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Topic: Transpeptidase

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	Identity of maleate-stimulated glutaminase with gamma-glutamyl transpeptidase in rat kidney.
		Gamma-Glutamyl transpeptidase was purified from rat kidney by a procedure involving Lubrol extraction, acetone precipitation, ammonium sulfate fractionation, treatment with bromelain, and column chromatography on DEAE-cellulose and Sephadex G-100.
		The purified transpeptidase (enzyme III) is similar to the phosphate-independent maleate-stimulated glutaminase preparation obtained from rat kidney by Katunuma and colleagues with respect to amino acid and carbohydrate content, apparent molecular weight, and relative transpeptidase and maleate-stimulated "glutaminase" activities.
		The studies on the ontogeny of gamma-glutamyl transpeptidase and other data are considered in relation to the proposal that this enzyme is involved in amino acid and peptide transport.
	www.arclab.org /medlineupdates/abstract_237905.html (431 words)

	glutamyl transpeptidase, Primary Sclerosing Cholangitis Literature
		Chida K 1990 Histochemical and immunohistochemical study on the expression of alkaline phosphatase, gamma-glutamyl transpeptidase and alpha-fetoprotein during the process of rat hepatocyte proliferation.
		Kampa IS, Jarzabek J, Clain J 1976 The use of gamma-glutamyl transpeptidase in differentiating liver from bone isoenzymes of alkaline phosphatase.
		Selinger MJ, Matloff DS, Kaplan MM 1982 gamma-Glutamyl transpeptidase activity in liver disease: serum elevation is independent of hepatic GGTP activity.
	www.psc-literature.org /ggt.htm (11126 words)

	Marie H. Hanigan's Publications
		Hanigan, M.H. (1996) Gamma-Glutamyl Transpeptidase, A Glutathionase: Its Expression in Carcinogenesis.
		Townsend, D.M. and Hanigan, M.H. (2000) In vivo Metabolism of Cisplatin to a Nephrotoxin by Gamma-Glutamyl Transpeptidase and Beta-Lyase.
		Townsend, D.M., Marto, J.A., Macdonald, T.L. and Hanigan, M.H. (2001) Characterization of a Glutathione Conjugate of Cisplatin that is Metabolized by Gamma-Glutamyl Transpeptidase to a Nephrotoxin.
	w3.ouhsc.edu /cell_biology/faculty/haniganpubs.html (1774 words)

	High-Throughput Screen for Inhibitors of Transglycosylase and/or Transpeptidase Activities of Escherichia coli ...
		of the transglycosylase and transpeptidase (moenomycin and penicillin,
		Tests were performed with inhibitors of the transglycosylase (moenomycin); an inhibitor of the MraY, MurG, transglycosylase, and transpeptidase (vancomycin); and ß-lactams, inhibitors of the transpeptidase (penicillin and ceftriaxone).
		Abbreviations: PG, peptidoglycan; TG, transglycosylase; TP, transpeptidase; Lpp'ase, lipid pyrophosphorylase.
	aac.asm.org /cgi/content/full/48/1/30 (6385 words)

	Inhibition of gamma -Glutamyl Transpeptidase or Cysteine S-Conjugate beta -Lyase Activity Blocks the Nephrotoxicity of ...
		deCeaurriz J and Ban M (1990) Role of gamma-glutamyl transpeptidase and beta-lyase in the nephrotoxicity of hexachloro-1,3-butadiene and methyl mercury in mice.
		Hanigan MH, Frierson HF, Jr and Taylor PT, Jr (1998) Expression of gamma-glutamyl transpeptidase in stage III and IV ovarian surface epithelial carcinomas does not alter response to primary cisplatin-based chemotherapy.
		Hanigan MH, Gallagher BC, Townsend DM and Gabarra V (1999) Gamma-glutamyl transpeptidase accelerates tumor growth and increases the resistance of tumors to cisplatin in vivo.
	jpet.aspetjournals.org /cgi/content/full/300/1/142 (4374 words)

	Gamma glutamyl transpeptidase and mean corpuscular volume: their usefulness in the assessment of in-patient alcoholics ...
		Gamma glutamyl transpeptidase and mean corpuscular volume: their usefulness in the assessment of in-patient alcoholics -- Latcham 149 (3): 353 -- The British Journal of Psychiatry
		Gamma glutamyl transpeptidase and mean corpuscular volume: their usefulness in the assessment of in-patient alcoholics
		Gamma glutamyl transpeptidase and mean corpuscular volume are shown to be
	bjp.rcpsych.org /cgi/content/abstract/149/3/353 (100 words)

	Game Levels
		The most common laboratory measures classified as liver function tests (LFTs) include the enzyme tests (principally the serum aminotransferases, alkaline phosphatase, and gamma glutamyl transpeptidase), the serum bilirubin, and tests of synthetic function (principally the serum albumin concentration and prothrombin time).
		The gamma glutamyl transpeptidase (GGT) test helps to detect liver and bile duct injury.
		While some doctors use it in all people they suspect of having liver disease, others use it only to help explain the cause of other changes or if they suspect alcohol abuse.
	www.medhelp.org /forums/Gastro/messages/35459a.html (466 words)

	Alcohol, high blood pressure, and serum gamma-glutamyl transpeptidase level -- Yamada et al. 18 (6): 819 -- Hypertension
		Alcohol, high blood pressure, and serum gamma-glutamyl transpeptidase level -- Yamada et al.
		The influence of the level of serum gamma-glutamyl transpeptidase, a
		transpeptidase levels above 50 units/l than in those with normal levels.
	hyper.ahajournals.org /cgi/content/abstract/18/6/819 (318 words)

	An Evaluation of Gamma-Glutamyl Transpeptidase (GGT) and p30 Determination for the Identification of Semen on ... (Site not responding. Last check: 2007-11-03)
		An Evaluation of Gamma-Glutamyl Transpeptidase (GGT) and p30 Determination for the Identification of Semen on Postcoital Vaginal Swabs.
		Abstract: The following study entails the investigation of gamma-glutamyl transpeptidase (GGT) and p30 for the identification of seminal stains in sexual assault cases.
		A commercial kit was used to test to GGT activity, while p30 was demonstrated with a crossed electrophoresis technique.
	www.astm.org /jforensicsci/PAGES/553.htm (158 words)

	Quinones increase gamma -glutamyl transpeptidase expression by multiple mechanisms in rat lung epithelial cells -- Liu ...
		Quinones increase gamma -glutamyl transpeptidase expression by multiple mechanisms in rat lung epithelial cells -- Liu et al.
		A role for gamma-glutamyl transpeptidase in the transport of cystine into human endothelial cells: relationship to intracellular glutathione.
		Measurement of gamma-glutamyl transpeptidase and gamma-glutamylcysteine synthetase activities in cells.
	ajplung.physiology.org /cgi/content/full/274/3/L330 (4425 words)

	{gamma}-Glutamyl Transpeptidase Inhibition Suppresses Milk Protein Synthesis in Isolated Ovine Mammary Cells -- ...
		Error bars indicate standard error of the means (d 0 n = 4; pregnant: d 90 n = 2, d 135 n = 6; lactating: d 14 n = 7, d 42 n = 11, where n is the number of sheep).
		-Glutamyl transpeptidase in lactating mammary secretory tissue of cow and rat.
		Lack of relationship between gamma-glutamyl transpeptidase and tyrosine transport in cultured bovine adrenal chromaffin cells.
	www.dairy-science.org /cgi/content/full/87/2/321 (4122 words)

	Arch Pediatr Adolesc Med -- Abstract: Use of gamma-glutamyl transpeptidase in the diagnosis of biliary atresia, ...
		Arch Pediatr Adolesc Med -- Abstract: Use of gamma-glutamyl transpeptidase in the diagnosis of biliary atresia, February 1981, Wright and Christie 135 (2): 134
		Use of gamma-glutamyl transpeptidase in the diagnosis of biliary atresia
		usefulness, serum gamma-glutamyl transpeptidase (GGTP) levels were measured
	archpedi.ama-assn.org /cgi/content/abstract/135/2/134 (163 words)

	Expression and regulation of gamma -glutamyl transpeptidase-related enzyme in tracheal cells -- Potdar et al. 273 (5): ...
		-Glutamyl transpeptidase is increased by oxidative stress in rat alveolar L2 epithelial cells.
		-glutamyl transpeptidase activities enhance resistance of rat lung epithelial L2 cells to quinone toxicity.
		Characterization of a third transforming growth factor B1 transcript in rat tracheal epithelial cells.
	ajplung.physiology.org /cgi/content/full/273/5/L1082 (4152 words)

	The Ectoenzyme {gamma}-Glutamyl Transpeptidase Regulates Antiproliferative Effects of S-Nitrosoglutathione on Human T ...
		The Ectoenzyme {gamma}-Glutamyl Transpeptidase Regulates Antiproliferative Effects of S-Nitrosoglutathione on Human T and B Lymphocytes -- Henson et al.
		-Glutamyl transpeptidase: cellular expression in populations of normal human mononuclear cells and patients suffering from leukemias.
		-glutamyl transpeptidase, a lymphoid cell-surface marker: relationship to blastogenesis, differentiation, and neoplasia.
	www.jimmunol.org /cgi/content/full/163/4/1845 (5797 words)

	FDA > CDRH > Database Super Search
		Kinetic Method, Gamma-Glutamyl Transpeptidase Gamma-glutamyl transpeptidase and isoenzymes test system.
		Electrophoretic, Gamma-Glutamyl Transpeptidase Isoenzymes Gamma-glutamyl transpeptidase and isoenzymes test system.
		Colorimetric Method, Gamma-Glutamyl Transpeptidase Gamma-glutamyl transpeptidase and isoenzymes test system.
	www.accessdata.fda.gov /scripts/cdrh/cfdocs/search/search.cfm?cn=7&Search_Term=862.1360 (95 words)

	Hydrogen peroxide produced during {gamma}-glutamyl transpeptidase activity is involved in prevention of apoptosis and ...
		Hydrogen peroxide produced during {gamma}-glutamyl transpeptidase activity is involved in prevention of apoptosis and maintainance of proliferation in U937 cells -- Bello et al.
		-glutamyl transpeptidase activity is involved in prevention of apoptosis and maintainance of proliferation in U937 cells
		transpeptidase activity is involved in prevention of apoptosis
	www.fasebj.org /cgi/content/abstract/13/1/69 (1020 words)

	gamma -Glutamyl Transpeptidase in Transgenic Tobacco Plants. Cellular Localization, Processing, and Biochemical ...
		-glutamyl transpeptidase activity is involved in prevention of apoptosis and maintenance of proliferation in U937 cells.
		-Glutamyl transpeptidase from kidney bean fruit: I. Purification and mechanism of action.
		-glutamyl transpeptidase in onions: evidence for in vivo role as a peptidase.
	www.plantphysiol.org /cgi/content/full/128/3/1109 (5192 words)

	An Evaluation of Gamma-Glutamyl Transpeptidase (GGT) and p30 Determination for the Identification of Semen on ...
		Newall, PJ Forensic analyst and forensic research, respectively, Centre of Forensic Sciences, Toronto, Ontario, Canada.
		The following study entails the investigation of gamma-glutamyl transpeptidase (GGT) and p30 for the identification of seminal stains in sexual assault cases.
		Author Stubbings NA, Newall PJ Title An Evaluation of Gamma-Glutamyl Transpeptidase (GGT) and p30 Determination for the Identification of Semen on Postcoital Vaginal Swabs Symposium, Committee on
	www.astm.org /JOURNALS/FORENSIC/PAGES/613.htm (230 words)

	Dexamethasone accelerates catabolism of leukotriene C4 in bronchial epithelial cells -- Zaitsu et al. 22 (1): 35 -- ...
		-glutamyl transpeptidase (GGT) and GGT-related enzyme (GGTRE) messenger ribonucleic acid (mRNA) expression in transformed human bronchial epithelial (16HBE) cells.
		-glutamyl transpeptidase gene family member, is expressed primarily in spleen.
		-glutamyl transpeptidase cDNA: comparison of hepatoma and kidney mRNA in the human and rat.
	erj.ersjournals.com /cgi/content/full/22/1/35 (2938 words)

	Active deglycosylated mammalian gamma-glutamyl transpeptidase -- Smith and Meister 8 (9): 661 -- The FASEB Journal
		Active deglycosylated mammalian gamma-glutamyl transpeptidase -- Smith and Meister 8 (9): 661 -- The FASEB Journal
		glycosylated gamma-glutamyl transpeptidases isolated from rat and pig
		G. NEEL, and G. Efficiency of homocysteine plus copper in inducing apoptosis is inversely proportional to {gamma}-glutamyl transpeptidase activity
	www.fasebj.org /cgi/content/abstract/8/9/661 (307 words)

	Pfam 20.0 : Transpeptidase (Site not responding. Last check: 2007-11-03)
		The large number of penicillin binding proteins, which are represented in this group of sequences, are responsible for the final stages of peptidoglycan biosynthesis for cell wall formation.
		The proteins synthesise cross-linked peptidoglycan from lipid intermediates, and contain a penicillin-sensitive transpeptidase carboxy-terminal domain.
		The active site serine (residue 337 in) is conserved in all members of this family PUBMED:8605631.
	pfam.wustl.edu /cgi-bin/getdesc?name=Transpeptidase (198 words)

	(WO/2001/049858) A NOVEL POLYPEPTIDE, $g(g) -GLUTAMYL TRANSPEPTIDASE 9 AND THE POLYNUCLEOTIDE ENCODING THE POLYPEPTIDE (Site not responding. Last check: 2007-11-03)
		A NOVEL POLYPEPTIDE, $g(g) -GLUTAMYL TRANSPEPTIDASE 9 AND THE POLYNUCLEOTIDE ENCODING THE POLYPEPTIDE
		The present invention discloses a novel polypeptide, $g(g)-glutamyl transpeptidase 9, the polynucleotide encoding the polypeptide and the method for producing the polypeptide by DNA recombinant technology.
		The invention also discloses the uses of the polynucleotide encoding the novel $g(g)-glutamyl transpeptidase 9.
	www.wipo.int /ipdl/IPDL-CIMAGES/view/pct/getbykey5?KEY=01/49858.010712 (326 words)

	Reproductive Defects in {gamma}-Glutamyl Transpeptidase-Deficient Mice -- Kumar et al. 141 (11): 4270 -- Endocrinology
		-glutamyl transpeptidase messenger ribonucleic acid are expressed in the adult rat testis and epididymis.
		-Glutamyl transpeptidase of rat seminal vesicles; effect of orchidectomy and hormone administration on the transpeptidase in relation to its possible role in secretory activity.
		-glutamyl transpeptidase mRNAs in the initial segment of the rat epididymis.
	endo.endojournals.org /cgi/content/full/141/11/4270 (4798 words)

	Probing the Catalytic Activity of a Cell Division-Specific Transpeptidase In Vivo with {beta}-Lactams -- Eberhardt et ...
		Probing the Catalytic Activity of a Cell Division-Specific Transpeptidase In Vivo with ß-Lactams
		Penicillin-binding assays as probes of transpeptidase catalytic activity.
		The Escherichia coli cell division protein FtsW is required to recruit its cognate transpeptidase, FtsI (PBP3), to the division site.
	jb.asm.org /cgi/content/full/185/13/3726 (6557 words)

	FDA > CDRH > Database Super Search
		21CFR862.1360 Clinical chemistry and clinical toxicology devices Gamma-glutamyl transpeptidase and isoenzymes test system.
		A gamma-glutamyl transpeptidase and isoenzymes test system is a device intended to measure...
		SPECTRUM DIAGNOSTICS GGTP TEST SYSTEM GAMMAGLUTAMYL TRANSPEPTIDASE TEST SYSTEM COLORIMETRIC METHOD, GAMMA-GLUTAMYL TRANSPEPTIDASE EGYPTIAN CO. FOR BIOTECHNOLOGY EGYPTIAN CO. FOR BIOTECHNOLOGY JPZ 86...
	www.accessdata.fda.gov /scripts/cdrh/cfdocs/search/search.cfm?Search_Term=862.1360 (148 words)

	Marie H. Hanigan's CV
		"Gamma-Glutamyl Transpeptidase and Cisplatin Sensitivity in Human Ovarian Tumors", Award $15,000
		"The Role of Gamma-Glutamyl Transpeptidase in Hepatocarcinogenesis" Grant #2448
		Peters, J., Lacaille, F., Horslen, S., Thompson, R.J., Jaffe, R., Brousse, N., Jaubert, F., Berrebi, D., Peuchmaur, M., Wisecarver, J., Knisely, A.S., and Hanigan, M.H. (2002) Microvillus Inclusions disease Treated by Small Bowel Transplantation: Development of Progressive Intrahepatic Cholestasis with Low Serum Concentrations of Gamma-Glutamyl Transpeptidase Activity.
	w3.ouhsc.edu /cell_biology/faculty/hanigancv.html (2719 words)

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