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Topic: Thyroid stimulating hormone


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In the News (Sun 20 Dec 09)

  
  Hormones of the Pituitary
stimulated by the arrival of thyrotropin releasing hormone (TRH) from the hypothalamus.
Synthesis and release of FSH is triggered by the arrival from the hypothalamus of gonadotropin-releasing hormone (GnRH).
The GH-secreting cells are stimulated to synthesize and release GH by the intermittent arrival of growth hormone releasing hormone (GHRH) from the hypothalamus.
users.rcn.com /jkimball.ma.ultranet/BiologyPages/P/Pituitary.html   (1333 words)

  
 The Thyroid Gland: A General Introduction | thyroid disease | goitre | goiter | | iodine | hormones
The thyroid gland is located in the front of the neck attached to the lower part of the voicebox (or larynx) and to the upper part of the windpipe (or trachea).
Abnormalities of the thyroid gland are common and affect one in twenty (1 in 20) of the Canadian population.
In Hashimoto's thyroiditis, the goitre is caused by an accumulation of white blood cells and fluid (inflammation) in the thyroid gland.
www.thyroid.ca /Guides/HG01.html   (987 words)

  
 Thyroid-Stimulating Hormone (TSH)
TSH is produced when the hypothalamus releases a substance called thyrotropin-releasing hormone (TRH).
TSH levels can help determine whether hypothyroidism is due to a damaged thyroid gland or some other cause (such as a problem with the pituitary gland or the hypothalamus).
TSH levels that do not rise after the injection can indicate the presence of conditions such as a damaged pituitary gland (secondary hypothyroidism), Graves' disease, or any condition that causes an overactive thyroid gland (hyperthyroidism).
my.webmd.com /hw/health_guide_atoz/hw28656.asp   (1084 words)

  
 Thyroid-stimulating hormone - Freepedia   (Site not responding. Last check: 2007-11-05)
Thyroid-stimulating hormone (also known as TSH or thyrotropin) is a hormone produced by thyrotropes in the anterior pituitary gland which controls the endocrine function of the thyroid gland.
TSH stimulates the thyroid gland to secrete the hormones thyroxine (T4) and triiodothyronine (T3).
The thyroid-stimulating hormone test measures the amount of TSH in the blood, to see if the thyroid gland is overactive or underactive.
en.freepedia.org /TSH.html   (142 words)

  
 Hypothyroidism — Diagnosis   (Site not responding. Last check: 2007-11-05)
The TSH measurement is of fundamental importance since it reflects the sufficiency of the brain’s supply of thyroid hormone.
A normal range TSH indicates that the hypothalamus senses a normal amount of thyroid hormone and is stimulating the thyroid to continue making and releasing thyroid hormone at the same rate.
TSH measurement may help the physician to determine if the problem is primary (thyroid gland) or secondary (pituitary gland) hypothyroidism.
www.armourthyroid.com /hypothyroidism/diagnosis.html   (813 words)

  
 Thyroid Deficiency: Online Reference For Health Concerns
Hashimoto's thyroiditis is the most common form of hypothyroidism, presenting with an enlarged thyroid gland that becomes nonfunctional, with the active parts of the gland deteriorating after several years.
Even when all other hormones are normal, a low level of trans-thyretrin could mean that you are not producing enough thyroid hormones and that it is not being delivered to the cells.
The patient's level of TSH is measured through a blood test, then the patient is given an injection of TRH (a harmless synthetic hormone, modeled after the TRH secreted by the hypothalamus gland in the brain); 25 minutes later blood is drawn and the TSH is measured again.
www.lef.org /protocols/prtcl-104.shtml   (2148 words)

  
 AllRefer Health - TSH (Thyroid Stimulating Hormone, Thyrotropin) - Test/Medical Exams/Tests
TSH is measured as a screening test for abnormal thyroid function.
TRH, a hormone produced in the hypothalamus, stimulates the pituitary gland to release TSH.
TSH subsequently stimulates the thyroid to produce thyroid hormone, T3 and T4.
health.allrefer.com /health/tsh-info.html   (343 words)

  
 Rethinking the TSH Test: An Interview with David Derry, M.D., Ph.D.
The History of Thyroid Testing, Why the TSH Test ...
The main ingredient of thyroid hormone, which distinguishes it from other molecules of similar size (molecular size), was the element which made thyroid hormone namely iodine.
However as the TSH was so sensitive to orally-given thyroid hormone it meant literally everyone was going to end up with a low dose by comparison with previous doses.
David Derry: For many years the literature (before the TSH) supported the fact that if your symptoms responded to thyroid hormone you were low thyroid but especially if when you took the person off the thyroid and their symptoms returned.
www.thyroid-info.com /articles/david-derry.htm   (4245 words)

  
 Thyroid Stimulating Hormone
It is similar to the alpha subunit of follicle-stimulating hormone, luteinizing hormone and human chorionic gonadotropin.
TSH binds with membrane bound TSH receptors on the cells of the thyroid gland.
TSH also increases the transcription of mRNA for thyroglobulin and thyroidal peroxidase (TPO), and increases the formation and activity of lysosomes which will hydrolyze the iodinated thyroglobulin to form thyroid hormones.
macromolonline.8m.com /endo/hormones/tsh.htm   (486 words)

  
 TSH: The Test
TSH screening is routinely performed in the United States on newborns as part of each state’s newborn screening program.
A high TSH result often means an underactive thyroid gland that is not responding adequately to the stimulation of TSH due to some type of acute or chronic thyroid dysfunction.
A high TSH value can also occur when patients with a known thyroid disorder (or those who have had their thyroid gland removed) are receiving too little thyroid hormone medication.
www.labtestsonline.org /understanding/analytes/tsh/test.html   (629 words)

  
 Thyroid-Stimulating Hormone   (Site not responding. Last check: 2007-11-05)
Thyroid-stimulating hormone, also known as thyrotropin, is secreted from cells in the anterior pituitary called thyrotrophs, finds its receptors on epithelial cells in the thyroid gland, and stimulates that gland to synthesize and release thyroid hormones.
TSH is a glycoprotein hormone composed of two subunits which are non-covalently bound to one another.
The alpha subunit of TSH is also present in two other pituitary glycoprotein hormones, follicle-stimulating hormone and luteinizing hormone, and, in primates, in the placental hormone chorionic gonadotropin.
arbl.cvmbs.colostate.edu /hbooks/pathphys/endocrine/hypopit/tsh.html   (239 words)

  
 The Kelly G. Ripken Program - Free Thyroid Screening
Almost all patients with an underactive thyroid (hypothyroidism) or overactive thyroid (hyperthyroidism) can be diagnosed with a simple blood test, thyroid stimulating hormone, TSH.
The pituitary gland in the brain monitors the levels of thyroid hormone in the bloodstream.
TSH is released from the pituitary and stimulates the thyroid gland to liberate thyroid hormones.
thyroid-ripken.med.jhu.edu /testing   (104 words)

  
 TSH Test (Thyroid Stimulating Hormone)
Thyroid hormones control metabolism and organ function, directly affecting weight loss or gain, energy levels, skin condition, memory, heart rate, cholesterol levels, menstrual regularity, memory as well as many other functions.
TSH (thyroid stimulating hormone) is a chemical substance produced by the pituitary gland that stimulates the thyroid gland to synthesize and release its own hormones into the bloodstream.
When not enough thyroid hormone is produced, a condition called hypothyroidism will result, often referred to as an underactive thyroid.
www.healthworks2000.com /THSTest.htm   (1549 words)

  
 THYROID STIMULATING HORMONE   (Site not responding. Last check: 2007-11-05)
Thyroid (thi-roid) stimulating hormone (TSH) is found in the blood.
TSH can be measured in your blood by a special laboratory test to see how your thyroid gland is working.
TSH may be the best single test to see if your thyroid gland is working OK. Sometimes it may be necessary to do other thyroid tests at the same time as the TSH.
www.medformation.com /ac/mm_qdis.nsf/qd/nd7014g.htm   (510 words)

  
 Hormone, thyroid stimulating (TSH) definition - Thyroid: health and medical information about Thyroid Disease, ...
Hormone, thyroid stimulating (TSH): A hormone produced by the pituitary gland at the base of the brain in response to signals from the hypothalamus gland in the brain.
TSH promotes the growth of the thyroid gland in the neck and stimulates it to produce more thyroid hormones.
Thyroid stimulating hormone is also known as thyrotropin.
www.medterms.com /script/main/art.asp?articlekey=3800   (218 words)

  
 Thyroid-stimulating Hormone Levels in Children from Chernobyl
A working hypothesis is proposed by which the shift in TSH levels in girls from high radiocontamination areas was associated with subclinical radiation damage from environmental radioiodine at the time of the accident.
This preliminary study assesses thyroid function in immigrants who were children (0 to 16 years of age) at the time of the Chernobyl accident and reports on preliminary results of assessments of thyroid-stimulating hormone (TSH) serum levels in these young people.
Hence, elevated TSH in a population group could be a marker for prior exposure of the thyroid to environmental radioiodine.
ehp.niehs.nih.gov /members/1997/Suppl-6/quastel-full.html   (1428 words)

  
 Adult Health Advisor 2005.2: Thyroid-Stimulating Hormone (TSH) Test
When your thyroid gland is underactive and not producing enough thyroid hormone, your body produces more TSH to stimulate the gland and increase its activity.
When your thyroid gland is overactive and producing too much thyroid hormone, your body decreases the amount of TSH to slow production of thyroid hormone.
You had an overactive thyroid gland that was removed or destroyed and you are not taking enough replacement thyroid hormone.
www.med.umich.edu /1libr/aha/aha_thystiho_crs.htm   (608 words)

  
 How Your Thyroid Works
Your thyroid gland is a small gland, normally weighing less than one ounce, located in the front of the neck.
During development (inside the womb) the thyroid gland originates in the back of the tongue, but it normally migrates to the front of the neck before birth.
Thyroid cells are the only cells in the body which can absorb iodine.
www.endocrineweb.com /thyfunction.html   (473 words)

  
 THYROID STIMULATING HORMONE   (Site not responding. Last check: 2007-11-05)
A hormone which is secreted by the anterior pituitary gland.
Thyroid stimulating hormone (TSH) stimulates the thyroid to produce more thyroid hormones (T4 and T3).
T4 and T3 blood levels feedback on the pituitary gland and decrease TSH production when T3 and T4 levels are high.
www.medhelp.org /glossary2/new/gls_4550.htm   (81 words)

  
 Healthopedia.com - TSH (Thyroid-Stimulating Hormone, Thyrotropin)
A TSH blood test measures the amount of thyroid-stimulating hormone, or TSH.
It stimulates the thyroid gland to release thyroid hormone, or thyroxine.
A TSH test is ordered to help diagnose disorders of the thyroid gland, hypothalamus, and pituitary gland.
www.healthopedia.com /tsh   (306 words)

  
 Thyroid-Stimulating Hormone (TSH)
Evaluation of therapy in hypothyroid patients, receiving various thyroid hormone preparations: low values are found in states of excessive thyroid replacement.
Among possible problems are the recovery phase of nonthyroidal illness, states of resistance to thyroid hormone, thyrotropin-producing tumors, thyroid status in acute psychiatric illness, early in thyrotoxicosis and in subacute thyroiditis.
TSH levels have been elevated or inappropriately detectable for high thyroid hormone levels in some patients with thyrotropin-secreting pituitary adenomas.
www.labcorp.com /datasets/labcorp/html/chapter/mono/ri010700.htm   (914 words)

  
 Thyroid-Stimulating Hormone and Thyroid-Stimulating Hormone Receptor Structure-Function Relationships -- Szkudlinski et ...
hormones, thyroid development was arrested in late gestation (93).
TSH is a member of the glycoprotein hormone family (155), structurally classified as part of the CKGF superfamily of structurally
in the course of thyroid autoimmune disorders (153).
physrev.physiology.org /cgi/content/full/82/2/473   (8299 words)

  
 The Thyrotropin (Thyroid-Stimulating Hormone) Receptor Is Expressed on Murine Dendritic Cells and on a Subset of ...
Hormone regulation of extrathymic gut T cell development: Involvement of thyroid stimulating hormone.
Hormone regulation of murine T cells: potent tissue-specific immunosuppressive effects of thyroxine targeted to gut T cells.
Thyroid hormones modulate thyrotropin-releasing hormone biosynthesis in tissues outside the hypothalamic-pituitary axis of male rate.
www.jimmunol.org /cgi/content/full/164/12/6158   (5341 words)

  
 Thyrostimulin, a heterodimer of two new human glycoprotein hormone subunits, activates the thyroid-stimulating hormone ...
of glycoprotein hormone receptors, the A2/B5 heterodimer was
TSH, LH, or FSH receptor cDNAs (16, 17) and incubated in DMEM/F12
Kudo, M., Osuga, Y., Kobilka, B.K., and Hsueh, A.J. Transmembrane regions V and VI of the human luteinizing hormone receptor are required for constitutive activation by a mutation in the third intracellular loop.
www.jci.org /cgi/content/full/109/11/1445   (4753 words)

  
 thyroid-stimulating hormone on Encyclopedia.com   (Site not responding. Last check: 2007-11-05)
Involvement of Thyroid Hormones in the Effect of Intracerebroventricular Leptin Infusion on Uncoupling Protein-3 Expression in Rat Muscle.
A longitudinal assessment of thyroid hormone concentrations in preterm infants younger than 30 weeks' gestation during the first 2 weeks of life and their relationship to outcome.
Bad for the bones: thwarted hormone leads to skeletal decay.
www.encyclopedia.com /html/X/X-thyroids.asp   (282 words)

  
 Measurement of Thyroid-stimulating Hormone Receptor Autoantibodies by ELISA -- Bolton et al. 45 (12): 2285 -- Clinical ...
to ~0.3 by TRAbs or by bovine TSH.
I-labeled TSH and PEG precipitation (5) in 56 sera
Binding characteristics of antibodies to the TSH receptor.
www.clinchem.org /cgi/content/full/45/12/2285   (1326 words)

  
 Immunometrics - Thyroid Stimulating Hormone (TSH) EIA Test Kit   (Site not responding. Last check: 2007-11-05)
The assay is an immunometric ('sandwich') EIA for the quantitative measurement of TSH in human serum or plasma.
TSH in the sample is bound by 2 monoclonal anti-TSH antibodies directed at different epitopes.
One antibody is attached to magnetic particles and the other is labelled with alkaline phosphatase.
www.immunometrics.co.uk /en_kit-TSH.htm   (225 words)

  
 Regulation of the Phosphatidylinositol 3-Kinase, Akt/Protein Kinase B, FRAP/Mammalian Target of Rapamycin, and ...
Regulation of the Phosphatidylinositol 3-Kinase, Akt/Protein Kinase B, FRAP/Mammalian Target of Rapamycin, and Ribosomal S6 Kinase 1 Signaling Pathways by Thyroid-stimulating Hormone (TSH) and Stimulating type TSH Receptor Antibodies in the Thyroid Gland -- Suh et al.
TSH induced a redistribution of PDK1 from the cytoplasm
in vitro and in the response to TSH in vivo.
www.jbc.org /cgi/content/abstract/278/24/21960   (605 words)

  
 Thyroid Stimulating Hormone (TSH)
Samples which are part of a TRH stimulation test should be clearly identified as such.
There is no high-dose hook effect for TSH concentrations up to 1000 µIU/ml.
For diagnostic purposes, the TSH findings should always be assessed in conjunction with the patient's medical history, clinical examination and other findings.
www.medicine.uiowa.edu /path_handbook/handbook/test1827.html   (284 words)

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