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| | Chapter 3-2 (Site not responding. Last check: 2007-10-29) |
 | | The introduction of chemical anesthetic agents to abolish surgical pain occurred in an epoch‑making five‑year period between 1842 an 1847, though the first of these agents, diethyl ether, had been known for hundreds of years. |
 | | In 1540 an alchemist, Valerius Cordus, gave the earliest account of the synthesis of this fluid, which he called oleum dulci vitrioli or "sweet oil of vitriol." To "very biting wine (ethyl alcohol) "sour oil of vitriol" (sulfuric acid) was added. |
 | | Cordus found that sweet vitriol was an excellent solvent for many substances, and noted that it "may be used in pleurisy, peri-pneumonia, and hacking cough to draw from the lungs pus and mucus." F. Frobenius, a German chemist, gave sweet vitriol the name "ether" in 1730. |
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