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Topic: Tranylcypromine

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Anxiety disorder

	Tranylcypromine - Definition, Purpose, Description, Recommended dosage, Precautions, Side effects, Interactions
		Tranylcypromine is used primarily to treat depression that does not respond to other types of drug therapy.
		Tranylcypromine is effective for treating depression, especially complicated types of depression that have not responded to more traditional antidepressants.
		Tranylcypromine should be used with great caution in pregnant and nursing women only after the risks and benefits of treatment have been assessed.
	www.minddisorders.com /Py-Z/Tranylcypromine.html (1102 words)

	Tranylcypromine (MAO inhibitor) (Site not responding. Last check: 2007-10-14)
		Tranylcypromine differs from the other agents in the class in that it binds reversibly to MAO while the others bind irreversibly.
		Tranylcypromine was approved by the FDA in 1961.
		Tranylcypromine is a nonselective MAOI that desensitizes alpha- and beta-adrenergic and serotonin receptors.
	www.rockford.uic.edu /jc/tranylcy.htm (335 words)

	Tranylcypromine Information on Healthline (Site not responding. Last check: 2007-10-14)
		Tranylcypromine is a monoamine oxidase inhibitor (MAOI) in the class of drugs called antidepressants.
		Tranylcypromine is used to treat the symptoms of depression such as feelings of sadness, worthlessness, or guilt; loss of interest in daily activities; changes in appetite; tiredness; sleeping too much; insomnia; and thoughts of death or suicide.
		Tranylcypromine is in the FDA pregnancy category C. This means that it is not known whether tranylcypromine will be harmful to an unborn baby.
	www.healthline.com /multumcontent/tranylcypromine (1439 words)

	Tranylcypromine - Wikipedia, the free encyclopedia (Site not responding. Last check: 2007-10-14)
		Tranylcypromine is a non-hydrazine, monoamine oxidase inhibitor, and has a rapid onset of action.
		The antidepressant activity of tranylcypromine primarily derives from its inhibition of monoamine oxidase, and the multiple reuptake inhibition of one of its metabolites.
		Tranylcypromine should not be given to patients suspected of having a cerebrovascular defect, nor to patients with cardiovascular disease.
	en.wikipedia.org /wiki/Tranylcypromine (495 words)

	MedlinePlus Drug Information: Tranylcypromine
		Children younger than 18 years of age should not normally take tranylcypromine.If your child's doctor has prescribed tranylcypromine for your child, you should watch his or her behavior very carefully, especially at the beginning of treatment and any time his or her dose is increased or decreased.
		Tranylcypromine is used to treat depression in people who have not been helped by other medications.
		Tranylcypromine is in a class of medications called monoamine oxidase inhibitors (MAOIs).
	www.nlm.nih.gov /medlineplus/druginfo/medmaster/a682088.html (1457 words)

	Psychotic and Mental Health Medications (Site not responding. Last check: 2007-10-14)
		Tranylcypromine, a non-hydrazine reversible MAO inhibitor, is indicated for the symptomatic treatment of moderate to severe depression.
		Tranylcypromine should not be used in the presence of known or suspected pheochromocytoma, as such tumors secrete pressor substances.
		Patients on tranylcypromine therapy should also be advised not to consume excessive amounts of caffeine in any form (coffee, tea, cola drinks, etc.) because of possible enhanced effects of caffeine on the CNS.
	www.support4hope.com /med_index_20.htm (1947 words)

	Index Postgrad
		Tranylcypromine is an irreversible monoamine oxidase (MAO) inhibitor used in the treatment of therapy-resistant depression and atypical depression.
		Tranylcypromine was started, and a dose of 50 mg two times a day resulted in a partial remission of the depressive symptoms.
		Tranylcypromine (‘Parnate’) overdose: measurement of tranylcypromine concentrations and MAO inhibitory activity and identification of amphetamines in plasma.
	www.antenna.nl /lithium/english/postgrad/Pennings_ep.html (1385 words)

	Order PARNATE @ Rx Care Canada
		Tranylcypromine is a nonhydrazine monoamine oxydase (MAO) inhibitor with a rapid onset of activity.
		Before prescribing tranylcypromine, the physician should be thoroughly familiar with information on its dosage, side effects and contraindications, as well as the principles of MAO inhibitor therapy and the side effects of this class of drugs as reported in the literature.
		Tranylcypromine is not recommended for patients with a history of recurring or frequent headaches, especially the tension and vascular types.
	canadadrugs.rxcarecanada.com /PARNATE.asp?prodid=PARNATE (3619 words)

	Drug Comparisons - Compare Drugs - DrugDigest (Site not responding. Last check: 2007-10-14)
		Both tranylcypromine and nortriptyline produced significant improvement in depression symptoms as compared to placebo's effectiveness, and the effectiveness of both drugs was approximately equivalent.
		Patients in the tranylcypromine group experienced slightly more side effects, however, and a disproportionally high percentage of the study participants were experiencing unusual types of depression.
		Tranylcypromine may be comparable in effectiveness to nortriptyline--especially in certain subsets of patients with depression that does not respond to treatment with other drugs.
	www.drugdigest.org /DD/Comparison/StudyEvidence/0,4063,417,00.html (177 words)

	tranylcypromine Consumer Drug Information
		Tranylcypromine is a monoamine oxidase inhibitor (MAOI) that works by increasing the levels of certain chemicals in the brain.
		While you are taking tranylcypromine you will need to be monitored for worsening symptoms of depression and/ or suicidal thoughts during the first weeks of treatment, or whenever your dose is changed.
		Tranylcypromine should not be given to a child without a doctor's advice.
	www.drugs.com /mtm/tranylcypromine.html (1979 words)

	Tranylcypromine
		Tranylcypromine is not used for the treatment of mild depression caused by external influences.
		Tranylcypromine should not be started until at least one week after a TCA or related antidepressant or a SSRI or related antidepressant has been stopped (5 weeks for fluoxetine).
		When tranylcypromine is taken with pethidine there is an increase in the incidence of life threatening side-effects occurring.
	www.netdoctor.co.uk /medicines/100003224.html (869 words)

	Parnate - Drugs & Vitamins - Drug Library - DrugDigest (Site not responding. Last check: 2007-10-14)
		Tranylcypromine increases the level of certain chemicals in the brain that help fight depression and other mood problems, including certain anxiety disorders.
		Tranylcypromine can interact with certain foods and other medicines to cause unpleasant side effects.
		Tranylcypromine can interact with certain foods that contain tyramine to produce severe headaches, a rise in blood pressure, or irregular heart beat.
	www.drugdigest.org /DD/DVH/Uses/0,3915,677\|Parnate,00.html (909 words)

	Tranylcypromine - Patient UK
		Tranylcypromine belongs to the group of antidepressant medicines known as Monoamine-Oxidase Inhibitors (MAOIs).
		Tranylcypromine is used to treat depression, especially where the patient is excitable or suffering from phobias (fears).
		Make sure you know how you react to Tranylcypromine before driving, operating machinery or doing any other jobs which could be dangerous if you were not fully alert or able to see properly.
	www.patient.co.uk /showdoc/30002829 (956 words)

	MAO Inhibitors
		Bipolar: Tranylcypromine Recommended for Resistant Depression: "Bipolar I depressions should initially be treated with a mood stabilizer (carbamazapine, divalproex, lamotrigine, lithium, or an atypical antipsychotic); antidepressant monotherapy is contraindicated.
		Phenelzine Did as Well as Tranylcypromine: In a 5-week DB PC study of 77 severely Major Depression in-patients, who failed on either tricyclic antidepressants or fluvoxamine found no significant differences between tranylcypromine and phenelzine: 44% responded on tranylcypromine vs. 47% on phenelzine.
		Efficacy and tolerability of tranylcypromine versus phenelzine: a double-blind study in antidepressant-refractory depressed inpatients.
	www.modern-psychiatry.com /new_page_23.htm (1889 words)

	Tranylcypromine
		If your child's doctor has prescribed tranylcypromine for your child, you should watch his or her behavior very carefully, especially at the beginning of treatment and any time his or her dose is increased or decreased.
		Your child's doctor will want to see your child often while he or she is taking tranylcypromine, especially at the beginning of his or her treatment.Your child's doctor may also want to speak with you or your child by telephone from time to time.
		Be sure that your child keeps all appointments for office visits or telephone conversations with his or her doctor.
	www.safemedication.com /displaydrug.cfm?id=682088 (1375 words)

	Tranylcypromine (Parnate): A guide to Tranylcypromine sulfate drug
		Tranylcypromine, a monoamine oxidase (MAO) inhibitor and an antidepressant (mood elevator), is used to treat depression.
		MAO inhibitors [phenelzine (Nardil) or tranylcypromine (Parnate)] are used occasionally to treat eating disorders, cocaine addiction, headaches, and panic attacks.
		Tranylcypromine sulfate medine and drug..know withdrawal side effects, precautions and uses.
	www.depression-guide.com /tranylcypromine.htm (751 words)

	Addiction to tranylcypromine : a case report - Parnate American Journal of Drug and Alcohol Abuse - Find Articles
		Thus, the development of increasing dosage, drug seeking, and withdrawal from tranylcypromine (Parnate) in the patient reported here were unexpected.
		Originally used in the early 1960s, tranylcypromine and other MAOI's were taken off the American market for over a decade due to life-threatening hypertension and several cases of cerebrovascular accident[8].
		At that time, tranylcypromine had also been prescribed at 40 mg daily, but was discontinued when the patient on his own increased his dose over a few weeks to 80 mg daily.
	www.findarticles.com /p/articles/mi_m0978/is_n3_v15/ai_7966787 (873 words)

	MAO inhibitors An option worth trying in treatment-resistant cases (Site not responding. Last check: 2007-10-14)
		Tranylcypromine can cause insomnia and a greater increase in tyramine sensitivity than other MAOIs, which therefore brings a greater risk of hypertensive crisis.
		A patient at McLean who had eaten cheese without trouble for 4 years while taking tranylcypromine in Europe mysteriously developed a severe headache after one bit of cheddar in the United States; she never tried an MAOI again.
		Another patient who took tranylcypromine for months at dosages exceeding 100 mg/d (but never took the tyramine restriction seriously) suffered a frightening pulsatile headache after a Chinese restaurant meal with soy sauce.
	users3.ev1.net /~drtony/MAOIs.htm (2497 words)

	Tranylcypromine/Parnate - Wheeless' Textbook of Orthopaedics
		- usual effective dose of tranylcypromine is 30 mg/day, usually given in
		- effects of tranylcypromine are observed after 10 days of treatment;
		- tranylcypromine must be used cautiously in patients receiving Tricyclics
	www.wheelessonline.com /ortho/tranylcypromine_parnate (54 words)

	PARNATE: buy parnate, discount parnate, side effects parnate - Swiftrx (Site not responding. Last check: 2007-10-14)
		Tranylcypromine can improve your mood and feelings of well-being.
		Before taking tranylcypromine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.
		Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: drugs for diabetes (e.g., glyburide, insulin), drugs for high blood pressure (e.g., beta blockers such as atenolol, clonidine, rauwolfia alkaloids such as reserpine, "water pills"/diuretics such as hydrochlorothiazide).
	www.meds4u.com /quick_search.jsp?criteria=PARNATE (1793 words)

	Anxiety Zone - Tranylcypromine
		It reversibly binds to monoamine oxidase and belongs to the monoamine oxidase inhibitor class of drugs.
		As with other MAOIs, users of tranylcypromine must adhere to rigid dietary guidelines.
		The information above is not intended for and should not be used as a substitute for the diagnosis and/or treatment by a licensed, qualified, health-care professional.
	www.anxietyzone.com /drugs/tranylcypromine.html (96 words)

	Tranylcypromine ( Parnate ) data sheet
		Tranylcypromine (Parnate) is for the treatment of major depressive episode without melancholia.
		Not a first line of therapy; is used when clients have failed to respond to other drug therapy.
		MAO Inhibitors - Concomitant use of tranylcypromine with other MAO inhibitors may cause a hypertensive crisis or severe seizures.
	psyweb.com /Drughtm/jsp/tranyl.jsp (490 words)

	One Fatal and One Nonfatal Intoxication with Tranylcypromine. Absence of ... (Site not responding. Last check: 2007-10-14)
		One Fatal and One Nonfatal Intoxication with Tranylcypromine.
		One clinical case involving the ingestion of 400 mg tranylcypromine with suicidal intention and one fatality with a suspicion of possible tranylcypromine overdose were examined.
		Consideration of the drug concentrations in the fatality in relation to the case findings and other reported data indicates the tranylcypromine overdose as the probable cause of death, despite the low blood concentration.
	www.jatox.com /abstracts/1996/sept/301-schmoldt.htm (197 words)

	Psychiatric Drugs: Tranylcypromine (Parnate)
		Also used for anxiety disorders, such as panic disorder with agoraphobia, social phobia, and obsessive-compulsive disorder.
		Tranylcypromine is associated with less weight gain, drowsiness, dry mouth, and sexual dysfunction than phenelzine.
		Tranylcypromine is more likely to cause insomnia than phenelzine.
	psychiatric-drugs.org /2006/06/tranylcypromine_parnate.html (164 words)

	Monamine Oxidase Inhibitors \| Poison Control Center - Children's Hospital of Philadelphia
		On November 13, 1987, a young woman wanting to take her life, ingested 48 tranylcypromine (Parnate®) 10 mg.
		Tranylcypromine (Parnate®) is one of four monoamine oxidase inhibitors marketed in the United States.
		Isocarboxazide, tranylcypromine and phenylzine were first introduced into psychiatry in the 1950s for use in endogenous depression.
	www.chop.edu /consumer/jsp/division/generic.jsp?id=72608 (1181 words)

	Antidepressants and the dopamine connection (Site not responding. Last check: 2007-10-14)
		Measurement of D2-like binding by receptor autoradiography, using the ligand [3H]YM-09151-2, revealed that both fluoxetine and desipramine increased D2-like binding in the nucleus accumbens shell; fluoxetine had a similar effect in the nucleus accumbens core.
		Tranylcypromine, however, had no effect on D2-like binding in the nucleus accumbens but decreased binding in the striatum.
		In micro-dialysis experiments, our data showed that levels of extracellular dopamine in the nucleus accumbens were not altered in rats treated with either fluoxetine or desipramine, but increased by tranylcypromine.
	www.biopsychiatry.com /dopamine.htm (255 words)

	tranylcypromine - Fort Lauderdale, Florida (Site not responding. Last check: 2007-10-14)
		To find a drug, look for it either by its brand name or its generic name.
		Symptoms of a tranylcypromine overdose include excitement, irritability, hyperactivity, anxiety, dizziness, fainting, weakness, insomnia, restlessness, fatigue, hallucinations, flushing, sweating, fast heartbeats, convulsions, a severe headache, coma, and death.
		Foods that have high levels of tyramine can cause a severe reaction, including a severe headache, large pupils, neck stiffness, nausea, vomiting, sweating, irregular heartbeats, chest pain, and death.
	www.browardhealth.org /110843.cfm (1407 words)

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