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Topic: Thymine


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RNA

In the News (Sun 17 Dec 17)

  
  thymine — FactMonster.com
Thymine was the first pyrimidine to be purified from a natural source, having been isolated from calf thymus and beef spleen in 1893–4.
The accepted structure of the thymine molecule was published in 1900; this structure was confirmed when several investigators reported the synthesis of the compound during the period 1901 to 1910.
The analogous nucleosides and nucleotides formed from thymine and ribose occur only very rarely in living systems; such is not the case with the other pyrimidines.
www.factmonster.com /ce6/sci/A0848663.html   (290 words)

  
  Thymine - Wikipedia, the free encyclopedia
Thymine is found in the nucleic acid DNA.
Thymine combined with deoxyribose creates the nucleoside deoxythymidine, which is synonymous with the term thymidine.
One of the common mutations of DNA involves two adjacent thymines or cytosine, which in presence of ultra violet light may form pyrimidine dimers, causing "kinks" in the DNA molecule that inhibit normal function.
en.wikipedia.org /wiki/Thymine   (170 words)

  
 thymine. The Columbia Encyclopedia, Sixth Edition. 2001-05   (Site not responding. Last check: 2007-10-30)
Thymine was the first pyrimidine to be purified from a natural source, having been isolated from calf thymus and beef spleen in 1893–4.
The accepted structure of the thymine molecule was published in 1900; this structure was confirmed when several investigators reported the synthesis of the compound during the period 1901 to 1910.
Combined with the sugar deoxyribose in a glycosidic linkage, thymine forms a derivative called thymidine (a nucleoside), which in turn can be phosphorylated with from one to three phosphoric acid groups, yielding respectively the three nucleotides TMP (thymidine monophosphate), TDP (thymidine diphosphate), and TTP (thymidine triphosphate).
www.bartleby.com /65/th/thymine.html   (274 words)

  
 The Individualist: Thymine
As the name implies, thymine may be derived by methylation of uracil at the 5th carbon.
Thymine combined with deoxyribose creates the nucleoside deoxythymidine, which is synonymous with the term thymidine.
One of the common mutations of DNA involves two adjacent thymines or cytosine, which in presence of ultraviolet light may form pyrimidine dimers, causing "kinks" in the DNA molecule that inhibit normal function.
www.dadamo.com /wiki/wiki.pl/Thymine   (264 words)

  
 Characterization of the effects of a thymine glycol residue on the structure, dynamics, and stability of duplex DNA by ...
Characterization of the effects of a thymine glycol residue on the structure, dynamics, and stability of duplex DNA by NMR -- Kao et al.
Characterization of the effects of a thymine glycol residue on the structure, dynamics, and stability of duplex DNA by NMR
The presence of thymine glycol lowers the thermal stability of duplex DNA.
www.jbc.org /cgi/content/abstract/268/24/17787   (578 words)

  
 Re: Why does uracil replace thymine in RNA?
As you already know, the difference between RNA (ribonucleic acids) and DNA (deoxyribonucleic acids) is the existence of a hydroxyl (-OH) group on the 2' carbon of the ribose sugar in the backbone.
To sum up: the replacement of thymine for uracil in DNA protects the DNA from attack and maintains the fidelity of DNA replication.
Since Thymine is basically methyl-U, the cell's DNA repair mechanisms can distinguish illegitimate U from legitimate methyl-U in DNA, and make the proper repair (replacing any U with a C).
www.madsci.org /posts/archives/dec97/879354206.Bc.r.html   (593 words)

  
 thymine - OneLook Dictionary Search
thymine : Compact Oxford English Dictionary [home, info]
Thymine (T) : MedTerms.com Medical Dictionary [home, info]
Phrases that include thymine: thymine deoxyribonucleoside, hypoxanthine aminopterin thymine medium, thymine deoxyribonucleotide, thymine 2-oxoglutarate dioxygenase, thymine d, more...
www.onelook.com /?w=thymine   (234 words)

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