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Topic: Tramadol

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	Tramadol Information from Drugs.com
		While you are taking tramadol, do not drink alcohol or use drugs that make you sleepy (such as cold medicine, other pain medications, muscle relaxants, and medicine for seizures, depression or anxiety).
		Tramadol may also cause serious or fatal side effects in a newborn if the mother uses the medication during pregnancy or labor.
		Tramadol can be taken with or without food, but take it the same way each time.
	www.drugs.com /tramadol.html (1827 words)

	Tramadol - Wikipedia, the free encyclopedia
		Tramadol is available in both injectable (intravenous and/or intramuscular) and oral preparations including the extended-release tablet Ultram ER (100,200,300).
		The contribution of non-opioid activity is demonstrated by the analgesic effects of tramadol not being fully antagonised by the μ-opioid receptor antagonist naloxone.
		Tramadol is marketed as a racemic mixture with a weak affinity for the μ-opioid receptor (approximately 1/6000th that of morphine).
	en.wikipedia.org /wiki/Tramadol (908 words)

	Tramadol Pain Relief
		The contribution of non-opioid activity is demonstrated by the analgesic effects of tramadol not being fully antagonised by the μ-opioid receptor antagonist naloxone.
		Tramadol is marketed as a racemic mixture with a weak affinity for the μ-opioid receptor (approximately 1/6000th that of morphine).
		Tramadol is an atypical opioid which is a centrally acting analgesic, used for treating moderate to severe pain.
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		Hepatic: Metabolism of tramadol and M1 is reduced in patients with advanced cirrhosis of the liver resulting in a larger area under the serum-concentration-versus-time to curve tramadol and longer tramadol and M1 elimination half-lives (13 hrs.
		Tramadol has been shown to be embryotoxic and fetotoxic in mice, rats and rabbits and maternally toxic doses 3 to 15 times the maximum human dose or higher (120 mg/kg in mice, 25 mg/kg or higher in rats and 75 mg/kg or higher in rabbits), but was not teratogenic at these dose levels.
		Tramadol, a synthetic opioid of the aminocyclohexanol group, is a centrally acting analgesic with weak opioid agonist properties, and effects on noradrenergic and serotonergic neurotransmission.
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	tramadol (Ultram) Drug Information by MedicineNet.com
		Like morphine, tramadol binds to receptors in the brain (opioid receptors) that are important for transmitting the sensation of pain from throughout the body to.
		Tramadol is not a nonsteroidal antiinflammatory drug (NSAID) and does not have the increased risk of stomach ulceration and internal bleeding that can occur with NSAIDs.
		Tramadol may increase central nervous system and respiratory depression when combined with alcohol, anesthetics, narcotics, tranquilizers or sedative hypnotics.
	www.medicinenet.com /tramadol/article.htm (627 words)

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		Tramadol hydrochloride is a white, bitter, crystalline and odorless powder.
		The number of doses of tramadol you take each day, the time allowed between doses, and the length of time you take the tramadol drug depend on the medical problem for which you are taking tramadol.
		The effects of tramadol are similar to those of narcotic analgesics, but tramadol is not considered to be narcotic.
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	Tramadol
		Tramadol may possibly increase the risk of seizures in those with a history of epilepsy or those on medication, which lowers the seizure threshold, but it appears that tramadol does not induce idiopathic seizures except at very high doses.
		Tramadol is contraindicated in users of MAO inhibitors as a safety precaution and, because of the risk of serotonin syndrome, should be used with caution in combination with SSRIs.
		Tramadol (Tramal™) is a synthetic, centrally-acting analgesic used parenterally and orally for the treatment of moderate to severe pain.
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		In vitro studies indicate that Tramadol (Ultram) is unlikely to inhibit the CYP3A4-mediated metabolism of other drugs when Tramadol (Ultram) is administered concomitantly at therapeutic doses.Tramadol (Ultram) does not appear to induce its own metabolism in humans, since observed maximal plasma concentrations after multiple oral doses are higher than expected based on single-dose data.
		Tramadol (Ultram) is a mild inducer of selected drug metabolism pathways measured in animals.
		Because carbamazepine increases tramadol metabolism and because of the seizure risk associated with tramadol, concomitant administration of ULTRAM and carbamazepine is not recommended.
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	MedlinePlus Drug Information: Tramadol
		Tramadol is used to relieve moderate to moderately severe pain.
		Tramadol extended-release tablets are only used by people who are expected to need medication to relieve pain around-the-clock for a long time.
		Your doctor may start you on a low dose of tramadol and gradually increase the amount of medication you take, not more often than every 3 days if you are taking the regular tablets or every 5 days if you are taking the extended-release tablets.
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	Tramadol - HealthBoards
		The risk of seizures may be increased in patients who take more than the prescribed dose, have a history of seizures or epilepsy, have head trauma, have a metabolic disorder, have a central nervous system infection, are experiencing alcohol or drug withdrawal, or are taking certain medications.
		Tramadol affects chemicals and receptors in the body that are associated with pain.
		The maximum daily dose of tramadol for people over 75 years of age is 300 mg.
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	Tramadol - Drugs Store - drugsstore.org
		Tramadol (INN) (IPA:) is an atypical opioid which is a centrally acting analgesic, used for treating moderate to severe pain.
		Tramadol is available in both injectable (intravenous and/or intramuscular) and oral preparations.
		Similarly, tramadol is not currently scheduled by the U.S. DEA, unlike other opioid analgesics.
	www.drugsstore.org /tramadol.html (778 words)

	Ultram (Tramadol Hcl) drug description - prescription drugs and medications at RxList
		ULTRAM® (tramadol hydrochloride tablets) is a centrally acting analgesic.
		Tramadol hydrochloride is a white, bitter, crystalline and odorless powder.
		ULTRAM tablets contain 50 mg of tramadol hydrochloride and are white in color.
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	Tramadol - Patient UK
		Your doctor may be able to prescribe medicines to take with tramadol to help with these side effects.
		Make sure your reactions are normal before driving, operating machinery or doing any other jobs which could be dangerous if you were not fully alert.
		Tramadol is used to relieve severe pain; it works on the nerves and brain to reduce the pain you feel.
	www.patient.co.uk /showdoc/30002834 (840 words)

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