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Topic: Vasculitis

Related Topics

Vascular constriction

Polyarteritis nodosa

Giant cell arteritis

Paraneoplastic phenomenon

Autoimmune disease

Blood vessel

Pulmonology

Brain cancer

Myocarditis

Rheumatology

Vascular

Inflammatory bowel disease

Immune system

Cardiology

Inflammation

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	Vasculitis
		Vasculitis refers to a varied group of disorders which all share a common underlying problem of inflammation of a blood vessel or blood vessels.
		Some types of vasculitis are so mild that the only symptoms noted are small reddish-purple dots (called petechiae) on the skin due to tiny amounts of blood seeping out of leaky blood vessels.
		Other types of vasculitis were always fatal, prior to the availability of prednisone and cyclophosphamide, and continue to have high rates of fatal complications.
	www.lifesteps.com /gm/Atoz/ency/vasculitis.jsp (1930 words)

	Lupus and Vasculitis (Site not responding. Last check: 2007-11-07)
		Vasculitis is an inflammation of the blood vessels.
		In the vasculitis caused by lupus, the antigens causing the immune complexes are often not known.
		Vasculitis in the coronary arteries is unusual in lupus.
	www.hamline.edu /lupus/articles/vasculitis.html (1742 words)

	MedlinePlus Medical Encyclopedia: Allergic vasculitis
		Allergic vasculitis is hypersensitivity to a drug or foreign agent that leads to inflammation and damage to blood vessels of the skin.
		Vasculitis occurs because of inflammation and damage to blood vessels.
		The inflammation of allergic vasculitis is the result of an allergic reaction to a drug or other foreign agent.
	www.nlm.nih.gov /medlineplus/ency/article/000874.htm (405 words)

	Nat'l Jewish-Med. Sci. Update-Vasculitis (Site not responding. Last check: 2007-11-07)
		Although the most common cause of vasculitis is a secondary hypersensitivity reaction that resolves when the primary disease is treated, other vasculitides are primary diseases that require aggressive immunomodulatory therapy.
		Diagnosing vasculitis is a clinical challenge because it is a syndrome, not a specific disease.
		Vasculitis may also be associated with a primary illness, including rheumatic and connective tissue diseases, cancer, infectious diseases, and inflammatory bowel disease.
	library.nationaljewish.org /MSU/12n5MSU_Vasculitis.html (2270 words)

	CNS Vasculitis
		Vasculitis (meaning inflammation of the blood vessels) confined to the brain, the spinal cord and its covering is referred to as central nervous system vasculitis.
		The signs and symptoms of CNS vasculitis are similar to those encountered in having a stroke because they result from a reduction or sudden stoppage of blood flow to the brain.
		The symptoms of CNS vasculitis may be extremely difficult to separate from more common forms of neurologic disease such as multiple stokes from hardening of the arteries (atherosclerosis), emboli (dislodged blood clots that travel to the brain from the heart or large blood vessels in the neck), infections or even multiple sclerosis.
	www.clevelandclinic.org /arthritis/treat/facts/cns.htm (1266 words)

	Info and facts on 'Vasculitis' (Site not responding. Last check: 2007-11-07)
		In medicine (The branches of medical science that deal with nonsurgical techniques), vasculitis (plural: vasculitides) is a group of diseases featuring inflammation (A response of body tissues to injury or irritation; characterized by pain and swelling and redness and heat) of the wall of blood vessel (A vessel in which blood circulates) s.
		Its main causes are autoimmune disorder (Any of a large group of diseases characterized by abnormal functioning of the immune system that causes your immune system to produce antibodies against your own tissues) s and (occasionally) infection (The pathological state resulting from the invasion of the body by pathogenic microorganisms) s.
		For very severe forms, bone marrow transplantation (additional info and facts about bone marrow transplantation) is presently being investigated as the ultimate silencing of the immune system (A system (including the thymus and bone marrow and lymphoid tissues) that protects the body from foreign substances and pathogenic organisms by producing the immune response).
	www.absoluteastronomy.com /encyclopedia/v/va/vasculitis.htm (465 words)

	Vasculitis
		The effects of vasculitis depend on the sizes of the blood vessels that are affected and on the parts of the body involved.
		Vasculitis is not a hereditary disease and it does not run in families.
		Vasculitis in the heart may result in symptoms similar to a heart attack, and in the brain it may cause confusion, symptoms of a stroke or fits.
	renux.dmed.ed.ac.uk /EdREN/EdRenINFObits/VasculitisLong.html (1040 words)

	Arthritis Research Campaign \| Vasculitis (Site not responding. Last check: 2007-11-07)
		Vasculitis in the small arteries can also be a consequence of rheumatic diseases, including rheumatoid arthritis and systemic lupus erythematosus.
		Vasculitis in small vessels (usually capillaries) – this usually involves the skin and is also sometimes caused by a reaction to certain drugs.
		If you have small-vessel vasculitis which only affects the skin, it may be that the only action needed is to treat any underlying infection or to remove the drug or food that triggered the vasculitis.
	www.arc.org.uk /about_arth/booklets/6047/6047.htm (4395 words)

	Postgraduate Medicine: Symposium: Rheumatologic Diseases
		The categorization of vasculitis by the size of the involved blood vessels is a useful guide to diagnosis and therapy(1-3) (table 1).
		Vasculitis should be suspected in any patient presenting with a multisystem disease that is not readily explained by an infectious or malignant process.
		Large vessels are involved in two types of vasculitis: Temporal arteritis affects the extracranial, ophthalmic, and aortic arch vessels (20), and Takayasu's arteritis affects vessels of the aortic arch and its branches (21).
	www.postgradmed.com /issues/1998/02_98/bush.htm (3250 words)

	EHS: Magnetic Resonance Imaging - Sample Chapter 55: Ischemia, 7
		Vasculitis is characterized by necrosis and inflammation of the vessel wall that can eventually result in segmental alteration of the vessel caliber, occlusion, aneurysm, and areas of hypervascularity.
		The vasculitis may be the primary disease process (e.g., polyarteritis nodosa) or may be a secondary manifestation of a generalized systemic disease (e.g., systemic lupus erythematosus).
		The angiographic appearance of vasculitis is often nonspecific and can be mimicked by such varied entities as atherosclerosis, vasospasm as a result of subarachnoid hemorrhage, and neoplastic vascular involvement (e.g., gliomas and lymphomas).
	www3.us.elsevierhealth.com /Mosby/Stark-Bradley/C88_055g.html (1578 words)

	Lupus And Vasculitis - Lupus Foundation of America, Inc.
		For example, a person with vasculitis of a medium-sized artery in the hand may develop a cold finger which hurts whenever it is used.
		Vasculitis in the kidneys may not cause any symptoms, although most patients with renal vasculitis have high blood pressure.
		The diagnosis of vasculitis is most firmly made by taking a biopsy of the involved tissue and examining that tissue under a microscope.
	www.lupus.org /education/brochures/vasculitis.html (1593 words)

	Lupus And Vasculitis (Site not responding. Last check: 2007-11-07)
		For example, a person with vasculitis of a mediumsized artery in the hand may develop a cold finger which hurts whenever it is used; occasionally this can progress to gangrene.
		Vasculitis can be caused by (1) infection of the blood vessel walls, or (2) an immune or "allergic" reaction in the vessel walls.
		Some people with severe vasculitis or vasculitis that does not respond well to cortisone-type drugs will need to be treated with cytotoxic drugs.
	www.hamline.edu /lupus/articles/Lupus_and_Vasculitis.html (1775 words)

	[Frontiers in Bioscience 9, 946-955, January 1, 2004] (Site not responding. Last check: 2007-11-07)
		Vasculitis of the central nervous system can be of several varieties depending upon the vessel(s) involved and type of disorder.
		One can see primary CNS vasculitis as a distinct entity which is primarily manifested as central nervous system injury in a vascular distribution or the vasculitic process can be secondary to a systemic disorder such as systemic lupus erythematosus (SLE) or polyarteritis nodosa (PAN).
		Key to the recognition and treatment of CNS vasculitis is the evolution of newer insights into the pathogenesis.
	www.bioscience.org /2004/v9/af/1259/3.htm (265 words)

	eMedicine - Leukocytoclastic Vasculitis : Article by Jeffrey P Callen, MD (Site not responding. Last check: 2007-11-07)
		Hepatitis C is a regularly recognized cause of vasculitis, probably through the presence of cryoglobulins; however, in the past, hepatitis B was implicated in some cases of vasculitis.
		Hepatitis B was associated with vasculitis in the past; however, it appears that the association may have occurred by virtue of co-infection with hepatitis C (previously termed non-A/non-B hepatitis).
		Vasculitis may be complicated by ulceration of the skin or by end-organ dysfunction.
	www.emedicine.com /med/topic2930.htm (3772 words)

	Baylor Neurology Case of the Month (Site not responding. Last check: 2007-11-07)
		Although the "gold standard" for all forms of vasculitis is histologic confirmation, a recent review by Calabrese et al., suggests that nearly one in four biopsy procedures may result in a false-negative outcome.
		Therefore, after discussion with the patient and his family, the decision was made to treat for CNS vasculitis and forego the risk involved with brain and leptomeningeal biopsy.
		CNS vasculitis was first described as a distinct entity by Cravioto and Feigin in 1959 and was named granulomatous angiitis, reflecting the presence of prominent granulomata.
	www.bcm.tmc.edu /neurol/challeng/pat5/summary.html (1810 words)

	Introduction: Vasculitic Disorders of Connective Tissue: Merck Manual Home Edition
		Vasculitis commonly occurs in disorders that affect connective tissue, but it can also occur in conditions that do not affect connective tissue.
		Vasculitis is not a disease but rather a disease process.
		Vasculitis may be limited to veins, large arteries, small arteries, or capillaries, or it may be limited to vessels in one part of the body, such as the head, leg, or kidney.
	www.merck.com /mmhe/sec05/ch069/ch069a.html (385 words)

	Editorial
		Among these are a lack of: clinical signs and symptoms of high specificity, efficient noninvasive diagnostic tests, relevant animal models, extremely limited biologic materials for pathophysiologic investigation, longterm followup of large numbers of patients, and controlled therapeutic trials.
		Despite such limitations, vasculitis of the CNS in general and primary angiitis of the CNS (PACNS) in particular have become the subject of increasing interest to clinicians driven in large part by increased awareness, coupled to our growing sophistication and aggressive use of neurodiagnostic modalities.
		The authors chose to secure the diagnosis angiographically because most of the mimicking diseases seen in adults are rare in children and because of the risks of biopsy.
	www.jrheum.com /abstracts/editorials01/465.html (1345 words)

	Brain Inflammation
		It starts as a necrotizing vasculitis of the nose and sinuses, and spreads by direct invasion of adjacent facial compartments.
		Vasculitis and cerebral infarction, caused by inflammatory changes in the basal cisterns, are more prevalent.
		The MR features of tuberculous meningitis are similar to the bacterial agents, but the chronic inflammation induces thick granulation tissue that produces a more striking enhancement pattern.
	spinwarp.ucsd.edu /NeuroWeb/Text/br-200.htm (3690 words)

	Baylor Neurology Case of the Month (Site not responding. Last check: 2007-11-07)
		Patient # 29 presented with the gradual onset of weight loss, rash, joint pains, and an elevated rheumatoid factor consistent with a diagnosis of rheumatoid arthritis and the rapid onset of neurological compromise evidenced by gait difficulty, diffuse and focal weakness, and impaired cognition.
		The remaining possibilities of a diffuse demyelinating process or CNS vasculitis could not be differentiated on the basis of the foregoing tests, however.
		And CNS vasculitis secondary to rheumatoid arthritis is extremely rare, with only a few cases reported in the literature.
	www.bcm.tmc.edu /neurol/challeng/pat29/summary.html (1666 words)

	HSS - New Treatment Strategies for Systemic Vasculitis (Site not responding. Last check: 2007-11-07)
		I will tell you that in our practice at the Vasculitis Center at the Cleveland Clinic, one of the greatest pitfalls in the management of vasculitis that we see of patients referred into us, are the patients who are "Cytoxan failures." Virtually all of these patients come in with active disease on pulse therapy.
		The primary outcome of this study was the Birmingham Vasculitis Activity Score, which for those of you who are not well familiar with, it is basically an enumeration on a target organ basis of new clinical events that are ascribed by the investigator to be due to vasculitis, not therapy or intercurrent illness.
		Well, the model of using thalidomide in vasculitis is you know ENL, which pathologically is a necrotizing vasculitis in the deep dermis, and it makes it an appealing target.
	rheumatology.hss.edu /phys/gr/calabrese_lec_tran.asp (7301 words)

	Johns Hopkins Vasculitis Center
		“Vasculitis” is a general term for a group of diseases that involve inflammation in blood vessels.
		Blood vessels of all sizes may be affected, from the largest vessel in the body (the aorta) to the smallest blood vessels in the skin (capillaries).
		The purpose of this Website is to provide information about vasculitis, to inform readers about the Vasculitis Center, and to let patients know where to find more information.
	vasculitis.med.jhu.edu (185 words)

	Are T1- and T2-Weighted Spin-Echo MR Images Sufficient for the Diagnosis of Central Nervous System Vasculitis? -- ...
		Diagnosing intracranial vasculitis: the roles of MR and angiography.
		CNS vasculitis in autoimmune disease: MR imaging and correlation with angiography.
		MR imaging of vasculitis of the central nervous system [1].
	www.ajronline.org /cgi/content/full/179/1/273 (1089 words)

	Neurology of the vasculitides and connective tissue diseases -- Moore and Richardson 65 (1): 10 -- Journal of ...
		Wegener's granulomatosis is characterised by a necrotising, granulomatous vasculitis of the upper and lower respiratory tract,
		Isolated angiitis of the CNS is an idiopathic vasculitis affecting blood vessels of the CNS within the dural reflections.
		Vasculitis of the nervous system secondary to a known cause or underlying process is both frequent and clinically important.
	jnnp.bmjjournals.com /cgi/content/full/65/1/10 (7323 words)

	Postgraduate Medicine: Pearls in Dermatology
		Henoch-Schönlein purpura is a variant of leukocytoclastic vasculitis that may be triggered by an upper respiratory tract infection (1).
		The disease often occurs in the spring, primarily affects children and young adults, and is characterized by palpable purpura, arthritis, hematuria, and abdominal pain (1-5).
		Other therapies reported to be of benefit include nonsteroidal anti-inflammatory drugs (7), minocycline (Minocin) for vasculitis associated with rheumatoid arthritis (11), and plasmapheresis and interferon therapy for vasculitis associated with hepatitis C and cryoglobulinemia (4).
	www.postgradmed.com /issues/1999/03_99/pd_arvan.htm (1074 words)

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