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Topic: Uridine monophosphate


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RNA

  
  DOXIFLURIDINE (5'-DEOXY-5-FLUOROURIDINE)
Uridine Diphosphate (UDP): a nucleotide, the 5'-pyrophosphate of uridine; acting as the chief transferring coenzyme in carbohydrate metabolism; acting as a carrier of hexoses, hexosamines, and hexuronic acids which are intermediates in the metabolism.
Uridine Triphosphate (UTP): a nucleotide, the 5'-triphosphate of uridine; acting as a precursor in the synthesis of ribonucleic acid and of UDP-linked intermediates.
Deoxyuridine Monophosphate (dUMP): a nucleotide, the 5'-phosphate of deoxyuridine; an intermediate in the synthesis of deoxythymidine triphosphate.
www.chemicalland21.com /lifescience/phar/DOXIFLURIDINE.htm   (753 words)

  
 Dorlands Medical Dictionary
diphosphate (UDP) a nucleotide, the 5′-pyrophosphate of uridine, which serves as a carrier for hexoses, hexosamines, and hexuronic acids in the synthesis of glycogen, glycoproteins, and glycosaminoglycans.
monophosphate (UMP) a nucleotide, the 5′-phosphate of uridine; it is a component of ribonucleic acid.
triphosphate (UTP) a nucleotide, the 5′-triphosphate of uridine; it is an activated precursor in the synthesis of ribonucleic acid and of UDP-linked hexoses involved in glycogen and glycoprotein metabolism.
www.mercksource.com /pp/us/cns/cns_hl_dorlands.jspzQzpgzEzzSzppdocszSzuszSzcommonzSzdorlandszSzdorlandzSzdmd_u_04zPzhtm   (3246 words)

  
 Olympus Microscopy Resource Center: Polarized Light Microscopy Gallery - Uridine
Uridine is one of four nucleosides used in genetic coding for RNA, and its complement is the nucleoside adenosine.
The melting point of purified crystalline needles of uridine, which are soluble in water, is 165 degrees Celsius.
When certain uridine derivatives are, for instance, utilized with organ transplant procedures, the likelihood of organ rejection by the recipient is reduced due to immune system repression.
www.olympusmicro.com /galleries/polarizedlight/pages/uridinesmall.html   (265 words)

  
 Uridine monophosphate - Wikipedia, the free encyclopedia
O[C@H]1[C@H]([C@H] Uridine monophosphate, also known as 5'-uridylic acid and abbreviated UMP, is a nucleotide that is found in RNA.
It is an ester of phosphoric acid with the nucleoside uridine.
UMP consists of the phosphate group, the pentose sugar ribose, and the nucleobase uracil.
en.wikipedia.org /wiki/Uridine_monophosphate   (177 words)

  
 AllRefer.com - uracil (Biochemistry) - Encyclopedia
When combined with the sugar ribose in a glycosidic linkage, uracil forms a derivative called uridine (a nucleoside), which in turn can be phosphorylated with from one to three phosphoric acid groups, yielding respectively the three nucleotides UMP (uridine monophosphate), UDP (uridine diphosphate), and UTP (uridine triphosphate).
The analogous nucleosides and nucleotides formed from uridine and deoxyribose occur only very rarely in living systems; such is not the case with the other pyrimidines.
The nucleotide derivatives of uracil perform important functions in cellular metabolism, particularly in carbohydrate metabolism; UTP acts as a coenzyme in the biosynthesis of sucrose in plants, lactose and glycogen in mammals, and chitin in insects.
reference.allrefer.com /encyclopedia/U/uracil.html   (325 words)

  
 Untitled Document
Incidence of deficiency of uridine monophosphate synthase in dairy bulls.
Incidence and inheritance of deficiency for uridine monophosphate synthase in Holstein bulls.
Embryonic mortality attributed to inherited deficiency of uridine monophosphate synthase.
www.ansci.uiuc.edu /labs/shanks/publications/All.htm   (3876 words)

  
 adenosine triphosphate. The Columbia Encyclopedia, Sixth Edition. 2001-05
ADP can be further broken down to yield adenosine monophosphate (AMP), additional phosphorus, and more energy.
When the phosphorus and energy are immediately used to drive other reactions, such as the synthesis of uridine diphosphate (UDP), an RNA precursor, from uridine monophosphate (UMP), the pair of reactions are said to be coupled.
New ATP is produced from AMP using the energy released from the breakdown of fuel molecules, such as fats and sugars.
www.bartleby.com /65/ad/adenosintp.html   (223 words)

  
 [No title]
The first row shows the interconversions of the uridine nucleotides on the left and the breakdown pathway on the right.
Uridine monophosphate kinase (UMPK) converts UMP to UDP, the general nucleoside diphosphate kinase forms UTP.
It is converted by thymidine kinase (a salvage pathway enzyme) to the monophosphate form.
drnelson.utmem.edu /nucbio2.html   (4071 words)

  
 Cell Biology 1 - Nucleotides   (Site not responding. Last check: 2007-10-20)
Nucleic acids such as RNA and DNA are polymers made from the monomer building blocks called nucleotides, which are made up of a base (5 kinds) + a sugar (2 kinds) + a phosphate.
To be completely correct, nucleic acids are polymers of monophosphate nucleotides.
They are connected via a condensation reaction which creates a phosphodiester bond between sugars.
www.bergen.org /ACADEMY/Bio/cellbio/cellbio1nucleotides.html   (117 words)

  
 Biochemical Evidence for an Ecto Alkaline Phosphodiesterase I in Human Airways -- Picher and Boucher 23 (2): 255 -- ...
uridine triphosphate > guanidine triphosphate > cytidine triphosphate).
the accumulation of AMP and the conversion of the monophosphate
UDP; uridine monophosphate, UMP; uridine triphosphate, UTP, P
ajrcmb.atsjournals.org /cgi/content/full/23/2/255   (4676 words)

  
 Olympus Microscopy Resource Center: Polarized Light Microscopy Gallery - Uridine
Olympus Microscopy Resource Center: Polarized Light Microscopy Gallery - Uridine
Each molecule of uridine is comprised of 9 carbons, 12 hydrogens, 2 nitrogens, and 6 oxygen atoms, resulting in a molecular weight of 244.20.
Within the body, the nucleoside plays an important role in the metabolism of carbohydrates, and, in the laboratory, the white odorless powder that can be extracted from yeast ribonucleic acids using a weak alkali solution is utilized in a variety of biochemical experiments and studies.
www.olympusmicro.com /galleries/polarizedlight/pages/uridinelarge.html   (116 words)

  
 Electrostatic stress in catalysis: Structure and mechanism of the enzyme orotidine monophosphate decarboxylase -- Wu et ...
Electrostatic stress in catalysis: Structure and mechanism of the enzyme orotidine monophosphate decarboxylase -- Wu et al.
Electrostatic stress in catalysis: Structure and mechanism of the enzyme orotidine monophosphate decarboxylase
In summary, we have determined the crystal structure of orotidine monophosphate decarboxylase and, based on it, propose a
www.pnas.org /cgi/content/full/97/5/2017   (4014 words)

  
 [No title]
Free purine bases can be recycled by coupling with the ribose phosphate moiety, 5-phospho-ribosyl-1-pyrophosphate (PRPP), to form nucleotide monophosphates:   Biodegradation of Purines Nucleotides undergo continual turnover in a cell.
The O4 of the uridine is phosphorylated, followed by displacement with ammonia.
Orotic acidurea: a rare disease associated with defects in pyrimidine biosynthesis — Symptoms: anemia, growth retardation, orotic acid excretion in urine.
www.pharmacy.umn.edu /img/assets/12621/biosyn_nucleotides_handout1-04a.doc   (2415 words)

  
 Bioc 811
After all, U and T both pair with A, so this is no problem (see pp.
The nucleosides or deoxynucleosides can be phosphorylated by uridine kinase, to make UMP and CMP (uridine kinase acts on both uridine and cytidine) deoxycytidine kinase to make dCMP and thymidine kinase to make dTMP.
This is further phosphorylated to the triphosphate form by thymidylate kinase and NDP kinase.
drnelson.utmem.edu /nucbio2.2002.html   (4091 words)

  
 biology - Nucleotide
Nucleotides also play important roles in cellular energy transport and transformations (notably ATP and NAD+/NADH), and in enzyme regulation (see for example, protein kinase).
The nucleobase can be a purines or pyrimidines, the sugar can be deoxyribose in DNA or ribose in RNA, and the phosphate chain can be a monophosphate, diphosphate, or triphosphate.
A nucleotide that lacks the phosphate group is called nucleoside.
www.biologydaily.com /biology/Nucleotide   (198 words)

  
 Technical data sheet - AP8129a
UCK1 (Uridine-cytidine kinase 1) phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate.
UCK1 also possesses the ability to phosphorylate a number of cytidine and uridine nucleoside analogs such as 6-azauridine, 5-fluorouridine, 4-thiouridine, 5-bromouridine, N(4)-acetylcytidine, N(4)-benzoylcytidine, 5-fluorocytidine, 2-thiocytidine, 5-methylcytidine, and N(4)-anisoylcytidine.
The data only shows the application of the antibody for immunohistochemistry therefore the clinical relevance needs to be further investigated.
www.abgent.com /print/AP8129a   (255 words)

  
 DUMPS   (Site not responding. Last check: 2007-10-20)
DUMPS is an inherited condition that occurs in Holstein cattle.
DUMPS stands for deficiency of uridine monophosphate synthase, an enzyme found in all body cells.
Enzymes are proteins that catalyze the various biological reactions associated with living things.
www.immgen.com /Services/Traits/DUMPS.html   (319 words)

  
 uracil
When combined with the sugar ribose in a glycosidic linkage, uracil forms a derivative called uridine (a nucleoside), which in turn can be phosphorylated with from one to three phosphoric acid groups, yielding respectively the three
UMP (uridine monophosphate), UDP (uridine diphosphate), and UTP (uridine triphosphate).
The nucleotide derivatives of uracil perform important functions in cellular metabolism, particularly in carbohydrate metabolism; UTP acts as a
www.factmonster.com /ce6/sci/A0850156.html   (228 words)

  
 Ch432_Lec_25Feb
RNA uses AMP, CMP, GMP, and UMP, while DNA use the deoxy forms: dAMP, dCMP, dGMP, and dTMP.
Note that the two nucleic polymers differ by both the 2'functional group (-OH or -H) and the use of either uridine or thymine as the fourth base.
The structures of the bases are shown in the table below.
www.humboldt.edu /~rap1/C432.S02/C432Notes/C432n25feb.html   (414 words)

  
 Uridine monophosphate definition - Medical Dictionary definitions of popular medical terms
Uridine monophosphate definition - Medical Dictionary definitions of popular medical terms
Uridine monophosphate: (UMP) A molecular ion derived from uridylic acid.
Please consult your healthcare provider before beginning any course of supplementation or treatment.
www.medterms.com /script/main/art.asp?articlekey=39061   (135 words)

  
 nucleic acids
The monophosphorylated form of adenosine found in DNA (deoxyadenosine-5'-monophosphate) is written as
The nucleotide uridine is never found in DNA and thymine is almost exclusively found in DNA.
Thymine is found in tRNAs but not rRNAs nor mRNAs.
www.med.unibs.it /~marchesi/nucleic.html   (1879 words)

  
 Structure-function relationships of UMP kinases from pyrH mutants of Gram-negative bacteria -- Sakamoto et al. 150 (7): ...
Ingraham, J. and Neuhard, J. Cold-sensitive mutants of Salmonella typhimurium defective in uridine monophosphate kinase (pyrH).
Jensen, K. Regulation of Salmonella typhimurium pyr gene expression: effect of changing both purine and pyrimidine nucleotide pools.
Liljelund, P. and Lacroute, F. Genetic characterization and isolation of the Saccharomyces cerevisiae gene coding for uridine monophosphokinase.
mic.sgmjournals.org /cgi/content/full/150/7/2153   (3362 words)

  
 Pai Lab - Structure Gallery   (Site not responding. Last check: 2007-10-20)
Orotidine 5'-Phosphate Decarboxylase Mutant D70A In Complex With Uridine 5'-Monophosphate
Orotidine 5'-Phosphate Decarboxylase Mutant K72A In Complex With Uridine 5'-Monophosphate
Orotidine 5'-Phosphate Decarboxylase In Complex With Uridine 5'-Monophosphate
gene4d.med.utoronto.ca /gallery.html   (651 words)

  
 URA6: cerevisiae : GeneDB   (Site not responding. Last check: 2007-10-20)
Want some sort of link based on Pfam PF00406 here.
Uridylate kinase (EC 2.7.4.-) (UK) (Uridine monophosphate kinase) (UMP kinase).
Saccharomyces cerevisiae uridine monophosphate kinase (URA6) gene, complete cds.
www.genedb.org /genedb/Search?organism=cerevisiae&name=YKL024C   (192 words)

  
 Cluster HCC04638   (Site not responding. Last check: 2007-10-20)
2e-38 Contig_01_P13439 Q99L26 AAH03887.1 AAA39859.1 Desc: Uridine 3e-38 Contig_01_BAC29199 BAC29199.1 Desc: 16 days neonate cerebellum c 3e-38 Contig_01_Q9LKI3 AAF86340.1 Desc: UMP synthase.
7e-38 Contig_04_Q9LDN2 BAA92171.1 AAF61490.1 AAF61491.1 BAB86207.1 Des 9e-38 Contig_01_Q42942 AAC49115.1 Desc: Uridine 5-monophosphate 2e-37 Contig_03_Q9LDN2 BAA92171.1 AAF61490.1 AAF61491.1 BAB86207.1 Des 2e-37 Contig_03_Q9LKI3 AAF86340.1 Desc: UMP synthase.
2e-37 Contig_02_Q42942 AAC49115.1 Desc: Uridine 5-monophosphate 3e-37 Contig_04_Q42942 AAC49115.1 Desc: Uridine 5-monophosphate 3e-37 Contig_01_Q9LDN2 BAA92171.1 AAF61490.1 AAF61491.1 BAB86207.1 Des 5e-37 Contig_03_Q42942 AAC49115.1 Desc: Uridine 5-monophosphate 8e-37
nema.cap.ed.ac.uk /nematodeESTs/cluster.php?cluster=HCC04638   (158 words)

  
 At3g54470 -   (Site not responding. Last check: 2007-10-20)
These synonyms are used for gene At3g54470 (): PYRE-F, T14E10_40, T14E10.40, UMPS, UMP synthase, Uridine 5'-monophosphate synthase.
At3g54470 is a homologue of Umps (uridine monophosphate synthetase) from Mus musculus.
At3g54470 is a homologue of UMPS (uridine monophosphate synthetase (orotate phosphoribosyl transferase and orotidine-5'-decarboxylase)) from Homo sapiens.
www.ihop-net.org /UniPub/iHOP/gg/9957.html   (100 words)

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