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Timolol (PIM 531) Timolol is contraindicated in patients with asthma, 2nd and 3rd degree AV block, and cardiogenic shock. Timolol is extensively metabolized in the liver by hydrolytic cleavage of the morpholino ring with subsequent oxidation. Timolol is eliminated in breast milk but the total amount of timolol ingested by an infant who is breast feeding is unlikely to cause clinical effects. www.inchem.org /documents/pims/pharm/timolol.htm   (1721 words)

Howstuffworks "Timolol Maleate: A Profile of a Beta Blocker" Timolol is used to treat high blood pressure and to prevent additional heart attacks in heart attack patients. Timolol tablets can be taken with a glass of water, with meals, immediately following meals, or on an empty stomach, depending on your doctor's instructions. It is important to remember that timolol maleate does not cure high blood pressure, but it will help to control the condition as long as you continue to take it. health.howstuffworks.com /define-timolol-maleate-systemic.htm   (1189 words)

Timolol patient advice including side effects Timolol is a topical medication (applied directly in the eye) that effectively reduces internal pressure in the eye. Timolol is used in the treatment of glaucoma to lower elevated eye pressure that could damage vision and, with other glaucoma medications, to further reduce pressure in the eye. Timolol should not be used with other topical beta blockers and should be used with caution if you are taking oral beta blockers such as Inderal and Tenormin. www.drugs.com /pdr/timolol.html   (1234 words)

Timolol   (Site not responding. Last check: 2007-08-09) Timolol is not approved for use in animals by the Food and Drug Administration (FDA), but it is prescribed legally by veterinarians as an [[rolextra-labelThe medical use of a drug for a purpose, or in a species, not approved “on the label” by the FDA. Timolol is used in cases of glaucoma in dogs and cats. Because timolol is a non-selective beta-blocker it must be used with caution, or avoided in animals with congestive heart failure and certain respiratory conditions, such as allergic bronchitis, asthma and obstructive pulmonary diseases. www.petplace.com /drug-library/timolol/page1.aspx   (854 words)

Timolol GFS Online, Description, Chemistry, Ingredients - Timolol Maleate - RxList Monographs   (Site not responding. Last check: 2007-08-09) Timolol GFS (timolol maleate ophthalmic gel forming solution) is a non-selective beta-adrenergic receptor blocking agent.Its chemical name is (-)-1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]-2-propanol maleate (1:1) (salt).Timolol maleate possesses an asymmetric carbon atom in its structure and is provided as the levo-isomer. Timolol maleate has a molecular weight of 432.50.It is a white, odorless, crystalline powder which is soluble in water, methanol, and alcohol. Timolol GFS is supplied as a sterile, isotonic, buffered, aqueous solution of timolol maleate in two dosage strengths. www.rxlist.com /cgi/generic3/timololgfs.htm   (224 words)

timolol   (Site not responding. Last check: 2007-08-09) Timolol is effective in treating mild to moderate hypertension. Timolol has been favoured for local use in the eye because it lacks local anesthetic properties and is a pure antagonist. Timolol is relatively free of CNS side effects because of its lower lipid solubility and thus poor access to the brain. lysine.pharm.utah.edu /netpharm/netpharm_00/druglist/timolol.htm   (268 words)

Howstuffworks "Timolol: A Profile of an Antiglaucoma Ophthalmic Solution" Timolol (ophthalmic) is used to reduce pressure in the eye caused by glaucoma or other eye conditions. Keep your eyes closed, and place one finger at the corner of the treated eye next to your nose for a minute or two, applying a slight pressure (this is done to prevent loss of medication through the duct that drains fluid from the surface of the eye into the nose and throat). Timolol (ophthalmic) may interact with certain other medications: It may increase the side effects of reserpine, oral beta blockers, calcium channel blockers, digoxin, quinidine, and phenothiazine tranquilizers. health.howstuffworks.com /define-timolol-ophthalmic.htm   (908 words)

Timolol   (Site not responding. Last check: 2007-08-09) Timolol is available alone and in a combination product used to lower blood pressure. Timolol is also available in eye drop and eye gel preparations used to lower high internal eye pressure due to In a group of 16 glaucoma patients treated with a timolol eye preparation, six weeks of oral coenzyme Q10 (90 mg per day) was reported to reduce timolol-induced cardiovascular side effects without affecting intraocular pressure treatment. www.kroger.com /hn/Drug/Timolol.htm   (482 words)

dorzolamide and timolol ophthalmic Consumer Drug Information Timolol ophthalmic is a beta-blocker that also reduces pressure inside the eye. The combination of dorzolamide and timolol ophthalmic is used to treat certain types of glaucoma and other causes of high pressure inside the eye. Use dorzolamide and timolol ophthalmic exactly as it was prescribed for you. www.drugs.com /MTM/dorzolamide_and_timolol_ophthalmic.html   (1552 words)

MedlinePlus Drug Information: Timolol Ophthalmic Timolol is used to treat glaucoma, a condition in which increased pressure in the eye can lead to gradual loss of vision. Timolol eyedrops usually are applied once or twice a day, at evenly spaced intervals, until pressure in your eyeball is controlled (about 4 weeks). Timolol gel usually is applied once a day. www.nlm.nih.gov /medlineplus/druginfo/medmaster/a682043.html   (884 words)

Numark | Timolol Timolol is a beta-blocker drug used to lower blood pressure in people with hypertension, treat people after Timolol is also available in eye drop and eye gel preparations used to lower high internal eye pressure due to glaucoma and other conditions. In a group of 16 glaucoma patients treated with a timolol eye preparation, six weeks of oral co-Enzyme Q10 (90 mg per day) was reported to reduce timolol-induced cardiovascular side effects without affecting intra-ocular pressure treatment. www.numarkpharmacists.com /hn/Drug/Timolol.htm   (556 words)

Transdermal formulation of timolol Timolol maleate is a beta adrenoceptor-blocking agent used in treatment of cardiovascular diseases like myocardial infarction, angina pectoris, hypertension, respiratory complications and migraine. The main limitation of therapeutic effectiveness of timolol maleate is its higher frequency of drug dosing and short biological half-life, high first pass metabolism and poor bioavailability by oral route. It is rapidly absorbed from gastrointestinal tract with peak plasma concentration of 5-10 ng/ ml after 1 hr2, it is metabolized up to 80% in liver with a mean half-life of 2.0-2.5 hr.3, thus necessitating frequent administration of larger doses to maintain therapeutic drug level. www.priory.com /pharmol/timolol.htm   (1564 words)

timolol - [Medication] Timolol is only part of a complete program of treatment for hypertension that may also include diet, exercise, and weight control. Timolol is in a group of drugs called beta-blockers. Timolol is used to treat hypertension (high blood pressure). www.peacehealth.org /kbase/multum/d00139a1.htm   (1291 words)

MedlinePlus Drug Information: Timolol Oral If timolol is stopped suddenly, it may cause chest pain or heart attack in some people. Timolol is used to treat high blood pressure. Timolol also is used to prevent migraine headaches. www.nlm.nih.gov /medlineplus/druginfo/medmaster/a684029.html   (677 words)

Timoptic Online, Description, Chemistry, Ingredients - Timolol Maleate - RxList Monographs   (Site not responding. Last check: 2007-08-09) Timolol maleate is a non-selective beta-adrenergic receptor blocking agent. Timolol maleate possesses an asymmetric carbon atom in its structure and is provided as the levo-isomer. Timoptic ophthalmic solution is supplied as a sterile, isotonic, buffered, aqueous solution of timolol maleate in two dosage strengths: each ml of Timoptic 0.25% contains 2.5 mg of timolol (3.4 mg of timolol maleate). www.rxlist.com /cgi/generic/timolol.htm   (430 words)

hydrochlorothiazide and timolol Timolol is in a class of drugs called beta-blockers. Timolol is used to lower blood pressure, lower heart rate, reduce angina (chest pain), and reduce the risk of recurrent heart attacks. Hydrochlorothiazide and timolol is in the FDA pregnancy category C. This means that it is not known whether hydrochlorothiazide and timolol will harm an unborn baby. hw.healthdialog.com /kbase/multum/d03260a1.htm   (1396 words)

timolol ophthalmic solution - Eye Disorders including cataracts, Lasik eye surgery, blindness, glaucoma and eye allergy   (Site not responding. Last check: 2007-08-09) In addition to its effect on the heart, timolol causes a reduction of the pressure within the eye (intraocular pressure). Timolol was approved by the FDA for ocular use in 1978. It is unknown if the small amount of timolol that penetrates into the blood after administration into the eye affects the fetus. www.medicinenet.com /timolol_ophthalmic_solution/article.htm   (601 words)

Timoptic - Drugs & Vitamins - Drug Library - DrugDigest TIMOLOL (Istalol™, Timoptic®, Timoptic-XE™, Betimol®) belongs to a group of medicines called beta-blockers. Timolol lowers increased pressures within the eye and is effective in treating certain types of glaucoma. Timolol eye solution is only for use in the eye. www.drugdigest.org /DD/DVH/Uses/0,3915,660|Timoptic,00.html   (720 words)

timolol Timolol is used to reduce hypertension (high blood pressure), to treat angina (chest pain), and to reduce the risk that a heart attack will recur. Timolol is in the FDA pregnancy category C. This means that it is not known whether timolol will harm an unborn baby. Timolol passes into breast milk and may affect a nursing infant. hw.healthdialog.com /kbase/multum/d00139a1.htm   (1203 words)

Glaucoma Medications Like propranolol, timolol possesses a relatively high degree of lipid solubility and is subject to first-pass metabolism by the liver. Timolol was approved by the FDA for optical use in 1978, and for oral use in 1981. Since timolol is a nonspecific beta-blocker, it should not be used with albuterol, metoproterenol, or other beta2-agonists; or epinephrine, norepinephrine, or other cardiovascular stimulants. www.blinddogs.com /glaucoma-meds.htm   (1733 words)

Xalatan Monotherapy Equivalent To Timolol/Dorzolamide Combination For IOP   (Site not responding. Last check: 2007-08-09) IOP reduction was achieved following a switch from timolol to latanoprost in this group and the addition of dorzolamide to timolol in other patients not adequately controlled on timolol alone. After a two to four week run-in period on timolol, 5mg ml/twice daily, the patients were randomised to treatment with either latanoprost, 50 mcg/ml once daily, or the combination of timolol, 5 mg/ml twice daily and dorzolamide 20 mg/ml twice daily. Switching from timolol to latanoprost reduced mean diurnal IOP by 4.5 plus/minus 0.2 mmHg and adding dorzolamide to timolol reduced mean diurnal IOP by 4.4 plus/minus 0.2 mmHg. www.pslgroup.com /dg/C0E82.htm   (697 words)

A randomised, double masked, multicentre clinical trial comparing bimatoprost and timolol for the treatment of glaucoma ... Mean IOP was significantly lower with bimatoprost once daily than with timolol at 8 am, 10 am, and 4 pm. Mean IOP in the bimatoprost twice daily group was significantly lower than in the timolol group at 8 am and 4 pm. Comparison the ocular hypotensive lipid AGN 192024 with timolol: dosing, efficacy, and safety evaluation of a novel compound for glaucoma management. bjo.bmj.com /cgi/content/full/87/1/57   (3054 words)

Conjunctival Proinflammatory and Proapoptotic Effects of Latanoprost and Preserved and Unpreserved Timolol: An Ex Vivo ... Comparison of latanoprost and timolol in patients with ocular hypertension and glaucoma: a six-month, masked, multicenter trial in the United States. Enhanced disruption of the blood-aqueous barrier and the incidence of angiographic cystoid macular edema by topical timolol and its preservative in early postoperative pseudophakia. Short-term effect of latanoprost and timolol eye drops on tear fluid and the ocular surface in patients with primary open-angle glaucoma and ocular hypertension. www.iovs.org /cgi/content/full/45/5/1360   (5123 words)

TIMOLOL   (Site not responding. Last check: 2007-08-09) Timolol is suitable for treatment of open-angle glaucoma (glaucoma simplex), but can also be used for secondary glaucoma (e.g. It can be traced in small quantities in the breast milk of nursing mothers, however Timolol can be given during the nursing period. Timolol is generally well tolerated, although its membrane stabilising activity can give rise to corneal anaesthesia www.chem.ox.ac.uk /course/ityearone/week2/TIMOLOL.htm   (254 words)

A 12 week study comparing the fixed combination of latanoprost and timolol with the concomitant use of the individual ... timolol with that of the concomitant use of the individual components. A short-term study of the additive effect of timolol and brimonidine on intraocular pressure. Intraocular pressure-lowering effects of latanoprost monotherapy versus latanoprost or pilocarpine in combination with timolol: a randomized, observer-masked multicenter study in patients with open-angle glaucoma. bjo.bmjjournals.com /cgi/content/full/88/2/199   (3386 words)

Timolol Eye Preparations - Patient UK Timolol works by reducing the production of fluid in the eye, reducing the pressure. Timolol can also be useful in treating other conditions which cause increased pressure in the eye. Timolol is available in eye drop and eye gel (released as drops) form. www.patient.co.uk /showdoc/30002122   (788 words)

Medical Dictionary: Timolol - WrongDiagnosis.com Timolol has been proposed as an antihypertensive, antiarrhythmic, antiangina, and antiglaucoma agent. Because many drug names share similar spellings or sound almost identical when spoken, it is possible to mistake the name of a particular medication. The following list attempts to classify Timolol into categories where each line is subset of the next. www.wrongdiagnosis.com /medical/timolol.htm   (286 words)

AAO: Combination Of Latanoprost And Timolol Superior To Each Drug Individually   (Site not responding. Last check: 2007-08-09) In this study, 418 patients were randomized to two groups to take either latanoprost 0.005%, or timolol 0.5% together (Xalacom) or timolol twice daily, or latanopost once daily. A sub-group analysis showed that the reduction in IOP was even more favorable among subjects who had visual defects as a result of their elevated IOP. Subjects with visual defects had a reduction in 8:00AM IOP of 3.75 mmHg (mean) as compared with timolol, while for those who did not have visual defects, the mean reduction was only 2 mmHg at week two of the study. www.pslgroup.com /dg/20DDD6.htm   (525 words)

A comparison of the fixed combination of latanoprost and timolol with the unfixed combination of brimonidine and ... A comparison of the fixed combination of latanoprost and timolol with the unfixed combination of brimonidine and timolol in patients with elevated intraocular pressure. The efficacy of dorzolamide, a topical carbonic anhydrase inhibitor, in combination with timolol in the treatment of patients with open-angle glaucoma and ocular hypertension. A comparison of latanoprost and timolol in primary open-angle glaucoma and ocular hypertension. bjo.bmjjournals.com /cgi/content/full/88/7/877   (3476 words)

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