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Topic: Tumour

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pituitary tumours

tumour marker

Malignant Tumour

solid tumour

Tumour Necrosis Factor

Tumour Diary

metastatic tumour

suppresses tumours

Tumour cells

Lectures on Tumours

Benign tumours

In the News (Mon 13 Oct 08)

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	Brain Tumour UK - home
		Andrew Patterson is a determined man and that determination has enabled him to raise more than £10,000 and persuaded the Basingstoke branch of Shoosmiths, a law firm and his employer, to make Brain Tumour UK their charity of the year.
		Brain Tumour UK supports brain tumour patients, their families, friends and carers through making connections, providing information and funding research.
		The mother of a three-year-old boy who died from a brain tumour has praised the signing of a major agreement by universities to work together on ground-breaking research into the disease.
	www.braintumouruk.org.uk (939 words)

	The Wilms' Tumour Resource Directory
		Wilms' tumour is a cancer of the kidney which is very different to adult kidney cancer.
		Most patients are under 5 years of age at diagnosis, though Wilms' tumour is sometimes seen in older children and occasionally in young adults.
		Trevor's Story Trevor was diagnosed with Wilms' tumour at age 4.
	www.cancerindex.org /ccw/guide2w.htm (829 words)

	Tumour - LoveToKnow 1911
		For instance, a small tumour may cause intense pain by pressing on a nerve, or dropsical swelling of a limb by obstructing a vein, or death from suffocation by blocking the larynx.
		There are some tumours whose histological appearances seem to be on the borderline between the two conditions, and often these are the very cases in which the clinical features give no direct clue to their nature.
		Ribbert has suggested that tumour formation may be due to "alteration of tissue tension." In his opinion the various cells of the body are normally held in a state of equilibrium by some condition of mutual interdependence amongst themselves.
	www.1911encyclopedia.org /Tumour (5832 words)

	PRH - Tumour Types D-M
		In this situation, the tumour is identified as an anaplastic (malignant) oligo-astrocytoma.
		Radiation is very effective against this tumour and is generally done to the entire head and spinal cord because of the high possibility of seeding malignant cells by way of the cerebrospinal fluid.
		Tumours that spread to the brain may be single (solitary metastasis) or multiple.
	www.braintumour.ca /braintumour.nsf/eng/PRH-TumourTypesD-M (1984 words)

	Tumours
		Headaches, blurred vision, nausea and vomiting may all be brought on by a tumour of the brain (as well, of course, as by far less serious conditions).
		A tumour of the meninges (a meningioma) is typically slow-growing but may prove fatal because the pressure it exerts on the brain.
		After removing the tumour, the bone flap is replaced and held tightly against the rest of the skull by wire structures.
	library.thinkquest.org /27807/Cli/BrCliTumours.html (857 words)

	Tumour Microcirculation
		Blood flow to the tumour was unaffected by ET-1 treatment, whereas blood flow to the normal tissues was reduced, with the exception of the heart and the brain in which blood flow was increased.
		SX6c however did not modify tumour vascular resistance, contrasting with an increase in vascular resistance in all the normal tissues examined, which suggests that the HSN rat tumour lacks a population of functional ETB receptors on the vasculature capable of modifying vascular tone as observed in the normal tissues.
		The developing tumour vasculature has structural and functional differences from that in normal tissues, however, little is known about the changes that are induced in endothelial cells by the tumour microenvironment and whether they are therapeutically exploitable.
	www.graylab.ac.uk /lab/report95/group5.html (3127 words)

	The Fibromatosis /Desmoid Tumour Site
		Tumours growing on vital structures such as major blood vessels, organs, major nerves or the brain will be more difficult to treat without risking damage to surrounding tissues.
		Desmoid tumours are very individual in their responses to treatment, and no one treatment alone seems to have a high success rate.
		Desmoid tumours in the head and neck recur, on average, in 70% of cases.
	whippetrun_bc.tripod.com /the_fibromatosis_page (1044 words)

	Brain Tumour (Site not responding. Last check: )
		Brain tumours are responsible for approximately 2% of all cancer deaths.
		Most tumours are surrounded by a zone of oedema which contributes to the overall mass effect of the tumour.
		Patients who have tumours affecting vital centres in the dominant hemisphere with hemiparesis and/or dysphasia or aphasia, and patients who are elderly and functionally poor are not suitable for major surgery and may at best have the diagnosis confirmed by biopsy with the option to give radiotherapy.
	medweb.bham.ac.uk /neurosurgery/Braintumour.html (1277 words)

	tumour (Site not responding. Last check: )
		After the surgery specimens of the tumour are analysed to ascertain the nature of the cancerous cells.
		Tumour cells are usually sensitive to radiotherapy treatment, whereas normal cells are relatively insensitive.
		It is unclear whether the tumour has re-grown or whether the swelling is a reaction to the radiotherapy treatment.
	www.jamesdorrington.homestead.com /tumour.html (3858 words)

	Solid Tumour Growth
		Angiogenesis is the process by which tumours induce blood vessels from the host tissue to sprout capillary tips which migrate towards and ultimately penetrate the tumour, providing it with a circulating blood supply and, therefore, an almost limitless source of nutrients.
		We assume that the tumour adopts a multi-layered strucutre, with proliferating cells in the outer shell, quiescent cells occupying the adjacent, middle shell, and necrotic cells confined to the central core.
		Thus quiescence is a reversible state of a tumour cell.) Further growth of the tumour is accompanied by an increase in the quiescent cell population and a further reduction in the minimum nutrient concentration until eventually tumour cells towards the centre of the tumour, being starved of vital nutrients, become necrotic.
	www.maths.dundee.ac.uk /~chaplain/tumourgrowth.html (908 words)

	Brain Tumour Analysis Project Home
		The conventional method of treating gliomas with conformal radiotherapy is to irradiate both the visible tumour mass observed on the MRI scan as well as a 2cm margin which typically includes both healthy tissue and malignant tendrils.
		Tumour segmentation: recognizing the tumour mass and its boundaries on the MRI scan either manually (drawing the contour of the tumour on the image) or automatically.
		Diffusion modeling: simulating the tumour growth, given an initial tumour volume of a patient at one time, based on the labels predicted through classification, produces the predicted shape of the tumour in 3D at a later time when the tumour has reached a particular volume.
	www.cs.ualberta.ca /~btgp/gliomaModeling.php (1023 words)

	Follicular Dendritic Cell Tumour
		Tumours of the follicular dendritic cells are rare tumours.
		Immuno-phenotyping of this tumour confirmed the diagnosis of a follicular dendritic cell tumour.
		This kind of tumour is especially prevalent in the mucosa of the pharynx, larynx and esophagus.
	www.ispub.com /ostia/index.php?xmlFilePath=journals/ijpa/vol3n1/fdc.xml (1310 words)

	Carcinoid tumours : Cancerbackup
		If the tumour is contained in one area (localised), or if there has been only limited spread (regional), surgery is usually the first choice of treatment.
		If the tumour has spread to other parts of the body (metastatic) but there are only one or two areas – for example, in the liver – surgery may still be possible because of the slow growth of the tumour.
		It may sometimes be used to treat carcinoid tumours that have spread, with the intention of reducing the tumour and the secretion of serotonin, and of prolonging a good quality of life.
	www.cancerbackup.org.uk /Cancertype/Neuroendocrine/Carcinoidtumours (1705 words)

	AboutKidsHealth: Brain Tumours: Other Tumour Types (Site not responding. Last check: )
		These tumours grow in the upper part of the brain, in the cerebrum and are cancerous (malignant).
		This is a rare, benign tumour in the pituitary gland, which is located in the centre of the brain.
		This is a benign, slow-growing tumour in the peripheral nerves.
	www.aboutkidshealth.ca /clinicalAreas.asp?pageContent=BT-nh1-03g (774 words)

	Tumour Lysis Syndrome
		Clinically, tumour lysis syndrome occurs in about 6% of patients being treated for non-hodgkin's lymphoma, but laboratory parameters consistent with it are seen in up to 42% of patients.
		Tumour lysis syndrome causes a triad of hyperkalaemia, hyperphosphataemia and hyperuricaemia and leads to acute renal failure.
		Tumour lysis syndrome is often predictable, and close monitoring of at-risk patients usually allows for effective treatment or even prevention.
	www.virtualbloodcentre.com /diseases.asp?did=737 (1099 words)

	brain-tumour.net (medullablastoma)
		This tumour can infiltrate other parts of the brain, as well as (occasionally) reaching other parts of the body.
		Treatment consists of surgical removal of as much as the tumour as possible, followed by different treatment.
		You may have noticed a common pattern in the method of treating childhood brain tumours - children under the age of 3 are rarely giving radiation therapy, because it is thought that this could be harmful to a child (and brain) of such a young age, developing so quickly.
	www.brain-tumour.net /tumours/medul.htm (147 words)

	Wilms' tumour in children : Cancerbackup (Site not responding. Last check: )
		Very rarely, people who have Wilms' tumour also have other particular conditions present at birth (congenital malformations), such as lack of an iris in the eye (aniridia), abnormalities of the genitals, and a condition where one side of the body is slightly larger than the other (hemihypertrophy).
		Occasionally, the tumour may bleed slightly and this can cause irritation in the area of the kidney, which may be painful.
		Depending on the stage of the tumour at diagnosis, radiotherapy may also be given to the area of the affected kidney or to the whole abdomen.
	www.cancerbackup.org.uk /Cancertype/Childrenscancers/Typesofchildrenscancers/Wilmstumour (1482 words)

	Brain Tumour Analysis Project Home
		Our experiments confirm that it is easiest to segment the enhancing tumour area; this is expected as this area is the most visible on the MRIs.
		The 'tumour + edema' region is more challenging, as it is not always as easy to see in the MR images.
		The most challenging is gross tumour volume, which is often very difficult to see visually -- indeed, many times the only way for a physician to determine gross tumour volume is by means of biopsy.
	www.cs.ualberta.ca /~btgp/results.php (845 words)

	Baby beats footy-size tumour - National - smh.com.au
		The tumour on the base of his spine was the size of a small football when he arrived 10 weeks early.
		John Smyth, a newborn care specialist at the hospital, said such a tumour in utero was rare.
		While there was a risk the non-cancerous tumour - which grew from the base of Bailey's spine and extended around his bottom - could return, Dr Smyth said he hoped Bailey would "have a normal life".
	www.smh.com.au /news/national/baby-beats-footysize-tumour/2006/08/19/1155408071231.html (536 words)

	Wilms Tumour
		The prognosis for children with Wilms tumour depends largely on the stage, or extent, of the disease at the time of diagnosis and on certain microscopic features of the cancer cells, assessed after surgery to remove the kidney and tumour.
		Because Wilms tumour and hepatoblastoma (liver tumour) are fast growing tumours, it is recommended that all BWS children should have 3 monthly abdominal ultrasound scans.
		As the risk of Wilms tumour diminishes after the age of 7 or 8 years abdominal ultrasound scans need not be continued past this age.
	www.bws-support.org.uk /html/wilms_tumour.html (742 words)

	HON Mother & Child Glossary, Childhood Cancers: Wilms' Tumour (Site not responding. Last check: )
		Wilms' tumour or nephroblastoma is a cancer of the kidneys that can develop in a foetus but may not cause symptoms for years after birth.
		If Wilms' tumour is suspected, an ultrasound, a computed tomography (CT) scan, or a magnetic resonance imaging (MRI) scan may be performed to determine the nature and size of the lump.
		The prognosis depends on the microscopic appearance of the tumour, its spread at the time of diagnosis, and the age of the child.
	www.hon.ch /Dossier/MotherChild/child_cancer/cancer_wilms.html (328 words)

	Intrinsic tumour suppression : Article : Nature
		An especially important mediator of oncogene-dependent activation of p53 is the tumour suppressor ARF (refs 20, 21).
		Consistent with their roles in mediating cell-cycle checkpoints and tumour suppression, both Rb and p53 tumour suppressors are key regulators of the senescence programme.
		Tumour cells harbour mitogenic lesions that drive their proliferation but also confer a propensity towards apoptosis or senescence.
	www.nature.com /uidfinder/10.1038/nature03098 (8384 words)

	txt001kbb: The molecular biology of Wilms’ tumour
		Subsequent LOH studies suggested that there is a tumour suppressor gene on 7p that is involved in at least 10% of WTs (Refs 60, 61, 62).
		Interestingly, LOH studies suggest that the 17q gene is not a tumour suppressor gene (Ref. 65), although it is not yet cloned.
		Mutations in the p53 tumour suppressor gene are frequently associated with adult-onset tumours of the colon, lung, brain and breast.
	www-ermm.cbcu.cam.ac.uk /01003027h.htm (5873 words)

	Pituitary tumour - Better Health Channel.
		A pituitary tumour is a mass of cells that grow on the gland.
		Symptoms are caused by a deficiency in the normal pituitary hormones (because the tumour restricts the function of the normal gland), or by pressure on surrounding structures situated near the pituitary.
		In some cases, the tumour may have to be removed through the front of the skull (craniotomy).
	www.betterhealth.vic.gov.au /bhcv2/bhcarticles.nsf/pages/Pituitary_tumour?OpenDocument (1084 words)

	London Urology Online Bladder tumour surgery
		Sometimes a tumour is seen on ultrasound or X ray examination of the bladder
		If this is the first time the tumour has been diagnosed then the operation will be done under either spinal or general anaesthetic in order to allow removal of some of the bladder muscle beneath the tumour (this confirms the absence of any tumour invasion)
		If the tumour is classified as at higher risk of recurrence we may discuss with you the option of further treatments given into the bladder (no anaesthetic is required for this) prior to your first check cystoscopy.
	www.london-urology.co.uk /bladdertumoursurgery.htm (1612 words)

	Bladder Tumour
		In 90% of the cases, the tumour is transitional cell carcinoma (TCC) arising in the epithelial cells (of the inner lining) of the bladder wall.
		The NMP-22 is associated with tumours of the urogenital tract.
		If the tumour has invaded the muscle layer of the bladder (invasive tumour), it is necessary to radically excise the entire bladder; an alternative way for urine outflow will then have to be devised.
	www.uro-innsbruck.at /uroonkologie/englisch/website_en/iframe_bladdertumour_en.htm (1621 words)

	Brain tumour - Glioma of the Brain
		Brain tumour may be of the Glioma type and usually arise from the glial cells which support the nerve cells.
		Brain tumour treatment usually involves a biopsy and resection of as much tumour as possible, with preservation of normal brain particularly in delicate areas of the brain.
		The brain tumour symptoms that may require attention are headaches which can be treated with standard analgesics.
	www.virtualmedicalcentre.com /diseases.asp?did=532 (681 words)

	Pituitary tumour
		Most of the tumours are not malignant, but because their growth invades other structures, the tumours are considered a neoplasm.
		Pituitary adenomas are the type of pituitary tumour that occurs in about 90% of cases, and the tumour may secrete hormones depending on the cell type of the adenoma.
		Transphenoidal resection (the tumour is accessed through the nose and sinuses) is a procedure used for smaller tumours.
	www.users.bigpond.com /msn/thienc/pituitary.htm (362 words)

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