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| | eMedicine - Toxicity, Vitamin : Article by Mark Rosenbloom, MD, MBA, FACEP |
 | | This particular toxicity is typically associated with formula-fed infants or those receiving synthetic vitamin K-3 (menadione) injections. |
 | | Acute toxicity effects are prostaglandin-mediated and include flushing, pruritus, wheezing, vasodilation, headache, increased intracranial blood flow, headache, diarrhea, and vomiting. |
 | | Chronic toxicity effects include jaundice, abnormal liver function tests, signs and symptoms of liver toxicity (most common with sustained-release preparations), and acanthosis nigricans (rare). |
| www.emedicine.com /emerg/topic638.htm (2722 words) |
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