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	Triple test - Wikipedia, the free encyclopedia
		The triple test, also called triple screen, the Kettering test or the Bart's test, is an investigation performed during pregnancy (usually the second trimester) for fetal trisomy 21 (Down syndrome).
		The test is for screening, not for diagnosis, and does not have nearly the same predictive power of amniocentesis or chorionic villus sampling.
		However, the screening test carries a much lower risk to the fetus, and in conjunction with the age-related risk by the patient is useful to indicate the need to procede to the more invasive tests.
	en.wikipedia.org /wiki/Triple_test (255 words)

	The Second Trimester of Pregnancy: Checkups & Tests Information on Healthline
		Screening the blood through the triple screen test lowers the detection rate to 85 to 90%, but it is not associated with the same complications as invasive methods.
		Falsely abnormal triple screening may be explained by wrong gestational age, multiple gestation (such as twins), vaginal bleeding in the first trimester, or fetal demise.
		Similar to the triple screen, this is a screening test and is not diagnostic.
	www.healthline.com /yodocontent/pregnancy/second-trimester-checkups-tests.html (3024 words)

	Triple Screen Prenatal Test - OhioHealth
		Triple screen is a screening test performed in the second trimester of pregnancy that helps determine the mother’s risk of carrying a baby with open neural tube defects, Down syndrome or trisomy 18.
		Triple screen is a blood test done between 15 to 20 weeks of pregnancy.
		Triple screen looks for certain patterns of these chemical levels that are associated with risks of open neural tube defects, Down syndrome or trisomy 18.
	www.ohiohealth.com /bodymaternity.cfm?id=1251 (285 words)

	What Is the Triple Screen Test? (Site not responding. Last check: 2007-11-03)
		For the screening, a sample of blood is drawn from the mother to measure three basic things: the levels of hCG (human chorionic gonadotropin) and estriol, which are produced by the placenta, and the level of alpha-fetoprotein (AFP), which is produced by the fetus.
		In determining the results of the test, doctors take into account the mother's age, weight, and ethnicity; if she is diabetic; if she is having twins or other multiples; and the gestational age of the fetus.
		If a woman's triple screen results reveal low levels of AFP and high levels of estriol and hCG, she has an increased risk of having a baby with Down syndrome.
	kidshealth.org /parent/system/medical/triple_screen.html (550 words)

	Antenatal Testing - Definition, Purpose, Description, Risks, Parental concerns
		Various tests are administered over the course of pregnancy to determine if the mother has any health conditions that may interfere with normal development of the fetus or if the fetus has any health conditions that may affect the baby's quality of life.
		What tests are ordered depends on the stage of pregnancy, the age and health of the mother, the medical history of both parents, and the family's background or ethnicity.
		Screening tests tend to be less invasive and indicate the possibility of a certain genetic disorder or birth defect but do not determine with certainty that the abnormality exists.
	www.healthofchildren.com /A/Antenatal-Testing.html (2039 words)

	Encyclopedia :: encyclopedia : Pregnancy (Site not responding. Last check: 2007-11-03)
		The beginning of pregnancy may be detected in a number of ways, including various pregnancy tests which detect hormones generated by the newly-formed placenta.
		Home pregnancy tests are personal urine tests, which normally can't detect a pregnancy until at least 12-15 days after conception.
		An accurate date of conception is important, because it is used in calculating the results of various prenatal tests (for example, in the triple screen test).
	www.hallencyclopedia.com /Pregnancy (1455 words)

	AFP Testing (Site not responding. Last check: 2007-11-03)
		The AFP test is a blood test which is done when a woman is between 16 and 18 weeks pregnant.
		The AFP screening test identifies women who may be further along, or not as far along, in their pregnancy as they thought.
		The test can also identify women who are carrying a fetus with a neural tube defect, or other severe birth defects such as a kidney or abdominal wall defect.
	www.fha.state.md.us /genetics/html/afp_tst.html (2046 words)

	Triple Screen Test : American Pregnancy Association
		The triple screen test is performed between the 15th and 20th week of pregnancy although results obtained in the 16th -18th week are said to be the most accurate.
		It is important to remember that the triple test is a screening test and not a diagnostic test.
		The triple screen is a routine screening that is not an invasive procedure and poses no risks to the mother or baby.
	www.americanpregnancy.org /prenataltesting/tripletest.html (888 words)

	DOWNS SYNDROME: PRENATAL SCREENING AND DIAGNOSIS PEDIATRIC ONCALL (Site not responding. Last check: 2007-11-03)
		The triple test fails to detect 10 to 15 percent of trisomy 21 pregnancies in older age group.
		First-trimester screening by means of maternal age and measurement of nuchal translucency could provide a trisomy 21 detection rate of 63 percent, with a 5 percent false-positive rate.
		This is important because the large majority of positive screening tests occur in normal pregnancies Adverse psychological effects of screening tests include the fear of discovering an abnormal pregnancy as well as anxiety over possible complications from diagnostic and therapeutic procedures.
	www.pediatriconcall.com /fordoctor/DiseasesandCondition/downsyndrome_pre.asp (1086 words)

	Should I have the maternal serum triple or quadruple test (triple or quad screen)?
		The maternal serum triple screen, sometimes called the triple test or MSAFP+ test, measures the amounts of three substances in a pregnant woman's blood: alpha-fetoprotein (AFP), human chorionic gonadotropin (hCG), and estriol (uE3).
		The relatively new quadruple screen combines the triple screen and a test for the protein inhibin-A, which is produced by the fetus and the placenta.
		Based on this study, the quadruple test is more likely to pick up Down syndrome and may be less likely to be false-positive than the triple screen.
	www.meritcare.com /hwdb/showtopic.aspx?module_abbrev=HWDP&pd_hwid=aa21828&topic_name=Should (1584 words)

	Medical References: Maternal Blood Screening for Down Syndrome and Neural Tube Defects (Site not responding. Last check: 2007-11-03)
		If the maternal serum screening test shows that a woman is at increased risk of having a baby with an NTD, her provider may recommend a detailed ultrasound examination (sometimes referred to as a targeted, comprehensive or level II exam), amniocentesis or both.
		The maternal serum screening test leads to the prenatal diagnosis of about 95 percent of cases of anencephaly, 85 percent of cases of serious spina bifida, as well as 65 percent of cases of Down syndrome (about 75 percent of Down syndrome cases if the quadruple screen is used).
		Several studies recently reported that a screening test done between 10 and 14 weeks of pregnancy may be as accurate as the maternal serum screening test done in the second trimester.
	www.marchofdimes.com /professionals/681_1166.asp (2338 words)

	Down Syndrome - Quest Diagnostics Patient Health Library (Site not responding. Last check: 2007-11-03)
		The quadruple test can detect most Down syndrome cases, and it may be less likely than the triple screen to deliver false-positive results.
		For example, when a mother is most concerned with screening accuracy and does not want to have amniocentesis, her doctor may recommend a combination of fetal ultrasound and blood test during the first trimester plus a triple or quad screen during the second trimester.
		However, the tests usually are offered to pregnant women who are 35 or older because of their increased risk for having a fetus with abnormal chromosomes.
	www.questdiagnostics.com /kbase/topic/major/hw167776/examtest.htm (1290 words)

	Quad Screen : American Pregnancy Association
		The quad screen is a maternal blood screening test that is similar to the Triple Screen Test (also know as AFP Plus and the Multiple Marker Screening).
		The quad screen test is performed between the 16th and 18th week of pregnancy.
		It is important to remember that the quad screen is a screening test and not a diagnostic test.
	www.americanpregnancy.org /prenataltesting/quadscreen.html (841 words)

	LargeWomen and Prenatal Testing
		But she has found through extensive interviewing of parents involved in such testing that most of them were simply unprepared to confront the scope of the types of decisions presented by prenatal testing, and that choosing such testing often changed the way a woman experienced pregnancy in subtle ways.
		AFP tests (alpha-fetoprotein tests) and the newer triple screen (or multiple marker) tests are used to screen for possible birth defects in fetuses.
		The strength of the screening test is that it identifies some cases of a problem that might go undiscovered with no testing, and is much less time-consuming and costly than universal testing because it narrows the field of who should be further tested.
	www.plus-size-pregnancy.org /largewom.htm (12789 words)

	Smart Moms \| Prenatal Tests
		A screening test is a test that is performed when there are no symptoms or known risk factors present.
		If your screening test shows a higher-than-average risk for having a baby with a certain defect, further tests may be used for diagnosis.
		Maternal serum screening tests, such as the alpha-fetoprotein test and the multiple marker screening test, assess your risk of having a baby with a birth defect.
	www.med.umich.edu /obgyn/smartmoms/tests/serum.htm (825 words)

	Triple screen question (Site not responding. Last check: 2007-11-03)
		Whenever the gestational dates change significantly, usually as a result of an ultrasound study, the triple screen results should be recalculated.
		In this question, the ultrasound changes the gestational age from 15 to 19 weeks (15+4) at the time the triple screen was drawn.
		The triple screen should be recalculated for 19 weeks gestation.
	www.hal-pc.org /~johnv/Pans4.htm (122 words)

	Triple screen question (Site not responding. Last check: 2007-11-03)
		The triple screen should be recalculated – inform Denton Lab of the new EDC.
		The triple screen needs to be recalculated only if the triple screen was originally positive.
		Draw a new triple screen sample today, unless the gestational age is 22 weeks or greater.
	www.hal-pc.org /~johnv/Pques4.htm (80 words)

	Maternal serum triple or quadruple screen
		False-positive test results are increasingly likely as you approach age 40 and can cause undue stress and lead to unnecessary invasive testing (such as amniocentesis).
		If your test results are abnormal, your health professional may use a fetal ultrasound to make sure the fetal age, and therefore your screen results, are as accurate as possible.
		If your serum screen estimates that your risk of carrying a fetus with Down syndrome is higher than the average risk for your age, you may choose to have amniocentesis.
	www.webmd.com /hw/health_guide_atoz/ta7038.asp (684 words)

	9NEWS.com - Colorado's On-Line News Leader (Site not responding. Last check: 2007-11-03)
		One of the tests women take between the 15th and 18th week of pregnancy is called a Triple Screen.
		The test combines a woman's age with a measurement of 3-4 hormones in her blood.
		An amniocentesis is the only diagnostic test available to determine once and for all whether or not the baby will be born with the abnormality.
	www.9news.com /health/triscreen.html (353 words)

	Triple Screen blood test/Maternal Serum
		I'm nervous about having this done, because the test results are not 'conclusive' (you could have abnormal results and still have a normal baby) but they could lead you to having more testing (high resolution ultra sound, amnio,etc.) so you could 'confirm' that there should be concerns.
		There are far too many false positives with those tests and usually by the time the results come in, you have had your 20 week anatomy scan which would have most likely picked up any abnormalities.
		My best friend went ahead with the test and before the results came in, she had the u/s which showed a perfectly normal and healthy little boy, yet her tests came back with an elevated risk.
	www.medhelp.org /PERL6/MATERNAL/messages/37357.html (765 words)

	IVFer's Prenatal Testing Page
		Triple Screen is a blood test that measures three chemicals: MS-AFP, Estriol, and HCG.
		The median levels of the triple markers were 0.95 multiples of the median (MoM) for alpha-fetoprotein (AFP), 0.90 MoM for unconjugated estriol (E3), and 1.22 MoM for hCG.
		Like the Triple Screen, this means your risk for problems has gone way down and you probably don't want to risk an amnio.
	www.ivfer.com /tests.htm (2100 words)

	MotheringDotCommune Forums - Triple Screen/AFP test? Quad Screen results
		With my dd I was torn whether to have the test or not since I know it is not a very reliable test and really only predicts Down's 60% of the time correctly.
		I knew that if I had the test done they would let me have a level II ultrasound which is more indicative of down's so even though the ATP isn't a reliable test - having the test would enable me to get the level II ultrasound.
		I found a lot of comfort from many women who noted, as have others here, that the blood tests are often misleading and that screening tests are not diagnostic tests.
	www.mothering.com /discussions/printthread.php?t=382945 (963 words)

	Elevated risk on triple screen test
		I am nearly 17 wks pregnant and just received my triple screen results on Friday; my test came back with an elevated risk for trisomy 18; the number they gave me was 1 in 95.
		This is my first pregnancy, so I have no comparison base, but I know several women (more than not) who had an "elevated risk" after the triple screen or quod, and all of their babies are healthy.
		Indeed, when I first told one of my friends I was pregnant she told me not to take the test because she went through the agony of an elevated risk too and has a healthy baby boy.
	www.medhelp.org /perl6/Maternal/messages/37658.html (792 words)

	Prenatal Alpha-Fetoprotein Test (Site not responding. Last check: 2007-11-03)
		The AFP test is a part of what is called the triple test, which looks at three substances normally present in the bloodstream of pregnant women: AFP, and two pregnancy hormones called estriol and human chorionic gonadotropin (HCG).
		The AFP and the triple screen are usually done between 16 and 18 weeks after the last menstrual period.
		In this test, the doctor inserts a thin needle through the abdominal wall and into the uterus to withdraw a few teaspoons of amniotic fluid, which can be studied to see if the fetus's chromosomes are normal.
	www.healthatoz.com /healthatoz/Atoz/dc/tp/tpafp.jsp (803 words)

	Multiple marker screening (AFP)
		The multiple marker test (sometimes referred to as the triple screen) can tell you whether your baby is at an increased risk of having certain birth defects and genetic abnormalities.
		Current research indicates that this test will detect 75 to 85 percent of neural tube defects (such as spina bifida and anencephaly) and 60 percent of Down syndrome in babies of women younger than 35, and 75 percent of neural tube defects and Down syndrome in babies of women 35 and older.
		For years, women were screened for AFP alone in a test called the maternal serum AFP or MSAFP, but now most labs check for all three substances because they can tell more that way.
	www.babycenter.com /refcap/pregnancy/prenatalhealth/1487.html (2173 words)

	Triple Screening in Pregnancy: What It Is and What to Expect -- familydoctor.org (Site not responding. Last check: 2007-11-03)
		A triple screen is a blood test that measures three things called alpha-fetoprotein, human chorionic gonadotropin and unconjugated estriol.
		The results of the blood test can help your doctor see if your baby may be at higher risk for certain birth defects such as Down syndrome and neural tube defects.
		Triple screens are most accurate when done between the 16th and the 18th weeks of your pregnancy.
	familydoctor.org /761.xml (370 words)

	"Quad" test
		So if you won't test because you wouldn't abort, then consider testing as a tool to be sure that you are doing everything possible to keep baby safe and provide a full term healthy gestation and birth.
		Maternal blood screening tests are a way to check the risk of birth defects before a baby is born.
		The tests measure the levels of 3 or 4 substances in a sample of the mother's blood during pregnancy.
	www.babyfit.com /archive_posts.asp?imboard=64&imParent=1224713 (919 words)

	Preeclampsia Foundation Forums - Positive Triple Screen? (Site not responding. Last check: 2007-11-03)
		I subsequently chose to have the test when pregnant with Chloe, I'd read here about the anecdotal evidence regarding "increased risk" results possibly implying a higher risk of preeclampsia.
		I had a negative test but a slightly elevated hCG result : 2.52 and I guess normal is less than 2.0.
		I think it is interesting that many woman with pg related issues other than birth defects have pos results from the triple marker test w/o the baby having any birth defects.
	www.preeclampsia.org /forum/topic.asp?TOPIC_ID=2602 (897 words)

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