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Medmicro Chapter 36 Treponema pallidum subspp pertenue and endemicum are intermediate in invasiveness and cause destructive lesions in bones and soft tissues. Treponema pallidum subsp pallidum is a fastidious organism that exhibits narrow optimal ranges of pH (7.2 to 7.4), Eh (230 to240 mV), and temperature (30 to 37°C). Treponema pallidum subsp pallidum appears to lack potent toxins, and it is believed that tissue damage results from the host's cellular inflammatory response. gsbs.utmb.edu /microbook/ch036.htm   (4852 words)

Brian Hong Syphilis is an infectious disease that is caused by treponema pallidum. The bacteria treponema pallidum is exclusively a pathogen and it cannot replicate with the absence of mammalian cells. When treponema pallidum succeeds in reaching a person, the spirochetes infect the cells of the body and the axial fibrils of each of the spirochetes attach to an opposite end and wrap around the cell body, which is enclosed by an envelope. www.lcusd.net /lchs/mewoldsen/Hong.html   (531 words)

Treponema pertenue Treponema pallidum is probably the most famous of the group, being that it causes syphilis. The Treponema are helically coiled organisms having a corkscrew-like shape. Treponema have a very high lipid content, which is unusual for most bacteria. web.umr.edu /~microbio/BIO221_2000/Treponema_pertenue.html   (677 words)

Treponema   (Site not responding. Last check: 2007-11-04) Treponema are delicate organisms requiring pH in the range 7.2 to 7.4, temperatures in the range 30°C to 37°C and a microaerophilic environment. Treponema possess a complex antigenic makeup that is difficult to determine because the organisms cannot be grown in vitro. Treponema pallidum is capable of infecting all body tissues. www.cehs.siu.edu /fix/medmicro/trepo.htm   (834 words)

Treponemapallidum Treponema pallidum is the causative agent of the sexually transmitted disease Syphilis. Treponema pallidum is transmitted from one infected person to another. In 1998, scientists succuessfully sequenced the genome of the bacteria Treponema pallidum. www.treponemapallidum.homestead.com   (1010 words)

Title of Invention: Treponema hyodysenteriae vaccin e The present invention is concerned with vaccine for combating Treponema hyodysenteriae infection in swine containing proteins or polypeptides typical of the hemolysin protein of Treponema hyodysenteriae or containing recombinant polynucleotides having as part thereof a polynucleotide coding for said protein or polypeptide, and also is concerned with the preparation of said proteins, polypeptides and polynucleotides. The present invention is concerned with a vaccine for combating Treponema hyodysenteriae infection and with recombinant polynucleotides and polypeptides for the preparation of such a vaccine. Treponema hyodysenteriae, the etiological agent of swine dysentery is an anaerobic, beta-hemolytic spirochete found in the porcine large intestine. www.nal.usda.gov /bic/Biotech_Patents/1994patents/05364774.html   (6409 words)

Treponema pallidum Surface Immunofluorescence Assay for Serologic Diagnosis of Syphilis -- Marangoni et al. 7 (3): 417 ...   (Site not responding. Last check: 2007-11-04) Treponema pallidum Surface Immunofluorescence Assay for Serologic Diagnosis of Syphilis -- Marangoni et al. Treponema pallidum Surface Immunofluorescence Assay for Serologic Diagnosis of Syphilis Characterization of outer membranes isolated from Treponema pallidum, the syphilis spirochete. cdli.asm.org /cgi/content/full/7/3/417   (2863 words)

Recombinant Treponema Pallidum Lipoprotein Immunogen p47 - TRP-243   (Site not responding. Last check: 2007-11-04) Virulent Treponema pallidum 47 kDa antigen regulates the expression of cell adhesion molecules and binding of T-lymphocytes to cultured human dermal microvascular endothelial cells. The 47-kDa major lipoprotein immunogen of Treponema pallidum is a penicillin-binding protein with carboxypeptidase activity. Analysis of the N-terminal region of the 47-kilodalton integral membrane lipoprotein of Treponema pallidum. www.prospec.co.il /~prospec/cart/catalog/rTRPp47.html   (212 words)

eMedicine - Treponematosis (Endemic Syphilis) : Article Excerpt by: Steven Fine, MD, PhD Background: Treponematosis traditionally refers to the group of nonvenereal diseases that are caused by Treponema species that are morphologically and serologically identical to each other and to Treponema pallidum subspecies pallidum, the cause of syphilis. All the nonvenereal Treponema species are transmitted, chiefly by direct contact, among children living in tropical and subtropical climates. In humans, the pathogenic treponemes are T pallidum pallidum, Treponema pertenue (yaws), Treponema endemicum (bejel or endemic syphilis), and Treponema carateum (pinta). www.emedicine.com /med/byname/treponematosis-(endemic-syphilis).htm   (589 words)

Specialty Laboratories ::: we help doctors help patients Molecular analysis of the fetal IgM response to Treponema pallidum antigens: implications for improved serodiagnosis of congenital syphilis. Pathology of the umbilical cord in congenital syphilis: analysis of 25 specimens using histochemistry and immunofluorescent antibody to Treponema pallidum. The immune response to infection with Treponema pallidum, the stealth pathogen. www.specialtylabs.com /books/print_view.asp?id=455   (2416 words)

Polypeptides of Treponema pallidum: progress toward understanding their structural, functional, and immunologic roles. ...   (Site not responding. Last check: 2007-11-04) Polypeptides of Treponema pallidum: progress toward understanding their structural, functional, and immunologic roles. Stamm, L. V., Bergen, H. The Sequence-Variable, Single-Copy tprK Gene of Treponema pallidum Nichols Strain UNC and Street Strain 14 Encodes Heterogeneous TprK Proteins. Marangoni, A., Sambri, V., Storni, E., D'Antuono, A., Negosanti, M., Cevenini, R. Treponema pallidum Surface Immunofluorescence Assay for Serologic Diagnosis of Syphilis. mmbr.asm.org /cgi/content/abstract/57/3/750   (873 words)

Phenotypic and Genotypic Heterogeneity among Cultivable Pathogen-Related Oral Spirochetes and Treponema vincentii -- ...   (Site not responding. Last check: 2007-11-04) vincentii-specific PCR, and one was amplified by Treponema Use of monoclonal antibodies to enumerate spirochetes and identify Treponema denticola in dental plaque of children, adolescents and young adults. Antibodies to Treponema pallidum in serum from subjects with periodontitis: relationship to pathogen-related oral spirochetes. jcm.asm.org /cgi/content/full/37/11/3676   (2933 words)

Antibody Datasheet (Spirochete - Treponema Pallidum)   (Site not responding. Last check: 2007-11-04) Spirochete, Treponema Pallidum, is the causative agent of syphilis. In the past, localization of the spirochete agent was achieved with silver stains such as Steiner’s and/or Warthin-Starry. Treponema Pallidum can now be successfully localized with immunohistochemical techniques in formalin-fixed paraffin-embedded tissue. www.biocare.net /AntibodyView.asp?ID=420   (85 words)

Medical Dictionary: Treponema pallidum - WrongDiagnosis.com Treponema pallidum: Another name for Syphilis (or close medical condition association). Treponema pallidum: Treponema pallidum is listed as a type of (or associated with) the following medical conditions in our database: Sexually Transmitted Diseases, Bacterial diseases, Diseases contagious from sex, Diseases contagious from vaginal sex, Vagina conditions Treponema pallidum (medical condition): Rare sexually transmitted bacterial disease. Treponema pallidum: Syphilis, once a cause of devastating epidemics, can be effectively diagnosed and treated with antibiotic therapy. www.wrongdiagnosis.com /medical/treponema_pallidum.htm   (244 words)

A flagellar gene cluster from the oral spirochaete Treponema maltophilum -- Heuner et al. 146 (2): 497 -- Microbiology   (Site not responding. Last check: 2007-11-04) A flagellar gene cluster from the oral spirochaete Treponema maltophilum -- Heuner et al. A flagellar gene cluster from the oral spirochaete Treponema maltophilum A flagellar gene cluster from the oral spirochaete Treponema mic.sgmjournals.org /cgi/content/abstract/146/2/497   (213 words)

DermAtlas: Online Dermatology Image Library dermatology image,syphilis, secondary,syphilis, Treponema ...   (Site not responding. Last check: 2007-11-04) Treponema pallidum was identified from the oral lesions by polymerase chain reaction. A few months later his daughter was evaluated for a primary lesion on her lip. Screening for sexually transmitted diseases revealed posite HIV titers; a positive RPR with a titer of 1/128, a reactive Treponema pallidum microhemagglutination assay, a positive Human immunodeficiency test, and positive pregnancy test. dermatlas.med.jhmi.edu /derm/result.cfm?Diagnosis=1596362672   (809 words)

Treponema brennaborense sp. nov., a novel spirochaete isolated from a dairy cow suffering from digital dermatitis -- ...   (Site not responding. Last check: 2007-11-04) A novel Treponema species was isolated from an ulcerative lesion of a cow Treponema brennaborense is proposed, is designated the type strain of the Treponema maltophilum, an oral spirochaete isolated from a periodontitis ijs.sgmjournals.org /cgi/content/abstract/49/1/43   (566 words)

Transcriptome of Treponema pallidum: Gene Expression Profile during Experimental Rabbit Infection -- Smajs et al. 187 ...   (Site not responding. Last check: 2007-11-04) Transcriptome of Treponema pallidum: Gene Expression Profile during Experimental Rabbit Infection -- Smajs et al. Treponema pallidum major sheath protein homologue TprK is a target of opsonic antibody and the protective immune response. The genome of Treponema pallidum: new light on the agent of syphilis. jb.asm.org /cgi/content/full/187/5/1866   (3096 words)

Treponema Schaudinn 1905, genus KINYON (J.M.) and HARRIS (D.L.): Treponema innocens, a new species of intestinal bacteria and emended description of the type strain of Treponema hyodysenteriae Harris et al. STANTON (T.B.), JENSEN (N.S.), CASEY (T.A.), TORDOFF (L.A.), DEWHIRST (F.E.) and PASTER (B.J.): Reclassification of Treponema hyodysenteriae and Treponema innocens in a new genus, Serpula gen. nov., as Serpula hyodysenteriae comb. SMIBERT (R.M.) and BURMEISTER (J.A.): Treponema pectinovorum sp. www.bacterio.cict.fr /bacterio/t/treponema.html   (1455 words)

New Products   (Site not responding. Last check: 2007-11-04) This protein binds to murine anti-TP 15kD protein monoclonal antibodies and Treponema pallidum converted human serum polyclonal antibodies in ELISA and Western Elisa. This protein binds to murine anti-TP 17kD protein monoclonal antibodies and Treponema pallidum converted human serum polyclonal antibodies in ELISA and Western Elisa. This protein binds to murine anti-TmpA protein monoclonal antibodies and Treponema pallidum converted human serum polyclonal antibodies in ELISA and Western Elisa. www.immunodx.com /newproducts.html   (320 words)

Treponema pallidum   (Site not responding. Last check: 2007-11-04) Treponema pallidum is the causative agent of syphilis, a sexually transmitted disease (STD). Other bacteria in the same genus cause the diseases yaws and bejel, which are transmitted through direct skin-to-skin contact or sharing of drinking vessels. Very tight coils are seen in Leptospira, medium coils in Treponema and open coils are seen in Borrelia. www-micro.msb.le.ac.uk /video/Tpallidum.html   (813 words)

Identification of Seven Treponema Species in Health- and Disease-Associated Dental Plaque by Nested PCR -- Willis et ...   (Site not responding. Last check: 2007-11-04) Identification of Seven Treponema Species in Health- and Disease-Associated Dental Plaque by Nested PCR -- Willis et al. Plaque treponemas are associated with periodontal diseases (6), but detection of individual species has been limited by The number of treponema species detected ranged from zero to five species/sample of HH plaque to two to seven species/sample jcm.asm.org /cgi/content/full/37/3/867   (1390 words)

Treponema pallidum Particle Agglutination Testing (TPPA) - Serology Testing Services - Public Health Laboratory - ...   (Site not responding. Last check: 2007-11-04) Treponema pallidum Particle Agglutination Testing (TPPA) - Serology Testing Services - Public Health Laboratory - Public Health Division - Dept. of Health Services - County of Sonoma, CA Public Health Home Treponema pallidum Particle Agglutination Testing (TPPA) is used to detect antibodies to the various species and subspecies of pathogenic Treponema, including the cansitive agent of syphilis, Treponema pallidum. Treponema pallidum Particle Agglutination Testing (TPPA) is FDA approved for serum and plasma specimens. www.sonoma-county.org /health/ph/laboratory/s_tppa.htm   (172 words)

ARUP: Treponema pallidum (VDRL), Serum with Reflex to Titer ARUP: Treponema pallidum (VDRL), Serum with Reflex to Titer Treponema pallidum (VDRL), Serum with Reflex to Titer 0093093: Treponema pallidum (VDRL), Serum with Reflex to Titer www.aruplab.com /guides/ug/tests/0093093.jsp   (101 words)

Treponema pallidum   (Site not responding. Last check: 2007-11-04) The Treponema pallidum circular genome of 1.138 Mb was sequenced in 1998 by teams at The Institute for Genomic Research (TIGR) and the University of Texas at Houston, working under the aegis of the STD Branch, NIAID/NIH. The key publication describing this newly sequenced genome is "Complete Genome Sequence of Treponema pallidum, the Syphilis Spirochete" by C.M. Fraser, S.J. Norris, G.M. Weinstock and colleagues, Science 281:375-388, 1998. Approximately 300 additional references pertaining to Treponema species can be extracted from the Molecular Subset of MEDLINE (T.pallidum References). www.stdgen.lanl.gov /stdgen/bacteria/t_pal   (276 words)

Protracted Treponema pallidum-induced cutaneous chancres in rabbits infected with human T-cell leukemia virus type I. Protracted Treponema pallidum-induced cutaneous chancres in rabbits infected with human T-cell leukemia virus type I. Important note: Information in this article was accurate in 1991. Protracted Treponema pallidum-induced cutaneous chancres in rabbits infected with human T-cell leukemia virus type I. AIDS Res Hum Retroviruses. Six months after infection, the four HTLV-infected rabbits and two noninfected controls were challenged by the intradermal inoculation of 1 x 10(6) Treponema pallidum into eight sites on the shaved back. www.aegis.com /aidsline/1991/oct/M91A0704.html   (454 words)

Explore the Microscopic World of Health Science   (Site not responding. Last check: 2007-11-04) Treponema pallidum subspecies pallidum is the causative agent of syphilis; except for congenital syphilis, sexual contact accounts for virtually all cases of the disease. Light microscope pictures showing tissue infected with the spirochete Treponema pallidum, the causative agent of syphilis. The left micrograph shows cell infiltration in the tissue; on the right spirochetes visualized by silver staining. www.wadsworth.org /databank/treponem.htm   (94 words)

Systematic Cloning of Treponema pallidum Open Reading Frames for Protein Expression and Antigen Discovery -- McKevitt ...   (Site not responding. Last check: 2007-11-04) Individual GST-fusion Treponema pallidum proteins from crude Escherichia coli extracts were selectively immobilized on glutathione-coated 96-well plates and were exposed to rabbit serum from rabbits either before or 2 months after intratesticular injection with virulent T. Champion, C.I., Miller, J.N., Borenstein, L.A., Lovett, M.A., and Blanco, D.R. Immunization with Treponema pallidum endoflagella alters the course of experimental rabbit syphilis. Radolf, J.D., Robinson, E.J., Bourell, K.W., Akins, D.R., Porcella, S.F., Weigel, L.M., Jones, J.D., and Norgard, M.V. Characterization of outer membranes isolated from Treponema pallidum, the syphilis spirochete. www.genome.org /cgi/content/full/13/7/1665   (5328 words)

Biology 216 - Treponema   (Site not responding. Last check: 2007-11-04) Syphilis - Treponema pallidum - Spirochete, 3 stages, penetrate between cells... TPHA: RBC w/ treponema coating + serum -> HA FTA (fluoresecent treponemal Ab): IFA using serum absorbed w/Reiter strain (FTA-ABS) to remove group Ag (to normal flora treponemes) D. Treatment - Penicillin for primary or secondary (become reagin negative in one year) Jarisch-Herxheimer - Therapeutic shock - flu-like due to sudden release of Ag (24 hours later) Due to LPS release, IL-1, TNF. www.csuchico.edu /biol/personnel/Hanne/MedBactNotes/Lect31Treponema.html   (520 words)

The TprK Protein of Treponema pallidum Is Periplasmic and Is Not a Target of Opsonic Antibody or Protective Immunity -- ...   (Site not responding. Last check: 2007-11-04) Stebeck, C.E., Shaffer, J.M., Arroll, T.W., Lukehart, S.A., and Van Voorhis, W.C. Identification of the Treponema pallidum susp. Neelaredoxin, an iron-binding protein from the syphilis spirochete, Treponema pallidum, is a superoxide reductase. Tpr Homologs in Treponema paraluiscuniculi Cuniculi A Strain www.jem.org /cgi/content/full/193/9/1015   (6431 words)

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