.htm (1080 words)

	Thioridazine for dementia (Cochrane Review)
		Thioridazine, a phenothiazine neuroleptic, has been commonly prescribed because it was thought to produce relatively less frequent motor side effects.
		Thioridazine was also associated with significantly more dizziness.No superiority for thioridazine was shown in comparisons with etoperidone, loxapine or zuclopenthixol, except to produce fewer side effects than loxapine.
		If thioridazine were not currently in widespread clinical use, there would be inadequate evidence to support its introduction.The only positive effect of thioridazine when compared to placebo is the reduction of anxiety.
	www.update-software.com /abstracts/ab000464.htm (668 words)

	thioridazine Consumer Drug Information
		Thioridazine may interact with other drugs that cause drowsiness, including alcohol, antidepressants, antihistamines, pain relievers, anxiety medicines, seizure medicines, and muscle relaxants.
		Thioridazine is used to treat psychotic disorders, such as schizophrenia.
		Thioridazine is generally reserved for people who do not respond to other drugs or who cannot take other drugs due to side effects.
	www.drugs.com /MTM/thioridazine.html (1701 words)

	Thioridazine for schizophrenia (Cochrane Review) (Site not responding. Last check: 2007-08-08)
		Limited data from trials suggest that thioridazine is not strongly anticholinergic (blurred vision RR 2.01 CI 0.56-7.25, n=224).
		Thioridazine is not sedating (at three months to one year RR 2.48 CI 0.96-6.4, n=122).
		Thioridazine has been considered a drug of choice in the elderly with schizophrenia but this clinical preference does not appear to be based on good quality trial based evidence.
	www.cochrane.org /cochrane/revabstr/ab001944.htm (697 words)

	NOW Foods - Thioridazine
		Until more is known, people taking thioridazine should exercise caution with vitamin A supplementation and be alert for side effects such as bone pain, headaches, dry scaly skin, and hair loss.
		Lithium is a mineral that may be present in some supplements and is also used in large amounts to treat mood disorders such as bipolar disorder (manic depression).
		One uncontrolled study showed that 10 of 13 individuals experienced a reduction in disorganized thoughts, hallucinations, and suspicious thoughts when 8 grams of vitamin C was added to their daily drug therapy.
	www.nowfoods.com /?action=itemdetail&item_id=5454 (930 words)

	Thioridazine, Mellaril Pharmacology-HealthyPlace.com
		Thioridazine (Mellaril) is contraindicated in patients known to be hypersensitive to it.
		However, thioridazine has been shown to be helpful in the treatment of behavioral disorders in epileptic patients.
		Therefore, thioridazine should be used in women who are or might become pregnant only if the clinical condition clearly justifies potential risk to the fetus.
	www.healthyplace.com /medications/thioridazine.htm (1273 words)

	Thioridazine Indications (Site not responding. Last check: 2007-08-08)
		The antipsychotic action of thioridazine is of use mainly for the treatment of schizophrenia.
		Compared to many other neuroleptic agents, higher doses of thioridazine must be administered to achieve the desired effect.
		Thioridazine is also used for the treatment of autistic children and of epileptic children with behavioural disorders.
	www.infomed.org /100drugs/thioind.html (170 words)

	- Mellaril
		The slow hydroxylators obtained higher serum levels of thioridazine with a 2.4-fold higher Cmax and an 4.5-fold larger AUC associated with a twofold longer half-life compared with that of the rapid hydroxylators.
		Since the degree of QTc interval prolongation appears to be related to the dose of thioridazine, it is reasonable to assume that concomitant medications or other factors which produce elevations in thioridazine plasma levels will increase the degree of QTc prolongation and possibly increase the risk of serious ventricular arrhythmias.
		Plasma levels of thioridazine and metabolites are influenced by the debrisoquin hydroxylation phenotype.
	www.fda.gov /medwatch/safety/2000/mellar.htm (1009 words)

	Health Library -
		Thioridazine is used to treat symptoms associated with psychosis; depression with worry and restlessness in adults; irritability, worry, and fear in elderly; and severe behavioral problems in children, including fighting and hyperactivity.
		In a controlled study, individuals taking thioridazine for psychosis cooperated better and withdrew less from other people when niacin, 300-1,500 mg each day, was added.
		Controlled studies are needed to determine whether women taking thioridazine, who are experiencing menstrual changes, might benefit from supplemental vitamin C. Vitamin C might also enhance the effectiveness of neuroleptic drugs, such as thioridazine, in the treatment of schizophrenia.
	myhealth.ucsd.edu /library/healthguide/en-us/Cam/topic.asp?hwid=hn-1518005 (843 words)

	Thioridazine for schizophrenia (Site not responding. Last check: 2007-08-08)
		Thioridazine is a piperidine phenothiazine used for the treatment of people with schizophrenia.
		To examine the effects of thioridazine for those with schizophrenia, and, in particular, elderly people with schizophrenia.
		Although there are shortcomings and gaps in the data, there appears to be enough consistency over different outcomes and periods to confirm that thioridazine is an antipsychotic of similar efficacy to other commonly used neuroleptics for people with schizophrenia.
	www.cochrane.org /reviews/english/ab001944.html (663 words)

	Thioridazine for dementia (Site not responding. Last check: 2007-08-08)
		Thioridazine has significant sedative effect, and it is thought that this is the main mechanism of action in calming and controlling the patient.
		Thioridazine has minimal or no effect on global ratings, while other drugs such as chlormethiazole are superior to it on behavioural ratings.
		Unconfounded, single-blind or double-blind, randomised trials were identified in which treatment with thioridazine was administered for more than one dose and compared to an alternative intervention in patients with dementia of any aetiology.
	www.cochrane.org /reviews/english/ab000464.html (750 words)

	Thioridazine - Patient UK
		Thioridazine is effective in helping symptoms such as hearing voices, loss of energy, thought disturbances and difficulties communicating with others as well as other symptoms of schizophrenia.
		Make sure you know how Thioridazine affects you before driving, operating machinery, or doing other jobs that could be dangerous if you were not fully alert or able to see well.
		Thioridazine may cause you to sweat less, causing your body temperature to increase.
	www.patient.co.uk /showdoc/30002970 (918 words)

	Thioridazine
		Thioridazine does not mix well with many medicines.
		If you have an allergy to thioridazine or any other part of the medicine.
		Thioridazine changes a variety of chemicals in the brain.
	www.umm.edu /altmed/ConsDrugs/Thioridazinecd.html (842 words)

	MedlinePlus Drug Information: Thioridazine
		Thioridazine is used to treat schizophrenia and symptoms such as hallucinations, delusions, and hostility.
		Thioridazine comes as a tablet, liquid suspension, and liquid concentrate to take by mouth.
		If you take thioridazine once a day at bedtime and do not remember it until the next morning, omit the missed dose.
	www.nlm.nih.gov /medlineplus/druginfo/medmaster/a682119.html (868 words)

	Effect of thioridazine on phenytoin serum concentration: a retrospective study -- Sands et al. 21 (3): 267 -- The ...
		Effect of thioridazine on phenytoin serum concentration: a retrospective study -- Sands et al.
		Serum phenytoin concentrations before and after the addition of thioridazine were retrospectively compared in 27 adults to determine if an interaction occurred between these two drugs.
		Clinically important alterations in phenytoin serum concentration as caused by thioridazine appear to be infrequent.
	www.theannals.com /cgi/content/abstract/21/3/267 (166 words)

	Thioridazine (Site not responding. Last check: 2007-08-08)
		Thioridazine is used to treat symptoms associated with psychosis;
		An animal study found that the effects of chlorpromazine, a drug similar to (perphenazine, prochlorperazine, thioridazine), were enhanced when a bacopa extract was given along with it.
		Until more is known, people taking medications from this family of drugs (called phenothiazines) should not take bacopa.
	www.a1nutritionproducts.com /health/Drug/Thioridazine.htm (927 words)

	Thioridazine and sudden unexplained death in psychiatric in-patients -- REILLY et al. 180 (6): 515 -- The British ...
		Thioridazine and sudden unexplained death in psychiatric in-patients -- REILLY et al.
		Thioridazine and sudden unexplained death in psychiatric in-patients
		of thioridazine is further justified by this study.
	bjp.rcpsych.org /cgi/content/full/180/6/515 (3532 words)

	Cardiac arrest and ventricular arrhythmia in patients taking antipsychotic drugs: cohort study using administrative ... (Site not responding. Last check: 2007-08-08)
		Although QT prolongation is used as a marker of arrhythmogenicity, it is unknown whether thioridazine is any worse than haloperidol with regard to cardiac safety
		Thioridazine may carry a greater risk than haloperidol at high doses
		Patients should be treated with the lowest dose of thioridazine needed to treat their symptoms
	bmj.bmjjournals.com /cgi/content/abstract/325/7372/1070 (371 words)

	Thioridazine And Retrograde Ejaculation (Site not responding. Last check: 2007-08-08)
		Due to the presence of persistent sleep disturbance, the haloperidol was replaced with thioridazine (200 mg/day).
		Within a fortnight of commencement of thioridazine, J returned with the complaints of impaired sexual functioning.
		He requested that the thioridazine be stopped and the haloperidol resumed.
	www.indegene.com /Psy/ClinRound/indPsyCase14.html (320 words)

	Mellaril, Thioridazine hydrochloride, side effects, drug interactions, overdose, dosage
		If you are taking Mellaril in a liquid concentrate form, you can dilute it with a liquid such as distilled water, soft tap water, or juice just before taking it.
		Do not change from one brand of thioridazine to another without consulting your doctor.
		Agitation, blurred vision, coma, confusion, constipation, difficulty breathing, dilated or constricted pupils, diminished flow of urine, dry mouth, dry skin, excessively high or low body temperature, extremely low blood pressure, fluid in the lungs, heart abnormalities, inability to urinate, intestinal blockage, nasal congestion, restlessness, sedation, seizures, shock
	www.pdrhealth.com /drug_info/rxdrugprofiles/drugs/mel1253.shtml (925 words)

	Thioridazine (Site not responding. Last check: 2007-08-08)
		Pick a Thioridazine because it to canary the man with her.
		Fertilitys dream, and bard a Thioridazine claimed the smell of Thioridazine disorders,i.
		Pyromaniac, according to side of plaster dust to an Thioridazine.
	drug-overdose.net /mad/Thioridazine (298 words)

	Health Library - (Site not responding. Last check: 2007-08-08)
		Thioridazine is available with a prescription under the brand name Mellaril.
		Other brand or generic formulations may also be available.
		Healthwise disclaims any liability for the decisions you make based on this information.
	yalenewhavenhealth.org /library/healthguide/en-us/drugguide/topic.asp?hwid=d00389a1 (1784 words)

	Thioridazine - Thioridazine Side Effects - Thioridazine Information - Canada Pharmacy - Canada Drugs (Site not responding. Last check: 2007-08-08)
		Nonmedicinal ingredients: carnauba wax, D&C Yellow #10 aluminum lake, hydroxypropyl methylcellulose, FD&C Blue #2 aluminum lake, magnesium stearate, microcrystalline cellulose, polyethylene glycol 3350 and titanium dioxide.
		Nonmedicinal ingredients: carnauba wax, ferric-ferrous oxide, hydroxypropyl methylcellulose, magnesium stearate, microcrystalline cellulose, polyethylene glycol 3350, red ferric oxide, titanium dioxide and yellow ferric oxide.
		Nonmedicinal ingredients: carnauba wax, D&C Yellow #10 aluminum lake, ferric-ferrous oxide, hydroxypropyl methylcellulose, FD&C Blue #2 aluminum lake, magnesium stearate, microcrystalline cellulose, polyethylene glycol 3350 and titanium dioxide.
	www.rxcarecanada.com /Thioridazine.asp?prodid=1692 (328 words)

	Search Results for thioridazine - Encyclopædia Britannica (Site not responding. Last check: 2007-08-08)
		Features the pharmacology, usage, toxicity, side effects, and dosage of this drug.
		Facts on the usage and the side effects of thioridazine hydrochloride used to treat mild depression and anxiety.
		Mentions the usage, the precautions necessary during medication, and the consequences of an overdose.
	www.britannica.com /search?query=thioridazine&submit=Find&source=MWTEXT (136 words)

	Mellaril / Thioridazine Hydrochloride Lawsuit News Article - Mellaril Linked to Sudden Unexplained Deaths - Find Trial ...
		If you or a family member has been injured, contact a personal injury attorney today.
		According to a new report in this month's issue of the British Journal of Psychiatry, researchers have linked Mellaril, also known as Thioridazine Hydrochloride, to several unexplained deaths in England.
		Dr. Simon H. Thomas and colleagues from the University of Newcastle studied several cases of unexplained death among psychiatric in-patients, determining that Mellaril-induced torsades de pointes arrhythmia may be the cause.
	www.injuryboard.com /view.cfm/Article=1536 (273 words)

	Thioridazine - Find Thioridazine Suppliers, Thioridazine Manufacturers and Thioridazine Distributors
		Power Sourcing is your best source for finding thioridazine suppliers.
		Use our expansive directory to source suppliers of thioridazine and to source other products and services from thousands of suppliers, manufacturers, and distributors.
		These are just a few of our thioridazine suppliers.
	www.powersourcing.com /se/thioridazine.htm (130 words)

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