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 TSH (Thyroid Stimulating Hormone)
TSH produced and secreted by the anterior part of pituitary gland, has the role of regulating thyroid function with the formation and secretion of T3 and T4.
www.affiland.com /pituitary/htsh.htm   (45 words)

  
 Hormones of the Pituitary
stimulated by the arrival of thyrotropin releasing hormone (TRH) from the hypothalamus.
Synthesis and release of FSH is triggered by the arrival from the hypothalamus of gonadotropin-releasing hormone (GnRH).
The GH-secreting cells are stimulated to synthesize and release GH by the intermittent arrival of growth hormone releasing hormone (GHRH) from the hypothalamus.
users.rcn.com /jkimball.ma.ultranet/BiologyPages/P/Pituitary.html   (1333 words)

  
 Thyroid Deficiency: Online Reference For Health Concerns
Even when all other hormones are normal, a low level of trans-thyretrin could mean that you are not producing enough thyroid hormones and that it is not being delivered to the cells.
The patient's level of TSH is measured through a blood test, then the patient is given an injection of TRH (a harmless synthetic hormone, modeled after the TRH secreted by the hypothalamus gland in the brain); 25 minutes later blood is drawn and the TSH is measured again.
Hashimoto's thyroiditis is the most common form of hypothyroidism, presenting with an enlarged thyroid gland that becomes nonfunctional, with the active parts of the gland deteriorating after several years.
www.lef.org /protocols/prtcl-104.shtml   (2148 words)

  
 Thyroid Stimulating Hormone
TSH also increases the transcription of mRNA for thyroglobulin and thyroidal peroxidase (TPO), and increases the formation and activity of lysosomes which will hydrolyze the iodinated thyroglobulin to form thyroid hormones.
It is similar to the alpha subunit of follicle-stimulating hormone, luteinizing hormone and human chorionic gonadotropin.
TSH binds with membrane bound TSH receptors on the cells of the thyroid gland.
macromolonline.8m.com /endo/hormones/tsh.htm   (486 words)

  
 Thyroid-stimulating hormone - Freepedia
Thyroid-stimulating hormone (also known as TSH or thyrotropin) is a hormone produced by thyrotropes in the anterior pituitary gland which controls the endocrine function of the thyroid gland.
The thyroid-stimulating hormone test measures the amount of TSH in the blood, to see if the thyroid gland is overactive or underactive.
TSH stimulates the thyroid gland to secrete the hormones thyroxine (T4) and triiodothyronine (T3).
en.freepedia.org /TSH.html   (142 words)

  
 Hypothyroidism — Diagnosis
A normal range TSH indicates that the hypothalamus senses a normal amount of thyroid hormone and is stimulating the thyroid to continue making and releasing thyroid hormone at the same rate.
The TSH measurement is of fundamental importance since it reflects the sufficiency of the brain’s supply of thyroid hormone.
TSH measurement may help the physician to determine if the problem is primary (thyroid gland) or secondary (pituitary gland) hypothyroidism.
www.armourthyroid.com /hypothyroidism/diagnosis.html   (813 words)

  
 The Kelly G. Ripken Program - Free Thyroid Screening
Almost all patients with an underactive thyroid (hypothyroidism) or overactive thyroid (hyperthyroidism) can be diagnosed with a simple blood test, thyroid stimulating hormone, TSH.
TSH is released from the pituitary and stimulates the thyroid gland to liberate thyroid hormones.
The pituitary gland in the brain monitors the levels of thyroid hormone in the bloodstream.
thyroid-ripken.med.jhu.edu /testing   (104 words)

  
 The Thyroid Gland: A General Introduction thyroid disease goitre goiter iodine hormones
In Hashimoto's thyroiditis, the goitre is caused by an accumulation of white blood cells and fluid (inflammation) in the thyroid gland.
Abnormalities of the thyroid gland are common and affect one in twenty (1 in 20) of the Canadian population.
The thyroid gland is located in the front of the neck attached to the lower part of the voicebox (or larynx) and to the upper part of the windpipe (or trachea).
www.thyroid.ca /Guides/HG01.html   (987 words)

  
 TSH Test (Thyroid Stimulating Hormone)
TSH (thyroid stimulating hormone) is a chemical substance produced by the pituitary gland that stimulates the thyroid gland to synthesize and release its own hormones into the bloodstream.
Thyroid hormones control metabolism and organ function, directly affecting weight loss or gain, energy levels, skin condition, memory, heart rate, cholesterol levels, menstrual regularity, memory as well as many other functions.
When not enough thyroid hormone is produced, a condition called hypothyroidism will result, often referred to as an underactive thyroid.
www.healthworks2000.com /THSTest.htm   (1549 words)

  
 Thyroid-Stimulating Hormone (TSH)
TSH levels can help determine whether hypothyroidism is due to a damaged thyroid gland or some other cause (such as a problem with the pituitary gland or the hypothalamus).
TSH is produced when the hypothalamus releases a substance called thyrotropin-releasing hormone (TRH).
TSH levels that do not rise after the injection can indicate the presence of conditions such as a damaged pituitary gland (secondary hypothyroidism), Graves' disease, or any condition that causes an overactive thyroid gland (hyperthyroidism).
my.webmd.com /hw/health_guide_atoz/hw28656.asp   (1084 words)

  
 Rethinking the TSH Test: An Interview with David Derry, M.D., Ph.D.
The History of Thyroid Testing, Why the TSH Test Needs to Be Abandoned, and the Return to Symptoms-Based Thyroid Diagnosis and Treatment -- Articles / FAQs
David Derry: For many years the literature (before the TSH) supported the fact that if your symptoms responded to thyroid hormone you were low thyroid but especially if when you took the person off the thyroid and their symptoms returned.
However as the TSH was so sensitive to orally-given thyroid hormone it meant literally everyone was going to end up with a low dose by comparison with previous doses.
The main ingredient of thyroid hormone, which distinguishes it from other molecules of similar size (molecular size), was the element which made thyroid hormone namely iodine.
www.thyroid-info.com /articles/david-derry.htm   (4245 words)

  
 thyroid-stimulating hormone on Encyclopedia.com
A longitudinal assessment of thyroid hormone concentrations in preterm infants younger than 30 weeks' gestation during the first 2 weeks of life and their relationship to outcome.
Involvement of Thyroid Hormones in the Effect of Intracerebroventricular Leptin Infusion on Uncoupling Protein-3 Expression in Rat Muscle.
www.encyclopedia.com /html/X/X-thyroids.asp   (282 words)

  
 Thyrostimulin, a heterodimer of two new human glycoprotein hormone subunits, activates the thyroid-stimulating hormone receptor -- Nakabayashi et al. 109 (11): 1445 -- Journal of Clinical Investigation
of glycoprotein hormone receptors, the A2/B5 heterodimer was
Kudo, M., Osuga, Y., Kobilka, B.K., and Hsueh, A.J. Transmembrane regions V and VI of the human luteinizing hormone receptor are required for constitutive activation by a mutation in the third intracellular loop.
TSH, LH, or FSH receptor cDNAs (16, 17) and incubated in DMEM/F12
www.jci.org /cgi/content/full/109/11/1445   (4753 words)

  
 Thyroid-Stimulating Hormone
Thyroid-stimulating hormone, also known as thyrotropin, is secreted from cells in the anterior pituitary called thyrotrophs, finds its receptors on epithelial cells in the thyroid gland, and stimulates that gland to synthesize and release thyroid hormones.
The alpha subunit of TSH is also present in two other pituitary glycoprotein hormones, follicle-stimulating hormone and luteinizing hormone, and, in primates, in the placental hormone chorionic gonadotropin.
Secretion of thyroid-releasing hormone, and hence, TSH, is inhibited by high blood levels of thyroid hormones in a classical negative feedback loop.
arbl.cvmbs.colostate.edu /hbooks/pathphys/endocrine/hypopit/tsh.html   (239 words)

  
 THYROID STIMULATING HORMONE
Thyroid stimulating hormone (TSH) stimulates the thyroid to produce more thyroid hormones (T4 and T3).
A hormone which is secreted by the anterior pituitary gland.
T4 and T3 blood levels feedback on the pituitary gland and decrease TSH production when T3 and T4 levels are high.
www.medhelp.org /glossary2/new/gls_4550.htm   (81 words)

  
 Healthopedia.com - TSH (Thyroid-Stimulating Hormone, Thyrotropin)
A TSH blood test measures the amount of thyroid-stimulating hormone, or TSH.
It stimulates the thyroid gland to release thyroid hormone, or thyroxine.
A TSH test is ordered to help diagnose disorders of the thyroid gland, hypothalamus, and pituitary gland.
www.healthopedia.com /tsh   (306 words)

  
 Thyroid-stimulating Hormone Levels in Children from Chernobyl
This preliminary study assesses thyroid function in immigrants who were children (0 to 16 years of age) at the time of the Chernobyl accident and reports on preliminary results of assessments of thyroid-stimulating hormone (TSH) serum levels in these young people.
Hence, elevated TSH in a population group could be a marker for prior exposure of the thyroid to environmental radioiodine.
A working hypothesis is proposed by which the shift in TSH levels in girls from high radiocontamination areas was associated with subclinical radiation damage from environmental radioiodine at the time of the accident.
ehp.niehs.nih.gov /members/1997/Suppl-6/quastel-full.html   (1428 words)

  
 THYROID STIMULATING HORMONE
Thyroid (thi-roid) stimulating hormone (TSH) is found in the blood.
TSH may be the best single test to see if your thyroid gland is working OK. Sometimes it may be necessary to do other thyroid tests at the same time as the TSH.
TSH can be measured in your blood by a special laboratory test to see how your thyroid gland is working.
www.medformation.com /ac/mm_qdis.nsf/qd/nd7014g.htm   (510 words)

  
 TSH: The Test
A high TSH value can also occur when patients with a known thyroid disorder (or those who have had their thyroid gland removed) are receiving too little thyroid hormone medication.
Many medications — including aspirin and thyroid-hormone replacement therapy — may affect thyroid gland function test results, so tell your doctor about any drugs you are taking.
A high TSH result often means an underactive thyroid gland that is not responding adequately to the stimulation of TSH due to some type of acute or chronic thyroid dysfunction.
www.labtestsonline.org /understanding/analytes/tsh/test.html   (629 words)

  
 Thyroid-Stimulating Hormone (TSH)
Among possible problems are the recovery phase of nonthyroidal illness, states of resistance to thyroid hormone, thyrotropin-producing tumors, thyroid status in acute psychiatric illness, early in thyrotoxicosis and in subacute thyroiditis.
TSH levels have been elevated or inappropriately detectable for high thyroid hormone levels in some patients with thyrotropin-secreting pituitary adenomas.
Evaluation of therapy in hypothyroid patients, receiving various thyroid hormone preparations: low values are found in states of excessive thyroid replacement.
www.labcorp.com /datasets/labcorp/html/chapter/mono/ri010700.htm   (914 words)

  
 How Your Thyroid Works
Your thyroid gland is a small gland, normally weighing less than one ounce, located in the front of the neck.
During development (inside the womb) the thyroid gland originates in the back of the tongue, but it normally migrates to the front of the neck before birth.
Thyroid cells are the only cells in the body which can absorb iodine.
www.endocrineweb.com /thyfunction.html   (473 words)

  
 Adult Health Advisor 2005.2: Thyroid-Stimulating Hormone (TSH) Test
When your thyroid gland is underactive and not producing enough thyroid hormone, your body produces more TSH to stimulate the gland and increase its activity.
You had an overactive thyroid gland that was removed or destroyed and you are not taking enough replacement thyroid hormone.
When your thyroid gland is overactive and producing too much thyroid hormone, your body decreases the amount of TSH to slow production of thyroid hormone.
www.med.umich.edu /1libr/aha/aha_thystiho_crs.htm   (608 words)

  
 Immunometrics - Thyroid Stimulating Hormone (TSH) EIA Test Kit
The assay is an immunometric ('sandwich') EIA for the quantitative measurement of TSH in human serum or plasma.
TSH in the sample is bound by 2 monoclonal anti-TSH antibodies directed at different epitopes.
One antibody is attached to magnetic particles and the other is labelled with alkaline phosphatase.
www.immunometrics.co.uk /en_kit-TSH.htm   (225 words)

  
 Measurement of Thyroid-stimulating Hormone Receptor Autoantibodies by ELISA -- Bolton et al. 45 (12): 2285 -- Clinical Chemistry
Novel insights into the molecular mechanisms of human thyrotropin action: structural, physiological, and therapeutic implications for the glycoprotein hormone family.
I-labeled TSH and PEG precipitation (5) in 56 sera
to ~0.3 by TRAbs or by bovine TSH.
www.clinchem.org /cgi/content/full/45/12/2285   (1326 words)

  
 MedlinePlus Medical Encyclopedia: TSH
TSH subsequently stimulates the thyroid to produce thyroid hormone, T3 and T4.
TSH is a test that measures the amount of the hormone TSH in the blood.
Some people with a TSH value over 2.5 mIU/L who have no signs (that is, no other abnormal thyroid function tests) or symptoms suggestive of an under-active thyroid may develop hypothyroidism sometime in the future.
www.nlm.nih.gov /medlineplus/ency/article/003684.htm   (713 words)

  
 Thyroid-Stimulating Hormone and Thyroid-Stimulating Hormone Receptor Structure-Function Relationships -- Szkudlinski et al. 82 (2): 473 -- Physiological Reviews
hormones, thyroid development was arrested in late gestation (93).
in the course of thyroid autoimmune disorders (153).
TSH is a member of the glycoprotein hormone family (155), structurally classified as part of the CKGF superfamily of structurally
physrev.physiology.org /cgi/content/full/82/2/473   (8299 words)

  
 Thyroid-stimulating hormone (TSH)
Thyroid-stimulating hormone (TSH) is produced by and stored in the pituitary gland, which is located beneath the brain.
The release of TSH into the bloodstream stimulates the thyroid gland to release its hormones, called thyroxine (T4) and triiodothyronine (T3).
When the pituitary gland detects that thyroid hormone levels are too low, it secretes more TSH.
my.webmd.com /hw/health_guide_atoz/stt11521.asp   (99 words)

  
 Thyroid stimulating hormone definition - Thyroid: health and medical information about Thyroid Disease, Hypothyroidism, Hyperthyroidism and Thyroid Disease
Thyroid stimulating hormone: A hormone produced by the pituitary gland at the base of the brain in response to signals from the hypothalamus gland in the brain.
Thyroid stimulating hormone (TSH) promotes the growth of the thyroid gland in the neck and stimulates it to produce more thyroid hormones.
Thyroid stimulating hormone definition - Thyroid: health and medical information about Thyroid Disease, Hypothyroidism, Hyperthyroidism and Thyroid Disease
www.medterms.com /script/main/art.asp?articlekey=5781   (292 words)

  
 Thyroid Stimulating Hormone (TSH)
For diagnostic purposes, the TSH findings should always be assessed in conjunction with the patient's medical history, clinical examination and other findings.
Samples which are part of a TRH stimulation test should be clearly identified as such.
There is no high-dose hook effect for TSH concentrations up to 1000 µIU/ml.
www.medicine.uiowa.edu /path_handbook/rhandbook/test1827.html   (298 words)

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