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Topic: Trichloroacetic acid

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	TRICHLOROACETIC ACID
		The half-life of trichloroacetic acid, given orally or formed as a metabolite of trichloroethylene or trichloroethanol, is longer in humans than in rodents.
		In male mice, trichloroacetic acid modified neither the incidence of mutations in exon 2 of H-ras in carcinomas, nor the mutational spectrum observed in tumours that bore a mutation in exon 2.
		Trichloroacetic acid induced abnormal sperm in mice in vivo in one study and chromosomal aberrations in mouse and chicken bone marrow in vivo.
	www.inchem.org /documents/iarc/vol84/84-05-trichl.html (620 words)

	Glossary: Trichloroacetic acid
		Inhalation of trichloroacetic acid vapour may lead to a sore throat and cause fluid to fill the lungs (pulmonary oedema).
		Trichloroacetic acid is used as a laboratory reagent but its main use is in the production of its sodium salt, which is used in many industries, for example, as a herbicide, etching agent and antiseptic.
		In the environment, very small quantities of trichloroacetic acid are found in chlorinated drinking water as a disinfection by product as a consequence of the reaction of chlorine with natural organic matter and bromide ions in the raw water supply (from lake, reservoirs, rivers, etc.).
	www.greenfacts.org /glossary/tuv/trichloroacetic-acid.htm (195 words)

	Better Complexions - TCA Trichloroacetic acid chemical peels
		Trichloroacetic Acid (TCA) Peels, often called “freshening peels”, are chemical peels that have been used for many years to remove the buildup of dead skin cells.
		Trichloroacetic acid peels can be performed in a doctor’s office and can range anywhere from $350 and $3,000 in cost depending upon who does the peel (technician or surgeon), the strength and span of the TCA chemical peel.
		Trichloroacetic acid peels, while most commonly used on the face, can also be used where you have other signs of aging and sun damage like the neck, arms, hands and chest.
	www.bettercomplexions.com /TCA-Trichloroacetic-acid-peels.htm (1705 words)

	Trichloroacetic acid (CASRN 76-03-9), IRIS, Environmental Protection Agency
		Dichloroacetic acid (DCA), carbon dioxide and an unidentifiable group of nonchlorinated acids are formed in Fischer 344 rats and B6C3F1 mice after administration of a single gavage dose of 20 or 100 mg/kg TCA (Bull et al., 1993; Larson and Bull, 1992).
		Liver tumor induction in B6C3F1 mice by dichloroacetate and trichloroacetate.
		The carcinogenicity of trichloroethylene and its metabolites, trichloroacetic acid and dichloroacetic acid, in mouse liver.
	www.epa.gov /iris/subst/0655.htm (3206 words)

	Trichloroacetic acid - Wikipedia, the free encyclopedia
		Trichloroacetic acid (also known as trichloroethanoic acid) is an analogue of acetic acid in which the three hydrogen atoms of the methyl group have all been replaced by chlorine atoms.
		It is prepared by the reaction of chlorine with acetic acid in the presence of a suitable catalyst.
		Solutions containing trichloroacetic acid as an ingredient are used for tattoo removal and the treatment of warts, including genital warts.
	en.wikipedia.org /wiki/Trichloroacetic_acid (203 words)

	Trichloroacetic Acid (IARC Summary & Evaluation, Volume 63, 1995) (Site not responding. Last check: 2007-10-10)
		Trichloroacetic acid is produced commercially in small amounts by chlorination of acetic or chloroacetic acid.
		Trichloroacetic acid was tested by oral administration in the drinking-water in two studies in males of one strain of mice.
		Trichloroacetic acid induced chromosomal aberrations and abnormal sperm in mice in one study.
	www.inchem.org /documents/iarc/vol63/trichloroacetic-acid.html (406 words)

	TCA Chemical Peel - Instructions for using Trichloroacetic acid peel kits at home
		The Trichloroacetic Acid (TCA) Peel, a medium peel, is one of the gold standards for treatment of fine wrinkling of the skin.
		Trichloroacetic acid treatments can be used in varying concentrations from as low as 10% to as high as 50% -- The higher the concentration, the deeper the peel.
		With trichloroacetic acid peels, scarring and brown discoloration of the skin is unlikely unless the client goes to a tanning salon after having the treatment or lies out in the sun.
	www.tcapeels.com /how-to-use-a-tcapeel-at-home.htm (1529 words)

	eMedicine - Skin Resurfacing: Chemical Peels : Article by Don R Revis, Jr, MD (Site not responding. Last check: 2007-10-10)
		The typical alpha hydroxy acid (AHA) peel involves the use of glycolic acid, which is derived from sugar cane, at concentrations of 50% or higher.
		Over-the-counter AHA products containing 3-10% glycolic acid or other naturally occurring organic acids (lactic acid, citric acid, tartaric acid, malic acid) cause exfoliation over several weeks and actually may be used as a pre-peel primer to potentiate the effects of application of a higher concentration.
		Instruct patients not to reapply transretinoic acid, sunscreen, or makeup until the face is healed to the satisfaction of the treating physician.
	www.emedicine.com /ent/topic625.htm (3883 words)

	TCA Peels - Chemical Cosmetic Skin Peels for in home use
		Trichloroacetic Acid is the same chemical that Cosmetic surgeons use for peels.
		Trichloroacetic acid (TCA) is typically used as an intermediate-to-deep peeling agent in concentrations of 10 to 35%.
		Trichloroacetic acid is for professional use only; Use at your own risk.
	www.tcapeel.net (923 words)

	RemedyFind: patient ratings of Chemical Peels: Trichloroacetic Acid (TCA) for Skin Care (Site not responding. Last check: 2007-10-10)
		Trichloroacetic acid (TCA) is typically used as an intermediate-to-deep peeling agent in concentrations ranging from 20-50%.
		Trichloroacetic acid (TCA) is the most popular peeling agent used in different concentrations.
		Seventy percent glycolic acid gel was applied to the areas to be peeled, then immediately augmented with 40% TCA.
	www.remedyfind.com /treatments/138/2675 (1119 words)

	eMedicine - Burns, Chemical : Article by Robert D Cox, MD, PhD (Site not responding. Last check: 2007-10-10)
		Sulfuric acid is commonly used in toilet bowl cleaners, drain cleaners, metal cleaners, automobile battery fluid, munitions, and fertilizer manufacturing.
		Hydrochloric acid is commonly used in toilet bowl cleaners, metal cleaners, soldering fluxes, dye manufacturing, metal refining, plumbing applications, swimming pool cleaners, and laboratory chemicals.
		Trichloroacetic acid is used in laboratories and in chemical manufacturing.
	www.emedicine.com /emerg/topic73.htm (5154 words)

	Effect of Trichloroethylene and Its Metabolites, Dichloroacetic Acid and Trichloroacetic Acid, on the Methylation and ...
		Odum, J., Green, T., Foster, J. R., and Hext, P. The role of trichloroacetic acid and peroxisome proliferation in the differences in carcinogenicity of perchloroethylene in the mouse and rat.
		Pereira, M. Carcinogenic activity of dichloroacetic acid and trichloroacetic acid in the liver of female B6C3F1 mice.
		Styles, J. A., Wyatt, I., and Coutts, C. Trichloroacetic acid: Studies on uptake and effect on hepatic DNA and liver growth in mouse.
	toxsci.oxfordjournals.org /cgi/content/full/54/2/399 (6068 words)

	Trichloroacetic acid or bichloroacetic acid for genital warts (human papillomavirus) - [Medication] (Site not responding. Last check: 2007-10-10)
		Trichloroacetic acid or bichloroacetic acid for genital warts (human papillomavirus)
		Trichloroacetic acid (TCA) and bichloroacetic acid (BCA) kill genital warts by destroying the proteins in the cells.
		If the acid burns too deeply, you may have pain, skin irritation, and ulcers.
	www.bsneny.com /kbase/topic/detail/drug/hw103761/detail.htm (393 words)

	Chemical Peel Wins by Nose for Facial Skin Lesions - CME Teaching Brief® - MedPage Today
		Explain to interested patients that this study suggested a chemical peel with trichloroacetic acid may be better tolerated by patients than laser resurfacing or topical agents for removal of actinic keratoses.
		"Notable, though, is the nearly 40-fold lower rate of subsequent non-melanoma skin cancers in the trichloroacetic acid arm compared with the control population and that significant difference existed between each treatment group and the control," the authors said.
		A larger study comparing trichloroacetic acid with laser resurfacing "would help validate the superiority of this resurfacing technique over the carbon dioxide laser" and determine its cost-effectiveness compared with other treatments, they added.
	www.medpagetoday.com /Dermatology/SkinCancer/tb/3972 (777 words)

	Reductive Dehalogenation of Trichloroacetic Acid by Trichlorobacter thiogenes gen. nov., sp. nov. -- De Wever et al. 66 ...
		Reductive Dehalogenation of Trichloroacetic Acid by Trichlorobacter thiogenes gen. nov., sp.
		Trichloroacetic acid (TCA) is an industrial chemical that is found in nature mainly through its use as a herbicide against
		Microbial decomposition of halogenated propionic and acetic acids.
	aem.asm.org /cgi/content/full/66/6/2297 (3329 words)

	Amino Acid Analysis (Site not responding. Last check: 2007-10-10)
		A common method of deproteinization is protein precipitation by TCA (trichloroacetic acid) followed by ethyl acetate or ether extraction of the residual TCA.
		Amino acid elution is accomplished by using a two buffer system; initially eluting with 0.2 N sodium citrate, pH 3.28 followed by 1.0 N sodium citrate, pH 7.4.
		Derivatized amino acids are quantitated by their absorption at 570nm wavelength, except for glutamic acid and proline, which are detected at 440nm wavelength.
	wmriokc001.ouhsc.edu /amino.htm (325 words)

	Koebner phenomenon in xanthelasma after treatment with trichloroacetic acid
		With a clinical diagnosis of xanthelasma, during the last year she had been treated with five monthly topical applications of trichloroacetic acid 33 percent (TCA).
		Topically applied dichloroacetic and trichloroacetic acid are described in the literature for the treatment of xanthelasma.
		Typically, the technique involves painting the lesions using a cotton-tipped applicator in a circular fashion with the greatest amount of acid applied at the margin of the lesions [6].
	dermatology.cdlib.org /122/case_presentations/xanthelasma/toosi.html (825 words)

	Therapeutic Effect of Topical Applications of Trichloroacetic Acid for Vaginal Intraepithelial Neoplasia after ...
		Detection with the polymerase chain reaction of human papillomavirus DNA in condylomata acuminata treated in vitro with liquid nitrogen, trichloroacetic acid, and podophyllin.
		Single application treatment of human papillomavirus infection of the cervix and vagina with trichloroacetic acid: a randomized trial.
		Depths of chemexfoliation induced by various concentrations and application techniques of trichloroacetic acid in a porcine model.
	jjco.oxfordjournals.org /cgi/content/full/35/11/651 (2095 words)

	Trichloroacetic acid, sodium salt - toxicity, ecologicial toxicity and regulatory information
		Trichloroacetic acid, sodium salt - Identification, toxicity, use, water pollution potential, ecological toxicity and regulatory information
		Chemical Identification and Use for Trichloroacetic acid, sodium salt
		Quickview Toxicity Summary for Trichloroacetic Acid from U.S. EPA IRIS Database
	www.pesticideinfo.org /Detail_Chemical.jsp?Rec_Id=PC34626 (821 words)

	PLASMA BINDING OF TRICHLOROACETIC ACID IN MICE, RATS, AND HUMANS UNDER CANCER BIOASSAY AND ENVIRONMENTAL EXPOSURE ...
		Trichloroacetic acid (TCA), a mouse liver carcinogen, is a drinking
		Bull RJ (2000) Mode of action of liver tumor induction by trichloroethylene and its metabolites, trichloroacetate and dichloroacetate.
		Templin MV, Parker JC, and Bull RJ (1993) Relative formation of dichloroacetate and trichloroacetate from trichloroethylene in male B6C3F1 mice.
	dmd.aspetjournals.org /cgi/content/full/31/10/1203 (3213 words)

	EWG Investigation \| U.S. Tap Water Quality Database (Site not responding. Last check: 2007-10-10)
		Potential health impacts associated with Trichloroacetic acid include cancer, gastrointestinal or liver toxicity, respiratory toxicity, and skin sensitivity.
		An Environmental Working Group analysis of Trichloroacetic acid tests reported by 2,514 public water suppliers in 22 states shows that between 1998 and 2003, 39.0 million people in 1,749 communities drank water contaminated with Trichloroacetic acid.
		The enforceable standard which defines the highest level of a contaminant that is allowed in drinking water.
	www.ewg.org /tapwater/contaminants/contaminant.php?contamcode=2452 (560 words)

	Visual Changes Skin Care
		It is formulated with Azelaic Acid, Salicylic Acid, Lactic Acid, Kojic Acid, Mulberry Root, Bearberry (Arbutin), Licorice, Echinacea, and Gotu kola.
		It is formulated with TCA, Azelaic Acid, Salicylic Acid, Lactic Acid, Kojic Acid, Mulberry Root, Bearberry (Arbutin), Licorice, Echinacea and Gotu Kola.
		It is formulated with Pure Honey (20% Lactic Acid), Queen of the Meadow Extract-(12% Salicylic Acid).
	www.visualchanges.com /designerpeels3.html (943 words)

	Trichloroacetic Acid Peels
		These are naturally occurring acids found in fruits and other foods.
		Alpha hydroxyacids have proven to be effective in treating dry skin, acne, liver or sun spots, lessening fine facial wrinkles, decreasing pore size, and improving skin texture.
		With trichloroacetic acid peels, scarring and brown discoloration of the skin is unlikely unless you go to a tanning salon after having the treatment or lie out in the sun.
	www.skinsite.com /info_tca_peels.htm (1127 words)

	TCA Peel best skin peel - the best medical grade TCA peel skin peel available. - ESTHETICIAN'S CHOICETM MEDICAL GRADE ...
		Trichloroacetic acid TCA peels are the best, most effective non-prescription medium to deep skin peel and skin care treatment on the market! And the best thing is immediate results!
		See our recent articles and international press releases that have been published in thousands of medical reviews and other major publications and backed by plastic surgeons and doctors.
		Trichloroacetic acid (TCA) is the same active ingredient in Obagi TCA Blue Peel medium to deep skin peel treatments (the popular skin peel you've probably seen on TV on Dr. 90210, MTV's Made, and the Swan). Esthetician's Choice
	www.bestskinpeel.com (732 words)

	Protocol for Trichloroacetic Acid (TCA) Precipitation
		TCA precipitates nucleic acid polymers longer than ~20 nucleotides and can therefore be used to separate radiolabeled nucleotides incorporated into nucleic acid from unincorporated label.
		In the protocol, nucleic acid synthesis reactions are carried out in the presence of a radiolabeled nucleotide (e.g.,
		Add 2 ml of cold 10% TCA (trichloroacetic acid) to the 12 X 75 mm tube containing the remaining 100 µl diluted DNA/RNA.
	www.ambion.com /techlib/misc/tcapptn.html (477 words)

	Focal Treatment of Acne Scars with Trichloroacetic Acid: Chemical Reconstruction of Skin Scars Method
		Focal Treatment of Acne Scars with Trichloroacetic Acid: Chemical Reconstruction of Skin Scars Method
		We suggest a technique consisting of the focal application of higher trichloroacetic acid (TCA) concentrations by pressing hard on the entire depressed area of atrophic acne scars.
		This technique is called chemical reconstruction of skin scars (CROSS) by the authors.
	www.cosmeticskin.com /skin-acne4.shtml (1868 words)

	Safety (MSDS) data for trichloroacetic acid
		Synonyms: trichloroethanoic acid, aceto-caustin, amchem grass killer, konesta, varitox
		The generation of these gases in a sealed container may lead to a pressure rise sufficient to cause the container to explode.
		Solutions of trichloroacetic acid at concentrations below 30% should therefore not be stored for long periods, but disposed of immediately after use.
	ptcl.chem.ox.ac.uk /MSDS/TR/trichloroacetic_acid.html (328 words)

	Trichloroacetic Acid Paste APF (Upton's Paste)
		Additional information: Trichloroacetic acid is a caustic agent whilst salicylic acid is a keratolytic.
		Thus, this preparation removes the hyperkeratotic areas and destroy the underlying epidermis.
		Precautions for use: Trichloroacetic acid is highly caustic and this preparation may be irritating.
	www.medicineau.net.au /columns/apothecary/uptons.html (200 words)

	Cardiogenic Effects of Trichloroethylene and Trichloroacetic Acid Following Exposure during Heart Specification of ...
		Cardiogenic Effects of Trichloroethylene and Trichloroacetic Acid Following Exposure during Heart Specification of Avian Development -- Drake et al.
		Cardiogenic Effects of Trichloroethylene and Trichloroacetic Acid Following Exposure during Heart Specification of Avian Development
		Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues.
	toxsci.oxfordjournals.org /cgi/content/short/94/1/153?rss=1 (391 words)

	Glyderm Physician AccuPeel® TCA Procedure (Trichloroacetic Acid 16%): Melbourne Dermatology Skin Care
		File Glyderm Physician AccuPeel® TCA Procedure (Trichloroacetic Acid 16%) for reference.
		AccuPeel® TCA is not a substitute for a face-lift or dermabrasion.
		It is a formulation of trichloroacetic acid, a therapeutic skin rejuvenating agent.
	www.treatment-skincare.com /Glyderm/Physician-TCA.html (254 words)

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