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Topic: Triprolidine

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Brompheniramine

Promethazine

Antihistamine

Diphenhydramine

Dimenhydrinate

Chlorphenamine

Ivermectin

Permethrin

	MedlinePlus Drug Information: Pseudoephedrine and Triprolidine
		The combination of pseudoephedrine (a decongestant) and triprolidine (an antihistamine) relieves itchy, watery eyes; sneezing; and runny or stuffy nose caused by hay fever, allergies, and the common cold.
		The combination of pseudoephedrine and triprolidine comes in capsules, tablets, extended-release (long-acting) capsules, and liquid to take by mouth.
		Pseudoephedrine and triprolidine may cause an upset stomach.
	www.nlm.nih.gov /medlineplus/druginfo/medmaster/a601103.html (0 words)

	triprolidine and pseudoephedrine - Drug Finder - MSN Health & Fitness (Site not responding. Last check: 2007-10-10)
		Triprolidine and pseudoephedrine is used to treat nasal congestion and sinusitis (inflammation of the sinuses) associated with allergies, hay fever, and the common cold.
		Triprolidine and pseudoephedrine is in the FDA pregnancy category B. This means that it is not expected to be harmful to an unborn baby.
		Triprolidine and pseudoephedrine is available in many brand and generic formulations both with a prescription and over the counter.
	health.msn.com /drugfinder/articlepage.aspx?cp-documentid=100106852 (1343 words)

	Title: Stability of Triprolidine Hydrochloride in liquid dosage form
		Triprolidine HCl is a propylamine antihistamine commonly used as an over the counter drug found in liquid and solid dosage form preparations.
		The pH-rate profile for the degradation of Triprolidine HCl was found to exhibit a bell shape with base catalysis portion above pH 7.0 but this portion was not found in the presence of 60% Sucrose which lowered the degradation rate at pH above 8.0, but increased it at pH 5, 6, and 7 aggressively.
		Also Triprolidine HCl UV scan was found to shift under different pH conditions but the isosbestic point at the wavelength 270nm was found to have constant absorbance at different pH conditions, thus it was chosen to be the wavelength used to detect the elution of Triprolidine HCl from the HPLC system.
	www.environment.gov.jo /triprolidine_stability.htm (408 words)

	Triprolidine and Pseudoephedrine
		Triprolidine is a member of the propylamine (alkylamine) chemical class of H1-antagonist antihistamines.
		Triprolidine has a shorter half-life and duration of action than most of the other alkylamine antihistamines.
		Like all H1-antagonist antihistamines, the mechanism of action of triprolidine is believed to involve competitive blockade of H1-receptor sites resulting in the inability of histamine to combine with its receptor sites and exert its usual effects on target cells.
	www.metagenics.com /ADAM/41/129100.html (603 words)

	Sudafed Plus
		Triprolidine is more likely to cause drowsiness than the newer group of non-sedating anti-histamines.
		When triprolidine is taken with a mono-amine oxidase inhibitor (MAOI) antidepressant or a tricyclic anti-depressant there is an increase in sedation and side-effects such as dry mouth, blurred vision and urinary retention.
		The sedating effect of triprolidine may be increased when taken at the same time as other medicines that depress the central nervous system such as alcohol or sleep aiding preparations.
	www.netdoctor.co.uk /medicines/100002482.html (662 words)

	Sudafed Plus Tablets , SPC from the eMC
		Although pseudoephedrine and triprolidine have been in widespread use for many years without apparent ill consequence, there are no specific data on their use during pregnancy.
		Pseudoephedrine and triprolidine are excreted in breast milk in small amounts but the effect of this on breast fed infants is not known.
		In common with other antihistamines, triprolidine hydrochloride is rapidly absorbed, peak plasma levels being observed 2 hours after an oral dose, metabolised in the liver and excreted, mainly as metabolites in the urine.
	emc.medicines.org.uk /emc/assets/c/html/DisplayDoc.asp?DocumentID=7108 (1088 words)

	Absorption Systems: P-glycoprotein limits the brain penetration of nonsedating but not sedating H1-antagonists.
		The bidirectional apparent permeability was determined by measuring the amount of compound at the receiving side at 5 h.
		In contrast, the brain-to-plasma AUC ratio between KO and WT was comparable for hydroxyzine, diphenhydramine, and triprolidine.
		Likewise, the efflux ratio between basolateral to apical and apical to basolateral was 4.6- and 6.6-fold higher in MDR1-MDCK than the parental MDCK for certirizine and desloratadine, respectively, whereas it was approximately 1 for diphenhydramine and triprolidine.
	www.absorption.com /Site/References/Default.aspx?ID=16 (280 words)

	ACUFLU P Syrup
		The most common side-effects of triprolidine hydrochloride are sedation varying from slight drowsiness to deep sleep, and including inability to concentrate, lassitude, dizziness, hypotension, muscular weakness and inco-ordination.
		Triprolidine HCL may mask the warning symptoms of damage caused by ototoxic drugs and may affect the metabolism of drugs in the liver.
		The depressant effects of triprolidine are aggravated by alcohol, anaesthetics, hypnotics, sedatives, tricyclic antidepressants and phenothiazine.
	home.intekom.com /pharm/apotex/acuflups.html (1123 words)

	MEDIFED LINCTUS SOLUTION
		Triprolidine can cause sedation varying from slight drowsiness to deep sleep, and including inability to concentrate, lassitude, dizziness, hypotension, muscular weakness, and inco-ordination.
		Triprolidine may enhance the sedative effect of central nervous system depressants including alcohol, barbiturates, hypnotics, narcotic analgesics, sedatives, and tranquillisers.
		Triprolidine intoxication may lead to ataxia, death from respiratory failure, and respiratory collapse.
	home.intekom.com /pharm/cipla/medifedl.html (850 words)

	Multi-Action Actifed Chesty Coughs , SPC from the eMC
		Triprolidine provides symptomatic relief in conditions believed to depend wholly, or partly, upon the triggered release of histamine.
		After oral administration of a single dose of 2.5 mg triprolidine to adults, the onset of action, as determined by the ability to antagonise histamine-induced wheals and flares in the skin, was within 1 to 2 hours.
		The apparent volume of distribution of triprolidine was approximately 6.5 l/kg for the tablet formulation and 7.5 l/kg for the syrup.
	emc.medicines.org.uk /emc/assets/c/html/displaydoc.asp?documentid=7093 (1821 words)

	RxMed: Prescribing Information (Site not responding. Last check: 2007-10-10)
		Fixed drug eruption due to pseudoephedrine and lichenoid skin eruption due to triprolidine have been reported but both these reactions should be regarded as rare events.
		Treatment: There is no specific antidote for triprolidine or pseudoephedrine.
		General measures to eliminate the drug and reduce its absorption should be undertaken.
	www.rxmed.com /b.main/b3.herb.monos/b3.1.monographs/actifed.html (603 words)

	Actifed dry coughs
		By decreasing blood flow, fluid congestion in the nose and sinuses is reduced.
		Triprolidine is a sedating antihistamine which acts on histamine H1 receptors.
		The combination of triprolidine with pseudoephedrine and dextromethorphan is used to relieve the symptoms of colds and flu, such as nasal congestion, cough and runny nose, where these are associated with a dry cough.
	www.netdoctor.co.uk /medicines/100000020.html (871 words)

	acetaminophen/triprolidine/pseudoephedrine - [Medication]
		It blocks the effects of the naturally occurring chemical histamine in the body.
		Triprolidine prevents sneezing; itchy, watery eyes and nose; and other symptoms of allergies and hay fever.
		Other medications may also contain triprolidine, pseudoephedrine, acetaminophen, or other similar drugs, and you may accidentally take too much of these medicines.
	www.peacehealth.org /kbase/multum/d03330a1.htm (1444 words)

	Riyadh Pharma Syrup Line (Site not responding. Last check: 2007-10-10)
		FLU-CARE provides the combined effect of Triprolidine Hydrochloride and Pseudoephidrine Hydrochloride for a symptomatic relief of rhinorrhea, sneezing and other nasal allergic conditions.
		Triprolidine Hydrochloride is a propylamine-derivative antihistamine and is used in the management of nasal allergies.
		Pseuodoephidrine Hydrochloride is a sympathomimetic drug, which acts directly on both alpha and beta adrenergic receptors.
	www.riyadhpharma.com /syrups.htm (1062 words)

	Maternal & Infant Briefs Jan/Feb01
		Studies on pseudoephedrine, triprolidine, and loratidine in humans show that a very low percentage of the oral dose actually reaches the infant through the breast milk.
		The AAP considers pseudoephedrine and triprolidine to be compatible with breastfeeding and therefore, these should be the first-line choices for relief of cold symptoms.
		Codeine is also considered compatible with breastfeeding by the AAP and may be used for short-term relief as a cough suppressant.
	nutrition.ucdavis.edu /briefs/Issues/JanFeb01.htm (2001 words)

	Always, there have been those who were more cautious than others and those who were more bold than others. (Site not responding. Last check: 2007-10-10)
		These clandestine methamphetamine labs pose many triprolidine and pseudoephedrine dangers to society, for example during the calendar year 2002 they caused 194 fires, 117 explosions, and 22 deaths.
		A written report must be submitted to the DEA within 15 days of triprolidine and pseudoephedrine discovery of the theft or loss.
		Morgan triprolidine and pseudoephedrine said the Drug Task Force will mail a letter to every store in the county where cold and allergy medicines are sold to inform them of the law and what is expected to ensure compliance.
	hypeimplant.sitesled.com /monofilament-bookfish.html (764 words)

	P-Glycoprotein Limits the Brain Penetration of Nonsedating but not Sedating H1-Antagonists -- Chen et al. 31 (3): 312 ...
		Hydroxyzine, triprolidine, and diphenhydramine were obtained from Sigma-Aldrich (St. Louis, MO).
		Transepithelial Transport of the Two Sedating H1-Antagonists Triprolidine and Diphenhydramine and the Two Nonsedating H1-Antagonists Cetirizine and Desloratadine in MDR1-MDCK and parental MDCK Cells.
		ratio for triprolidine and diphenhydramine was approximately 1
	dmd.aspetjournals.org /cgi/content/full/31/3/312 (3985 words)

	Buy Actifed Cold and Allergy (Triprolidine/Pseudoephedrine Tablets) at Online Canada Pharmacy
		Actifed Cold and Allergy is comes in the class of drugs Pseudoephedrine hydrochloride, Triprolidine hydrochloride.
		Actifed Cold and Allergy works by preventing the effects of a substance called histamine, which is produced by the body.
		Histamine is a chemical that is released in response to allergic or inflammatory stimuli.
	www.abconlinepharmacy.com /ns/customer/product1438-c-p1 (1292 words)

	Healthopedia.com Drugs Information - Cough/Cold Combinations
		They work by preventing the effects of a substance called histamine, which is produced by the body.
		Triprolidine, Pseudoephedrine, and Codeine (trye-PROE-li-deen, soo-doe-e-FED-rin, and KOE-deen)
		Triprolidine, Pseudoephedrine, Codeine, and Guaifenesin (trye-PROE-li-deen, soo-doe-e-FED-rin, KOE-deen, and gwye-FEN-e-sin)*
	www.healthopedia.com /drugs/detailed/cough-cold-combinations (1786 words)

	Relevant Medicical Information 4 UK - HISTAFED--(PSEUDOEPHEDRINE-HYDROCHLORIDE;-TRIPROLIDINE-HYDROCHLORIDE)
		We hope this website provide relevant and important piece of information for general public as well as medical professionals in UK and other countries.
		Histafed Chemical: Pseudoephedrine Hydrochloride, Triprolidine Hydrochloride: Generic: N/A : 20 tabs $25.20 : Medicine: Histantil Chemical: Promethazine, Promethazine (Promethazine Hydrochloride), Promethazine...
		Relevant Medicical Information 4 UK - Category Name start from HA-HX...
	www.4uk.net /dir/drugs/HA-HX/HISTAFED--(PSEUDOEPHEDRINE-HYDROCHLORIDE;-TRIPROLIDINE-HYDROCHLORIDE)/HISTAFED--(PSEUDOEPHEDRINE-HYDROCHLORIDE;-TRIPROLIDINE-HYDROCHLORIDE).htm (0 words)

	Effect of Inflammatory Mediators on the Electrophysiology of the Human Oviduct -- Downing et al. 61 (3): 657 -- Biology ...
		Change in transepithelial potential difference with increasing histamine concentration applied to the basal surface of the cells in control (n = 12) cultured human tubal epithelial cells and cells treated with 1 µM triprolidine (n = 6), 10 µM ranitidine (n = 6), or 1 µM thioperamide (n = 6).
		Change in transepithelial potential difference with increasing histamine concentration applied to the apical surface of the cells in control (n = 12) cultured human tubal epithelial cells and cells treated with 1 µM triprolidine (n = 6), 10 µM ranitidine (n = 6), or 1 µM thioperamide (n = 6).
		Frequency of contraction of circular muscle of human oviduct with increasing histamine concentration in a) control tissue (n = 10) or tissue preincubated with 1 µM triprolidine (n = 5) or 1 µM thioperamide (n = 5) and b) control tissue (n = 10) or tissue preincubated with 10 µM ranitidine (n = 6).
	www.biolreprod.org /cgi/content/full/61/3/657 (4897 words)

	Antihistamines, Decongestants, and Analgesics (Systemic) - MayoClinic.com (Site not responding. Last check: 2007-10-10)
		They work by preventing the effects of a substance called histamine, which is produced by the body.
		brompheniramine, chlorpheniramine, dexbrompheniramine, diphenhydramine, pheniramine, phenyltoloxamine, pyrilamine, and triprolidine.
		Triprolidine, Pseudoephedrine, and Acetaminophen (trye-PROE-li-deen soo-doe-e-FED-rin and a-set-a-MIN-oh-fen)
	www.mayoclinic.com /health/drug-information/DR202062 (3346 words)

	Buy Sulidine Prophedin (Pseudoephedrine and Triprolidine) Online Without Prescription Needed at 1meds (Site not responding. Last check: 2007-10-10)
		No hidden fee on Actifed tab, Sulidine Prophedin - Pseudoephedrine and Triprolidine.
		Generic name: Triprolidine & Pseudoephedrine, Manufacturer: SM pharma, Size: 100 tabs
		Although side effects from pseudoephedrine and triprolidine are not common, they can occur.
	www.1meds.com /Actifed_tab.html (640 words)

	Triprolidine and Pseudoephedrine
		If you have an allergy to pseudoephedrine, triprolidine, or any other part of the medicine.
		Triprolidine, if taken before coming in contact with the material that causes the allergy, blocks the allergic reaction by minimizing/preventing the body's reaction to the allergen.
		Pseudoephedrine shrinks swollen nasal tissue and opens up passages.
	www.umm.edu /altmed/ConsDrugs/TriprolidineandPseudoephedrinecd.html (585 words)

	Actifed
		Symptoms of a Actifed overdose include a dry mouth, large pupils, flushing, nausea, and vomiting.
		Dangerous sedation, dizziness, or drowsiness may occur if Actifed is taken with any of these medications.
		Do not take Actifed if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days.
	www.drugs.com /actifed.html (1299 words)

	Medbroadcast Drug Info
		If it is almost time for your next dose, skip the missed dose and carry on with your regular schedule.
		Each white-to-off-white tablet, code number "WELLCOME P4B" on same side as score mark, contains triprolidine 4 mg, pseudoephedrine 60 mg, and codeine 20 mg.
		anyone allergic to codeine or other narcotics, triprolidine, other antihistamines of similar chemical structure, pseudoephedrine,or any of the ingredients of the medication
	www.medbroadcast.com /drug_info_details_pf.asp?brand_name_id=720 (856 words)

	eMedicine - Toxicity, Antihistamine : Article by David J McCann, MD (Site not responding. Last check: 2007-10-10)
		Synonyms and related keywords: alkylamine, brompheniramine, triprolidine, ethanolamine, clemastine, diphenhydramine, doxylamine, ethylenediamine, tripelennamine, phenothiazine, promethazine, piperidine, fexofenadine, loratadine, piperazine, cetirizine, meclizine, antihistamine toxicity, H1-receptor antagonists, nonsedating H1 blockers, antihistamine poisoning, antihistamine exposure
		Blockade of central H2 receptors alters CNS neurotransmission and may cause delirium, confusion, agitation, and seizures (rare).
		Alkylamine derivatives (eg, chlorpheniramine, brompheniramine, triprolidine) are among the most potent antihistamines.
	www.emedicine.com /emerg/topic38.htm (5301 words)

	Cough/Cold Combinations (Systemic) - MayoClinic.com (Site not responding. Last check: 2007-10-10)
		Some examples of antihistamines contained in these combinations are: bromodiphenhydramine (broe-moe-dye-fen-HYE-dra-meen), brompheniramine (brome-fen-EER-a-meen), carbinoxamine (kar-bi-NOX-a-meen), chlorpheniramine (klor-fen-EER-a-meen), dexchlorpheniramine (dex-klor-fen-EER-a-meen), diphenhydramine (dye-fen-HYE-dra-meen), doxylamine (dox-ILL-a-meen), phenindamine (fen-IN-da-meen), pheniramine (fen-EER-a-meen), phenyltoloxamine (fen-ill-tole-OX-a-meen), pyrilamine (peer-ILL-a-meen), promethazine (proe-METH-a-zeen), and triprolidine (trye-PROE-li-deen).
		Triprolidine, Pseudoephedrine, and Codeine (trye-PROE-li-deen, soo-doe-e-FED-rin, and KOE-deen)
		Triprolidine, Pseudoephedrine, Codeine, and Guaifenesin (trye-PROE-li-deen, soo-doe-e-FED-rin, KOE-deen, and gwye-FEN-e-sin)
	www.mayoclinic.com /health/drug-information/DR202165 (5098 words)

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