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| | Neurology Journal Club Aricle #1 (Site not responding. Last check: 2007-10-10) |
 | | The tibial nerve specimen obtained from this dog at the time of the second biopsy had a similar percentage of abnormal fibers as the sciatic nerve, but the frequency of axonal degeneration was higher in the distal specimen (Table 2). |
 | | Nerve sample lost for single fiber processing; however, axonal necrosis, demyelination, and nerve fiber loss were observed in semithin tissue sections. |
 | | Ultrastructurally, peripheral nerves from affected dogs were characterized by loss of myelinated fibers, marked increase in endoneurial collagen, axonal degeneration (Fig 4), multifocal myelinoaxonal necrosis (Fig 5), numerous Bungner bands (conglomerations of Schwann cells previously associated with myelinated axons)29 (Fig 6), multifocal macrophage infiltration, occasional regenerating clusters, and presence of dark endoneurial fibroblasts. |
| neuro.vetmed.ufl.edu /neuro/journal_club/articles/malamute_art.htm (2964 words) |
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